Novel Therapies In Hepatitis C Virus An Issue Of Clinics In Liver Disease

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Eliminating the Public Health Problem of Hepatitis B and C in the United States

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309438020
Total Pages : 187 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Eliminating the Public Health Problem of Hepatitis B and C in the United States by : National Academies of Sciences, Engineering, and Medicine

Download or read book Eliminating the Public Health Problem of Hepatitis B and C in the United States written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-06-01 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world's hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common types, surpassed HIV and AIDS to become the seventh leading cause of death worldwide. The world now has the tools to prevent hepatitis B and cure hepatitis C. Perfect vaccination could eradicate HBV, but it would take two generations at least. In the meantime, there is no cure for the millions of people already infected. Conversely, there is no vaccine for HCV, but new direct-acting antivirals can cure 95 percent of chronic infections, though these drugs are unlikely to reach all chronically-infected people anytime soon. This report, the first of two, examines the feasibility of hepatitis B and C elimination in the United States and identifies critical success factors. The phase two report will outline a strategy for meeting the elimination goals discussed in this report.

Novel and Combination Therapies for Hepatitis C Virus, An Issue of Clinics in Liver Disease

Author : Paul J. Pockros
Publisher : Elsevier Health Sciences
ISBN 13 : 1455771988
Total Pages : 245 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Novel and Combination Therapies for Hepatitis C Virus, An Issue of Clinics in Liver Disease by : Paul J. Pockros

Download or read book Novel and Combination Therapies for Hepatitis C Virus, An Issue of Clinics in Liver Disease written by Paul J. Pockros and published by Elsevier Health Sciences. This book was released on 2013-02-28 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Pockros has created a clinically focused issue based on the CONO 2012 meeting, whereby he was able to have those presenters write articles for his issue. Therefore, the content for HCV in this issue reflects the most current knowledge. The issue is focused on basic/current information, current therapy and special populations, triple and quad combination therapies in development, and an article on second generation protease inhibitors. The reader can expect that this issue will provide thorough clinical reviews on the most current therapeutic options for HCV.

Hepatitis and Liver Cancer

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309153689
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hepatitis and Liver Cancer by : Institute of Medicine

Download or read book Hepatitis and Liver Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 2010-04-23 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Chronic Liver Failure

Author : Pere Ginès
Publisher : Springer Science & Business Media
ISBN 13 : 1607618664
Total Pages : 583 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Chronic Liver Failure by : Pere Ginès

Download or read book Chronic Liver Failure written by Pere Ginès and published by Springer Science & Business Media. This book was released on 2010-11-03 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.

Guidelines on Hepatitis B and C Testing

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9789241549981
Total Pages : 0 pages
Book Rating : 4.5/5 (499 download)

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Book Synopsis Guidelines on Hepatitis B and C Testing by : World Health Organization

Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.

The Hepatitis C Help Book

Author : Misha Ruth Cohen
Publisher : Dearborn Trade Publishing
ISBN 13 : 9780312263362
Total Pages : 308 pages
Book Rating : 4.2/5 (633 download)

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Book Synopsis The Hepatitis C Help Book by : Misha Ruth Cohen

Download or read book The Hepatitis C Help Book written by Misha Ruth Cohen and published by Dearborn Trade Publishing. This book was released on 2001-05-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatitis C has been called "the emergent and preeminent public-health problem of the twenty-first century-surpassing HIV." It has also been dubbed "The Shadow Epidemic," because it is one of the most clandestine of viruses and infects healthy people who have no idea they are being attacked by something they can't even detect. Now, two experts on hepatitis C have teamed up to write a complete guide to orthodox and alternative treatment options. The book includes programs for self-care, nutritional and fitness plans, and a comprehensive Western and Chinese medical treatment program.

Chronic Hepatitis C Virus

Author : Mitchell L. Shiffman
Publisher : Springer Science & Business Media
ISBN 13 : 1461411920
Total Pages : 333 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Chronic Hepatitis C Virus by : Mitchell L. Shiffman

Download or read book Chronic Hepatitis C Virus written by Mitchell L. Shiffman and published by Springer Science & Business Media. This book was released on 2011-11-17 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Fatty Liver Disease

Author : Geoffrey C. Farrell
Publisher : John Wiley & Sons
ISBN 13 : 140514100X
Total Pages : 336 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Fatty Liver Disease by : Geoffrey C. Farrell

Download or read book Fatty Liver Disease written by Geoffrey C. Farrell and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fatty Liver Diseases: NASH and Related Disorders is an unusual book: it combines a practical approach for students and physicians concerned with the problem with a clear overview on the causative mechanisms. It appeals to doctors and other health care workers who encounter this problem, as well as to pathologists and investigators interested in the field of liver disease. It will improve your diagnostic acumen for people with abnormal liver tests, advance your knowledge about this important subject and help with your specialist or undergraduate exams, and management of a common disorder.

Novel Therapies in Hepatitis C Virus, an Issue of Clinics in Liver Disease

Author : Paul J. Pockros
Publisher : Saunders
ISBN 13 : 9781437712360
Total Pages : 0 pages
Book Rating : 4.7/5 (123 download)

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Book Synopsis Novel Therapies in Hepatitis C Virus, an Issue of Clinics in Liver Disease by : Paul J. Pockros

Download or read book Novel Therapies in Hepatitis C Virus, an Issue of Clinics in Liver Disease written by Paul J. Pockros and published by Saunders. This book was released on 2009-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guest Editor presents state-of-the-art articles devoted to therapies for treatment of HCV. The novel therapies addressed in this issue include interferons, viral kinetics and anti-viral resistence, anti-fibrotics, immunotherapeutics, hepatoprotectants and caspace inhibitors, and cyclosporine analogues, to name a few.

Drug-Induced Liver Injury

Author :
Publisher : Academic Press
ISBN 13 : 0128173173
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug-Induced Liver Injury by :

Download or read book Drug-Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

New Drug Development for Known and Emerging Viruses

Author : Helga Rübsamen-Schaeff
Publisher : John Wiley & Sons
ISBN 13 : 3527810706
Total Pages : 530 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis New Drug Development for Known and Emerging Viruses by : Helga Rübsamen-Schaeff

Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2021-11-30 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.

Hepatitis B Virus, An Issue of Clinics in Liver Disease

Author : Tarek I. Hassanein
Publisher : Elsevier Health Sciences
ISBN 13 : 0323477054
Total Pages : 161 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Hepatitis B Virus, An Issue of Clinics in Liver Disease by : Tarek I. Hassanein

Download or read book Hepatitis B Virus, An Issue of Clinics in Liver Disease written by Tarek I. Hassanein and published by Elsevier Health Sciences. This book was released on 2016-10-15 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: HBV is most prevalent viral infection worldwide. Recent advances in HBV virology epidemiology and management are of utmost importance particularly during this time when HCV is taking the front row in discussion and research. However, there’s an increased interest in management of HBV in special populations, which is covered in this issue. The authors also explore drugs in the pipeline as well as new approaches for achieving long-term viral suppression and possibly cure.

Consultations in Liver Disease, An Issue of Clinics in Liver Disease, E-Book

Author : Steven L. Flamm
Publisher : Elsevier Health Sciences
ISBN 13 : 0323961339
Total Pages : 185 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Consultations in Liver Disease, An Issue of Clinics in Liver Disease, E-Book by : Steven L. Flamm

Download or read book Consultations in Liver Disease, An Issue of Clinics in Liver Disease, E-Book written by Steven L. Flamm and published by Elsevier Health Sciences. This book was released on 2022-11-18 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Clinics in Liver Disease, guest editor Dr. Steven L. Flamm brings his considerable expertise to the topic of Updates in Consultations in Liver Disease. Many disease entities are uncommon and complicated in scope, and liver disease may occur in the setting of other chronic medical conditions and involve other organ systems. In this issue, top experts provide a up-to-date framework for approaching consultation for common liver-related problems for the gastroenterology and hepatology practitioner. - Contains 12 practice-oriented topics including clinical pearls in evaluation and treatment of patients with liver disease; evaluation of patients with markedly elevated liver enzymes; evaluation of liver disease in pregnancy; COVID and implications on the liver; and more. - Provides in-depth clinical reviews on consultations in liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease

Author : Cynthia Levy
Publisher : Elsevier Health Sciences
ISBN 13 : 1455771996
Total Pages : 244 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease by : Cynthia Levy

Download or read book Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease written by Cynthia Levy and published by Elsevier Health Sciences. This book was released on 2013-05-28 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.

Consultations in Liver Disease, An Issue of Clinics in Liver Disease

Author : Steven L. Flamm
Publisher : Elsevier Health Sciences
ISBN 13 : 0323354610
Total Pages : 241 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Consultations in Liver Disease, An Issue of Clinics in Liver Disease by : Steven L. Flamm

Download or read book Consultations in Liver Disease, An Issue of Clinics in Liver Disease written by Steven L. Flamm and published by Elsevier Health Sciences. This book was released on 2014-12-24 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.

Current Management of Hepatitis C Virus, An Issue of Clinics in Liver Disease

Author : Fred Poordad
Publisher : Elsevier Health Sciences
ISBN 13 : 0323413374
Total Pages : 145 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Current Management of Hepatitis C Virus, An Issue of Clinics in Liver Disease by : Fred Poordad

Download or read book Current Management of Hepatitis C Virus, An Issue of Clinics in Liver Disease written by Fred Poordad and published by Elsevier Health Sciences. This book was released on 2016-01-07 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical information about Hepatitis C is quickly outdated, so Dr. Poordad has assembled expert authors to provide state-of-the-art clinjcal reviews for hepatologists. This issue is uniquely organized to present articles based on therapeutic regimens for certain types of patients: Regimens for the Treatment-Naïve Patient; Regimens for Treatment of the Interferon-Failure Patient; Regimens for DAA Failure Patients; Regimens for the Cirrhotic Patient; Regimens for the Peri-Transplant Patient; Regimens for the HIV-Co-Infected Patient; and Next-generation Regimens: The Future of HCV Therapy. This presentation will be very clinically relevant for the practicing hepatologist.

Novel and Combination Therapies for Hepatitis C Virus, an Issue of Clinics in Liver Disease

Author : Paul J. Pockros
Publisher : Clinics: Internal Medicine
ISBN 13 : 9781455771127
Total Pages : 0 pages
Book Rating : 4.7/5 (711 download)

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Book Synopsis Novel and Combination Therapies for Hepatitis C Virus, an Issue of Clinics in Liver Disease by : Paul J. Pockros

Download or read book Novel and Combination Therapies for Hepatitis C Virus, an Issue of Clinics in Liver Disease written by Paul J. Pockros and published by Clinics: Internal Medicine. This book was released on 2012-12-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Pockros has created a clinically focused issue based on the CONO 2012 meeting, whereby he was able to have those presenters write articles for his issue. Therefore, the content for HCV in this issue reflects the most current knowledge. The issue is focused on basic/current information, current therapy and special populations, triple and quad combination therapies in development, and an article on second generation protease inhibitors. The reader can expect that this issue will provide thorough clinical reviews on the most current therapeutic options for HCV.