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Novel Drug Delivery Approaches In Dry Eye Syndrome Therapy
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Book Synopsis Ophthalmic Drug Delivery Systems by : Ashim K. Mitra
Download or read book Ophthalmic Drug Delivery Systems written by Ashim K. Mitra and published by CRC Press. This book was released on 2019-12-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.
Book Synopsis Microneedles for Drug and Vaccine Delivery and Patient Monitoring by : Ryan F. Donnelly
Download or read book Microneedles for Drug and Vaccine Delivery and Patient Monitoring written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2018-06-04 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.
Book Synopsis Bio-Targets and Drug Delivery Approaches by : Sabyasachi Maiti
Download or read book Bio-Targets and Drug Delivery Approaches written by Sabyasachi Maiti and published by CRC Press. This book was released on 2016-11-03 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances in drug delivery systems over recent years have resulted in a large number of novel delivery systems with the potential to revolutionize the treatment and prevention of diseases. Bio-Targets and Drug Delivery Approaches is an easy-to-read book for students, researchers and pharmaceutical scientists providing a comprehensive introduction to the principles of advanced drug delivery and targeting their current applications and potential future developments.
Book Synopsis Ocular Surface Disorders by : Jose M Benitez-del-Castillo
Download or read book Ocular Surface Disorders written by Jose M Benitez-del-Castillo and published by JP Medical Ltd. This book was released on 2013-11-04 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current knowledge of the epidemiology, clinical expression, pathophysiology and available medical and surgical therapy for ocular surface diseases, providing an invaluable text for ocular surface specialists, general ophthalmologists, optometrists and residents.
Book Synopsis Intraocular Drug Delivery by : Glenn J. Jaffe
Download or read book Intraocular Drug Delivery written by Glenn J. Jaffe and published by CRC Press. This book was released on 2006-03-13 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-r
Book Synopsis Bioadhesives in Drug Delivery by : K. L. Mittal
Download or read book Bioadhesives in Drug Delivery written by K. L. Mittal and published by John Wiley & Sons. This book was released on 2020-05-12 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important and unique book comprises 12 chapters divided into three parts examining the fundamental aspects, bioadhesive formulations, and drug delivery applications. Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the delivery system to the site of interest and thus offers a useful and efficient technique for targeting a drug to the desired location for a prolonged duration. This book addresses the various relevant aspects of bioadhesives in drug delivery in an easily accessible and unified manner. The book containing 12 chapters written by eminent researchers from many parts of the globe is divided into three parts: Part 1: Fundamental Aspects; Part 2: Bioadhesive Formulations; Part 3: Drug Delivery Applications. The topics covered include: Theories and mechanisms of bioadhesion; bioadhesive polymers for drug delivery applications; methods for characterization of bioadhesiveness of drug delivery systems; bioadhesive films and drug delivery applications; bioadhesive nanoparticles; bioadhesive hydrogels and applications; ocular biodhesive drug delivery systems; buccal bioadhesive drug delivery systems; gastrointestinal bioadhesive drug delivery systems; nasal bioadhesive drug delivery systems; vaginal drug delivery systems; pulmonary bioadhesive drug delivery systems.
Book Synopsis Ocular Surface Disease: Cornea, Conjunctiva and Tear Film by : Edward J Holland
Download or read book Ocular Surface Disease: Cornea, Conjunctiva and Tear Film written by Edward J Holland and published by Elsevier Health Sciences. This book was released on 2013-05-17 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.
Book Synopsis Innovative Dosage Forms by : Yogeshwar Bachhav
Download or read book Innovative Dosage Forms written by Yogeshwar Bachhav and published by John Wiley & Sons. This book was released on 2019-12-04 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Teaches future and current drug developers the latest innovations in drug formulation design and optimization This highly accessible, practice-oriented book examines current approaches in the development of drug formulations for preclinical and clinical studies, including the use of functional excipients to enhance solubility and stability. It covers oral, intravenous, topical, and parenteral administration routes. The book also discusses safety aspects of drugs and excipients, as well as regulatory issues relevant to formulation. Innovative Dosage Forms: Design and Development at Early Stage starts with a look at the impact of the polymorphic form of drugs on the preformulation and formulation development. It then offers readers reliable strategies for the formulation development of poorly soluble drugs. The book also studies the role of reactive impurities from the excipients on the formulation shelf life; preclinical formulation assessment of new chemical entities; and regulatory aspects for formulation design. Other chapters cover innovative formulations for special indications, including oncology injectables, delayed release and depot formulations; accessing pharmacokinetics of various dosage forms; physical characterization techniques to assess amorphous nature; novel formulations for protein oral dosage; and more. -Provides information that is essential for the drug development effort -Presents the latest advances in the field and describes in detail innovative formulations, such as nanosuspensions, micelles, and cocrystals -Describes current approaches in early pre-formulation to achieve the best in vivo results -Addresses regulatory and safety aspects, which are key considerations for pharmaceutical companies -Includes case studies from recent drug development programs to illustrate the practical challenges of preformulation design Innovative Dosage Forms: Design and Development at Early Stage provides valuable benefits to interdisciplinary drug discovery teams working in industry and academia and will appeal to medicinal chemists, pharmaceutical chemists, and pharmacologists.
Book Synopsis Combination Drug Delivery Approach as an Effective Therapy for Various Diseases by : Prashant Kesharwani
Download or read book Combination Drug Delivery Approach as an Effective Therapy for Various Diseases written by Prashant Kesharwani and published by Academic Press. This book was released on 2022-03-27 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches. It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations. - Provides an accounting of vital aspects on various combination drug delivery approaches, presenting next generation diagnostics and therapeutics - Discusses the perspectives of current technologies in highly organized tables, illustrative figures and flow charts - Defines major gaps in knowledge that can lead to significant scientific discoveries
Book Synopsis Drug Delivery (book) by : Ashim K. Mitra
Download or read book Drug Delivery (book) written by Ashim K. Mitra and published by Jones & Bartlett Publishers. This book was released on 2014-08-08 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Delivery is the latest and most up-to-date text on drug delivery and offers an excellent working foundation for students and clinicians in health professions and graduate students including nursing, pharmacy, medicine, dentistry, as well as researchers and scientists. Presenting this complex content in an organized and concise format, Drug Delivery allows students to gain a strong understanding of the key concepts of drug delivery. This text focuses on the basic concepts of drug delivery while thoroughly examining various topics such as: CNS delivery Gene delivery Ocular delivery World-wide research on drug delivery Recent advances in drug delivery A significant advancement has been made in the field of drug delivery. This text provides a detailed overview of drug delivery systems, routes of drug administration and development of various formulations. The cutting edge research being carried out in this field will be compiled and a focus on worldwide research on drug delivery and targeting at the molecular, cellular, and organ levels will also be summarized. Each new print copy includes access to the Navigate Companion Website including: Chapter Quizzes, Interactive Glossary, Crossword Puzzles , Interactive Flashcards, and Matching Exercises
Book Synopsis Cutting-Edge Topics in Dry Eye Disease by : Kyung Chul Yoon
Download or read book Cutting-Edge Topics in Dry Eye Disease written by Kyung Chul Yoon and published by MDPI. This book was released on 2021-06-04 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents cutting-edge topics on and the diagnostic and therapeutic approaches for tear film abnormities, including dry eye disease and Meibomian gland dysfunction. A new management algorithm for Meibomian gland dysfunction, therapeutic eye drops and intense pulsed lasers for dry eye disease, and topical and systemic agents for neuropathic ocular pain are proposed in this issue.
Book Synopsis Ocular Therapeutics by : Thomas Yorio
Download or read book Ocular Therapeutics written by Thomas Yorio and published by Academic Press. This book was released on 2011-04-28 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States
Book Synopsis A Case-Based Guide to Eye Pain by : Michael S. Lee
Download or read book A Case-Based Guide to Eye Pain written by Michael S. Lee and published by Springer. This book was released on 2017-11-15 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing a patient with unexplained ocular pain can be time-consuming and difficult, but taking an anatomic approach and excluding causes along the way can aid in the diagnosis. This book provides the reader with a systematic evaluation plan for these cases, written and edited by leaders in the field. A Case-Based Guide to Eye Pain is written for both ophthalmologists and neuro-ophthalmologists since there are not enough neuro-ophthalmologists to treat the number of patients with unexplained ocular pain and general ophthalmologists are having to take on the diagnosis and treatment of these patients. Organized in an easy-to-use manner, each case covers the following key elements: the chief complaint, history of the present illness, the examination, assessment and plan, follow-up, alternate perspective, summary points, and key references. Tables are also available to help the reader rapidly sort through cases that may apply to a sign, symptom, historical feature, diagnostic test or treatment option. This allows the practitioner who has a patient with a particular concern to use the tables to identify a case discussion. Additionally, A Case-based Guide to Eye Pain includes an appendices with the general approach to eye pain and anatomy of the trigeminal pathway and its relation to eye pain.
Book Synopsis Treatment of Dry Eye by : Qingyan Zeng
Download or read book Treatment of Dry Eye written by Qingyan Zeng and published by World Scientific Publishing Company. This book was released on 2023-02-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dry eye is one of the most common ocular diseases. With the wide use of consumer electronics, environmental pollution and aging population, it has been prevalent and has seen a rising trend globally. Symptoms of dry eye affect daily activities and quality of life. This book details and illustrates popular medical science knowledge about dry eye. The cartoonist also shares her own treatment process. Various questions and doubts raised by dry eye patients and the effective therapy and treatment are well explained. The book provides a good resource for readers to acquire in-depth knowledge on causes and hazards brought about by dry eye as well as how to prevent its occurrence.
Book Synopsis Nanostructures for Drug Delivery by : Ecaterina Andronescu
Download or read book Nanostructures for Drug Delivery written by Ecaterina Andronescu and published by Elsevier. This book was released on 2017-03-24 with total page 1026 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. - Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems - Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area - Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial
Book Synopsis Mucoadhesive Materials and Drug Delivery Systems by : Vitaliy V. Khutoryanskiy
Download or read book Mucoadhesive Materials and Drug Delivery Systems written by Vitaliy V. Khutoryanskiy and published by John Wiley & Sons. This book was released on 2014-06-12 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucoadhesion defined as attachment of synthetic or natural materials to mucosal tissues has been widely exploited in pharmaceutical forms. This multi-author book provides an up-to-date account of current research on mucoadhesive materials and drug delivery systems. The introductory section describes the structure and physiology of various mucosal surfaces (oral, nasal, ocular, gastrointestinal and vaginal mucosa). This is followed by chapters on the various methods used to study mucoadhesion and to characterise mucoadhesive properties of various dosage forms. The final section will summarise information on traditional and novel types of mucoadhesive materials, such as chitosan, thiomers, and liposome-based formulations. This book is unique as there is currently no modern book considering mucoadhesion - all other existing books on the topic are either narrowly focused or more than 10 years old. Furthermore, each contributor offers specialist perspectives from a variety of global locations in both industrial and academic research centres.
Book Synopsis Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases by : Christopher L. Cioffi
Download or read book Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases written by Christopher L. Cioffi and published by Springer Nature. This book was released on 2020-09-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions, including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases. Retinal diseases are major contributors to moderate or severe vision impairment in adults aged 50 years and older. The respective patient populations for many of these indications is expected to significantly increase as the world population continues to grow older. An improved understanding of the etiological underpinnings of ocular degenerative diseases over the past decade has significantly bolstered ophthalmic drug discovery. In this volume, contributions from leading experts explore the unique challenges faced for ocular drug discovery and delivery providing the reader with detailed information on ocular pharmacokinetics, in vitro, ex vivo and in vivo models for retinal disease pathology and emerging gene therapy treatments. The book is intended for all researchers and clinicians who wish to increase their knowledge on the latest findings in ocular drug therapy.
