Novel diagnostic and therapeutic strategies in the management of cerebral gliomas

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832514634
Total Pages : 641 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel diagnostic and therapeutic strategies in the management of cerebral gliomas by : Valeria Barresi

Download or read book Novel diagnostic and therapeutic strategies in the management of cerebral gliomas written by Valeria Barresi and published by Frontiers Media SA. This book was released on 2023-02-14 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535110586
Total Pages : 656 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-04-10 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Diffuse Low-Grade Gliomas in Adults

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Author :
Publisher : Springer
ISBN 13 : 9781447122142
Total Pages : 502 pages
Book Rating : 4.1/5 (221 download)

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Book Synopsis Diffuse Low-Grade Gliomas in Adults by : Hugues Duffau

Download or read book Diffuse Low-Grade Gliomas in Adults written by Hugues Duffau and published by Springer. This book was released on 2013-04-16 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Diffuse Low-Grade Gliomas in Adults

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1447122135
Total Pages : 498 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Diffuse Low-Grade Gliomas in Adults by : Hugues Duffau

Download or read book Diffuse Low-Grade Gliomas in Adults written by Hugues Duffau and published by Springer Science & Business Media. This book was released on 2013-03-19 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research pertaining to the diagnosis, therapy and management of diffuse low-grade gliomas (DLGG) in adults, with a particular focus on the path towards individualised therapy for this kind of tumour. Recent research on the natural history of DLGGs and their interaction with the brain has led to new diagnostic and therapeutic strategies which increase survival and quality of life of the patient, and these methods are described in this book.

Gliomas

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Author :
Publisher : Academic Press
ISBN 13 : 0128030070
Total Pages : 464 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Gliomas by :

Download or read book Gliomas written by and published by Academic Press. This book was released on 2016-03-02 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers’ knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors. Gliomas reviews the current paradigms that underlie these fields, beginning with the molecular epidemiology of glioma susceptibility and prognosis through population-based science and genome-wide association studies. The book’s discussion of imaging modalities extends beyond advances in anatomical imaging to include metabolic and physiological studies. This work provides thorough discussion of the clinical view of tumors, ranging from the presentation of the patient to surgical management, and covers all therapeutic options for patient care, including chemotherapy, targeted molecular therapies, immunotherapies, and even personalized approaches to impact the set of lesions. Additionally, the book discusses radiotherapy with regard to the many options available to treat patients using myriad fractionated techniques with various sources. Finally, Gliomas reviews issues specific to the quality of life for patients, and techniques for maximizing the effect of caregivers. Edited and authored by premier researchers from around the world, Gliomas is a comprehensive reference for clinicians and researchers seeking the most up-to-date information on gliomas, and a guide to the best ways to effectively manage glioma patients and their care. Synthesizes widely dispersed information on the management of gliomas into one comprehensive resource Chapters written by international authors who are preeminent researchers in the field Fully explores the therapeutic options for patient care, from chemotherapy to radiotherapy to personalized approaches

Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789533075884
Total Pages : 434 pages
Book Rating : 4.0/5 (758 download)

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Book Synopsis Brain Tumors by : Ana Lucia Abujamra

Download or read book Brain Tumors written by Ana Lucia Abujamra and published by IntechOpen. This book was released on 2011-08-23 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumors: Current and Emerging Therapeutic Strategies focuses on tumor models, the molecular mechanisms involved in the pathogenesis of this disease, and on the new diagnostic and treatment strategies utilized to stage and treat this malignancy. A special section on immunotherapy and gene therapy provides the most up-to-date information on the pre-clinical and clinical advances of this therapeutic venue. Each chapter in Brain Tumors: Current and Emerging Therapeutic Strategies is authored by international experts with extensive experience in the areas covered.

New Therapeutic Strategies in Gliomas Treatment

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Author :
Publisher :
ISBN 13 : 9789533075884
Total Pages : pages
Book Rating : 4.0/5 (758 download)

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Book Synopsis New Therapeutic Strategies in Gliomas Treatment by : Gerardo Caruso

Download or read book New Therapeutic Strategies in Gliomas Treatment written by Gerardo Caruso and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Improving the Standard of Care in Glioblastoma

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Author :
Publisher :
ISBN 13 : 9789464231915
Total Pages : 167 pages
Book Rating : 4.2/5 (319 download)

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Book Synopsis Improving the Standard of Care in Glioblastoma by :

Download or read book Improving the Standard of Care in Glioblastoma written by and published by . This book was released on 2021 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on improving the standard of care for patients with glioblastoma, the most common and most aggressive primary brain tumor found in adults. Currently, patients with glioblastoma have a dismal prognosis due to the limited treatment options and their modest efficacy. In this thesis, the current standard of care for patients with newly diagnosed and recurrent glioblastoma was evaluated. We can conclude that the limited benefit from treatment options for patients with glioblastoma provokes the urgent need for novel treatment strategies to improve the quality of life and survival of these patients (chapter 2). Furthermore, MRI is still considered as the most optimal imaging modality for the evaluation of treatment response and effects in glioblastoma. However, the research in this thesis emphasizes the current challenges in the accurate assessment of treatment response and disease progression in these patients (chapter 3). We can, therefore, conclude that additional imaging techniques, including MR imaging features, can provide valuable information on tumor biology, tumor extent and tumor progression. In addition, the research presented in this thesis identified promising novel therapeutic targets (i.e. XIAP, RRM2 and MAPK9) and warrants further investigation (chapter 4). Furthermore, the STELLAR study is exploring an innovative treatment approach with high-dose, intermittent sunitinib in recurrent glioblastoma and is currently enrolling patients (chapter 5). Lastly, based on our systematic review, we concluded that, in its current state, immune checkpoint inhibitors demonstrate limited efficacy in patients with glioblastoma or brain metastases (chapter 6).

Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789533075884
Total Pages : 434 pages
Book Rating : 4.0/5 (758 download)

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Book Synopsis Brain Tumors by : Ana Lucia Abujamra

Download or read book Brain Tumors written by Ana Lucia Abujamra and published by IntechOpen. This book was released on 2011-08-23 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumors: Current and Emerging Therapeutic Strategies focuses on tumor models, the molecular mechanisms involved in the pathogenesis of this disease, and on the new diagnostic and treatment strategies utilized to stage and treat this malignancy. A special section on immunotherapy and gene therapy provides the most up-to-date information on the pre-clinical and clinical advances of this therapeutic venue. Each chapter in Brain Tumors: Current and Emerging Therapeutic Strategies is authored by international experts with extensive experience in the areas covered.

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

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Author :
Publisher : IntechOpen
ISBN 13 : 9789535110583
Total Pages : 654 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by IntechOpen. This book was released on 2013-04-10 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Glioblastoma:

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1441904107
Total Pages : 427 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Glioblastoma: by : Swapan K. Ray

Download or read book Glioblastoma: written by Swapan K. Ray and published by Springer Science & Business Media. This book was released on 2009-10-31 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.

Novel Treatment Strategies for Glioblastoma

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Author :
Publisher : Mdpi AG
ISBN 13 : 9783036525990
Total Pages : 282 pages
Book Rating : 4.5/5 (259 download)

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Book Synopsis Novel Treatment Strategies for Glioblastoma by : Stanley Stylli

Download or read book Novel Treatment Strategies for Glioblastoma written by Stanley Stylli and published by Mdpi AG. This book was released on 2021-12-21 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.

Intracranial Germ Cell Tumors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 370916821X
Total Pages : 462 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Intracranial Germ Cell Tumors by : Yutaka Sawamura

Download or read book Intracranial Germ Cell Tumors written by Yutaka Sawamura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients. This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries.

Diseases of the Brain, Head and Neck, Spine 2020–2023

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Author :
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Pediatric CNS Tumors

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662092271
Total Pages : 373 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Pediatric CNS Tumors by : Nalin Gupta

Download or read book Pediatric CNS Tumors written by Nalin Gupta and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Oncology - Pediatric CNS Tumors is a detailed review of childhood nervous system tumors with a particular emphasis on biological data and treatment algorithms for each tumor type. Additional detailed information is provided on the recent advances in chemotherapy, radiation and surgery for these tumors. All brain tumors discussed in detail by pathological type Current therapeutic strategies for pediatric brain tumors Includes surgery, chemotherapy, and radiation therapy

The Duke Glioma Handbook

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1107065976
Total Pages : 237 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis The Duke Glioma Handbook by : Allan H. Friedman

Download or read book The Duke Glioma Handbook written by Allan H. Friedman and published by Cambridge University Press. This book was released on 2016-03-31 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

High-Grade Gliomas

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1597451851
Total Pages : 493 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis High-Grade Gliomas by : Gene H. Barnett

Download or read book High-Grade Gliomas written by Gene H. Barnett and published by Springer Science & Business Media. This book was released on 2007-11-21 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is truly an exciting time in the field of neuro-oncology, particularly in the area of hi- grade gliomas. The management of patients with high-grade gliomas has historically been one of the most challenging and disheartening fields in medicine, where failure is the rule and longevity is the exception. The jaded often state that despite purported advances in surgical and radiotherapeutic techniques and a myriad of clinical trials of medical therapies, the s- vival statistics for glioblastoma have not changed in the last three decades. The nihilism associated with these tumors is such that some practitioners still advise against treatment or even biopsy, recommending palliative care with the diagnosis based only on history and an MRI scan. If the current state-of-the-art in the diagnosis and management of high-grade gliomas was truly so bleak, there would be no reason to compile and publish a monograph on the subject. The fact is that we have recently entered an era where real progress is being made in our understanding and treatment of high-grade gliomas that is directly benefiting some patients. We are slowly but surely chipping away at this problem. One approach has exploited correlations between particular molecular markers and therapeutic response. The first such “breakthrough” in high-grade glioma was the observation that loss of chromosomes 1p and 19q uniformly predict chemosensitivity in anaplastic oligodendrogliomas (1).