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Novel Approaches For Single Molecule Activation And Detection
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Book Synopsis Novel Approaches for Single Molecule Activation and Detection by : Fabio Benfenati
Download or read book Novel Approaches for Single Molecule Activation and Detection written by Fabio Benfenati and published by Springer. This book was released on 2014-06-26 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can we obtain tools able to process and exchange information at the molecular scale? In order to do this, it is necessary to activate and detect single molecules under controlled conditions. This book focuses on the generation of biologically-inspired molecular devices. These devices are based on the developments of new photonic tools able to activate and stimulate single molecule machines. Additionally, new light sensitive molecules can be selectively activated by photonic tools. These technological innovations will provide a way to control activation of single light-sensitive molecules, allowing the investigation of molecular computation in a biological environment.
Book Synopsis New Techniques in Systems Neuroscience by : Adam D. Douglass
Download or read book New Techniques in Systems Neuroscience written by Adam D. Douglass and published by Springer. This book was released on 2015-04-13 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is essential reading for anyone wishing to understand the recent explosion of experimental tools in neuroscience that now make it possible to manipulate, record, and understand neuronal activity within the intact brain, and which are helping us learn how the many neurons that comprise a network act together to control behavior. Leaders in the field discuss the latest developments in optogenetics, functional imaging, circuit mapping, and the application of these tools to complex biological problems.
Book Synopsis Super-Resolution Imaging in Biomedicine by : Alberto Diaspro
Download or read book Super-Resolution Imaging in Biomedicine written by Alberto Diaspro and published by CRC Press. This book was released on 2016-11-03 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book encompasses the full breadth of the super-resolution imaging field, representing modern techniques that exceed the traditional diffraction limit, thereby opening up new applications in biomedicine. It shows readers how to use the new tools to increase resolution in sub-nanometer-scale images of living cells and tissue, which leads to new information about molecules, pathways and dynamics. The book highlights the advantages and disadvantages of the techniques, and gives state-of-the-art examples of applications using microscopes currently available on the market. It covers key techniques such as stimulated emission depletion (STED), structured illumination microscopy (SSIM), photoactivated localization microscopy (PALM), and stochastic optical reconstruction microscopy (STORM). It will be a useful reference for biomedical researchers who want to work with super-resolution imaging, learn the proper technique for their application, and simultaneously obtain a solid footing in other techniques.
Book Synopsis All-Optical Methods to Study Neuronal Function by : Eirini Papagiakoumou
Download or read book All-Optical Methods to Study Neuronal Function written by Eirini Papagiakoumou and published by Springer Nature. This book was released on 2023-02-20 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume provides an overview of the latest methods used to study neuronal function with all-optical experimental approaches, where light is used for both stimulation and monitoring of neuronal activity. The chapters in this book cover topics over a broad range, from fundamental background information in both physiology and optics in the context of all-optical neurophysiology experiments, to the design principles and hardware implementation of optical methods used for photoactivation and imaging. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, All-Optical Methods to Study Neuronal Function is a valuable resource for researchers in various disciplines such as physics, engineering, and neuroscience. This book will serve as a guide to establish useful references for groups starting out in this field, and provide insight on the optical systems, actuators, and sensors. This is an open access book.
Book Synopsis Quick Reference NeuroScience for Rehabilitation Professionals by : Sharon A. Gutman
Download or read book Quick Reference NeuroScience for Rehabilitation Professionals written by Sharon A. Gutman and published by Taylor & Francis. This book was released on 2024-06-01 with total page 771 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Quick Reference NeuroScience for Rehabilitation Professionals: The Essential Neurologic Principles Underlying Rehabilitation Practice, Third Edition" is a user-friendly, comprehensive text that specifically addresses the key information needed to understand the neuroscience of clinical rehabilitation. A concise and quick reference for the practitioner and student who are learning or reviewing the most relevant neuroscience principles supporting rehabilitation therapy. The updated third edition continues to meet a need in the rehabilitation profession that has gone unfilled - the ability to break down neuroscience information into the essential principles that can be used to understand neurological conditions and the principles underlying rehabilitation evaluation and practice. This fully-updated third edition provides a quick review of specific neuroscience concepts and principles that support rehabilitation interventions. In this era of information overload, this text rapidly and thoroughly provides condensed information in a user-friendly, easy-to-use format for readers to review and convey relevant information to patients. Sharon Gutman has organised the text into three parts: the first addresses neuroanatomy; the second addresses the function of neurological systems underlying physical, psychiatric, cognitive, and visual perceptual disorders; and the final section addresses clinical neuropathology related to ageing, addiction, memory, and the neurological substrates of sex and gender. A specific section describes the common neurodiagnostic tests that therapists do not administer but must have knowledge of when results are discussed at treatment team meetings. Features of the third edition: Presented in a simple and organised bulleted format. Large-scale colour illustrations to easily visualise neuroanatomical structures and systems. Text boxes to apply key neuroscience concepts to the understanding of common neurological disorders and treatment. Updated clinical test questions and glossary. The third edition bridges a gap by quickly providing the rehabilitation professional with the most salient information needed to understand neurologic principles underlying rehabilitation practice.
Book Synopsis Novel Tools and Strategies of Nanopore Single-molecule Biosensing by : Ren Ren
Download or read book Novel Tools and Strategies of Nanopore Single-molecule Biosensing written by Ren Ren and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Pharmacology by : John Dickenson
Download or read book Molecular Pharmacology written by John Dickenson and published by John Wiley & Sons. This book was released on 2012-11-30 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
Book Synopsis Gangliosides in Health and Disease by :
Download or read book Gangliosides in Health and Disease written by and published by Academic Press. This book was released on 2018-04-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings together world experts in ganglioside structure and function who have been assembled to contribute to this thorough update of the field. Contains accessible content that is ideal for students and researchers alike Written by leading authorities in the field
Book Synopsis Combining Single Molecule and Bulk Phase Approaches to Investigate Damage Detection by Nucleotide Excision Repair Proteins by : Jamie Barnett
Download or read book Combining Single Molecule and Bulk Phase Approaches to Investigate Damage Detection by Nucleotide Excision Repair Proteins written by Jamie Barnett and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Towards translating research to clinical practice: Novel Strategies for Discovery and Validation of Biomarkers for Brain Injury by : Stefania Mondello
Download or read book Towards translating research to clinical practice: Novel Strategies for Discovery and Validation of Biomarkers for Brain Injury written by Stefania Mondello and published by Frontiers Media SA. This book was released on 2015-02-25 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) is a major cause of death and disability and one of the greatest unmet needs in medicine and public health. TBI not only has devastating effects on patients and their relatives but results in huge direct and indirect costs to society. Although guidelines for the management of patients have been developed and more than 200 clinical trials have been conducted, they have resulted in few improvements in clinical outcomes and no effective therapies approved for TBI. It is now apparent that the heterogeneity of clinical TBI is underlain by molecular phenotypes more complex and interactive than initially conceived and current approaches to the characterization, management and outcome prediction of TBI are antiquated, unidimensional and inadequate to capture the interindividual pathophysiological heterogeneity. Recent advances in proteomics and biomarker development provide unparalleled opportunities for unraveling substantial injury-specific and patient-specific variability and refining disease characterization. The identification of novel, sensitive, objective tools, referred to as biomarkers, can revolutionize pathophysiological insights, enable targeted therapies and personalized approaches to clinical management. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. Finally, suggestions are provided for the way forward, with an emphasis on need for a multidimensional approach that integrate a panel of pathobiologically diverse biomarkers with clinical variables and imaging-based assessments to improve diagnosis and classification of TBI and to develop best clinical practice guidelines.
Book Synopsis Novel strategies to repair the infarcted heart by : Anke Smits
Download or read book Novel strategies to repair the infarcted heart written by Anke Smits and published by Frontiers Media SA. This book was released on 2023-01-05 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Novel Approaches and Their Applications in Risk Assessment by : Yuzhou Luo
Download or read book Novel Approaches and Their Applications in Risk Assessment written by Yuzhou Luo and published by BoD – Books on Demand. This book was released on 2012-04-20 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment is a critical component in the evaluation and protection of natural or anthropogenic systems. Conventionally, risk assessment is involved with some essential steps such as the identification of problem, risk evaluation, and assessment review. Other novel approaches are also discussed in the book chapters. This book is compiled to communicate the latest information on risk assessment approaches and their effectiveness. Presented materials cover subjects from environmental quality to human health protection.
Book Synopsis High Content Screening by : Steven A. Haney
Download or read book High Content Screening written by Steven A. Haney and published by John Wiley & Sons. This book was released on 2008-01-18 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authoritative reference on High Content Screening (HCS) in biological and pharmaceutical research, this guide covers: the basics of HCS: examples of HCS used in biological applications and early drug discovery, emphasizing oncology and neuroscience; the use of HCS across the drug development pipeline; and data management, data analysis, and systems biology, with guidelines for using large datasets. With an accompanying CD-ROM, this is the premier reference on HCS for researchers, lab managers, and graduate students.
Book Synopsis Single Molecule Detection in Solution by : LiQiang Li
Download or read book Single Molecule Detection in Solution written by LiQiang Li and published by . This book was released on 1994 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors by :
Download or read book Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors written by and published by Academic Press. This book was released on 2020-01-16 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scienti?c importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine ß-synthase, and Oligomerization of Porphobilinogen Synthase. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field of molecular biology
Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2023-03-13 with total page 9295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die neueste Ausgabe des Goldstandards in der Krebsforschung und klinischen Onkologie Mit der neu überarbeiteten zehnten Ausgabe von Holland-Frei Cancer Medicine legt ein Team anerkannter Forscher und Ärzte einen umfassenden aktuellen Überblick über die Krebsforschung und die klinische onkologische Praxis vor. Das Werk enthält zeitgemäße und unverzichtbare Informationen aus den Bereichen Epidemiologie, Ätiologie, Krebsbiologie, Immunologie, Prävention, Screening, klinisches Erscheinungsbild, Pathologie, Bildgebung und Therapie. Ausgehend von einem grundlegenden Verständnis der Krebsbiologie stellt Holland-Frei Cancer Medicine eine Verbindung zwischen wissenschaftlichen Prinzipien und klinischer Praxis her. Das Buch enthält Hunderte farbiger Abbildungen und Fotos, Tabellen, Grafiken und Algorithmen, um die im Text erörterten komplexen Inhalte zu ergänzen und zu vertiefen. Das unverzichtbare klinische Lehrbuch ist darauf ausgelegt, die Inhalte mit separaten Zusammenfassungen, zusätzlichen Verweisen und anderen pädagogischen Merkmalen übersichtlich und leicht verständlich zu präsentieren. Außerdem bietet das Werk: * Einen integrierten translationalen Ansatz, der die Krebsbiologie mit dem Krebsmanagement verbindet * Einen starken Fokus auf die multidisziplinäre, forschungsorientierte Patientenversorgung, wodurch bessere Ergebnisse erzielt und der optimale Einsatz aller klinisch geeigneten Therapien ermöglicht werden sollen * Eine Erörterung des neuesten Trends der personalisierten Krebsbehandlung mit molekularer Diagnostik und Therapeutik Die zehnte Auflage von Holland-Frei Cancer Medicine richtet sich nicht nur an medizinische Onkologen, Strahlenonkologen und Internisten, sondern hat auch einen Platz in den Bibliotheken anderer Gesundheitsfachkräfte verdient, die sich mit der Behandlung von Krebspatienten beschäftigen. Dieses Werk wird in Zusammenarbeit mit der American Association for Cancer Research herausgegeben: https://www.aacr.org/
Book Synopsis Medical Biosensors for Point of Care (POC) Applications by : Roger Narayan
Download or read book Medical Biosensors for Point of Care (POC) Applications written by Roger Narayan and published by Woodhead Publishing. This book was released on 2016-08-21 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications Includes contributions from leading international researchers with extensive experience in developing medical biosensors Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care
