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Book Synopsis The Proteomics Protocols Handbook by : John M. Walker
Download or read book The Proteomics Protocols Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2007-10-09 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on researchers describe in step-by-step detail 73 proven laboratory methods and bioinformatics tools essential for analysis of the proteome. These cutting-edge techniques address such important tasks as sample preparation, 2D-PAGE, gel staining, mass spectrometry, and post-translational modification. There are also readily reproducible methods for protein expression profiling, identifying protein-protein interactions, and protein chip technology, as well as a range of newly developed methodologies for determining the structure and function of a protein. The bioinformatics tools include those for analyzing 2D-GEL patterns, protein modeling, and protein identification. All laboratory-based protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Book Synopsis Cell Biology Assays by : Fanny Jaulin
Download or read book Cell Biology Assays written by Fanny Jaulin and published by Academic Press. This book was released on 2009-11-23 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein assay methods are used for protein identification with blood groups, cell surface markers, drugs and toxins. This text features comprehensive protocols essential for researchers studying various areas of biological and medical sciences. The techniques in this text are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls while enabling researchers at all stages to embark on basic problems using a vareity of technologies and model systems. Focus on protein identification using mass spectrometry Step-by-step procedures detailing materials, procedures, comment and pitfalls Information on the plethora of technologies needed to tackle complex problems
Download or read book Federal Register written by and published by . This book was released on 2013-10 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Protein Sequencing Protocols by : Bryan John Smith
Download or read book Protein Sequencing Protocols written by Bryan John Smith and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Determination of the protein sequence is as important today as it was a half century ago, even though the techniques and purposes have changed over time. Mass spectrometry has continued its recent rapid development to find notable application in the characterization of small amounts of protein, for example, in the field of proteomics. The “traditional” chemical N-terminal sequencing is still of great value in quality assurance of the increasing number of biopharmaceuticals that are to be found in the clinic, checking processing events of recombinant proteins, and so on. It is joined in the armory of me- ods of protein analysis by such techniques as C-terminal sequencing and amino acid analysis. These methods are continually developing. The first edition of Protein Sequencing Protocols was a “snapshot” of methods in use in protein biochemistry laboratories at the time, and this, the second edition, is likewise. Methods have evolved in the intervening period, and the content of this book has similarly changed, the content of some chapters having been superceded and replaced by other approaches. Thus, in this edition, there is inclusion of approaches to validation of methods for quality assurance work, reflecting the current importance of biopharmaceuticals, and also a guide to further analysis of protein sequence information, acknowledging the importance of bioinformatics.
Book Synopsis Physical Medicine and Rehabilitation Board Review, Third Edition by : Sara J Cuccurullo, MD
Download or read book Physical Medicine and Rehabilitation Board Review, Third Edition written by Sara J Cuccurullo, MD and published by Demos Medical Publishing. This book was released on 2014-11-25 with total page 1053 pages. Available in PDF, EPUB and Kindle. Book excerpt: Doody's Core Title 2013! "This book does an excellent job and is currently the only known review book for physiatrists. The author has done it again, producing an excellent, concise resource that provides clinicians with an optimal solution for studying for the written board examination." --Doodys Reviews This third edition of the incomparable review bible for the Physical Medicine and Rehabilitation Board Examination has been completely updated to reflect current practice and the core knowledge tested on the exam. Known for its organization, consistency, and clarity, the book distills the essentials and provides focused reviews of all major topics. Coverage is expanded in the third edition to include dedicated sections on pain management, medical ethics, and ultrasound that reflect new board requirements. Written in outline format for readability and easy access to information, content is modeled after the topic selection of the AAPMR Self-Directed Medical Knowledge Program used by residents nationwide. To aid in information retention, ìPearlsî are designated with an open-book icon to highlight key concepts and stress clinical and board-eligible aspects of each topic. The text is divided into major subspecialty areas written by authors with clinical expertise in each subject area, and content is reviewed by senior specialists to ensure the utmost accuracy. More than 500 high-quality illustrations clarify and reinforce concepts. The book also provides updated epidemiologic and statistical data throughout and includes a section on biostatistics in physical medicine and rehabilitation. In addition to its proven value as a resource for exam preparation, the book is also a must-have for practicing physiatrists seeking recertification, and for PM&R instructors helping trainees to prepare for the exam. New to the Third Edition: Thoroughly reviewed, revised, and updated to reflect current practice and core knowledge tested on Boards Improved organization, clarity, and consistency Presents new chapters/sections on pain management, medical ethics, and ultrasound Key Features: Board"Pearlsî are highlighted with an open-book icon throughout the text to flag key concepts and stress high-yield aspects of each topic Models the table of contents after the topic selection of the AAPMR Self-Directed Medical Knowledge Program used by residents nationwide Authored by physicians with special interest and clinical expertise in their respective areas and reviewed by senior specialists in those areas Organizes information in outline format and by topic for easy reference Includes over 500 illustrations to clarify concepts Provides updated epidemiologic and statistical data throughout Contains a section on biostatistics in physical medicine & rehabilitation Praise for the First Edition: ì... there is no other comparable text in PM&R. The key resource for facts needed to pass boards and useful for those in clinical practice for day to day use as well. - -Doody's Reviews "I congratulate the editors and authors for coming up with such incredible and concise work...I think that this book is a must for all residents undergoing training in the field of Physical Medicine and Rehabilitation." -Saudi Medical Journal "Over the years many residents have confronted the problem of what to study for the boards...This elegant volume will finally fulfill this critical void" - From the foreword by Ernest W. Johnson, M.D.
Book Synopsis SEC Docket by : United States. Securities and Exchange Commission
Download or read book SEC Docket written by United States. Securities and Exchange Commission and published by . This book was released on 2012 with total page 1270 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book FEDLINK Technical Notes written by and published by . This book was released on 1993 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bacterial Pathogenesis by : Frank R. DeLeo
Download or read book Bacterial Pathogenesis written by Frank R. DeLeo and published by Springer Science & Business Media. This book was released on 2008-01-31 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial infections affect world health today as a leading cause of morbidity and mortality. This book presents in-depth methods and state-of-the-art protocols for investigating specific mechanisms of pathogenesis for a wide range of bacteria. Written by experts in the field, this invaluable collection includes protocols to study host-pathogen interactions, animal models of infection, and novel approaches to identifying therapeutic targets designed to control infections.
Book Synopsis Breast Cancer Research Protocols by : Susan A. Brooks
Download or read book Breast Cancer Research Protocols written by Susan A. Brooks and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of both well-established and cutting-edge methods for investigating breast cancer biology not only in the laboratory, but also in clinical settings. These readily reproducible techniques solve a variety of problems, ranging from how to collect, store, and prepare human breast tumor samples for analysis, to analyzing cells in vivo and in vitro. Additional chapters address the technology of handling biopsies, new methods for analyzing genes and gene expression, markers of clinical outcome and progress, analysis of tumor-derived proteins and antigens, validating targets, and investigating the biology of newly discovered genes.
Book Synopsis Proteome Research: Two-Dimensional Gel Electrophoresis and Identification Methods by : T. Rabilloud
Download or read book Proteome Research: Two-Dimensional Gel Electrophoresis and Identification Methods written by T. Rabilloud and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the end of the Human Genome Project in sight, the next important step is to determine the function of genes. Proteome Research is an important approach to this study and is the first book to comprehensively cover the application of two-dimensional electrophoresis, the central methodology in proteome research. The state-of-the-art is described in detail and the available detection methods are extensively covered. Sufficient detail is given to allow readers to apply these technologies to their own particular requirements.
Book Synopsis New and Emerging Proteomic Techniques by : Dobrin Nedelkov
Download or read book New and Emerging Proteomic Techniques written by Dobrin Nedelkov and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers and innovators describe in step-by-step detail the latest techniques that promise to significantly impact the practice of proteomics, as well as its success in developing novel clinical agents. The methods span the entire spectrum of top-down and bottom-up approaches, including microarrays, gels, chromatography, and affinity separations, and address every aspect of the human proteome, both quantitatively and qualitatively. The techniques of protein detection utilized are diverse and range from fluorescence and resonance light scattering to surface plasmon resonance and mass spectrometry. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Book Synopsis Arabidopsis Protocols, 2nd Edition by : Julio Salinas
Download or read book Arabidopsis Protocols, 2nd Edition written by Julio Salinas and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: For several decades, Arabidopsis thaliana has been the organism of choice in the laboratories of many plant geneticists, physiologists, developmental biologists, and biochemists around the world. During this time, a huge amount of knowledge has been acquired on the biology of this plant species, which has resulted in the development of molecular tools that account for much more efficient research. The significance that Arabidopsis would attain in biological research may have been difficult to foresee in the 1980s, when its use in the laboratory started. In the meantime, it has become the model plant organism, much the same way as Drosophila, Caenorhabditis, or mouse have for animal systems. Today, it is difficult to envision research at the cutting edge of plant biology without the use of Arabidopsis. Since the first edition of Arabidopsis Protocols appeared, new developments have fostered an impressive advance in plant biology that prompted us to prepare Arabidopsis Protocols, Second Edition. Completion of the Arabidopsis genome sequence offered for the first time the opportunity to have in hand all of the genetic information required for studying plant function. In addition, the development of whole systems approaches that allow global analysis of gene expression and protein and metabolite dynamics has encouraged scientists to explore new scenarios that are extending the limits of our knowledge.
Book Synopsis Clinical Proteomics by : Antonia Vlahou
Download or read book Clinical Proteomics written by Antonia Vlahou and published by Springer Science & Business Media. This book was released on 2008-01-18 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a select group of researchers has contributed their state-of-the-art methodologies on protein profiling and identification of disease biomarkers in tissues, microdissected cells and body fluids. The book integrates biochemistry, pathology, analytical technology, bioinformatics, and proteome informatics. Experimental approaches are thoroughly detailed and explained through a step-by-step instructional format that ensures successful results.
Book Synopsis Molecular Diagnosis of Infectious Diseases by : Jochen Decker
Download or read book Molecular Diagnosis of Infectious Diseases written by Jochen Decker and published by Springer Science & Business Media. This book was released on 2008-02-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Populations of the western world are now healthier and enjoying higher life expectancy than ever. They are beginning to benefit from an array of costly new therapies made possible through recent rapid advances in medical science and technology, and their demands on modern medicine are rising. Meanwhile, healthcare systems are struggling with their outdated legacy models of the m- th 20 century and are experiencing ever-increasing financial pressure from g- ernments and health insurance organizations. The equation is no longer in balance, and this predicament is forcing societies to explore new approaches to managing healthcare in the future. Since the first edition of Molecular Diagnosis of Infectious Diseases was published, we have witnessed the sequencing of the (almost) complete human genome and a shift in medical research from an emphasis on genetics to the advancement and useful application of proteomics. Bioinformatics has become the key tool for managing and analyzing the upsurge of data, and faster and more effective test methods and technologies have opened up new prospects for ind- try and academia. The tools of modern genomics and proteomics are now being utilized to specifically guide the discovery of drugs for the prevention, diagnosis, and treatment of human disease. They may also help us to find a way out of the current healthcare calamity.
Book Synopsis Plant Functional Genomics by : Fatemeh Maghuly
Download or read book Plant Functional Genomics written by Fatemeh Maghuly and published by Springer Nature. This book was released on with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Systematic Innovation Partnerships with Artificial Intelligence and Information Technology by : Robert Nowak
Download or read book Systematic Innovation Partnerships with Artificial Intelligence and Information Technology written by Robert Nowak and published by Springer Nature. This book was released on 2022-09-23 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 22nd International TRIZ Future Conference on Automated Invention for Smart Industries, TFC 2022, which took place in Warsaw, Poland, in September 2022; the event was sponsored by IFIP WG 5.4.The 39 full papers presented were carefully reviewed and selected from 43 submissions. They are organized in the following thematic sections: New perspectives of TRIZ; AI in systematic innovation; systematic innovations supporting IT and AI; TRIZ applications; TRIZ education and ecosystem.
Book Synopsis Proteomic Methods in Neuropsychiatric Research by : Paul C. Guest
Download or read book Proteomic Methods in Neuropsychiatric Research written by Paul C. Guest and published by Springer. This book was released on 2017-03-28 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
