Nitroglycerin 9

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110809176
Total Pages : 136 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Nitroglycerin 9 by : Thomas Meinertz

Download or read book Nitroglycerin 9 written by Thomas Meinertz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 9".

Organic Nitrates

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 364266024X
Total Pages : 206 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Organic Nitrates by : P. Needleman

Download or read book Organic Nitrates written by P. Needleman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.

National Drug Code Directory

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Author :
Publisher :
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis National Drug Code Directory by :

Download or read book National Drug Code Directory written by and published by . This book was released on 1985 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nitroglycerine and Nitroglycerine Explosives

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Author :
Publisher :
ISBN 13 :
Total Pages : 524 pages
Book Rating : 4.:/5 (7 download)

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Book Synopsis Nitroglycerine and Nitroglycerine Explosives by : Phokion P. Naoúm

Download or read book Nitroglycerine and Nitroglycerine Explosives written by Phokion P. Naoúm and published by . This book was released on 1928 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Military Explosives

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Publisher :
ISBN 13 :
Total Pages : 400 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Military Explosives by :

Download or read book Military Explosives written by and published by . This book was released on 1989 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nitroglycerin 7

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110870568
Total Pages : 108 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Nitroglycerin 7 by : P. G. Hugenholtz

Download or read book Nitroglycerin 7 written by P. G. Hugenholtz and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-08 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Nitroglycerin 7".

Nitrates III

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Publisher : Springer Science & Business Media
ISBN 13 : 3642680852
Total Pages : 713 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Nitrates III by : P. Lichtlen

Download or read book Nitrates III written by P. Lichtlen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological and clinical research on nitrates continues to be of growing interest in many centers. This is surprising in view of the fact that their favorable effects in angina pectoris were described by Brunton and by Murrell in the Lancet more than 100 years ago. As expected, a host of new information has been collected since the two previous symposia on nitrates held in Stockholm in 1975 and Berlin in 1978. New insights were gained into the pharmacology, pharmacokinetics and pharmacodynamics of nitrates, as well as into their clinical effects in acute and chronic ischemic heart diseases and in severe congestive heart failure. Relatively little progress, however, was observed in research into the basic action of nitrates. Although most investigators agree that intracellular sequestration of calcium is probably the main mechanism by which nitrates lead to the reduction of vascular smooth muscle tone, the exact site of their action still remains undefined. In contrast, dose-dependent differences in venous and arteriolar tone have long been clearly established. Treatment was again in the main stream of discussion. The question of tolerance following long-term administration was discussed in depth and the term "pseudotolerance" was introduced to describe the adaptation of the body's circulatory system to chronic vasodilation. This is especially important in long term prophylactic antiischemic treatment in stable, as well as in unstable angina pectoris (i.e. during increased vasomotor tone - spasm).

Emergency Response Guidebook

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1626363765
Total Pages : 400 pages
Book Rating : 4.6/5 (263 download)

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Book Synopsis Emergency Response Guidebook by : U.S. Department of Transportation

Download or read book Emergency Response Guidebook written by U.S. Department of Transportation and published by Simon and Schuster. This book was released on 2013-06-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.

Pharmacotherapy A Pathophysiologic Approach 9/E

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Publisher : McGraw Hill Professional
ISBN 13 : 0071800549
Total Pages : 2629 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Pharmacotherapy A Pathophysiologic Approach 9/E by : Joseph T. DiPiro

Download or read book Pharmacotherapy A Pathophysiologic Approach 9/E written by Joseph T. DiPiro and published by McGraw Hill Professional. This book was released on 2014-03-22 with total page 2629 pages. Available in PDF, EPUB and Kindle. Book excerpt: 25 ADDITIONAL CHAPTERS AVAILABLE ONLINE THE LANDMARK TEXT ON HOW TO ACHIEVE OPTIMAL PATIENT OUTCOMES THROUGH EVIDENCE-BASED MEDICATION THERAPY Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers. NEW TO THIS EDITION: A section on personalized pharmacotherapy appears in most sections All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches have been updated in full color to clearly distinguish treatment pathways New drug monitoring tables have been added Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that often include ratings of the level of evidence to support the key therapeutic approaches Twenty-five online-only chapters are available at www.pharmacotherapyonline.com

Nitroglycerin Sustained Release Tablet. Formulation Design and Evaluation

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Author :
Publisher : GRIN Verlag
ISBN 13 : 3656475849
Total Pages : 135 pages
Book Rating : 4.6/5 (564 download)

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Book Synopsis Nitroglycerin Sustained Release Tablet. Formulation Design and Evaluation by : Subrata Bhadra

Download or read book Nitroglycerin Sustained Release Tablet. Formulation Design and Evaluation written by Subrata Bhadra and published by GRIN Verlag. This book was released on 2013-08-07 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2010 in the subject Medicine - Pharmacology, Pharmacy, University of Dhaka (M. Pharm, in Pharmaceutical Technology), language: English, abstract: The aim of the present studies was to develop and characterize 2.6 mg sustained release matrix tablets of Nitroglycerin. Tablets were prepared by direct compression method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in nine formulations (F-1 to F-9). The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, Carr’s index, Hausner ratio, moisture content, total porosity and assay. The tablets were subjected to diameter, thickness, assay, uniformity of content, assay after 1Month at 40°C+75%RH, hardness, friability, and in vitro dissolution studies. The granules showed satisfactory flow properties, compressibility, and drug content. All the tablet formulations showed acceptable pharmacotechnical properties and complied with pharmacopoeial specifications for tested parameters. The in vitro dissolution study was carried out for 8 hour using USP-2009 Apparatus-I (Rotating basket method) in distilled water as the dissolution medium. The release mechanisms were explored and explained by Zero order, First order, Higuchi, Korsmeyer-Peppas and Hixson-Crowell equations. Nine formulations were prepared by using three variable ratio of two polymers; Methocel K15M CR (25%, 20% and 15%) and Methocel K100LV CR (15%, 10% and 5%) where all the formulations (F-1 to F-9) contained 0.5% colloidal silicon dioxide and 1% magnesium stearate. Among these nine formulations, six formulations; F-2 (Methocel K15M CR: Methocel K100LV CR = 25% : 10%), F-3 (Methocel K15M CR : Methocel K100LV CR = 25% : 5%), F-4 (Methocel K15M CR : Methocel K100LV CR = 20% : 15%) F-5 (Methocel K15M CR: Methocel K100LV CR = 20% : 10%), F-6 (Methocel K15M CR : Methocel K100LV CR = 20% : 5%) and F-7 (Methocel K15M CR : Methocel K100LV CR = 15% : 15%) met the official specification of release profile. It was also found that the type and the amount of polymers significantly affect the time required for 50% (T50% or MDT) of drug release, release rate constant and diffusion exponent. Higher the MDT value indicates a higher drug retaining capacity of the polymers and vice-versa. Kinetic modeling of in vitro dissolution profiles revealed the drug release mechanism of all proposed formulations followed anomalous type or non-Fickian transport (n>0.43 and n

Chemicals Identified in Human Biological Media

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Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chemicals Identified in Human Biological Media by :

Download or read book Chemicals Identified in Human Biological Media written by and published by . This book was released on 1981 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A symposium

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Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.:/5 (268 download)

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Book Synopsis A symposium by :

Download or read book A symposium written by and published by . This book was released on 1992 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1828 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index-catalogue of the Library of the Surgeon-General's Office, United States Army

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Publisher :
ISBN 13 :
Total Pages : 874 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis Index-catalogue of the Library of the Surgeon-General's Office, United States Army by : National Library of Medicine (U.S.)

Download or read book Index-catalogue of the Library of the Surgeon-General's Office, United States Army written by National Library of Medicine (U.S.) and published by . This book was released on 1906 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Opening the East River

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Publisher : McFarland
ISBN 13 : 1476682984
Total Pages : 237 pages
Book Rating : 4.4/5 (766 download)

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Book Synopsis Opening the East River by : Thomas Barthel

Download or read book Opening the East River written by Thomas Barthel and published by McFarland. This book was released on 2021-08-31 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the Civil War, the New York City's East River was a massive unsolved and dangerous navigation problem. A major waterway into and out of the Harbor--where customs revenue equaled 42 percent of the U.S. Government's income--the river's many hindrances, centered around Hell Gate, included whirlpools, rocks and reefs. These, combined with swirling currents and powerful tides, led to deaths, cargo losses and destruction of vessels. Charged with clearing the river, General John Newton of the Army Corps of Engineers went to work with the most rudimentary tools for diving, mining, lighting, pumping and drilling. His crews worked for 20 years, using a steam-drilling scow of his own design and a new and perilous explosive--nitroglycerine. In 1885, Newton destroyed the nine-acre Flood Rock with 282,730 pounds of high explosives. The demolition was watched by tens of thousands. This book chronicles the clearing of the East River and the ingenuity of the Army engineer whose work was praised by the National Academy of Sciences.

Profiles of Drug Substances, Excipients and Related Methodology

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Author :
Publisher : Elsevier
ISBN 13 : 9780080522630
Total Pages : 334 pages
Book Rating : 4.5/5 (226 download)

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Book Synopsis Profiles of Drug Substances, Excipients and Related Methodology by :

Download or read book Profiles of Drug Substances, Excipients and Related Methodology written by and published by Elsevier. This book was released on 2003-12-19 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodologoy related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. - Presents comprehensive reviews covering all aspects of drug development and formulation of drugs - Now encompassing critical review chapters - Meets the information needs of the drug development community

Analytical Profiles of Drug Substances and Excipients

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Author :
Publisher : Academic Press
ISBN 13 : 0080861156
Total Pages : 783 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Analytical Profiles of Drug Substances and Excipients by :

Download or read book Analytical Profiles of Drug Substances and Excipients written by and published by Academic Press. This book was released on 1992-02-03 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances brings this information together into one source.