Nitric Oxide And Free Radicals In Peripheral Neurotransmission

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Nitric Oxide and Free Radicals in Peripheral Neurotransmission

Author : Stanley Kalsner
Publisher : Springer Science & Business Media
ISBN 13 : 1461213282
Total Pages : 374 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Nitric Oxide and Free Radicals in Peripheral Neurotransmission by : Stanley Kalsner

Download or read book Nitric Oxide and Free Radicals in Peripheral Neurotransmission written by Stanley Kalsner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" is a welcome addition to the literature and describes current research into the role of nitric oxide in the peripheral nervous system and its associated organs. Topics covered range from general consideration of nitrergic transmission, in its broadest sense, to elaboration of our current understanding of the role of nitric oxide in transmission in individual peripheral organs, including its role as a backup, or alternate as well as chief transmitter. The influence of nitric oxide and related compounds on the more conventional modes of autonomic transmission are also considered. Aimed at students and researchers in the areas of neuroscience and physiology, "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" also covers the emerging role of abnormal nitric oxide function in disease states and, where appropriate, as potential avenues of therapy.

Nitric Oxide and Free Radicals in Peripheral Neurotransmission

Author : Stanley Kalsner
Publisher : Springer Science & Business Media
ISBN 13 : 9780817640705
Total Pages : 374 pages
Book Rating : 4.6/5 (47 download)

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Book Synopsis Nitric Oxide and Free Radicals in Peripheral Neurotransmission by : Stanley Kalsner

Download or read book Nitric Oxide and Free Radicals in Peripheral Neurotransmission written by Stanley Kalsner and published by Springer Science & Business Media. This book was released on 2000-06-16 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" is a welcome addition to the literature and describes current research into the role of nitric oxide in the peripheral nervous system and its associated organs. Topics covered range from general consideration of nitrergic transmission, in its broadest sense, to elaboration of our current understanding of the role of nitric oxide in transmission in individual peripheral organs, including its role as a backup, or alternate as well as chief transmitter. The influence of nitric oxide and related compounds on the more conventional modes of autonomic transmission are also considered. Aimed at students and researchers in the areas of neuroscience and physiology, "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" also covers the emerging role of abnormal nitric oxide function in disease states and, where appropriate, as potential avenues of therapy.

Nitric Oxide and Free Radicals in Peripheral Neurotransmission

Author : Stanley Kalsner
Publisher : Birkhäuser
ISBN 13 : 9781461270966
Total Pages : 357 pages
Book Rating : 4.2/5 (79 download)

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Book Synopsis Nitric Oxide and Free Radicals in Peripheral Neurotransmission by : Stanley Kalsner

Download or read book Nitric Oxide and Free Radicals in Peripheral Neurotransmission written by Stanley Kalsner and published by Birkhäuser. This book was released on 2012-10-21 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" is a welcome addition to the literature and describes current research into the role of nitric oxide in the peripheral nervous system and its associated organs. Topics covered range from general consideration of nitrergic transmission, in its broadest sense, to elaboration of our current understanding of the role of nitric oxide in transmission in individual peripheral organs, including its role as a backup, or alternate as well as chief transmitter. The influence of nitric oxide and related compounds on the more conventional modes of autonomic transmission are also considered. Aimed at students and researchers in the areas of neuroscience and physiology, "Nitric Oxide and Free Radicals in Peripheral Neurotransmission" also covers the emerging role of abnormal nitric oxide function in disease states and, where appropriate, as potential avenues of therapy.

Nitric Oxide Synthase

Author : Seyed Soheil Saeedi Saravi
Publisher : BoD – Books on Demand
ISBN 13 : 953513163X
Total Pages : 250 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Nitric Oxide Synthase by : Seyed Soheil Saeedi Saravi

Download or read book Nitric Oxide Synthase written by Seyed Soheil Saeedi Saravi and published by BoD – Books on Demand. This book was released on 2017-05-17 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.

Signal Transduction and the Gasotransmitters

Author : Rui Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1592598064
Total Pages : 372 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Signal Transduction and the Gasotransmitters by : Rui Wang

Download or read book Signal Transduction and the Gasotransmitters written by Rui Wang and published by Springer Science & Business Media. This book was released on 2004-06-11 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.

Glutathione In The Nervous System

Author : Christopher Ari Shaw
Publisher : CRC Press
ISBN 13 : 9781560326434
Total Pages : 410 pages
Book Rating : 4.3/5 (264 download)

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Book Synopsis Glutathione In The Nervous System by : Christopher Ari Shaw

Download or read book Glutathione In The Nervous System written by Christopher Ari Shaw and published by CRC Press. This book was released on 1998-02-27 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this text is to focus readers attention on three major areas; the origin and localization of GSH in the nervous system; the multiple effects of GSH on neural health activity; and the potential for alterations on GSH status to lead to neurological damage of the type observed in amyotrophic lateral sclerosis, Parkinson's disease and other neurological disorders. The text also touches upon the additional roles of the antoxidant GSH, including possible neurotransmitter action, redox modulation of ionotropic receptor function, and neuroprotection against exicitoxic actions of glutamate.

NOx Related Chemistry

Author :
Publisher : Academic Press
ISBN 13 : 0128018372
Total Pages : 388 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis NOx Related Chemistry by :

Download or read book NOx Related Chemistry written by and published by Academic Press. This book was released on 2015-01-08 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: NOx Related Chemistry is a volume of a series that presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bio-inorganic to solid state studies. This acclaimed serial features reviews written by experts in the field and serves as an indispensable reference to advanced researchers. Each volume contains an index, and each chapter is fully referenced. - Best-qualified scientists write on their own recent results dealing with basic fundamentals of NO-chemistry, with an eye into biological and environmental issues - Editors and authors are recognized scientists in the field - Features comprehensive reviews on the latest developments - An indispensable reference to advanced researchers

Magnesium in the Central Nervous System

Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)

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Book Synopsis Magnesium in the Central Nervous System by : Robert Vink

Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Handbook on Immunosenescence

Author : Tamas Fulop
Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Chemistry of Biologically Potent Natural Products and Synthetic Compounds

Author : Shahid Ul-Islam
Publisher : John Wiley & Sons
ISBN 13 : 1119640342
Total Pages : 434 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Chemistry of Biologically Potent Natural Products and Synthetic Compounds by : Shahid Ul-Islam

Download or read book Chemistry of Biologically Potent Natural Products and Synthetic Compounds written by Shahid Ul-Islam and published by John Wiley & Sons. This book was released on 2021-06-29 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms. Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Chemistry of Biologically Potent Natural Products and Synthetic Compounds provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.

Neurodegenerative Diseases

Author : Rommy von Bernhardi
Publisher : Nova Publishers
ISBN 13 : 9781604561678
Total Pages : 240 pages
Book Rating : 4.5/5 (616 download)

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Book Synopsis Neurodegenerative Diseases by : Rommy von Bernhardi

Download or read book Neurodegenerative Diseases written by Rommy von Bernhardi and published by Nova Publishers. This book was released on 2008 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses in detail the different hypothesis and experimental evidence regarding the neurobiological mechanisms involved in neurodegenerative pathology, with an emphasis in Alzheimer's and Parkinson's disease. Since there are many hypotheses for neurodegenerative diseases, there is a real need for a comprehensive view, allowing for integration of the different views for the pathogenic mechanisms of the disease.

The Endothelium

Author : Michel Félétou
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041230
Total Pages : 309 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Endothelium by : Michel Félétou

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Advances in Metallodrugs

Author : Shahid Ul Islam
Publisher : John Wiley & Sons
ISBN 13 : 1119640423
Total Pages : 432 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Advances in Metallodrugs by : Shahid Ul Islam

Download or read book Advances in Metallodrugs written by Shahid Ul Islam and published by John Wiley & Sons. This book was released on 2020-07-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlights the application areas of newly discovered metallodrugs. It can prove beneficial for researchers, investigators and scientists whose work involves inorganic and coordination chemistry, medical science, pharmacy, biotechnology and biomedical engineering.

Caffeine in Food and Dietary Supplements

Author : Leslie A. Pray
Publisher :
ISBN 13 : 9780309297493
Total Pages : 0 pages
Book Rating : 4.2/5 (974 download)

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Book Synopsis Caffeine in Food and Dietary Supplements by : Leslie A. Pray

Download or read book Caffeine in Food and Dietary Supplements written by Leslie A. Pray and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements and to identify data gaps. Scientists with expertise in food safety, nutrition, pharmacology, psychology, toxicology, and related disciplines; medical professionals with pediatric and adult patient experience in cardiology, neurology, and psychiatry; public health professionals; food industry representatives; regulatory experts; and consumer advocates discussed the safety of caffeine in food and dietary supplements, including, but not limited to, caffeinated beverage products, and identified data gaps. Caffeine, a central nervous stimulant, is arguably the most frequently ingested pharmacologically active substance in the world. Occurring naturally in more than 60 plants, including coffee beans, tea leaves, cola nuts and cocoa pods, caffeine has been part of innumerable cultures for centuries. But the caffeine-in-food landscape is changing. There are an array of new caffeine-containing energy products, from waffles to sunflower seeds, jelly beans to syrup, even bottled water, entering the marketplace. Years of scientific research have shown that moderate consumption by healthy adults of products containing naturally-occurring caffeine is not associated with adverse health effects. The changing caffeine landscape raises concerns about safety and whether any of these new products might be targeting populations not normally associated with caffeine consumption, namely children and adolescents, and whether caffeine poses a greater health risk to those populations than it does for healthy adults. This report delineates vulnerable populations who may be at risk from caffeine exposure; describes caffeine exposure and risk of cardiovascular and other health effects on vulnerable populations, including additive effects with other ingredients and effects related to pre-existing conditions; explores safe caffeine exposure levels for general and vulnerable populations; and identifies data gaps on caffeine stimulant effects.

The Encylopedia of Molecular Biology

Author : Sir John Kendrew
Publisher : John Wiley & Sons
ISBN 13 : 1444313843
Total Pages : 1201 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis The Encylopedia of Molecular Biology by : Sir John Kendrew

Download or read book The Encylopedia of Molecular Biology written by Sir John Kendrew and published by John Wiley & Sons. This book was released on 2009-07-06 with total page 1201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encylopaedia of Molecular Biology is a truly unique work of reference. 6000 definitions cover the entire spectrum of molecular life science The complete one-volume guide to understanding the way molecular biology is transforming medicine and agriculture Long and short entries written by over 300 of the world's finest researchers For rapid research or detailed study ... this is the A to Z of the New Biology

Systems Biology of Free Radicals and Antioxidants

Author : Ismail Laher
Publisher : Springer
ISBN 13 : 9783642300172
Total Pages : 0 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Systems Biology of Free Radicals and Antioxidants by : Ismail Laher

Download or read book Systems Biology of Free Radicals and Antioxidants written by Ismail Laher and published by Springer. This book was released on 2014-06-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings.

The Promise of Low Dose Naltrexone Therapy

Author : Elaine A. Moore
Publisher : McFarland
ISBN 13 : 0786452587
Total Pages : 224 pages
Book Rating : 4.7/5 (864 download)

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Book Synopsis The Promise of Low Dose Naltrexone Therapy by : Elaine A. Moore

Download or read book The Promise of Low Dose Naltrexone Therapy written by Elaine A. Moore and published by McFarland. This book was released on 2009-01-22 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naltrexone is an opiate antagonist drug developed in the 1970s and approved by the FDA in 1984 for opiate and drug abuse treatment. When used at much lower doses in an off-label protocol referred to as low dose naltrexone (LDN), the drug has been shown to halt disease progression in Crohn's disease and certain cancers, to reduce symptoms in multiple sclerosis and autism, and to improve numerous autoimmune and neurodegenerative conditions, including Parkinson's disease and amyotrophic lateral sclerosis (ALS). Grounded in clinical and scientific research, this book describes the history of naltrexone, its potential therapeutic uses, its effects on the immune system, its pharmacological properties, and how the drug is administered. It also lists fillers and compounding pharmacies, doctors who prescribe LDN, and patient resources, and includes interviews with LDN patients and researchers.