New Trends In Radiopharmaceutical Synthesis Quality Assurance And Regulatory Control

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New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

Author : Ali M. Emran
Publisher : Springer Science & Business Media
ISBN 13 : 1489906266
Total Pages : 504 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control by : Ali M. Emran

Download or read book New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control written by Ali M. Emran and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marking the 200th National Meeting of the American Chemical Society, The Division of Nuclear Chemistry and Technology hosted a group of about 90 scientists from 15 different countries to discuss the new trends in radiopharmaceutical synthesis, quality assurance and regulatory control. This event took place in Washington, D.C. on August 27-30, 1990. When I first suggested the idea for this symposium, a group of scientists who pioneered the proposed topics offered their help to organize and run such a big task with me. Their names are listed here in appreciation. Thomas E. Boothe Cyclotron Facility, Mt. Sinai Medical Center, Miami Beach, Florida, USA Robert F. Dannals Division of Nuclear Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA Anthony L. Feliu Julich Nuclear Research Center, Julich, Germany Joanna S. Fowler Chemistry Department, Brookhaven National Laboratory, Upton, New York, USA George W. Kabalka Department of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hank F. Kung Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA James F. Lamb Imagents, Inc., Houston, Texas, USA Harold A. O'Brien, Jr. Los Alamos National Laboratory, Los Alamos, New Mexico, USA Joseph R. Peterson Dept. of Chemistry, University of Tennessee, Knoxville, Tennessee, USA Hernan Vera Ruiz International Atomic Energy Agency, Vienna, Austria Roy S. Tilbury University of Texas, M. D. Anderson Cancer Center, Houston, Texas, USA In addition, a number of distinguished colleagues have participated in the process of reviewing the manuscripts presented in this volume. Their effort is sincerely acknowledged.

New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control

Author : Ali M. Emran
Publisher :
ISBN 13 : 9781489906274
Total Pages : 536 pages
Book Rating : 4.9/5 (62 download)

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Book Synopsis New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control by : Ali M. Emran

Download or read book New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control written by Ali M. Emran and published by . This book was released on 2014-01-15 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Radiopharmaceuticals

Author : Michael R. Kilbourn
Publisher : John Wiley & Sons
ISBN 13 : 1119500540
Total Pages : 768 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Handbook of Radiopharmaceuticals by : Michael R. Kilbourn

Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine

Author : Richard J. Kowalsky
Publisher :
ISBN 13 : 9781582123639
Total Pages : pages
Book Rating : 4.1/5 (236 download)

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Book Synopsis Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine by : Richard J. Kowalsky

Download or read book Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine written by Richard J. Kowalsky and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Completed revised and updated, Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine, 4th Edition is the radiopharmaceutical bible for nuclear pharmacists, nuclear medicine physicians, and nuclear medicine technologists. Useful in educational programs across these disciplines, it also serves as a key reference in preparation for specialty board examination in nuclear medicine and nuclear pharmacy. The book contains essential information required by state and federal radiation licensing organization for specialty practitioners preparing to become authorized nuclear pharmacists or authorized nuclear medicine physicians. Key Features: All chapters are entirely reorganized and revised to reflect the latest developments in the field. Chapters new to the fourth edition cover of range of topics including Adverse Reactions to Radiopharmaceuticals, Pregnancy and Pediatrics, Localization Mechanisms of Radiopharmaceuticals, Non-Radioactive Pharmaceuticals, PET Manufacturing, and Radiopharmaceutical Distribution. Over 500 figures and 200 tables-many in full-color-underscore key concepts. Table of Contents: Diagnostic Imaging, Nuclear Medicine, and Nuclear Pharmacy; Historical Perspectives in Nuclear Pharmacy: Practice, Education and Specialty Certification; Principles of Radioactivity; Radionuclide Production; Interactions of Radiation with Matter; Radiation Detection and Instrumentation; Radiation Safety; Radiation Biology; Radiopharmaceutical Chemistry: General Topics; Radiopharmaceutical Chemistry: Technetium Agents; Radiopharmaceutical Chemistry: Non-Technetium Agents; Radiopharmaceutical Chemistry: PET Agents; The Nuclear Pharmacy; Quality Control in Nuclear Pharmacy; (New Chapter Number) Formulation Problems of Radiopharmaceuticals Considerations for the Safe Handling of Radiolabeled Blood Products PET Manufacturing and Radiopharmaceutical Distribution Licensing and Regulatory Control - Nuclear; Radiopharmaceuticals and the FDA; Radiopharmaceuticals as Compounded Sterile Products; Mechanisms of Localization of Radiopharmaceuticals; Pregnancy, Pediatric and Breastfeeding Considerations; Adverse reactions to radiopharmaceuticals; Non-Radioactive pharmaceuticals used in nuclear medicine; Brain; Thyroid; Heart; Lung; Liver, Spleen, and Gastrointestinal System; Kidney; Bone; Miscellaneous; Whole Body Imaging Procedures; PET Whole Body Imaging Procedures (new title - formerly Clinical PET Procedures); Therapeutic Applications of Radioactive Agents; Index; Appendices"--

National Library of Medicine Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1184 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1992 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1628 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Chemists’ Views of Imaging Centers

Author : Ali M. Emran
Publisher : Springer Science & Business Media
ISBN 13 : 1475796706
Total Pages : 528 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Chemists’ Views of Imaging Centers by : Ali M. Emran

Download or read book Chemists’ Views of Imaging Centers written by Ali M. Emran and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: To continue the support for the growing trend of chemistry involvement in nuclear medicine, the Division of Nuclear Chemistry and Technology (DNCT) of the American Chemical Society (ACS) planned for a symposium to cover this aspect. This was expressed in arequest to me, as a member of the Program Committee, to organize a symposium on topics related to nuclear and radiochemistry applications to nuclear medicine. Realizing the growing interest in imaging, specially with positron emitting radioisotopes, I invited several colleagues to study with me the idea of imaging centers and the involvement of chemists in their structure and function. The formulated Organizing Committee supported this idea which evolved in proposing an extended international symposium to be held in conjunction with the 206th ACS National meeting in Chicago, Illinois, U. S. A. on August 22-27, 1993. The following are the members of the Organizing Committee: Jorge R. Barrio, Ph. D. Thomas E. Boothe, Ph. D. J. Robert Dahl, Ph. D. Robert F. Dannals, Ph. D. Bruce R. Erdal, Ph. D. Mark M. Goodman, Ph. D. George W. Kabalka, Ph. D. James F. Lamb, Ph. D. Ronald G. Manning, Ph. D. Henry C. Padgett, Ph. D. Roy S. Tilbury, Ph. D. Steven W. Yates, Ph. D. and Ali M. Emran, Ph. D.

Radiopharmaceuticals

Author : Farid A. Badria
Publisher : BoD – Books on Demand
ISBN 13 : 1839696591
Total Pages : 228 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Radiopharmaceuticals by : Farid A. Badria

Download or read book Radiopharmaceuticals written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2022-06-15 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy discusses the importance of radiopharmaceuticals and their environmental, pharmaceutical, diagnostic, therapeutic, and research applications. Chapters address such topics as the fundamentals of radiopharmaceutical chemistry and preparation, fabrication, materials manipulation, and characterization of radiopharmaceuticals, applications of radiopharmaceuticals in preclinical studies, radiopharmaceuticals in modern cancer therapy, and new trends in preparation, biodistribution, and pharmacokinetics of radiopharmaceuticals in diagnosis and research.

Trends in Radiopharmaceuticals (ISTR-2019)

Author : International Atomic Energy Agency
Publisher :
ISBN 13 : 9789201177209
Total Pages : 0 pages
Book Rating : 4.1/5 (772 download)

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Book Synopsis Trends in Radiopharmaceuticals (ISTR-2019) by : International Atomic Energy Agency

Download or read book Trends in Radiopharmaceuticals (ISTR-2019) written by International Atomic Energy Agency and published by . This book was released on 2021-02-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of radiopharmaceuticals is an important tool not only for management of diseases and dysfunctions, but also for better understanding human diseases and developing effective treatment options, such as in the case of neurology. In this context, there is concern of continuous, impressive progress in nuclear medicine which is linked to the development of new radiopharmaceuticals and efficient production of relevant radioisotopes. These proceedings highlight the main findings and developments discussed during the International Symposium on Trends in Radiopharmaceuticals. They cover the key issues and advances in the field of radiopharmaceuticals from development, production, and use of diagnostic, therapeutic, and theranostic radioisotopes and radiopharmaceuticals, as well as regulatory and licensing issues related to their production. Additional topics addressed were education, certification and training methodologies. A supplementary file contains the detailed programme of the symposium and the abstracts of all oral and poster presentations.

Handbook of Radiopharmaceuticals

Author : Michael J. Welch
Publisher : John Wiley & Sons
ISBN 13 : 9780471495604
Total Pages : 872 pages
Book Rating : 4.4/5 (956 download)

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Book Synopsis Handbook of Radiopharmaceuticals by : Michael J. Welch

Download or read book Handbook of Radiopharmaceuticals written by Michael J. Welch and published by John Wiley & Sons. This book was released on 2003-01-17 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States

Nuclear Medicine Textbook

Author : Duccio Volterrani
Publisher : Springer
ISBN 13 : 3319955640
Total Pages : 1331 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Nuclear Medicine Textbook by : Duccio Volterrani

Download or read book Nuclear Medicine Textbook written by Duccio Volterrani and published by Springer. This book was released on 2019-08-10 with total page 1331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building on the traditional concept of nuclear medicine, this textbook presents cutting-edge concepts of hybrid imaging and discusses the close interactions between nuclear medicine and other clinical specialties, in order to achieve the best possible outcomes for patients. Today the diagnostic applications of nuclear medicine are no longer stand-alone procedures, separate from other diagnostic imaging modalities. This is especially true for hybrid imaging guided interventional radiology or surgical procedures. Accordingly, today’s nuclear medicine specialists are actually specialists in multimodality imaging (in addition to their expertise in the diagnostic and therapeutic uses of radionuclides). This new role requires a new core curriculum for training nuclear medicine specialists. This textbook is designed to meet these new educational needs, and to prepare nuclear physicians and technologists for careers in this exciting specialty.

Quality Control in the Production of Radiopharmaceuticals

Author : International Atomic Energy Agency
Publisher :
ISBN 13 : 9789201079183
Total Pages : 148 pages
Book Rating : 4.0/5 (791 download)

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Book Synopsis Quality Control in the Production of Radiopharmaceuticals by : International Atomic Energy Agency

Download or read book Quality Control in the Production of Radiopharmaceuticals written by International Atomic Energy Agency and published by . This book was released on 2018-11-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances have led to the production of new radiopharmaceuticals and availability of new production routes. Various new diagnostic agents in the field (such as Ga-68 radiopharmaceuticals and generators) as well as therapeutic agents (such as alpha emitters) have been added to the clinician's menu. It is essential that radiopharmaceuticals are prepared within a robust quality control system encompassing materials and personnel, with adequate documentation, and continuous review of ongoing results. This publication provides guidelines and best practices for the quality control of medical radioisotopes and radiopharmaceuticals. It was written by a group of experts with experience across a range of radiopharmaceuticals and is intended to support professionals in the preparation of good quality and safe products to be used in nuclear medicine procedures.

Basic Sciences of Nuclear Medicine

Author : Magdy M. Khalil
Publisher : Springer Nature
ISBN 13 : 3030652459
Total Pages : 571 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Basic Sciences of Nuclear Medicine by : Magdy M. Khalil

Download or read book Basic Sciences of Nuclear Medicine written by Magdy M. Khalil and published by Springer Nature. This book was released on 2021-05-26 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.

Nuclear Imaging in Drug Discovery, Development, and Approval

Author : BURNS
Publisher : Springer Science & Business Media
ISBN 13 : 1468468081
Total Pages : 347 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Nuclear Imaging in Drug Discovery, Development, and Approval by : BURNS

Download or read book Nuclear Imaging in Drug Discovery, Development, and Approval written by BURNS and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is the purpose and business of the pharmaceutical industry to dis cover, develop, and make available drugs for the care of the sick. The purpose of universities and national laboratories is to provide people and scientific knowledge that can help in the process. This book presents the combined efforts of scientists from the drug in dustry, academic laboratories and national laboratories to describe advances in radiotracer technology in studies on experimental ani mals and living human beings. The authors believe that the technol ogy is now ready for widespread application in the pharmaceutical industry. The goal of this book is to help bring this about. The field of Nuclear Medicine is based on the concept that, if treatment of disease is chemical, the patient's diagnosis should be chemical. Anatomy and histopathology have been the principle ba sis for making a diagnosis. Histopathologic data suffer from being descriptive, subjective, not quantifiable, and based on the study of dead tissue. The era of histopathology as the dominant concept in medical practice is coming to an end. Histopathologic findings are often heterogeneous and a single biopsy will at times not reveal the true nature of the disease, such as the grading of malignancy. Far greater accuracy of staging of disease and in the planning of treat ment is possible through chemistry, as well as by making possible a more suitable selection of a histological biopsy site.

Comprehensive Handbook of Iodine

Author : Victor R Preedy
Publisher : Academic Press
ISBN 13 : 0080920861
Total Pages : 1335 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Comprehensive Handbook of Iodine by : Victor R Preedy

Download or read book Comprehensive Handbook of Iodine written by Victor R Preedy and published by Academic Press. This book was released on 2009-03-17 with total page 1335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid. The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies. Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders. This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied. Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today Includes information on iodine-related diseases, including those that are common, preventable and treatable Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact

Handbook of Nuclear Chemistry

Author : Attila Vértes
Publisher : Springer Science & Business Media
ISBN 13 : 9781402013058
Total Pages : 422 pages
Book Rating : 4.0/5 (13 download)

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Book Synopsis Handbook of Nuclear Chemistry by : Attila Vértes

Download or read book Handbook of Nuclear Chemistry written by Attila Vértes and published by Springer Science & Business Media. This book was released on 2003 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impressive in its overall size and scope, this five-volume reference work provides researchers with the tools to push them into the forefront of the latest research. The Handbook covers all of the chemical aspects of nuclear science starting from the physical basics and including such diverse areas as the chemistry of transactinides and exotic atoms as well as radioactive waste management and radiopharmaceutical chemistry relevant to nuclear medicine. The nuclear methods of the investigation of chemical structure also receive ample space and attention. The international team of authors consists of 77 world-renowned experts - nuclear chemists, radiopharmaceutical chemists and physicists - from Austria, Belgium, Germany, Great Britain, Hungary, Holland, Japan, Russia, Sweden, Switzerland and the United States. The Handbook is an invaluable reference for nuclear scientists, biologists, chemists, physicists, physicians practicing nuclear medicine, graduate students and teachers - virtually all who are involved in the chemical and radiopharmaceutical aspects of nuclear science. The Handbook also provides for further reading through its rich selection of references.

Basic Sciences of Nuclear Medicine

Author : Magdy Khalil
Publisher : Springer Science & Business Media
ISBN 13 : 3540859624
Total Pages : 420 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Basic Sciences of Nuclear Medicine by : Magdy Khalil

Download or read book Basic Sciences of Nuclear Medicine written by Magdy Khalil and published by Springer Science & Business Media. This book was released on 2010-10-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.