New Horizons In Tumor Microenvironment Biology And Therapy Implications For New Therapies Vol Ii

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Cancer Stem Cells: New Horizons in Cancer Therapies

Author : Surajit Pathak
Publisher : Springer Nature
ISBN 13 : 9811551200
Total Pages : 369 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Cancer Stem Cells: New Horizons in Cancer Therapies by : Surajit Pathak

Download or read book Cancer Stem Cells: New Horizons in Cancer Therapies written by Surajit Pathak and published by Springer Nature. This book was released on 2020-10-17 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.

New Horizons in Tumor Microenvironment Biology and Therapy: Implications for New Therapies Vol. II

Author : Andreas Pircher
Publisher : Frontiers Media SA
ISBN 13 : 2889768295
Total Pages : 254 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis New Horizons in Tumor Microenvironment Biology and Therapy: Implications for New Therapies Vol. II by : Andreas Pircher

Download or read book New Horizons in Tumor Microenvironment Biology and Therapy: Implications for New Therapies Vol. II written by Andreas Pircher and published by Frontiers Media SA. This book was released on 2022-08-19 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tumor Microenvironment

Author : Alexander Birbrair
Publisher : Springer
ISBN 13 : 9783030445201
Total Pages : 208 pages
Book Rating : 4.4/5 (452 download)

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Book Synopsis Tumor Microenvironment by : Alexander Birbrair

Download or read book Tumor Microenvironment written by Alexander Birbrair and published by Springer. This book was released on 2021-06-27 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Systems Biology of Tumor Microenvironment

Author : Katarzyna A. Rejniak
Publisher : Springer
ISBN 13 : 3319420232
Total Pages : 249 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Systems Biology of Tumor Microenvironment by : Katarzyna A. Rejniak

Download or read book Systems Biology of Tumor Microenvironment written by Katarzyna A. Rejniak and published by Springer. This book was released on 2016-10-13 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the complexity of tumor microenvironments during cancer development, progression and treatment. Each chapter presents a different mathematical model designed to investigate the interactions between tumor cells and the surrounding stroma and stromal cells. The topics covered in this book include the quantitative image analysis of a tumor microenvironment, the microenvironmental barriers in oxygen and drug delivery to tumors, the development of tumor microenvironmental niches and sanctuaries, intravenous transport of the circulating tumor cells, the role of the tumor microenvironment in chemotherapeutic interventions, the interactions between tumor cells, the extracellular matrix, the interstitial fluid, and the immune and stromal cells. Mathematical models discussed here embrace both continuous and agent-based approaches, as well as mathematical frameworks of solid mechanics, fluid dynamics and optimal control theory. The topics in each chapter will be of interest to a biological community wishing to apply the mathematical methods to interpret their experimental data, and to a biomathematical audience interested in exploring how mathematical models can be used to address complex questions in cancer biology.

Oxford Textbook of Oncology

Author : David J. Kerr
Publisher : Oxford University Press
ISBN 13 : 0191065110
Total Pages : 832 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Oxford Textbook of Oncology by : David J. Kerr

Download or read book Oxford Textbook of Oncology written by David J. Kerr and published by Oxford University Press. This book was released on 2016-01-28 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the Oxford Textbook of Oncology reflects current best practice in the multidisciplinary management of cancer, written and edited by internationally recognised leaders in the field. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

Immune Checkpoint Inhibitors in Cancer

Author : Fumito Ito
Publisher : Elsevier Health Sciences
ISBN 13 : 0323549500
Total Pages : 400 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Immune Checkpoint Inhibitors in Cancer by : Fumito Ito

Download or read book Immune Checkpoint Inhibitors in Cancer written by Fumito Ito and published by Elsevier Health Sciences. This book was released on 2018-09-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of the latest clinical information and guidelines for cancer checkpoint inhibitors and their implications for specific types of cancers. This practical title by Drs. Fumito Ito and Marc Ernstoff synthesizes the most up-to-date research and clinical guidance available on immune checkpoint inhibitors and presents this information in a compact, easy-to-digest resource. It’s an ideal concise reference for trainee and practicing medical oncologists, as well as those in research. Discusses the current understanding of how to best harness the immune system against different types of cancer at various stages. Helps you translate current research and literature into practical information for daily practice. Presents information logically organized by disease site. Covers tumor immunology and biology; toxicities associated with immune checkpoint inhibitors; and future outlooks. Consolidates today’s available information on this timely topic into one convenient resource.

Nanoparticles in Cancer Therapy: Novel Concepts, Mechanisms and Applications

Author : Qingxin Mu
Publisher : Frontiers Media SA
ISBN 13 : 2889458105
Total Pages : 162 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Nanoparticles in Cancer Therapy: Novel Concepts, Mechanisms and Applications by : Qingxin Mu

Download or read book Nanoparticles in Cancer Therapy: Novel Concepts, Mechanisms and Applications written by Qingxin Mu and published by Frontiers Media SA. This book was released on 2019-04-03 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the invention of nanomedicine decades ago, considerable progresses have been made, especially with cancer as a target. Nanoparticles have been proven to be powerful imaging tools or potent agents for cancer diagnosis, treatment and prevention. Active research spread from fundamental research to clinical investigations. This topic intends to cover several important aspects in this field including nanocarrier development, gene delivery, intrinsically active nanoparticles, tumor microenvironment, immunology, and toxicity.

The M2 Macrophage

Author : Tamás Röszer
Publisher : Springer Nature
ISBN 13 : 3030504808
Total Pages : 224 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis The M2 Macrophage by : Tamás Röszer

Download or read book The M2 Macrophage written by Tamás Röszer and published by Springer Nature. This book was released on 2020-08-03 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.

Cancer Metastasis

Author : Yasemin Basbinar
Publisher : BoD – Books on Demand
ISBN 13 : 1789846323
Total Pages : 154 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Cancer Metastasis by : Yasemin Basbinar

Download or read book Cancer Metastasis written by Yasemin Basbinar and published by BoD – Books on Demand. This book was released on 2018-12-05 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastasis of cancer cells from primary tumor site to secondary locations is considered a late event in multistep tumorigenesis, and causes most cancer-related mortality. The process from the spreading of cancer cells to the seeding of newly formed tumor colonizations is governed by sequential events, including local invasion, intravasation into stroma and blood vessels, survival in circulation, extravasation, and colonization at secondary tumor sites. Cancer research provides information on the fate of metastatic cancer cells in each sequential movement or heterogeneous tumor microenvironment. However, the complexity of this mechanism remains the most stringent concept of cancer management. This book provides information for cancer researchers on metastatic phenotypes of cancer cells, and diverse promoting factors and molecular mechanisms of metastasis.

Angiogenesis Inhibition

Author : Rüdiger Liersch
Publisher : Springer Science & Business Media
ISBN 13 : 3540782818
Total Pages : 238 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Angiogenesis Inhibition by : Rüdiger Liersch

Download or read book Angiogenesis Inhibition written by Rüdiger Liersch and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis is attracting increased scientific and clinical interest. The identification of novel mediators and targeting molecules has led to significant progress in our understanding of tumor angiogenesis and tumor vessel targeting. Important advances in cancer treatment have already emerged, and in the future, blood vessel targeting will play a significant role within individualized therapeutic strategies. This volume provides a general overview of the latest developments in angiogenesis inhibition in cancer. All aspects from the bench to the bedside are considered, with detailed attention both to basic research and to its translation into clinical practice. Individual chapters are devoted to the roles of angiopoietins, HIF-1a, chemokines, PDGF and VEGF, and vascular integrins. The latest results of clinical trials are presented, and various advanced targeting strategies are discussed. This book will be invaluable to all who wish to learn of the most recent advances in this exciting field.

Interleukins in Cancer Biology

Author : Arseniy Yuzhalin
Publisher : Academic Press
ISBN 13 : 0128013338
Total Pages : 361 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Interleukins in Cancer Biology by : Arseniy Yuzhalin

Download or read book Interleukins in Cancer Biology written by Arseniy Yuzhalin and published by Academic Press. This book was released on 2014-06-27 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interleukins in Cancer Biology responds to the growing need for credible and up-to-date information about the impact of interleukins on occurrence, development and progression of cancer. It provides reliable information about all known interleukins (38), describes recent discoveries in the field, and moreover, suggests further directions of research on the most promising aspects of this topic. The structure and presentation of the work is very understandable and clear with attention to detail maintained throughout. There are multiple illustrations throughout to help in comprehending and remembering the most important facts. . Summarizes and discusses existing facts on the impact of all known interleukins in occurrence, development, and progression of cancer Categorizes and clarifies all interleukins based on their role in cancer Contains comprehensive and exhaustive information on each molecule

Advanced Healthcare Materials

Author : Ashutosh Tiwari
Publisher : John Wiley & Sons
ISBN 13 : 1118773683
Total Pages : 421 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Advanced Healthcare Materials by : Ashutosh Tiwari

Download or read book Advanced Healthcare Materials written by Ashutosh Tiwari and published by John Wiley & Sons. This book was released on 2014-05-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive and interdisciplinary view of cutting-edge research on advanced materials for healthcare technology and applications Advanced healthcare materials are attracting strong interest in fundamental as well as applied medical science and technology. This book summarizes the current state of knowledge in the field of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, and up-and-coming bioengineering devices. Advanced Healthcare Materials highlights the key features that enable the design of stimuli-responsive smart nanoparticles, novel biomaterials, and nano/micro devices for either diagnosis or therapy, or both, called theranostics. It also presents the latest advancements in healthcare materials and medical technology. The senior researchers from global knowledge centers have written topics including: State-of-the-art of biomaterials for human health Micro- and nanoparticles and their application in biosensors The role of immunoassays Stimuli-responsive smart nanoparticles Diagnosis and treatment of cancer Advanced materials for biomedical application and drug delivery Nanoparticles for diagnosis and/or treatment of Alzheimers disease Hierarchical modelling of elastic behavior of human dental tissue Biodegradable porous hydrogels Hydrogels in tissue engineering, drug delivery, and wound care Modified natural zeolites Supramolecular hydrogels based on cyclodextrin poly(pseudo)rotaxane Polyhydroxyalkanoate-based biomaterials Biomimetic molecularly imprinted polymers

Comprehensive Biomaterials II

Author : Kevin Healy
Publisher : Elsevier
ISBN 13 : 0081006926
Total Pages : 4865 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Biomaterials II by : Kevin Healy

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Targeted Cancer Therapy

Author : Gail Wilkes
Publisher : Jones & Bartlett Learning
ISBN 13 : 0763772119
Total Pages : 361 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Targeted Cancer Therapy by : Gail Wilkes

Download or read book Targeted Cancer Therapy written by Gail Wilkes and published by Jones & Bartlett Learning. This book was released on 2010-08-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Cancer Therapy: A Handbook for Nurses is an essential guide for nurses interested in the latest discoveries in oncology. Covering the most recent treatment option of transforming cancer into a chronic illness, Targeted Cancer Therapy provides nurses with the information they need to understand this and future developments in the field. This comprehensive but easy-to-understand text takes nurses through foundational concepts in cell and normal biology that are crucial to understanding cancer and targeted therapy. Featuring relevant analogies and easy-to-follow discussions on malignant transformation, metastases, cellular pathways, and toxicities, this one-of-a-kind text enables nurses to quickly get up to speed on key topics and develop care plans for oncology patients. Accessible, comprehensive, informative, Targeted Cancer Therapy is a must-read for every oncology nurse.

Angiogenesis

Author : William D. Figg
Publisher : Springer Science & Business Media
ISBN 13 : 0387715185
Total Pages : 592 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Angiogenesis by : William D. Figg

Download or read book Angiogenesis written by William D. Figg and published by Springer Science & Business Media. This book was released on 2008-05-24 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Judah Folkman is considered the "father of angiogenesis." Because of Folkman's discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. Angiogenesis: An Integrative Approach from Science to Medicine is a comprehensive, concise summary of tumor angiogenesis. It is an up-to-date and authoritative reference for the angiogenesis field as it relates to oncology. This book represents the first collection in a volume of which Folkman is co-editor. Folkman has authored nearly 400 original papers and more than 100 book chapters.

The Interconnection Between the Tumor Microenvironment and Immunotherapy in Brain Tumors

Author : Quan Cheng
Publisher : Frontiers Media SA
ISBN 13 : 2832525652
Total Pages : 418 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Interconnection Between the Tumor Microenvironment and Immunotherapy in Brain Tumors by : Quan Cheng

Download or read book The Interconnection Between the Tumor Microenvironment and Immunotherapy in Brain Tumors written by Quan Cheng and published by Frontiers Media SA. This book was released on 2023-06-08 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanotechnology for Advances in Medical Microbiology

Author : Naga Raju Maddela
Publisher : Springer Nature
ISBN 13 : 9811599165
Total Pages : 414 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Nanotechnology for Advances in Medical Microbiology by : Naga Raju Maddela

Download or read book Nanotechnology for Advances in Medical Microbiology written by Naga Raju Maddela and published by Springer Nature. This book was released on 2021-03-22 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combined fields of Microbiology and Nanotechnology have been most successful in providing novel solutions for protecting the health of humans and environment. This book covers the implications of nano-strategies to combat bacterial pathogens, applications of nanotechniques in microbiology, and innovative advances in the area of medical microbiology. Contents are divided into three sections -- Nanoscience in controlling bacterial pathogens, Nanoscience in Microbiology, Medical Microbiology. This volume is going to provide timely information about the technological advances of Nanoscience in the domain of Microbiology, with a special emphasis on Pathobiology. The book is a useful read for students and researchers in microbiology, nanotechnology and medical microbiology.