New Developments in Nitrogen-Containing Multicomponent Reaction Techniques

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Author :
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1036406229
Total Pages : 269 pages
Book Rating : 4.0/5 (364 download)

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Book Synopsis New Developments in Nitrogen-Containing Multicomponent Reaction Techniques by : Neslihan Demirbas

Download or read book New Developments in Nitrogen-Containing Multicomponent Reaction Techniques written by Neslihan Demirbas and published by Cambridge Scholars Publishing. This book was released on 2024-06-28 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green methods such as microwave irradiation and ultrasound sonication, some of which mostly contain solvent-free reaction conditions or water as solvent and ionic liquids, for synthesizing different compounds. Bringing together the knowledge of an expert team, this book provides a comprehensive overview of the use of green chemistry techniques, which have been frequently used in recent years, providing fewer chemicals, less energy, higher yield, etc. This book supplies a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry, and pharmaceutical science.

Isocyanide-based Multicomponent Reactions

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889634841
Total Pages : 100 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Isocyanide-based Multicomponent Reactions by : Jonathan G. Rudick

Download or read book Isocyanide-based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Advances in Heterocyclic Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 0443237743
Total Pages : 430 pages
Book Rating : 4.4/5 (432 download)

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Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Elsevier. This book was released on 2024-02-07 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry, Volume 142, the latest release in this definitive series, combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. Chapters in this new release include Recent advances in the Synthesis of Benzo[b]furans, Recent Advances in the Synthesis of 6-Membered Heterocycles via Domino and Multicomponent Reactions (from 2017-2022), Multi-component synthesis of isatin based bioactive heterocycles, Recent advances in the chemistry of pyrazolo[1,5-a]pyrimidines, The Literature of Heterocyclic Chemistry, Part XXI, 2021, and much more.Additional sections present the latest Advances in applications of dihydropyridines in organic chemistry and Strategies for the annulation of five-membered sulfur-nitrogen rings to benzene and heterocycles. - Considered the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists - Provides the latest comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Advancing Methods to Synthesize Nitrogen-containing Small Molecules for Catalysis and as Potential Therapeutics

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Author :
Publisher :
ISBN 13 : 9780438430464
Total Pages : 403 pages
Book Rating : 4.4/5 (34 download)

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Book Synopsis Advancing Methods to Synthesize Nitrogen-containing Small Molecules for Catalysis and as Potential Therapeutics by : Zachary Lawrence Palchak

Download or read book Advancing Methods to Synthesize Nitrogen-containing Small Molecules for Catalysis and as Potential Therapeutics written by Zachary Lawrence Palchak and published by . This book was released on 2018 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of the current top grossing pharmaceuticals finds that a vast number of them contain amines. As a result, the development of methodologies for the formation of amine-containing compounds is of high value and great importance. With the ability to treat: cancer, HIV, malaria, diabetes, and depression, as well as other ailments, increased efforts have been made to optimize the production of these compounds to increase yield while decreasing the environmental impact. This work is ongoing, and is a culmination of the fields of organic synthesis, catalysis, green chemistry, and biochemistry. The work in the Larsen group revolves largely around the use of copper-based catalysis to access hindered amine scaffolds through single-step, multicomponent reactions. Further functionalization of these compounds allows for the synthesis of previously unknown, biologically active, [alpha]-amino triazoles. Preparation and analysis of electronically diverse pyridyl triazoles allows for the development of new complexes with platinum and palladium. These pyridyl triazole palladium complexes are highly reactive under mild aerobic conditions when used in Suzuki-Miyaura cross-coupling reactions. Pyridyl pyrazoles are another class of compounds that show promise in the field of catalysis. Utilization of electronically diverse ligands allows for fine-tuning of the resulting complex for both classes of ligands. With further investigation, this may allow for the discovery of new reactivity in organic transformations.

Recent Advances in Synthesizing and Utilizing Nitrogen-containing Heterocycles

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832549187
Total Pages : 101 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Recent Advances in Synthesizing and Utilizing Nitrogen-containing Heterocycles by : Hyun-Joon Ha

Download or read book Recent Advances in Synthesizing and Utilizing Nitrogen-containing Heterocycles written by Hyun-Joon Ha and published by Frontiers Media SA. This book was released on 2024-05-31 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.

Recent Developments in the Synthesis and Applications of Pyridines

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Author :
Publisher : Elsevier
ISBN 13 : 0323914594
Total Pages : 650 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Recent Developments in the Synthesis and Applications of Pyridines by : Parvesh Singh

Download or read book Recent Developments in the Synthesis and Applications of Pyridines written by Parvesh Singh and published by Elsevier. This book was released on 2022-09-17 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry. The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. - Includes a detailed review of recent research on the reactivity, synthesis and applications of pyridines - Features concise accounts of the reactivity, synthetic and optimized protocols - Discusses the medicinal, inorganic and polymer chemistry applications of pyridines

Small Molecule Drug Discovery

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Publisher : Elsevier
ISBN 13 : 0128183500
Total Pages : 358 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Small Molecule Drug Discovery by : Andrea Trabocchi

Download or read book Small Molecule Drug Discovery written by Andrea Trabocchi and published by Elsevier. This book was released on 2019-11-23 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired compounds. The last section comprises an exciting collection of selected case studies on drug discovery enabled by small molecules in the fields of cancer research, CNS diseases and infectious diseases. The discovery of novel molecular entities capable of specific interactions represents a significant challenge in early drug discovery. Small molecules are low molecular weight organic compounds that include natural products and metabolites, as well as drugs and other xenobiotics. When the biological target is well defined and understood, the rational design of small molecule ligands is possible. Alternatively, small molecule libraries are being used for unbiased assays for complex diseases where a target is unknown or multiple factors contribute to a disease pathology. - Outlines modern concepts and synthetic strategies underlying the building of small molecules and their chemical libraries useful for drug discovery - Provides modern biophysical methods to screening small molecule libraries, including high-throughput screening, small molecule microarrays, phenotypic screening and chemical genetics - Presents the most advanced chemoinformatics tools to characterize the structural features of small molecule libraries in terms of chemical diversity and complexity, also including the application of virtual screening approaches - Gives an overview of structural features and classification of natural product-derived small molecules, including carbohydrate derivatives, peptides and peptidomimetics, and alkaloid-inspired small molecules

Diversity Oriented Synthesis

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Publisher : Frontiers Media SA
ISBN 13 : 2889457885
Total Pages : 150 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Diversity Oriented Synthesis by : Andrea Basso

Download or read book Diversity Oriented Synthesis written by Andrea Basso and published by Frontiers Media SA. This book was released on 2019-03-22 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Has the concept of Diversity Oriented Synthesis remained unchanged over these two decades, or do we observe improvements or deviations from the original guidelines drawn by the pioneers? The aim of this Research Topic is to collect contributions on the state-of-the-art and progress of Diversity Oriented Synthesis, and to foresee its shape in the next decade.

Advances in Organic Synthesis: Volume 14

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Publisher : Bentham Science Publishers
ISBN 13 : 9811803722
Total Pages : 309 pages
Book Rating : 4.8/5 (118 download)

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Book Synopsis Advances in Organic Synthesis: Volume 14 by : Atta-ur-Rahman

Download or read book Advances in Organic Synthesis: Volume 14 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-03-30 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following chapters: - “On Water” And “In Water” Strategies for Heterocyclic Transformations - Ionic Liquid Based Polyoxometalates as Functionalized Organic-Inorganic Hybrid Materials for Catalytic Organic Reactions - Recent Advances in the Synthesis and Bio-Applications of some Oxygen and Sulphur Containing Seven Membered Heterocyclic Compounds - Application of Nitriles on the Synthesis of 5-Membered Azaheterocycles: An Update from 2014 To 2020 - The Role of Carbon-Based Solid Acid Catalysts in Organic Synthesis.

Energy and Water Development Appropriations for 1982

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Publisher :
ISBN 13 :
Total Pages : 1742 pages
Book Rating : 4.0/5 (18 download)

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Book Synopsis Energy and Water Development Appropriations for 1982 by : United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development

Download or read book Energy and Water Development Appropriations for 1982 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development and published by . This book was released on 1981 with total page 1742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Energy and Water Development Appropriations for 1983

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Publisher :
ISBN 13 :
Total Pages : 1716 pages
Book Rating : 4.:/5 (42 download)

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Book Synopsis Energy and Water Development Appropriations for 1983 by : United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development

Download or read book Energy and Water Development Appropriations for 1983 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development and published by . This book was released on 1982 with total page 1716 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Energy and Water Development Appropriations for 1982: Department of Energy budget justifications

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Author :
Publisher :
ISBN 13 :
Total Pages : 1704 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Energy and Water Development Appropriations for 1982: Department of Energy budget justifications by : United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development

Download or read book Energy and Water Development Appropriations for 1982: Department of Energy budget justifications written by United States. Congress. House. Committee on Appropriations. Subcommittee on Energy and Water Development and published by . This book was released on 1981 with total page 1704 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drugs—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464990891
Total Pages : 1195 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Drugs—Advances in Research and Application: 2012 Edition by :

Download or read book Drugs—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 1195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drugs—Advances in Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Drugs. The editors have built Drugs—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drugs in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Drugs—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Heterocyclic Chemistry

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Publisher : Academic Press
ISBN 13 : 0124046436
Total Pages : 313 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Advances in Heterocyclic Chemistry by : Alan R. Katritzky

Download or read book Advances in Heterocyclic Chemistry written by Alan R. Katritzky and published by Academic Press. This book was released on 2012-12-25 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties. - Provides up-to-date material on a fast-growing and highly topical subject area - Contains the latest research covering a wide variety of heterocyclic topics - Written by leading authorities and designed as a handbook for students and industry and academic researchers

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

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Publisher : Elsevier
ISBN 13 : 0443161674
Total Pages : 699 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal Banik

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Banik and published by Elsevier. This book was released on 2024-05-31 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. - Highlights the need for adoption of sustainable and green chemistry pathways in drug development - Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these - Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Solvent-Free Methods in Nanocatalysis

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Publisher : John Wiley & Sons
ISBN 13 : 3527348743
Total Pages : 357 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Solvent-Free Methods in Nanocatalysis by : Rafael Luque

Download or read book Solvent-Free Methods in Nanocatalysis written by Rafael Luque and published by John Wiley & Sons. This book was released on 2023-04-10 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solvent-Free Methods in Nanocatalysis Discover solvent-free approaches for the synthesis of nanocatalysts as well as various catalytic transformations in this unique one-stop resource Solvent-free methods have attracted wide attention in organic synthesis and catalysis as a promising approach towards “greener” and more sustainable chemical transformations. In this regard, nanocatalysis has seen particular growth in recent years. Solvent-Free Methods in Nanocatalysis gives an in-depth overview of nanocatalysts and their catalytic applications using solvent-free methods. After a brief introduction, it covers various synthetic techniques for the preparation of nanocatalysts and supports using solvent-free methods, e.g. ball-milling, microwave- and plasma-assisted methods. The book discusses in detail different catalyst classes, such as metal oxides, doped and functionalized nanocarbons, as well as nitride- and silica-based materials to help researchers to understand the efficiency and nature of these catalysts/supports based on their chemical structure. In the book readers will also find: A brief account of the history, challenges, and recent advances in the field Detailed discussion of advantages and disadvantages of solvent-free techniques for nanocatalyst preparation Treatment of important solvent- and catalyst-free organic transformations (i.e. oxidation, coupling and multicomponent reactions) A chapter on supported ionic liquids for solvent-free catalysis Written by leading researchers in the field, Solvent-Free Methods in Nanocatalysis is a useful reference for researchers and students working in organic synthesis, catalysis, and nanomaterials science.

Microscopy Applied to Materials Sciences and Life Sciences

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Author :
Publisher : CRC Press
ISBN 13 : 1351251570
Total Pages : 502 pages
Book Rating : 4.3/5 (512 download)

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Book Synopsis Microscopy Applied to Materials Sciences and Life Sciences by : Ajay Vasudeo Rane

Download or read book Microscopy Applied to Materials Sciences and Life Sciences written by Ajay Vasudeo Rane and published by CRC Press. This book was released on 2018-11-21 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume, Microscopy Applied to Materials Sciences and Life Sciences. focuses on recent theoretical and practical advances in polymers and their blends, composites, and nanocompos¬ites related to their microscopic characterization. It highlights recent accomplishments and trends in the field of polymer nanocomposites and filled polymers related to microstructural characterization. This book gives an insight and better understanding into the development in microscopy as a tool for characterization. The book emphasizes recent research work in the field of microscopy in life sciences and materials sciences mainly related to its synthesis, characterizations, and applications. The book explains the application of microscopic techniques in life sciences and materials sciences, and their applications and state of current research carried out. The book aims to foster a better understanding of the properties of polymer composites by describing new techniques to measure microstructure property relationships and by utilizing techniques and expertise developed in the conventional filled polymer composites. Characterization techniques, particularly microstructural characterization, have proven to be extremely difficult because of the range of length-scales associated with these materials. Topics include: •Instrumentation and Techniques: advances in scanning probe microscopy, SEM, TEM, OM. 3D imaging and tomography, electron diffraction techniques and analytical microscopy, advances in sample preparation techniques in-situ microscopy, correlative microscopy in life and material sciences, low voltage electron microscopy. •Life Sciences: Structure and imaging of biomolecules, live cell imaging, neurobiology, organelles and cellular dynamics, multi-disciplinary approaches for medical and biological sciences, microscopic application in plants, microorganism and environmental science, super resolution microscopy in biological sciences. •Materials Sciences: materials for nanotechnology, metals alloys and inter-metallic, ceramics, composites, minerals and microscopy in cultural heritage, thin films, coatings, surfaces and interfaces, carbon based materials, polymers and soft materials and self-assembled materials, semiconductors and magnetic materials. Polymers and inorganic nanoparticles. The volume will be of significant interest to scientists working on the basic issues surrounding polymers, nanocomposites, and nanoparticulate-filled polymers, as well as those working in industry on applied problems, such as processing. Because of the multidisciplinary nature of this research, the book will be valuable to chemists, materials scientists, physicists, chemical engineers, and processing specialists who are involved and interested in the future frontiers of blends.