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New Developments In Antirheumatic Therapy
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Book Synopsis New Developments in Antirheumatic Therapy by : K. D. Rainsford
Download or read book New Developments in Antirheumatic Therapy written by K. D. Rainsford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g. ,),-interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy closporin A and low-dose methotrexate in the therapy of rheumatoid arth ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.
Book Synopsis Advances in Anti Rheumatic Therapy by : Kim D. Rainsford
Download or read book Advances in Anti Rheumatic Therapy written by Kim D. Rainsford and published by CRC Press. This book was released on 1995-12-11 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work on advances in anti-rheumatic therapy covers topics such as: outcome measures in clinical trials of anti-rheumatic drugs; azapropazone (AZP); the mode of action of glucocorticoids; and clinical trials of oral chondroitin sulphate in the treatment of osteoarthritis.
Book Synopsis Antirheumatic Therapy: Actions and Outcomes by : Richard O. Day
Download or read book Antirheumatic Therapy: Actions and Outcomes written by Richard O. Day and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our goal for this book is to examine the contemporary therapy of rheumatoid arthritis (RA) from the increasingly important perspective of impact upon quality of life, costs and long-term health outcomes. For too long the focus has been on short term, symptomatic, and surrogate indicator outcomes. Yet RA is a life-long disor der with the majority of impact on an individual patient many years following onset. Further, even in the short-term, researchers and rheumatologists have tended to emphasize measurements of disease activity such as joint counts, ESR and physi cian's opinion as to the amount of disease activity present. It is only relatively recently that measures of structural damage, quality of life and impact on broad domains of health have been given increasing emphasis. Also, the significance of early treatment of RA in order to optimise long-term outcomes has a relatively short history [1]. We have been focussed on the disease processes as surrogates for long term outcomes. Until the short-term process measures are validated as surrogates of long-term effects we should also turn our attention to outcomes of disease and the impact of our management on those outcomes [2). Inour view, this book is especially timely. We are at the dawn of a revolution in the management of RA and other complex immunological inflammatory disorders because their molecular, genetic and environmental mechanisms are being unrav elled. Inthe process, we are revealing a substantial number of novel and significant targets for pharmacotherapy.
Book Synopsis New developments in the treatment of chronic rheumatoid arthritis by :
Download or read book New developments in the treatment of chronic rheumatoid arthritis written by and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fast Facts: Rheumatoid Arthritis by : John D. Isaacs
Download or read book Fast Facts: Rheumatoid Arthritis written by John D. Isaacs and published by Karger Medical and Scientific Publishers. This book was released on 2011-05-01 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly updated second edition of 'Fast Facts: Rheumatoid Arthritis' provides an easy-to-read overview of how the condition is thought to develop and how it is diagnosed, monitored and treated. Written by two leading UK and US rheumatologists, it covers the many recent developments in this field, including: • Recently published classification criteria • The emerging role of anti-CCP autoantibodies • The latest developments in ultrasound and MRI • The association between RA and cardiovascular disease and lung disease • New concepts of undifferentiated arthritis and treatment to remission • The importance of early referral and new biological therapies 'Fast Facts: Rheumatoid Arthritis' provides a well-referenced international perspective on this condition. It is a 'must read' for all healthcare professionals caring for patients with this debilitating inflammatory joint disease. Contents: • The normal joint • Etiology • Pathogenesis • Epidemiology • Clinical features • Investigation • Assessment • Management - traditional measures • Management - biological therapies • Therapeutic developments
Book Synopsis Biologics for the Treatment of Rheumatoid Arthritis by : Ronald van Vollenhoven
Download or read book Biologics for the Treatment of Rheumatoid Arthritis written by Ronald van Vollenhoven and published by Springer. This book was released on 2015-12-22 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.
Book Synopsis Therapeutic Control of Inflammatory Diseases by : Ivan Otterness
Download or read book Therapeutic Control of Inflammatory Diseases written by Ivan Otterness and published by Lippincott Williams & Wilkins. This book was released on 1986 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Therapies in the Field of Rheumatology by : Maria Gerosa
Download or read book New Therapies in the Field of Rheumatology written by Maria Gerosa and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the long term prognosis of patients with rheumatic disease has dramatically improved, due to the enormous advances in the understanding of the pathogenesis of these diseases that have led to the development of drugs targeting the molecules directly involved in the inflammatory response. The development of these biological drugs has radically changed the therapeutic approach of inflammatory rheumatic diseases, mainly in patients resistant to standard treatment. Also in the field of conventional therapy, many new data have confirmed the effectiveness of "old" drugs, such as hydroxychloroquine, methotrexate and azathioprine, demonstrating several additional beneficial properties for the treatment of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) or other autoimmune diseases. Moreover, immunosuppressant developed to prevent graft rejection such as mycophenolate or tacrolimus have been demonstrated to have an important role in the treatment of rheumatic patients. Beside the well defined anti-inflammatory properties of biological and synthetic anti-rheumatic drugs, a number of additional beneficial effects have been suggested, that have been hypothesized to prevent long term complications of autoimmune diseases, such as accelerated atherosclerosis, increased cardiovascular risk and osteoporosis. This Research Topic collects new information regarding safety and effectiveness of new and old drugs for the treatment of RA, SLE, or other autoimmune diseases.
Book Synopsis Contemporary Targeted Therapies in Rheumatology by : Josef S. Smolen
Download or read book Contemporary Targeted Therapies in Rheumatology written by Josef S. Smolen and published by CRC Press. This book was released on 2007-10-18 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the pathogenesis of rheumatic diseases.Along with the clinical success of some of these targeted approaches, new information has been generated from their application concerning the pathophysiologic mechanisms underlying rheumatic diseases and, as a result, new targets have been identified.The ongoing dialogue between basic scientists, clinical investigators, metrologists and clinicians remains an essential component for the further development, refinement, integration and optimization of targeted therapies of the rheumatic diseases. The goal of this volume is to provide comprehensive, up to date information on all aspects of the rapidly evolving development of targeted therapies of the rheumatic diseases to foster further advances to improve therapy of patients with these conditions. Targeted Therapies in Rheumatology established itself as an excellent reference for all those needing to know about the clinical implications of new drugs and developments for patients suffering from rheumatoid arthritis. This volume takes up the further developments that have occurred in several of the drug therapies covered in the first volume, as well as looking at the latest areas of promising research.
Book Synopsis New Directions in Antirheumatic Therapy by : David E. Trentham
Download or read book New Directions in Antirheumatic Therapy written by David E. Trentham and published by . This book was released on 1989 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis New Directions in Antirheumatic Therapy by : David E. Trentham
Download or read book New Directions in Antirheumatic Therapy written by David E. Trentham and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Rheumatology Update by : Indonesian Rheumatology Association
Download or read book Rheumatology Update written by Indonesian Rheumatology Association and published by . This book was released on 1986 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Management of Rheumatic Disorders by : J. M. H. Moll
Download or read book Management of Rheumatic Disorders written by J. M. H. Moll and published by Springer. This book was released on 1983 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Historical background.- 2. General therapeutic factors and principles.- 3. Communication: the basis of management.- 4. Drug therapy (1): general aspects.- 5. Drug therapy (2): non-specific drugs.- 6. Drug therapy (3): 'specific' drugs.- 7. Local injection therapy.- 8. Radiotherapy.- 9. Orthopaedic surgery.- 10. Rehabilitation.- 11. Heterodox procedures.- 12. General summary and conclusions, including new developments and future prospects.
Book Synopsis Advances in Anti-Rheumatic Therapy by : Kim D Rainsford
Download or read book Advances in Anti-Rheumatic Therapy written by Kim D Rainsford and published by CRC Press. This book was released on 2022-02-03 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1996: This work on advances in anti-rheumatic therapy covers topics such as: outcome measures in clinical trials of anti-rheumatic drugs; azapropazone (AZP); the mode of action of glucocorticoids; and clinical trials of oral chondroitin sulphate in the treatment of osteoarthritis.
Book Synopsis Biologics in Rheumatology by : Coziana Ciurtin
Download or read book Biologics in Rheumatology written by Coziana Ciurtin and published by . This book was released on 2016 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has been acquired in the treatment of rheumatic conditions with the introduction of biologic therapies, which has enabled better control of disease activity and improved patients' long-term outcome. Apart from several biologic treatments already licensed for use in autoimmune rheumatic conditions, numerous other agents are currently under investigation. This rapid expansion of the therapeutic armamentarium requires a critical analysis of individual biologic options and their clinical indications, in order to facilitate the optimal use of these new therapies. The authors felt that a comprehensive book revisiting all the evidence available regarding the efficacy, cost-effectiveness and health implications of the use of biologics in rheumatology was needed in order to integrate the clinical, ethical and socio-economic aspects related to their use. This book is aimed at specialist doctors, trainees, nurses and health professionals working in the field of rheumatology. It critically appraises the level of evidence behind the use of biologic agents in diverse autoimmune diseases, comprising separate chapters which focus on rheumatoid arthritis, systemic lupus erythematosus, myositis, systemic sclerosis, Sjogren's syndrome, seronegative spondyloarthropathies, psoriatic arthritis and psoriasis, small, medium and large vessel vasculitis, osteoporosis, and interstitial lung disease associated with rheumatic conditions. In addition, the book explores aspects related to the use of biologic agents, such as ethical considerations of consenting patients to take part in clinical trials with biologics, and adolescent and adult rheumatology nurse perspectives related to patients' benefits of biologic therapies. Particular interest is given to the use of biologics during pregnancy and assessment of their infectious risks. A separate chapter explores the off-target benefits associated with the use of anti-TNF therapies. Several chapters include data about cost-effectiveness, and national and international guidelines for the use of biologic agents in different rheumatic conditions.
Book Synopsis Recent Developments in Anti-Inflammatory Therapy by : Parteek Prasher
Download or read book Recent Developments in Anti-Inflammatory Therapy written by Parteek Prasher and published by Academic Press. This book was released on 2023-02-17 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. Identifies recent developments and current trends in anti-inflammation therapy Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies Contains a blend of editors from both academia and industry
Book Synopsis Side-Effects of Anti-Inflammatory Drugs 3 by : K. D. Rainsford
Download or read book Side-Effects of Anti-Inflammatory Drugs 3 written by K. D. Rainsford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contents of this book represent papers which were presented at the Third International Meeting on "Side-Effects of Anti-Inflammatory and Analgesic Drugs" which was held under the auspices of the University of Verona, Institute of Pharmacology in Verona on 8-11 May 1991. This meeting was held in conjunction with the 13th European Workshop on Inflammation and although publications from this part of the meeting are not published here (they appear in Agents and Actions), we were fortunate in having a group of people interested in inflammation from varying backgrounds. The success of the third meeting followed previous meetings held in Cambridge and Verona respectively and continue a tradition which has now become well established. The meeting brought together physicians, scientists and those concerned with the production and use of anti-inflammatory drugs to a very stimulating conference to discuss basic issues affecting all aspects of side-effects of anti-inflammatory and analgesic drugs as well as their detection and treatment. The meeting was held in the Auditorium of Glaxo Italy and we are very grateful to that company for use of their facilities as well as to the University of Verona, Institute of Pharmacology, for valuable secretarial and administrative help. The success of the conference would not have been possible without valuable financial assistance of the companies listed separately (under Acknowledgements) as well as to the organizers of the 13th European Workshop on Inflammation who collaborated with us.
