New Antibiotic Targets

Download New Antibiotic Targets full books in PDF, epub, and Kindle. Read online New Antibiotic Targets ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

New Antibiotic Targets

Author : W. Scott Champney
Publisher : Springer Science & Business Media
ISBN 13 : 1588299155
Total Pages : 274 pages
Book Rating : 4.5/5 (882 download)

DOWNLOAD NOW!

Book Synopsis New Antibiotic Targets by : W. Scott Champney

Download or read book New Antibiotic Targets written by W. Scott Champney and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. The book will provide laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

Treating Infectious Diseases in a Microbial World

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309180686
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council

Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Drug Discovery Targeting Drug-Resistant Bacteria

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128184809
Total Pages : 432 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Drug Discovery Targeting Drug-Resistant Bacteria by : Prashant Kesharwani

Download or read book Drug Discovery Targeting Drug-Resistant Bacteria written by Prashant Kesharwani and published by Academic Press. This book was released on 2020-05-29 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Antibiotics

Author : Claudio O. Gualerzi
Publisher : John Wiley & Sons
ISBN 13 : 3527659706
Total Pages : 549 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!

Book Synopsis Antibiotics by : Claudio O. Gualerzi

Download or read book Antibiotics written by Claudio O. Gualerzi and published by John Wiley & Sons. This book was released on 2013-09-05 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.

Technological Challenges in Antibiotic Discovery and Development

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309298172
Total Pages : 82 pages
Book Rating : 4.3/5 (92 download)

DOWNLOAD NOW!

Book Synopsis Technological Challenges in Antibiotic Discovery and Development by : National Research Council

Download or read book Technological Challenges in Antibiotic Discovery and Development written by National Research Council and published by National Academies Press. This book was released on 2014-01-27 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.

Antibiotic Discovery and Development

Author : Thomas J. Dougherty
Publisher : Springer Science & Business Media
ISBN 13 : 1461414008
Total Pages : 1119 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!

Book Synopsis Antibiotic Discovery and Development by : Thomas J. Dougherty

Download or read book Antibiotic Discovery and Development written by Thomas J. Dougherty and published by Springer Science & Business Media. This book was released on 2011-12-18 with total page 1119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.

Mechanisms of antibiotic resistance

Author : Jun Lin
Publisher : Frontiers Media SA
ISBN 13 : 2889195260
Total Pages : 226 pages
Book Rating : 4.8/5 (891 download)

DOWNLOAD NOW!

Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin

Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Antibiotics

Author : Sergio Sánchez
Publisher : Caister Academic Press Limited
ISBN 13 : 9781908230546
Total Pages : 0 pages
Book Rating : 4.2/5 (35 download)

DOWNLOAD NOW!

Book Synopsis Antibiotics by : Sergio Sánchez

Download or read book Antibiotics written by Sergio Sánchez and published by Caister Academic Press Limited. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 'golden age' for antibiotic discovery, from 1940 until the early 1970s, ushered in a new era in human- and animal-health and the associated dramatic increase in human life expectancies. Indeed, the possibility of eradicating infectious disease seemed feasible. However, it soon became apparent that microorganisms wouldn't be defeated so easily. Their weapon: antibiotic resistance. Today, microbial antibiotic resistance is rapidly exhausting the supply of effective compounds, and this makes the possibility of a global public health disaster seem likely. The urgency of this situation has spawned a plethora of new multi-disciplinary research initiatives looking for novel antibiotics and other antimicrobial agents. In this timely book, respected international experts summarize the most important research to provide a timely overview of the field. Opening chapters define 'antibiotic,' explain why we need new compounds, outline the applications of antibiotics, both old and new, and describe the producing microbes. These are followed by chapters that cover antibiotic resistance, toxicity, overuse, new antimicrobial sources, new targets, novel technologies for antibiotic discovery (e.g. silent gene clusters), lantibiotics, natural antivirals, new macrolide derivatives, and antibiotics in the pipeline. The book will be essential reading for everyone working in antimicrobial research, biotechnology companies, and the pharmaceutical industry, and it is recommended for all microbiology libraries. [Subject: Microbiology, Life Science, Medicine]

How to Overcome the Antibiotic Crisis

Author : Marc Stadler
Publisher : Springer
ISBN 13 : 3319492845
Total Pages : 497 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis How to Overcome the Antibiotic Crisis by : Marc Stadler

Download or read book How to Overcome the Antibiotic Crisis written by Marc Stadler and published by Springer. This book was released on 2016-12-21 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.

Breaching Barriers

Author : Alexandra Sophia Antonoplis
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Breaching Barriers by : Alexandra Sophia Antonoplis

Download or read book Breaching Barriers written by Alexandra Sophia Antonoplis and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of antibiotic-resistant bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE), necessitates the development of new therapeutics. Antibiotic resistance can result in life-threatening infections, where resistant bacteria are able to proliferate in the presence of high concentrations of antibiotic due to mechanisms such as efflux and enzymatic deactivation. An additional phenomenon which can cause recalcitrant infection is antibiotic persistence. Persistent bacterial cells withstand antibiotic treatment by entering a dormant or slow-growing state in response to cellular stress and are often found within biofilms, which are communities of bacteria enmeshed in a self-produced extracellular matrix. Most clinically used antibiotics target metabolically active bacteria and are largely ineffective against biofilms and other persistent bacterial populations. Innovative therapeutic strategies are needed to treat both resistant and persistent bacteria, and this dissertation describes the development and characterization of new chemical approaches to target these pathogens. Our studies were inspired by the ability of uropathogenic E. coli (UPEC), the most common causative agent of urinary tract infection (UTI), to contribute to chronic infection via several mechanisms, including robust adhesion to bladder epithelial cells and formation of intracellular biofilms. We first investigated the molecular determinants of UPEC adhesion to bladder cells using a model mammalian cell culture system, enabling the identification and development of new strategies to prevent bacterial adhesion. We also investigated the ability of conventional antibiotics to treat intracellular UPEC, which motivated the use of cell-penetrating, guanidinium-rich molecular transporters (GR-MoTrs) to improve delivery of antibiotics to intracellular pathogens. We prepared and evaluated a series of antibiotic-GR-MoTr conjugates to treat UPEC, focusing on the glycopeptide class of antibiotics, which are unable to cross mammalian or bacterial cell membranes. While our antibiotic-transporter conjugates exhibited no activity against UPEC, we discovered a vancomycin-oligoarginine conjugate (V-r8) that exhibited extraordinary activity against MRSA biofilms and persister cells. We investigated its mechanism of action and observed rapid cell killing and enhanced cellular association as a result of covalent conjugation of vancomycin to octaarginine. Together with demonstrating its remarkable activity in eradicating biofilm-associated bacteria in a mouse wound infection model, we also generated testable hypotheses for the molecular-level mode of action of V-r8, consistent with all of our biochemical data. In parallel, we screened other glycopeptide conjugates in an effort to target UPEC, where we discovered a vancomycin-arginine conjugate (V-R) effective against UPEC and CRE. The V-R derivative appeared to access intracellular cell-wall targets and served to disrupt bacterial cell-wall synthesis. Our studies inform future antibiotic development efforts for difficult-to-treat bacterial populations and highlight the utility of conjugating antibiotics to GR-MoTrs to generate potent therapeutics with new activity and efficacy.

Improving Food Safety Through a One Health Approach

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309259363
Total Pages : 418 pages
Book Rating : 4.3/5 (92 download)

DOWNLOAD NOW!

Book Synopsis Improving Food Safety Through a One Health Approach by : Institute of Medicine

Download or read book Improving Food Safety Through a One Health Approach written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-10 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Antibiotic Drug Resistance

Author : José-Luis Capelo-Martínez
Publisher : John Wiley & Sons
ISBN 13 : 1119282527
Total Pages : 730 pages
Book Rating : 4.1/5 (192 download)

DOWNLOAD NOW!

Book Synopsis Antibiotic Drug Resistance by : José-Luis Capelo-Martínez

Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Antibiotic Drug Discovery

Author : Steven M Firestine
Publisher : Royal Society of Chemistry
ISBN 13 : 178801149X
Total Pages : 289 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis Antibiotic Drug Discovery by : Steven M Firestine

Download or read book Antibiotic Drug Discovery written by Steven M Firestine and published by Royal Society of Chemistry. This book was released on 2017-05-19 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a resurgence of antibiotic drug discovery. This book brings together the relevant information to assess the state-of-the-art. It identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities. Addressing the need for continued investment in antibiotic drug development, the book provides a point of reference for the rapidly expanding infectious disease research community. In addition to its attention on new targets, the book focusses on the medicinal chemistry and chemistry of the targets. Within this framework, chapters from leading researchers in academia and industry address findings in important areas such as biofilm production, narrow spectrum antibiotics and novel antibacterials from previously uncultured soil bacteria. This book will be a useful resource for postgraduate students and researchers in medicinal chemistry wishing to understand the latest approaches to antibiotic drug discovery.

Antibiotic Drug Discovery Targeting Bacterial Metabolism

Author : Miranda J Wallace
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (131 download)

DOWNLOAD NOW!

Book Synopsis Antibiotic Drug Discovery Targeting Bacterial Metabolism by : Miranda J Wallace

Download or read book Antibiotic Drug Discovery Targeting Bacterial Metabolism written by Miranda J Wallace and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last century, the use of antibiotics has enabled many advances in modern medicine, making life as we know it possible. In recent years, however, emerging bacterial resistance to virtually all major antibiotic classes has resulted in a worldwide increase in morbidity, mortality, and financial burden associated with drug resistant infections. The antimicrobial resistance crisis presents an urgent need for new antimicrobials with distinct mechanisms of action from existing drugs. The current pharmaceutical pipeline of new antibiotics is limited due to three obstacles: a lack of understanding of resistance mechanisms, a dearth of novel mechanisms of action among new antibiotics, and drug discovery challenges unique to bacteria due to their cellular and physiological composition. My dissertation research addressed each of these challenges. The mechanisms of resistance to folate biosynthesis inhibitors in Staphylococcus aureus were explored from a genetic, biological, biochemical, and structural basis. Unexpected roles in resistance and fitness were attributed to various mutations in the sulfonamide target dihydropteroate synthase. This information currently guides the development of next-generation antifolates designed to avoid these characterized resistance strategies. In the subsequent chapter, a conditional metabolic screening approach was employed to discover inhibitors disrupting metabolic pathways related to folate biosynthesis. The testing conditions were optimized to measure the biological activity of antimetabolites, which is often masked by nutrients present in standard testing media. This screen yielded an inhibitor of cysteine synthase A in Escherichia coli, which was characterized in chapter four. Multiple experimental approaches yielded indications that the cysteine synthase A inhibitors have a false-product mechanism, resulting in a widespread impact on several key branches of metabolism beyond cysteine biosynthesis. The final research chapter describes the adaptation of the cellular thermal shift assay to explore target engagement in the Gram-negative cell system. Drug entry and accumulation are especially challenging to achieve in Gram-negative cells due to their unique dual membrane system and associated efflux machinery. This assay provided an early stage tool to quickly assess the ability of antimicrobial candidates to engage the intended target in the intact cell system and also measure efflux sensitivity. Taken together, this dissertation contributes to the fight against the antimicrobial resistance crisis from multiple angles, all within the context of bacterial metabolism which is a rich source of exciting new antibiotic targets.

The Microbes Fight Back

Author : Laura Bowater
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014111
Total Pages : 302 pages
Book Rating : 4.7/5 (88 download)

DOWNLOAD NOW!

Book Synopsis The Microbes Fight Back by : Laura Bowater

Download or read book The Microbes Fight Back written by Laura Bowater and published by Royal Society of Chemistry. This book was released on 2017-10-25 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics are familiar drugs to us all, so familiar that we may take them for granted. They allow us to survive life-threatening infections, and allow us to protect the animals we farm for food. Many antibiotics have now become ineffective against common diseases, and there are few alternative treatments to replace them. In this topical popular science book, Laura Bowater, Professor of Microbiology Education and Engagement at Norwich Medical School, considers the past, present and uncertain future of antibiotics. This book begins by looking back at how infectious diseases, such as smallpox and the plague, were able to wreak havoc on populations before the discovery of the first antibiotics. These then revolutionised the medical world. In an engaging and accessible style, Professor Bowater takes the reader through how antibiotics are made, how bacteria are able to mutate and develop resistance and she explains why there is now a lack of new antibiotic drugs coming to market. What will a future of continued antibiotic resistance look like? How can human activities prevent the rise of ‘superbugs'? Professor Bowater highlights the need for universal cooperation in order to tackle this global health challenge, which, if not addressed, could transport us back to the medical dark ages.

Antibiotic Drug Discovery

Author : Steven M. Firestine
Publisher : Royal Society of Chemistry
ISBN 13 : 1782624244
Total Pages : 289 pages
Book Rating : 4.7/5 (826 download)

DOWNLOAD NOW!

Book Synopsis Antibiotic Drug Discovery by : Steven M. Firestine

Download or read book Antibiotic Drug Discovery written by Steven M. Firestine and published by Royal Society of Chemistry. This book was released on 2017-05-30 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities.

The Evolving Threat of Antimicrobial Resistance

Author : World Health Organization
Publisher :
ISBN 13 : 9789241503181
Total Pages : 0 pages
Book Rating : 4.5/5 (31 download)

DOWNLOAD NOW!

Book Synopsis The Evolving Threat of Antimicrobial Resistance by : World Health Organization

Download or read book The Evolving Threat of Antimicrobial Resistance written by World Health Organization and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.