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Neurothrombectomie
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Book Synopsis Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke by :
Download or read book Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute ischemic strokes are associated with poor outcomes and high healthcare burden. In patients with occlusions of large cerebral vessels, patients with high baseline stroke severity scores as defined by the National Institute of Health Stroke Score (NIHSS), and patients unlikely to benefit or having failed treatment with intravenous (IV) recombinant tissue plasminogen activator (rtPA), there is a need for alternative methods of revascularization which can improve outcomes without increasing the risk for intracranial hemorrhage. The uses of various neurothrombectomy devices (clot retrievers, aspiration/suction devices, snare-like devices, ultrasonography technologies, and lasers) have been examined in these populations. Currently, two neurothrombectomy devices are FDA-cleared through the FDA 510(k) process: the MERCI clot retriever and the Penumbra System. Various ongoing clinical trials are currently evaluating the impact of these devices, as well as other (off-label) neurothrombectomy devices, for the treatment of acute ischemic stroke. The goal of this technical brief is to describe neurothrombectomy devices currently being used or actively investigated in the treatment of patients with acute ischemic stroke and to summarize the evidence supporting their use.
Author :U. S. Department of Health and Human Services Publisher :Createspace Independent Pub ISBN 13 :9781484934401 Total Pages :102 pages Book Rating :4.9/5 (344 download)
Book Synopsis Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke by : U. S. Department of Health and Human Services
Download or read book Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke written by U. S. Department of Health and Human Services and published by Createspace Independent Pub. This book was released on 2013-05-09 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is the third leading cause of death following diseases of the heart and cancer. A majority of strokes are classified as ischemic in nature (87%), with intracerebral hemorrhagic (10 percent) and subarachnoid hemorrhagic stroke (3%) accounting for the rest. Every year in the U.S., approximately 795,000 people develop a new or recurrent stroke, with 610,000 first attacks and 185,000 recurrent attacks. The annual rate of strokes is expected to increase to 1.2 million cases by the year 2025, a troubling trend that underlines the urgency of adequate ischemic stroke treatment. Stroke occurs more commonly in females than males, especially at older ages. Blacks have a two-fold higher risk of first-ever stroke than Caucasians, with age-adjusted incidences of 6.6 per 1000 in black men as compared with 3.6 per 1000 in Caucasian men. In 2006, 43.6 deaths occurred due to stroke per 100,000 people in the U.S., averaging out to one death due to stroke every 3 to 4 minutes. In 2005, the overall mortality rate from stroke was approximately 44.7 per 100,000 for Caucasian males, 70.5 per 100,000 for black males, 44.0 per 100,000 for Caucasian females, and 60.7 per 100,000 for black females. Lower mortality rates were seen in Hispanic, Asian, and American Indian populations as compared with Caucasian populations. Stroke is the leading cause of long-term disability in the U.S. Thirty percent of stroke survivors require outpatient rehabilitation services and 15 to 30% of patients remain permanently disabled. Significant decreases in health-related quality-of-life are also seen following a stroke. Studies have shown that at-risk patients view the consequences of experiencing an ischemic stroke as being worse than death. Additionally, evidence has demonstrated the significant impact of ischemic stroke on caregiver burden and quality-of-life in caregivers. The goal of this technical brief is to describe neurothrombectomy devices currently being used or actively investigated in the treatment of patients with acute ischemic stroke, and to summarize the evidence supporting their use. This technical brief is based on a systematic scan of the literature. Key questions, methods, and approaches were defined by the University of Connecticut/Hartford Hospital Evidence-based Practice Center after discussions with representatives from the Agency for Healthcare Research and Quality and clinical content and technical experts. Key Questions addressed in this review include: KQ1. What are the different types of neurothrombectomy devices in use or in development for treatment of acute ischemic stroke? 1a. What are the existing FDA indications for each device? 1b. Which devices are being used off-label for this indication? 1c. What is the status of FDA approval for each device? 1d. What are the theoretical advantages and disadvantages of these devices compared to other treatment options? 1e. What are the potential safety issues and harms associated with the use of these devices? 1f. What is the extent of utilization of the different devices? KQ2. From a systematic scan of studies of different types of neurothrombectomy devices, what are the type(s) of devices, study designs and sizes, patient characteristics, comparators used in comparative studies, lengths of follow-up, concurrent or prior therapies, outcomes measured, and adverse events, harms, and safety issues reported? 2a. Type(s) of devices 2b. Study design and size 2c. Patient characteristics 2d. Comparator used in comparative studies 2e. Length of follow-up 2f. Concurrent or prior therapy 2g. Outcomes measured 2h. Adverse events, harms and safety issues reported KQ3. What are the variables associated with use of the devices that may impact outcomes (e.g. time to deployment, training/expertise of interventionalist, location of infarct, concurrent therapies)?
Book Synopsis Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke [Internet] by : William L. Baker
Download or read book Neurothrombectomy Devices for Treatment of Acute Ischemic Stroke [Internet] written by William L. Baker and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stroke: New Insights for the Healthcare Professional: 2013 Edition by :
Download or read book Stroke: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Stroke: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Stroke: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis The Role of the Plasminogen Activating System in Neurobiology by : Robert L. Medcalf
Download or read book The Role of the Plasminogen Activating System in Neurobiology written by Robert L. Medcalf and published by Frontiers Media SA. This book was released on 2017-01-13 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ebook contains a series of original publications, reviews and mini-reviews by leaders in the field that address the growing importance of the plasminogen activating system in neurobiology. The articles included cover the role of the plasminogen activating system as a key modulator of blood brain barrier permeability, and the implications of this in traumatic brain injury and in ischemic stroke. State-of-the-Art manuscripts are also included that address the regulatory mechanisms that control this important process.
Book Synopsis Medical Devices by : Prakash Srinivasan Timiri Shanmugam
Download or read book Medical Devices written by Prakash Srinivasan Timiri Shanmugam and published by CRC Press. This book was released on 2022-10-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the wide variety of medical devices that are an integral part of clinical practice, this practical book includes descriptions of medical devices by both clinical specialty and purpose, thus ensuring that a wide variety of devices are included. Covering important elements such as body contact, duration of contact, the mechanism of each device, its intended use, single and/or multiple use, benefits and any side/adverse/toxicological effects to the patient, and how to avoid user error, and authored by clinicians, researchers and educators who are experienced in medical device use, regulation and research, the content will be of benefit to postgraduate clinicians and employees of medical device companies.
Book Synopsis Physical Therapy Case Files: Acute Care by : Erin E. Jobst
Download or read book Physical Therapy Case Files: Acute Care written by Erin E. Jobst and published by McGraw Hill Professional. This book was released on 2013-04-05 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: SHARPEN YOUR CRITICAL THINKING SKILLS AND PREPARE FOR REAL-WORLD PRACTICE WITH CLINICAL CASES New in the authoritative Case Files series, Physical Therapy Case Files: Acute Care gives you case studies that illustrate critical concepts you need to build and enhance your skills in physical therapy. Each case includes a discussion of the health condition, examination, evaluation, diagnosis, plan of care andinterventions, evidence-based practice recommendations, andreferences. NPTE-style review questions accompanying eachcase reinforce your learning. With Physical Therapy Case Files: Acute Care, everything you need to succeed in the clinic and on the NPTE is right here in your hands. 31 acute-care cases with National Physical Therapy Examination-style review questions help you learn best practices in the context of patient care Enhance your practice with evidence-based cases written by leading clinicians, researchers, and academics Includes evidence-based ratings for examination and treatment plans Perfect for coursework use and NPTE preparation
Book Synopsis Issues in Neurological Surgery and Specialties: 2011 Edition by :
Download or read book Issues in Neurological Surgery and Specialties: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 3017 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Neurological Surgery and Specialties: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Neurological Surgery and Specialties. The editors have built Issues in Neurological Surgery and Specialties: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neurological Surgery and Specialties in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Neurological Surgery and Specialties: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Advances in Neurologic Therapy, An issue of Neurologic Clinics by : Jose Biller
Download or read book Advances in Neurologic Therapy, An issue of Neurologic Clinics written by Jose Biller and published by Elsevier Health Sciences. This book was released on 2013-08-28 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurologic Clinics features a review of the latest therapeutic developments in common and less common neurologic disorders and includes the following articles: Latest Data on Platelet Antiaggregants in Stroke Prevention; New Anticoagulants for Atrial Fibrillation Stroke Prevention; Unanswered Questions in Thrombolytic Therapy for Acute Ischemic Stroke; New Strategies for Endovascular Recanalization of Acute Ischemic Stroke; New Developments in the Treatment of Intracerebral Hemorrhage. What is in the horizon?; New Therapies for Unruptured Intracranial Aneurysms; New and Emergency Therapies for Arteriovenous Malformations; Advances and Controversies in the Management of Cerebral Venous Thrombosis in Adults; Epilepsy: Neurostimulation and New Drug Targets; Surgical Treatment of Parkinson's Disease; Deep Brain Stimulation (DBS) in Non-Parkinsonian Movement Disorders and Emerging Technologies, Targets and Therapeutic Promises in DBS; Multiple Sclerosis. New and Emerging Therapies; Advances in the Medical Management of Myasthenia Gravis; Update in the Treatment of Primary Brain Tumors; and Immunotherapy for Alzheimer’s Disease.
Book Synopsis Clinical and Translational Science by : David Robertson
Download or read book Clinical and Translational Science written by David Robertson and published by Academic Press. This book was released on 2016-11-25 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs
Book Synopsis Acute Ischemic Stroke by : R. Gilberto González
Download or read book Acute Ischemic Stroke written by R. Gilberto González and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Download or read book Stroke written by Jens Minnerup and published by Biota Publishing. This book was released on 2013-08-01 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major global health problem because of its large contribution to mortality, morbidity, and disability. The most common form of stroke is ischemic stroke which accounts for approximately 80% of all strokes. During the past decade, our knowledge of the molecular and cellular processes that contribute to stroke pathophysiology has increased substantially and offers many targets for future therapeutic strategies. This book provides an overview of the current knowledge of stroke pathophysiology and the mechanisms that interfere with recovery and regeneration. Moreover, this book reviews the latest advances in the development of future therapeutic strategies.
Download or read book 12 Strokes written by Ferdinand K. Hui and published by Springer Nature. This book was released on 2021-01-11 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, case-based resource provides the state-of-the-art knowledge that can help readers improve access and optimize delivery of stroke thrombectomy. Improving access to stroke is of particular importance because patients often misinterpret their symptoms or cannot speak for themselves if they have aphasia. More importantly, access needs to be organized because stroke therapies are all extremely time-sensitive. Scalable, choreographed protocols are necessary for emergency medical systems to ‘capture’ stroke patients and automatically transport and triage to time-sensitive treatments. Many of the chapters in the first section on Fundamentals and Systems provide valuable insight in improving access to stroke care. Replete with illustrative case studies and emphasizing that treatment approaches to stroke should not be comprised of a one-size-fits-all approach, this illuminating title provides the complete thought, detail, insight and organization that will help readers meet the needs of stroke patients with large vessel occlusions. 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management examines the primary technical principles that underlie the current thrombectomy approaches. Instead of continuing the conceptual dichotomy of stent vs. aspiration, many of the chapters look at underlying principles and then discuss ways in which the currently available devices and approaches can best exploit them. The variety, creativity and detail in many of these chapters will help the reader develop a deeper understanding that might assist their ability to successfully take care of their next patient that ‘doesn’t follow the textbook.’ In addition, the anatomic and pathophysiologic classification of the core Twelve Chapters will help readers organize their thinking and approach. This knowledge, particularly because it is organized based on common, challenging syndromes, will arm the reader to quickly recognize patterns and deftly adapt their management approaches to the needs of the patient. An invaluable contribution to the clinical literature, 12 Strokes: A Case-based Guide to Acute Ischemic Stroke Management will be of great interest to not only neurosurgeons and neurologists but other specialists, primary care providers, and trainees as well.
Book Synopsis Acute Stroke Management in the Era of Thrombectomy by : Edgar A. Samaniego
Download or read book Acute Stroke Management in the Era of Thrombectomy written by Edgar A. Samaniego and published by Springer. This book was released on 2019-06-22 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains a compilation of the revolution of mechanical thrombectomy (MT) in the treatment of strokes. The initial chapters summarize information about the best medical management of acute ischemic stroke, imaging modalities and patient selection for MT. The book then focuses on the nuances of MT, providing detailed information about the best approaches for anesthesia during MT, access, intra-arterial thrombolysis, recent devices and catheters and technical pitfalls of MT. A specific chapter is dedicated to MT in the venous system. This is followed by a chapter about the most common complications of MT and post-procedural care of these patients. The last chapter covers different aspects of acute stroke care and MT in the developing world. The authors of this book comprise of a multidisciplinary group of world experts in the field and were encouraged to include teaching cases to deliver a book with a practical approach. Acute Stroke Management in the Era of Thrombectomy is intended for all healthcare providers who care for patients with stroke; with special emphasis for the proceduralists who are interested in technical tips to improve outcomes and minimize complications.
Download or read book Stroke written by A David Mendelow and published by Elsevier Health Sciences. This book was released on 2015-08-24 with total page 1481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offered in print, online, and downloadable formats, this updated edition of Stroke: Pathophysiology, Diagnosis, and Management delivers convenient access to the latest research findings and management approaches for cerebrovascular disease. Picking up from where J. P. Mohr and colleagues left off, a new team of editors - Drs. Grotta, Albers, Broderick, Kasner, Lo, Mendelow, Sacco, and Wong - head the sixth edition of this classic text, which is authored by the world's foremost stroke experts. Comprehensive, expert clinical guidance enables you to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. Abundant full-color CT images and pathology slides help you make efficient and accurate diagnoses. Data from late-breaking endovascular trials equips you with recent findings. Includes comprehensive coverage of advances in molecular biology of cell death; risk factors and prevention; advances in diagnostics and stroke imaging; and therapeutic options, including a thorough review of thrombolytic agents and emerging data for endovascular therapy. Features brand-new chapters on Intracellular Signaling: Mediators and Protective Responses; The Neurovascular Unit and Responses to Ischemia; Mechanisms of Cerebral Hemorrhage; Stroke Related to Surgery and Other Procedures; Cryptogenic Stroke; and Interventions to Improve Recovery after Stroke. Highlights new information on genetic risk factors; primary prevention of stroke; infectious diseases and stroke; recovery interventions such as robotics, brain stimulation, and telerehabilitation; and trial design. Details advances in diagnostic tests, such as ultrasound, computed tomography (including CT angiography and CT perfusion), MRI (including MR perfusion techniques), and angiography. Includes extracted and highlighted evidence levels. Expert Consult eBook version included with print purchase. This enhanced eBook experience allows you to search all of the text, figures, and references on a variety of devices. The content can also be downloaded to tablets and smart phones for offline use. Combat stroke with the most comprehensive and updated multimedia resource on the pathophysiology, diagnosis, and management of stroke from leaders in the field
Book Synopsis Telestroke: the Use of Telemedicine in Stroke Care by : Thierry Moulin
Download or read book Telestroke: the Use of Telemedicine in Stroke Care written by Thierry Moulin and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue is a dedicated supplement published in addition to the regular issues of 'Cerebrovascular Diseases' focussing on one specific topic. 'Cerebrovascular Diseases' is a well-respected, international peer-reviewed journal in Neurology. Supplement issues are included in the subscription.
Download or read book Stroke E-Book written by James C. Grotta and published by Elsevier Health Sciences. This book was released on 2021-02-06 with total page 1552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by the world's foremost stroke experts, this classic text brings you fully up to date with current research findings and management approaches for cerebrovascular disease. Stroke: Pathophysiology, Diagnosis, and Management, 7th Edition, covers every aspect of this fast-moving field, and is an ideal resource for stroke specialists, general neurologists, and other medical professionals with an interest in stroke. You'll find expert clinical guidance, comprehensive pathophysiology coverage, data from recent trials, advances in diagnostic tests, full-color CT images, pathology slides, and much more, for a complete picture of today's stroke medicine. - Helps you recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan. - Keeps you abreast of the overwhelming volume of studies and guidelines in this dynamic field, providing clear summaries and practical evaluations of all relevant data. - Contains updates throughout, including the latest clinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies, and the new guidelines from the ASA. - Includes new slides for lectures, covering basic science, case studies, and interventional treatment overviews. - Features a Key Points summary at the beginning of each chapter so you can quickly find important information. - Provides abundant full-color CT images and pathology slides that help you make efficient and accurate diagnoses.
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