Neuropeptide Analogs, Conjugates, and Fragments

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Publisher : Academic Press
ISBN 13 : 1483217531
Total Pages : 415 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neuropeptide Analogs, Conjugates, and Fragments by : P. Michael Conn

Download or read book Neuropeptide Analogs, Conjugates, and Fragments written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 13: Neuropeptide Analogs, Conjugates, and Fragments covers the synthesis and characterization of peptide analogs, conjugates, and fragments, their use as ligands for receptors, and their role in the development and use of antisera. The book discusses techniques such as novel synthetic approaches; biotinylation; purification and characterization; radioligand techniques and assay development; use of agonists and antagonists; distinguishing receptor subtypes; conjugation to carrier proteins; antiidiotypic antibody development; and radiolabeling. Neuroscientists, biochemists, neurochemists, and pharmacologists will find the book useful.

Peptidases and Neuropeptide Processing

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Publisher : Academic Press
ISBN 13 : 9780080536422
Total Pages : 407 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis Peptidases and Neuropeptide Processing by :

Download or read book Peptidases and Neuropeptide Processing written by and published by Academic Press. This book was released on 1995-02-08 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Comprehensive protocols included for: Enzymes involved in the activation of bioactive peptidases and proteins Prohormone/neuropeptide processing pathways Enzymes involved in peptide metabolism Posttranslational processing enzymes

Pulsatility in Neuroendocrine Systems

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Publisher : Academic Press
ISBN 13 : 148328834X
Total Pages : 529 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Pulsatility in Neuroendocrine Systems by : Jon E. Levine

Download or read book Pulsatility in Neuroendocrine Systems written by Jon E. Levine and published by Academic Press. This book was released on 2013-10-22 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail. In vitro methods for studying neuroendocrine pulsatility In vivo sampling and recording procedures for monitoring pulsatility in several species Improved quantitative and analytical methods for the study of hormone pulsatility

Neuroimmunology

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Publisher : Academic Press
ISBN 13 : 9780080536439
Total Pages : 434 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis Neuroimmunology by :

Download or read book Neuroimmunology written by and published by Academic Press. This book was released on 1995-03-01 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Comprehensive protocols included for the study of: The brain-immune system The neuroimmune system: Effects of the brain on the peripheral immune system Neuroimmune effects from substances of abuse (e.g. cocaine) to hypnosis Measurement of interferons, cytokines, natural killer cells, and major histocompatibility complex molecules Immunohistochemistry methods in the brain Neuropeptides as immunomodulators

Quantitative Neuroendocrinology

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Author :
Publisher : Elsevier
ISBN 13 : 0080536476
Total Pages : 449 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Quantitative Neuroendocrinology by :

Download or read book Quantitative Neuroendocrinology written by and published by Elsevier. This book was released on 1995-10-16 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume contemporary methods designed to provide insights into, mathematical structure for, and predictive inferences about neuroendocrine control mechanisms are presented. Collates an array of contemporary techniques for analysis of neuroendocrine data Discusses current problems in and solutions to neurohormone pulse analysis Identifies relevant software available

Neurobiology of Cytokines, Part B

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Publisher : Academic Press
ISBN 13 : 1483288315
Total Pages : 310 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neurobiology of Cytokines, Part B by : Errol B. DeSouza

Download or read book Neurobiology of Cytokines, Part B written by Errol B. DeSouza and published by Academic Press. This book was released on 2013-10-22 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system. Methods presented for easy adaptation to new systems Comprehensive protocols included for: The synthesis and release of cytokines; The study of their central nervous system actions; Studying the role of cytokines in human neuropathological conditions

Neurobiology of Cytokines

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Publisher : Academic Press
ISBN 13 : 1483217558
Total Pages : 369 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neurobiology of Cytokines by : Errol B. De Souza

Download or read book Neurobiology of Cytokines written by Errol B. De Souza and published by Academic Press. This book was released on 2013-10-22 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Cytokines, Part A provides an overview of the effects of cytokines in the brain and in the endocrine system. The book discusses the general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the blood-brain barrier. The text also describes the anatomical localization of cytokines, cytokine receptors, and their respective mRNA in brain and in endocrine tissues. The methods for evaluating the in vivo as well as in vitro actions of cytokines on hormone secretion are also considered. The book further tackles the synthesis and release of cytokines and their central nervous system actions; and the methodology for studying the role of cytokines in human neuropathological conditions.

Paradigms for the Study of Behavior

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Publisher : Academic Press
ISBN 13 : 148326937X
Total Pages : 497 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Paradigms for the Study of Behavior by : P. Michael Conn

Download or read book Paradigms for the Study of Behavior written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 14: Paradigms for the Study of Behavior is a collection of articles that describes the methods for measuring a wide range of behavior. This volume covers the means for measuring different behaviors, such as reproductive, maternal, sexual, aggression, social interactions, feeding behavior, memory analysis, and classical conditioning. The opening papers outline the proper conditions and practical considerations in which the researcher can study the sexual and reproductive behavior of animals in the laboratory. Another paper describes how to assess aggressiveness in rodents including ethical issues involved in such study. The book then discusses the effects of intracerebral administration of neuropeptides in rats using surgical and stereotaxic methods. Another paper presents the measurement of behavioral thermoregulatory reflexes to show acuity of temperature sensation and thermoregulatory control. This volume also discusses the measurement of song-learning behavior in birds through ""sensorimotor,"" ""action-based,"" and ""sensory"" methods of learning. This book will be helpful for students, scientists, technicians, and laboratory workers whose work involves experiments that need to be accurately measured.

G Proteins

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Publisher : Elsevier
ISBN 13 : 9780080532271
Total Pages : 410 pages
Book Rating : 4.5/5 (322 download)

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Book Synopsis G Proteins by : Patrick C. Roche

Download or read book G Proteins written by Patrick C. Roche and published by Elsevier. This book was released on 1996-03-27 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: G Proteins

Neurobiology of Steroids

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Publisher : Academic Press
ISBN 13 : 1483288366
Total Pages : 573 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Neurobiology of Steroids by : E. Ronald de Kloet

Download or read book Neurobiology of Steroids written by E. Ronald de Kloet and published by Academic Press. This book was released on 2013-10-22 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions. Comprehensive protocols included for the study of Steroid kinetics and metabolism Steroid receptors Molecular and cellular effects of steroids Steroid effects on integrated systems

Nitric Oxide Synthase: Characterization and Functional Analysis

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Author :
Publisher : Academic Press
ISBN 13 : 0080536379
Total Pages : 375 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Nitric Oxide Synthase: Characterization and Functional Analysis by :

Download or read book Nitric Oxide Synthase: Characterization and Functional Analysis written by and published by Academic Press. This book was released on 1996-09-18 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the function of nitric oxide in a regulatory capacity in the central and peripheral nervous system is widely recognized, the full scope of its actions and its interrelationships with other classes of regulatory molecules is just beginning to be comprehended. This volume contains a number of sophisticated and advanced methods essential for exploring the activity of nitric oxide in the brain. It will be a valuable tool for the established investigator and for those just entering the field. Comprehensive protocols included for detection of NO and related compounds by chemical, immunohistochemical, and in situ hybridization techniques Newly developed methods for the purification of neuronal and endothelial NO synthase, production of monoclonal antibodies to NO synthase, molecular cloning and expression of NO synthesis, and control of NO synthase gene expression Assessment of NO-mediated functions in neurons, central nervous system, cerebral circulation, synaptic transmission, and vascular tone Calcium imaging by confocal microscopy, evaluation of the effect of NO on iron metabolism, and detection of heme oxygenase-1 and -2 message level and distribution

Photoreceptor Cells

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Publisher : Academic Press
ISBN 13 : 148321754X
Total Pages : 425 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Photoreceptor Cells by : Paul A. Hargrave

Download or read book Photoreceptor Cells written by Paul A. Hargrave and published by Academic Press. This book was released on 2013-10-22 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photoreceptor Cells, Volume 15 covers the advances in the study of photoreceptor cells. The book discusses biochemical, cell and structural biological, and molecular biological techniques needed for the study of photoreceptor cells. The text also describes the methods for observing the structure of photoreceptor cells and for studying their metabolism. The procedures for photoreceptor cell isolation are also considered. The book further tackles the preparation of proteins involved in rod cell metabolism, with particular emphasis on proteins of the visual transduction cascade. The text also encompasses the application of molecular biological techniques for the examination of molecular components of the visual system and their structure, distribution, and function. Neuroscientists, ophthalmologists, biochemists, and people involved in the study of photoreceptor cells will find the book invaluable.

Receptor Molecular Biology

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Author :
Publisher : Elsevier
ISBN 13 : 9780080536446
Total Pages : 519 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis Receptor Molecular Biology by :

Download or read book Receptor Molecular Biology written by and published by Elsevier. This book was released on 1995-03-22 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Cloning Expression systems Signal transduction Structure-function techniques Antireceptor antibodies Regulation 3-D receptor modeling and computational probing

Paradigms of Neural Injury

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Publisher : Academic Press
ISBN 13 : 0080536484
Total Pages : 355 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Paradigms of Neural Injury by :

Download or read book Paradigms of Neural Injury written by and published by Academic Press. This book was released on 1996-05-23 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes paradigms, model systems, and techniques for the study of dysfunctions in the nervous system. The advantages and disadvantages of the approaches presented are critically discussed. Neural injury Developmental cell death Disease processes and aging

PCR in Neuroscience

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Publisher : Elsevier
ISBN 13 : 9780080536453
Total Pages : 455 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis PCR in Neuroscience by :

Download or read book PCR in Neuroscience written by and published by Elsevier. This book was released on 1995-04-13 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Direct application of PCR to fresh or frozen clinical specimens (e.g., blood and solid tissue) Complete retrieval of novel expressed genes by PCR without screening a library Quantitation by PCR Mutagenesis by PCR PCR in AIDS research Simple and effective protocols for PCR on archival specimens

Receptors

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Publisher : Academic Press
ISBN 13 : 1483259706
Total Pages : 457 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Receptors by : P. Michael Conn

Download or read book Receptors written by P. Michael Conn and published by Academic Press. This book was released on 2013-10-22 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

Ion Channels of Excitable Cells

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Publisher : Academic Press
ISBN 13 : 1483288331
Total Pages : 402 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Ion Channels of Excitable Cells by : Toshio Narahashi

Download or read book Ion Channels of Excitable Cells written by Toshio Narahashi and published by Academic Press. This book was released on 2013-10-22 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of the highly significant and widely recognized roles of ion channels in physiology, pathophysiology, pharmacology, and toxicology, the term ion channel has now become a household word in the biomedical sciences. This volume covers preparations and techniques for the study of various ion channels. Both voltage-gated and ligand-gated ion channels of neurons, axons, and cardiac and smooth muscles are covered. It includes not only patch clamp techniques but molecular biology and imaging techniques as well. Comprehensive protocols included for the study of: Ion channels using patch-clamp, molecular biology, and imaging techniques Role of ion channels in physiology, pathophysiology, pharmacology, and toxicology Specific ion channels of specific tissues