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Author : Giovanni Biggio
Publisher : Liviana Scolastica
ISBN 13 :
Total Pages : 172 pages
Book Rating : 4.3/5 (91 download)
Download or read book Neuronal Plasticity and Trophic Factors written by Giovanni Biggio and published by Liviana Scolastica. This book was released on 1988 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author : Sten Linnarsson
Publisher :
ISBN 13 : 9789162846183
Total Pages : 1 pages
Book Rating : 4.8/5 (461 download)
Download or read book Neurotrophic Factors and Neuronal Plasticity written by Sten Linnarsson and published by . This book was released on 2001 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dale Purves
Publisher : Harvard University Press
ISBN 13 : 9780674077164
Total Pages : 244 pages
Book Rating : 4.0/5 (771 download)
Download or read book Body and Brain written by Dale Purves and published by Harvard University Press. This book was released on 1988 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major goal of developmental neurobiology is to understand how the nervous system is put together. A central theme that has emerged from research in this field over the last several decades is the crucial role of trophic interactions in neural assembly, and indeed throughout an animal's life. Trophic--which means nutritive--refers to long-term interdependencies between nerve cells and the cells they innervate. The theory of trophic effects presented in this book offers an explanation of how the vertebrate nervous system is related to--and regulated by--the body it serves. The theory rationalizes the nervous system's accommodation, throughout life, to the changing size and form of the body it tenants, indicating the way connections between nerve cells change in response to stimuli as diverse as growth, injury, experience, and natural selection. Dale Purves, a leading neurobiologist best known for his work on the formation and maintenance of synaptic connections, presents this theory within the historical setting of earlier ideas about neural organization--from Weiss's theory of functional reorganization to the chemoaffinity theory championed by Sperry. In addition to illuminating eighty years of work on trophic interactions, this book asks its own compelling questions: Are trophic interactions characteristic of all animals or only of those with complex nervous systems? Are trophic interactions related to learning? What does the trophic theory of neural connections imply about the currently fashionable view that the nervous system operates according to Darwinian principles? Purves lays the theoretical foundation for practical exploration of trophic interactions as they apply to neural connections, a pursuit that will help us understand how our own nervous systems generate change. The ideas in this book not only enrich neurobiology but also convey the profound relevance of neuroscience to other fields of life science.
Author : George J. Siegel
Publisher : Lippincott Raven
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.3/5 (91 download)
Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.
Author : Sandra E. Loughlin
Publisher : Elsevier
ISBN 13 : 0080571328
Total Pages : 632 pages
Book Rating : 4.0/5 (85 download)
Download or read book Neurotrophic Factors written by Sandra E. Loughlin and published by Elsevier. This book was released on 2012-12-02 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function Includes special chapters on primary, secondary, and tertiary messenger systems Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity
Author : Silvia Alboni
Publisher : Frontiers Media SA
ISBN 13 : 2889197689
Total Pages : 160 pages
Book Rating : 4.8/5 (891 download)
Download or read book Cytokines as Players of Neuronal Plasticity and Sensitivity to Environment in Healthy and Pathological Brain written by Silvia Alboni and published by Frontiers Media SA. This book was released on 2016-03-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now accepted that immune molecules are not only present within the brain during pathology but they exert physiological functions in the “healthy” brain as well. Increasing evidence points to a neuro-modulatory role of cytokines and chemokines (CHEMOtactic cytoKINES) in basal transmission and plasticity processes where signaling between peri-synaptic astrocytes, microglia and neurons plays an important role. Nevertheless, the exact mechanisms as to how cytokines, and in particular chemokines, participate in the molecular and cellular processes thought to subserve memory formation, plasticity processes and responsiveness to environmental stimuli remain to be clarified. Interestingly, in in vitro preparations, molecules like TNF-α, interleukin (IL)-1β, IL-6, CX3CL1, CXCL12, CCL2 and CCL3 are implicated in synaptic formation and scaling, in modulation of glutamatergic transmission, in plasticity and neurogenesis, in particular in the hippocampus. The hippocampus is an extremely plastic structure, one of the main neurogenic niches in the adult brain, that exhibits a marked sensibility to environmental stimuli. Indeed exposure of mice to environmental enrichment (EE) modifies learning and memory abilities increasing neurogenesis and neuronal plasticity whether exposure to severe stressful experiences diminishes neurotrophic support, impairs neurogenesis, plasticity and cognition. In the hippocampus cytokines play a key role in mediating both positive as well as negative effects of the environment affecting neuronal plasticity also in stress related pathologies, such as depression. It has been reported that mice lacking type 1 receptor for IL-1 display impaired hippocampal memory and LTP that are restored by EE; moreover negative effects on neuronal plasticity (and thus behavior) induced by stress exposure can be prevented by blocking IL-1 activity. In addition, mice lacking IL-6 have improved cognitive functions whereas the absence of microglia-driven CX3CR1 signaling increases hippocampal plasticity and spatial memory occluding the potentiating effects of EE. However, the factors mediating the effect of environmental stimuli on behavior and plasticity has been only partially identified. Interestingly, it has been suggested that chemokines can play a key role in the flexibility of hippocampal structure and may modulate neuronal signaling during behavior. The question is how cytokines may translate environmental stimuli in plasticity and behavioral changes. This research topic is proposed to explore the role of cytokines, and more in particular chemokines, in the modulation of neuronal activity as a fundamental step for the correct brain wiring, function and susceptibility to environment. We encourage the submission of original research reports, review articles, commentaries, perspectives or short communications, in the following (but not limited to) topics: - Role of cytokines and chemokines in neuronal plasticity - Immune molecules and responsiveness to environment - Role of chemokine in the flexibility of hippocampal structure
Author : Julian Luke Goggi
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (591 download)
Download or read book Brain-derived Neurotrophic Factor and Neural Plasticity written by Julian Luke Goggi and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Catherine Belzung
Publisher : Springer Science & Business Media
ISBN 13 : 364236232X
Total Pages : 447 pages
Book Rating : 4.6/5 (423 download)
Download or read book Neurogenesis and Neural Plasticity written by Catherine Belzung and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Author : Ales Stuchlik
Publisher : BoD – Books on Demand
ISBN 13 : 1789233569
Total Pages : 180 pages
Book Rating : 4.7/5 (892 download)
Download or read book The Hippocampus written by Ales Stuchlik and published by BoD – Books on Demand. This book was released on 2018-07-11 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.
Author : Bryan Kolb
Publisher : Psychology Press
ISBN 13 : 9780805815207
Total Pages : 226 pages
Book Rating : 4.8/5 (152 download)
Download or read book Brain Plasticity and Behavior written by Bryan Kolb and published by Psychology Press. This book was released on 1995 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.
Author : Carl W. Cotman
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.:/5 (45 download)
Download or read book Neuronal Plasticity written by Carl W. Cotman and published by . This book was released on 1978 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anne M. Fagan
Publisher :
ISBN 13 :
Total Pages : 668 pages
Book Rating : 4.:/5 (318 download)
Download or read book Mechanisms of Injury-induced Neuronal Plasticity in the Adult Mammalian CNS: Investigation of Cellular Interactions and Trophic Factor Expression in the Denervated Rat Hippocampus written by Anne M. Fagan and published by . This book was released on 1992 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Donald G. Stein
Publisher : Oxford University Press, USA
ISBN 13 : 9780195119183
Total Pages : 190 pages
Book Rating : 4.1/5 (191 download)
Download or read book Brain Repair written by Donald G. Stein and published by Oxford University Press, USA. This book was released on 1997 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over a half million people each year suffer brain-damaging injuries and diseases--but the outlook for their eventual recovery is far more hopeful than it was just a short while ago. In Brain Repair, three internationally renowned neuroscientists team up to offer an intriguing and up-to-the-minute introduction to the explosive advances being made in the research, technology, and treatment of brain damage. The key to neuroscience's most exciting discoveries to date is a theory that is rapidly gaining adherents in the scientific community--the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. In clear, accessible language, the authors show us that the brain manufactures a host of complex chemicals that actually foster growth in damaged brain cells. We visit the laboratories where researchers are untangling the mystery of Parkinson's disease and trying to understand what goes wrong in stroke victims, and why some, thought permanently impaired, show remarkable improvements. In addition, they discuss how even today misguided ideas can adversely affect how physicians treat patients. And, along the way, they detail the fascinating history of how brain structure and functioning has been understood and studied, from prehistoric times to the present. A best-selling volume in France and Mexico, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.
Author : Carlos B. Duarte
Publisher : Humana
ISBN 13 : 9781493989690
Total Pages : 258 pages
Book Rating : 4.9/5 (896 download)
Download or read book Brain-Derived Neurotrophic Factor (BDNF) written by Carlos B. Duarte and published by Humana. This book was released on 2019-07-10 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses the latest techniques and methodologies used in the neurotrophin field to study the physiology of the Brain-Derived Neurotrophic Factor (BDNF). The book provides the tools essential to any researcher that intends to explore the peculiar regulation of this neurotrophin from gene expression to its release and the signaling by TrkB receptors, as well as to study the neuronal responses to BDNF or the role of neurotrophin in various neurological diseases. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting edge and comprehensive, Brain-Derived Neurotrophic Factor(BDNF) is a valuable resource for researchers who want to further study the diversity of physiological roles of this important growth factor.
Author : Richard L. Masland
Publisher : Liviana Scolastica
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)
Download or read book Neuroplasticity written by Richard L. Masland and published by Liviana Scolastica. This book was released on 1987 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yuri Bozzi
Publisher : Edizioni della Normale
ISBN 13 : 9788876422720
Total Pages : 147 pages
Book Rating : 4.4/5 (227 download)
Download or read book A study on the activity-dependent expression of neurotrophic factors in the rat visual system written by Yuri Bozzi and published by Edizioni della Normale. This book was released on 1997-10-01 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensory experience can dynamically modify both the anatomy and function of the brain. In particular, neurons can modify their connections in response to enviromental stimuli. This process, generally referred to as “neuronal plasticity”, is the basis of learning and memory processes in the brain. Which are the bases of neuronal plasticity? That is, how can environmental factors and sensory experience modify the connections between neurons? Neurotrophic factors of the Nerve Growth Factor (NGF) family are known to finely regulate the development and maintenance of synaptic connections in the PNS. The results obtained by the group of Maffei firstly suggested the hypothesis that neurotrophic factors could play a key role in the plasticity of the mammalian visual system. The purpose of this thesis is to give a general overview about the recent advances in the field of neurotrophine-regulated plasticity of the mammalian visual system.
