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Author : Bert Merton Zuckerman
Publisher :
ISBN 13 : 9780127824017
Total Pages : pages
Book Rating : 4.8/5 (24 download)
Download or read book Nematodes as Biological Models: Aging and other model systems written by Bert Merton Zuckerman and published by . This book was released on 1980 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bert M. Zuckerman
Publisher : Elsevier
ISBN 13 : 1483259641
Total Pages : 321 pages
Book Rating : 4.4/5 (832 download)
Download or read book Aging and Other Model Systems written by Bert M. Zuckerman and published by Elsevier. This book was released on 2013-10-22 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nematodes as Biological Models, Volume 2: Aging and Other Model Systems contains discussions on free-living nematodes as biological models for pharmacologic and toxicant testing, and for studies on gerontology and nutrition. The book presents specific chapters that cover topics on nematodes as models to study aging; nematodes as nutritional models; physiology and morphology of nematodes; and models and mechanisms on longevity and survival in nematodes. Geneticists, cell and developmental biologists, neurologists, endocrinologists, toxicologists, nutritionists, and gerontologists will find the book invaluable.
Author : David B. Dusenbery
Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.:/5 (318 download)
Download or read book Nematodes as Biological Models: Behavioral and developmental models written by David B. Dusenbery and published by . This book was released on 1980 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: V. 1. Behavioral and developmental models.--v. 2. Aging and other model systems.
Author : Bert Merton Zuckerman
Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.:/5 (319 download)
Download or read book Nematodes as Biological Models: Aging and other model systems written by Bert Merton Zuckerman and published by . This book was released on 1980 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Itamar Glazer
Publisher : CABI
ISBN 13 : 1789248795
Total Pages : 386 pages
Book Rating : 4.7/5 (892 download)
Download or read book Nematodes as Model Organisms written by Itamar Glazer and published by CABI. This book was released on 2022-05-16 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nematodes are small multicellular organisms that have been used as biological models since the 1960s. For example, Caenorhabditis elegans is a free-living nematode worm, about 1mm in length, that lives in temperate soil environments. It is made up of about 1000 cells, and has a short life cycle of only two weeks. It was the first multicellular organism to have its whole genome sequenced. The book summarizes the importance of nematodes as model organisms in the fields of genetics, developmental biology, neurobiology, pharmacology, nutrition, ecology and parasitology. Of interest to a broad audience across a wide spectrum of disciplines, this book is useful for biologists working on comparative studies to investigate biological processes across organisms; medical scientists and pharmacologists for exploration of drugs and medicine (including the use of genome editing to eliminate diseases); ecologists considering nematodes as indicators for environment changes; and parasitologists for host-parasite interactions. Many other researchers can use this book as a benchmark for the broad implications of nematology research on other aspects of science.
Author : Heinz Osiewacz
Publisher : Taylor & Francis US
ISBN 13 : 9781402014062
Total Pages : 296 pages
Book Rating : 4.0/5 (14 download)
Download or read book Aging of Organisms written by Heinz Osiewacz and published by Taylor & Francis US. This book was released on 2003-10-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Volume of the Series is devoted to aging at the organismic level. Different levels of organisation, ranging from single cell organisms (yeast) to humans are included. In addition to the currently most important model systems like yeast, filamentous fungi, Caenorabditis elegans, flies and mice, other systems like sponges and plants are discussed. Most importantly, research using different aging models can be expected to unravel the most important basic mechanisms of aging that are conserved in all species. In addition, a critical discussion of what can be expected from this kind of strategy for the understanding of aging in humans is included. This book serves as excellent reading for graduate students, scientists in Medical Research, Medical doctors, researchers in pharmacological fields, researchers, biologists, and experts of this area.
Author :
Publisher : Academic Press
ISBN 13 : 0128161787
Total Pages : 452 pages
Book Rating : 4.1/5 (281 download)
Download or read book Nematode Models of Development and Disease written by and published by Academic Press. This book was released on 2021-05-13 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nematode Models of Development and Disease, Volume 144 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters surrounding Transgenerational inheritance, Oscillatory expression and function, Concepts and functions of small RNA pathways in C. elegans, Exploring the nuclear lamina in health and pathology using C. elegans, Cellular Plasticity, Morphogenesis, Tubulogenesis, Organogenesis forces, Programmed cell fusion in development and homeostasis, One template, two outcomes: how does the sex-shared nervous system generate sex-specific behaviors?, Metabolic Cellular Coordination of Gene-Environment Interactions, and much more. Other chapters cover Chemical and physical cues and micro-evolution in early embryogenesis, Innate immunity, Sex and Death, Dendrites maturation, axonal growth and extracellular glycoproteins, Autophagocytosis, Spermatogenesis, and the developmental and physiological roles of phagocytosis in Caenorhabditis elegans. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Author : Jyotiska Chaudhuri
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (868 download)
Download or read book Nematodes with Three Genders written by Jyotiska Chaudhuri and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: All living organisms reproduce and age. These are the two basic facets of life, but in many aspects poorly understood. The majority of the species are male/female. The proportion of genders in population can vary significantly among animals and plants, but the mechanisms and evolutionary reasons for such variation are poorly understood. In some species of nematode (roundworm) parasites, for example, only female progeny is generated after a cross between a male and female. To understand how gender-ratio distortion happens and how it evolved, we are using a non-parasitic nematode that can be cultured in the laboratory, but that is similar in many aspects to parasitic nematode. For my thesis, I studied the evolution, maintenance and the underlying cellular mechanisms that govern extreme skewed sex ratios in free-living and parasitic nematode species. This knowledge could be used to screen for drugs that further suppress the production of males in the future, helping to eradicate important parasites that cause debilitating diseases worldwide in livestock and humans. Aging rates can vary dramatically in various species, but it is not understood why and how this happens. I found that our model nematode produce two genders that age at significantly different rates and that respond differently to cellular stress, although they are genetically identical. Here, I clarified the mechanism behind this gender difference in lifespan. This could help design potential targets for drugs to address age-related diseases to improve our health-span in future.
Author : William Barry Wood
Publisher :
ISBN 13 :
Total Pages : 694 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Nematode Caenorhabditis Elegans written by William Barry Wood and published by . This book was released on 1988 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rachel A. Ankeny
Publisher : Cambridge University Press
ISBN 13 : 110866556X
Total Pages : 156 pages
Book Rating : 4.1/5 (86 download)
Download or read book Model Organisms written by Rachel A. Ankeny and published by Cambridge University Press. This book was released on 2021-01-28 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Element presents a philosophical exploration of the concept of the 'model organism' in contemporary biology. Thinking about model organisms enables us to examine how living organisms have been brought into the laboratory and used to gain a better understanding of biology, and to explore the research practices, commitments, and norms underlying this understanding. We contend that model organisms are key components of a distinctive way of doing research. We focus on what makes model organisms an important type of model, and how the use of these models has shaped biological knowledge, including how model organisms represent, how they are used as tools for intervention, and how the representational commitments linked to their use as models affect the research practices associated with them. This title is available as Open Access on Cambridge Core.
Author : Donald L Lee
Publisher : CRC Press
ISBN 13 : 0415272114
Total Pages : 651 pages
Book Rating : 4.4/5 (152 download)
Download or read book The Biology of Nematodes written by Donald L Lee and published by CRC Press. This book was released on 2002-01-10 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biology of Nematodes synthesizes knowledge of the biology of free-living, plant-parasitic, and animal-parasitic nematodes. Contributed works by recognized researchers apply groundbreaking molecular techniques, many of which resulted from work on Caenorhabditis elegans, toward new approaches to the study of nematode worms. Topics covered include: ̈ Systematics and phylogeny ̈ Neuromuscular physiology ̈ Locomotion ̈ Sense organs ̈ Behavior ̈ Aging ̈ The nematode genome ̈ Survival strategies ̈ Immunology ̈ Epidemiology ̈ Structure and organization ̈ Gametes and fertilization ̈ Development ̈ Feeding, digestion, and metabolism
Author : Donald L. Riddle
Publisher : Firefly Books
ISBN 13 : 9780879695323
Total Pages : 1252 pages
Book Rating : 4.6/5 (953 download)
Download or read book C. Elegans II written by Donald L. Riddle and published by Firefly Books. This book was released on 1997 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defines the current status of research in the genetics, anatomy, and development of the nematode C. elegans, providing a detailed molecular explanation of how development is regulated and how the nervous system specifies varied aspects of behavior. Contains sections on the genome, development, neural networks and behavior, and life history and evolution. Appendices offer genetic nomenclature, a list of laboratory strain and allele designations, skeleton genetic maps, a list of characterized genes, a table of neurotransmitter assignments for specific neurons, and information on codon usage. Includes bandw photos. For researchers in worm studies, as well as the wider community of researchers in cell and molecular biology. Annotation copyrighted by Book News, Inc., Portland, OR
Author : Thomas Nyström
Publisher : Springer Science & Business Media
ISBN 13 : 9783540024903
Total Pages : 328 pages
Book Rating : 4.0/5 (249 download)
Download or read book Model Systems in Aging written by Thomas Nyström and published by Springer Science & Business Media. This book was released on 2004 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process. This book takes the reader from unicellular bacterial deterioration via senescence in fungi and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories.
Author : Caleb E. Finch
Publisher : University of Chicago Press
ISBN 13 : 9780226248899
Total Pages : 948 pages
Book Rating : 4.2/5 (488 download)
Download or read book Longevity, Senescence, and the Genome written by Caleb E. Finch and published by University of Chicago Press. This book was released on 1994-05-16 with total page 948 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Author : David B. Dusenbery
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.:/5 (319 download)
Download or read book Nematodes as Biological Models: Behavioral and developmental models written by David B. Dusenbery and published by . This book was released on 1980 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: V. 1. Behavioral and developmental models.--v. 2. Aging and other model systems.
Author : Sean R. Gallagher
Publisher : John Wiley & Sons
ISBN 13 : 047094241X
Total Pages : 679 pages
Book Rating : 4.4/5 (79 download)
Download or read book Current Protocols Essential Laboratory Techniques written by Sean R. Gallagher and published by John Wiley & Sons. This book was released on 2012-03-19 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.
