Natural Cell-Mediated Immunity Against Tumors

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Author :
Publisher : Elsevier
ISBN 13 : 0323141730
Total Pages : 1345 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Natural Cell-Mediated Immunity Against Tumors by : Ronald Herberman

Download or read book Natural Cell-Mediated Immunity Against Tumors written by Ronald Herberman and published by Elsevier. This book was released on 2012-12-02 with total page 1345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly a collection of different research contributed by leading laboratories. It also presents a better perspective of how natural mechanisms fit in with and relate to the traditional and more extensively studied components of the immune system. The book starts off with an overview of the contents of the volume – the historical development of the advances in the field of research and the status of knowledge in the subject area. Divided into four major sections, the book consists of a total of 98 chapters. The sections discuss the natural killer cells and related cells and the natural lymphokine production. This book also explains the natural macrophage and granulocyte cytotoxicity. The book will be a helpful reference for students, professionals, and researchers in biology, immunology, biochemistry, microbiology, and other related fields.

NK Cells and Other Natural Effector Cells

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Publisher : Elsevier
ISBN 13 : 032313971X
Total Pages : 1607 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis NK Cells and Other Natural Effector Cells by : Ronald B. Herberman

Download or read book NK Cells and Other Natural Effector Cells written by Ronald B. Herberman and published by Elsevier. This book was released on 2012-12-02 with total page 1607 pages. Available in PDF, EPUB and Kindle. Book excerpt: NK Cells and Other Natural Effector Cells reviews the state of knowledge on NK cells and other natural effector mechanisms. The coverage of immune effector systems ranges from basic studies on their nature, regulation, and mechanisms of action to important practical issues such as their role in host resistance, their modulation by therapeutic intervention, and alterations of their activity in disease. The book is organized into 12 parts. Parts I and II examine the characteristics of NK cells and other natural effector cells, respectively. Part III focuses on the cell lineage of NK and related effector cells, providing evidence for or against T cell lineage, for or against macrophage lineage, and for or against other or separate lineage. Part IV deals with the genetics of natural resistance in the mouse and rat. Part V presents studies on the regulation of cytotoxic activity. Part VI examines the specificity of natural effector cells, covering the nature of target cell structures and the nature of recognition receptors in effector cells. Part VII discusses the cytotoxicity by cultured lymphoid cells while Part VIII turns to the mechanisms of cytotoxicity. Part IX deals with natural cell-mediated reactivity against primary tumor cells and against non-tumor targets. Part X examines NK cell tumors or the presence of NK cells at the site of tumor growth. Part XI presents clinical studies with natural effector cells. Part XII provides evidence for in vivo reactivity of natural effector cells.

Natural Killer Cells

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Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Natural Killer Cells by : Bernard Serrou

Download or read book Natural Killer Cells written by Bernard Serrou and published by . This book was released on 1982 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ICRDB Cancergram

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.:/5 (3 download)

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Book Synopsis ICRDB Cancergram by :

Download or read book ICRDB Cancergram written by and published by . This book was released on 1985 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural and Induced Cell-Mediated Cytotoxicity

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Publisher : Academic Press
ISBN 13 : 1483269825
Total Pages : 257 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Natural and Induced Cell-Mediated Cytotoxicity by : Gert Riethmüller

Download or read book Natural and Induced Cell-Mediated Cytotoxicity written by Gert Riethmüller and published by Academic Press. This book was released on 2014-06-28 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural and Induced Cell-Mediated Cytotoxicity: Effector and Regulatory Mechanisms contains the proceedings of the Erwin Riesch Symposium organized on the occasion of the Fifth Centennial of the University of Tübingen in Germany on October 20-23, 1977. The symposium provided a forum for reviewing the progress that has been made in understanding the effector and regulatory mechanisms underlying natural and induced cell-mediated cytotoxicity. Topics covered range from the immunobiology of natural killer cells to the role of macrophages as regulator, accessory, and effector cells in cytotoxicity. Comprised of 27 chapters, this book begins by analyzing the characteristics of natural cytotoxic cells in mice, followed by a discussion on the generation in vivo of mouse natural cytotoxic cells and the role of cytotoxic T cells in the local defense against solid tumors. Subsequent chapters focus on the natural cytotoxicity of human lymphocytes; opposing effects of interferon on natural killer and target cells; susceptibility of cloned melanoma to natural cytotoxicity; and cell-mediated immunity against avian virus-induced tumor cells. The book also examines alternative routes of entry for cell surface antigens into the immune system before concluding with a chapter that considers interferon induction by Corynebacterium parvum. This monograph should be of value to students, researchers, and practitioners in the fields of biology and immunology.

Mechanisms of Cell-Mediated Cytotoxicity

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468489593
Total Pages : 577 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Mechanisms of Cell-Mediated Cytotoxicity by : William R. Clark

Download or read book Mechanisms of Cell-Mediated Cytotoxicity written by William R. Clark and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First International Workshop on Mechanisms in Cell-Mediated Cytoxicity was held at Carry-Ie-Rouet, France, September 14-16, 1981. The Workshop brought together for the first time leading investiga tors in each of the principal areas of cell-mediated cytotoxicity, as well as experts in the area of complement-mediated cytoxicity. Formal research presentations were held to a minimum, the emphasis being on open discussion of current knowledge about mechanisms of cytoxicity in each of the systems under consideration. The major objectives of the Workshop were 1) to compare and integrate what is known about the mechanism(s) of cytoxicity in each system; 2) to determine whether, on the basis of information in hand, it seems likely that the mechanisms of cytotoxicity in the various systems are the same or are unique; and 3) to stimulate thinking about new approaches to elucidating the fundamental mechanisms by which certain cells are able to kill other cells.

Cancer Immunology: Innovative Approaches to Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9780898387575
Total Pages : 250 pages
Book Rating : 4.3/5 (875 download)

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Book Synopsis Cancer Immunology: Innovative Approaches to Therapy by : Ronald B. Herberman

Download or read book Cancer Immunology: Innovative Approaches to Therapy written by Ronald B. Herberman and published by Springer Science & Business Media. This book was released on 1986-02-28 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the second in the 'Cancer Treatment and Research' series focussing on basic and clinical tumor immunology. It has a rather different focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up dated summaries in various areas of classical tumor immunology: specific antitumor immunity, the immunologic competence of cancer patietns, char acterization of human tumor-associated antigens, the ability to propagate specifically immune T cells in culture in the presence of interleukin 2, and the use of such cells for adoptive immunotherapy of established tumors. of evidence concerning the immune However, it also reviewed the status surveillance hypothesis and pointed out the need to consider non-T cell mediated mechanisms of host resistance. In particular, one chapter sum marized information on the role of macrophages in host resistance against tumors. The present volume continues to emphasize one of the major themes of the first volume, innovative approaches to the therapy of cancer. It involves contributions from leading investigators on several primary types of therapeutic interventions related to monoclonal antibodies, the col laboration of monoclonal antibodies with macro phages to mediate antibody dependent cellular cytotoxicity, lymphokines, tumor vaccines, and natural killer cells. It also has an up-to-date summary of the immunologic aspects of the exciting and promising work being performed on human T cell leukemia virus in the laboratory of Dr. Robert Gallo.

Functions of the Natural Immune System

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Publisher : Springer Science & Business Media
ISBN 13 : 1461307155
Total Pages : 486 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Functions of the Natural Immune System by : C.W. Reynolds

Download or read book Functions of the Natural Immune System written by C.W. Reynolds and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty contributions examine a variety of functions reportedly mediated by cells within the natural immune system and review the diverse functional activities of the lymphoid cells. Major emphasis is on the reactivity of natural effector cells specifically within the lymphoid populations. Annotation

Tumor Immunology and Cancer Therapy

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Publisher : CRC Press
ISBN 13 : 1000148300
Total Pages : 346 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Tumor Immunology and Cancer Therapy by : R. H. Goldfarb

Download or read book Tumor Immunology and Cancer Therapy written by R. H. Goldfarb and published by CRC Press. This book was released on 2020-07-24 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a Tumor Immunology Symposium held in Pittsburgh, this work provides comprehensive coverage of the most important aspects of tumor immunology. It reveals novel approaches to the immunotherapy of cancer and presents complex issues in an accessible manner.

Mechanisms of Cell-Mediated Cytotoxicity II

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Publisher : Springer Science & Business Media
ISBN 13 : 1468483269
Total Pages : 560 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Mechanisms of Cell-Mediated Cytotoxicity II by : Pierre Henkart

Download or read book Mechanisms of Cell-Mediated Cytotoxicity II written by Pierre Henkart and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is derived from contributions to the Second International Workshop on Mechanisms in Cell-Mediated Cytotoxicity, held in Annopolis, Maryland, June 10-13, 1984. This workshop was organized by an international committee of immunologists interested in lymphocyte cytotoxic mechanisms (G. Berke, W.R. Clark, P. Golstein, M. Hanna, P. Henkart, R. Herberman, H.R. MacDonald, E. Martz, and C. Nathan), who strove to invite participants who have made major contributions to this field. The Workshop was a follow-up to the highly successful 1981 Workshop, whose proceedings Workshop were published by Plenum as Mechanisms in Cell-Mediated Cytotoxicity, edited by W.R. Clark and P. Golstein. That volume has been much appreciated by researchers and students since it contains accounts of most of the current approaches to understanding cytotoxic lymphocyte mechanisms all in one volume. The present book may be viewed as a follow-up to the first one, and in our opinion fairly summarizes the varying current viewpoints on lymphocyte cytotoxic mechanism. It should be noted that the discussions have been transcribed directly by us, and the participants have not had an opportunity to edit their remarks. We have tried to maintain some of the style of the actual discussion in these transcripts. In some cases technical problems prevented usable transcriptions from being made, and hence not all of the actual discussion at the workshop is reproduced here.

Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889638766
Total Pages : 146 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer by : Loredana Cifaldi

Download or read book Molecular Strategies Aimed to Boost NK Cell-based Immunotherapy of Cancer written by Loredana Cifaldi and published by Frontiers Media SA. This book was released on 2020-07-31 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Research Topic, we would like to honor the memory of Prof. Vito Pistoia and pay tribute to his scientific contributions to the field of Cancer Immunity and Immunotherapy. Topic Editor Daniel Olive is the co-founder and shareholder of company Imcheck Therapeutics. All other topic editors declare no competing interests with regards to the Research Topic subject.

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Nk Cell Mediated Cytotoxicity

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Publisher : CRC Press
ISBN 13 : 9780849362675
Total Pages : 524 pages
Book Rating : 4.3/5 (626 download)

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Book Synopsis Nk Cell Mediated Cytotoxicity by : Eva Lotzova

Download or read book Nk Cell Mediated Cytotoxicity written by Eva Lotzova and published by CRC Press. This book was released on 1992-03-17 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a state-of-the-art survey of developments in the field of NK cell-cancer cell interactions, activation, and oncolytic signaling. Specific topics discussed include NK cell receptors and adhesion molecules, signal transduction and activation, and mechanisms of cytotoxicity. The book will be an excellent learning tool and reference resource for scientists, clinicians, and students.

IMMUNE RESPONSES TO METASTASES

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Publisher : CRC Press
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis IMMUNE RESPONSES TO METASTASES by : Ronald B. Herberman

Download or read book IMMUNE RESPONSES TO METASTASES written by Ronald B. Herberman and published by CRC Press. This book was released on 1987 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Avian Cellular Immunology

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Publisher : Routledge
ISBN 13 : 1351464957
Total Pages : 224 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Avian Cellular Immunology by : JagdevM. Sharma

Download or read book Avian Cellular Immunology written by JagdevM. Sharma and published by Routledge. This book was released on 2018-01-29 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge regarding avian cellular immunity has expanded rapidly within the last few years and new information continues to accumulate. It is now a well-established fact that cell-mediated immunity plays a major role in the defense against neoplastic and non-neoplastic diseases in chickens. The principle objective of Avian Cellular Immunology is to compile the latest information available on various aspects of avian cellular immunity. The book contains chapters written by leading experts in the field and covers topics including cell surface markers, T-cell immunity, natural immune functions, the role of macrophages in cellular immune functions, cellular immune suppression and tolerance, cellular immune systems in avian species other than chickens, the role of cellular immunity in neoplastic and non-neoplastic viral diseases, cell-mediated immune mechanisms in bacterial and parasitic infections, and autoimmune disorders.

Mechanisms of Tumor Escape from the Immune Response

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Publisher : CRC Press
ISBN 13 : 9780415282079
Total Pages : 290 pages
Book Rating : 4.2/5 (82 download)

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Book Synopsis Mechanisms of Tumor Escape from the Immune Response by : A Ochoa

Download or read book Mechanisms of Tumor Escape from the Immune Response written by A Ochoa and published by CRC Press. This book was released on 2002-12-12 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The progressive growth of a malignant tumor is accompanied by a decline in the immune response, through mechanisms that have, until recently, been poorly understood. The new era of biological therapies, including cytokines, adoptive transfer of TIL cells, gene therapy and others, brought forth the need to understand the impact of the tumor on the immune system. Moreover, the inability to achieve in humans the unequivocal success of immunotherapy in murine models suggests the possibility that cancer can impair the development of a therapeutic immune response. Scientific and technological advances in cellular and molecular biology during the last two decades have provided new tools with which to explore the dysfunctional immune system of patients with cancer. Novel immunology concepts have provided new insights into changes occurring in tumor cells and the immune system, providing a more cohesive understanding of the process, including: *diminished or absent expression of HLA antigens and co-stimulatory molecules *arrested maturation of dentritic cells *alterations in expression of some signal transduction proteins *increased apoptosis in T and NK cells *presence of suppressor CD+4 and CD25+ T cells Mechanisms of Tumor Escape from the Immune Response provides an introduction to this rapidly developing and, as yet, unsettled area of cancer research, and will be a valuable reference for clinicians and researchers working in the field of cancer immunotherapy.

Investigation of Cell-mediated Immunity

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Author :
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Investigation of Cell-mediated Immunity by : Takeshi Yoshida

Download or read book Investigation of Cell-mediated Immunity written by Takeshi Yoshida and published by . This book was released on 1985 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: