Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

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Publisher :
ISBN 13 : 9783030372989
Total Pages : 742 pages
Book Rating : 4.3/5 (729 download)

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Book Synopsis Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses by : Loutfy H. Madkour

Download or read book Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses written by Loutfy H. Madkour and published by . This book was released on 2020 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress. Endoplasmic Reticulum (ER) Stress as a mechanism for NPs induced toxicity has been discussed. The advances of nanotechnology and the effects of nanoparticles on oxidative stress, ROS and ER stress parameters are discussed. Antioxidants, therapeutic options and regulation of the immune responses are explained throughout the book.

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms

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Publisher : Academic Press
ISBN 13 : 0128224967
Total Pages : 782 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms by : Loutfy H. Madkour

Download or read book Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms written by Loutfy H. Madkour and published by Academic Press. This book was released on 2020-06-27 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

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Author :
Publisher : Springer
ISBN 13 : 9783030372965
Total Pages : 696 pages
Book Rating : 4.3/5 (729 download)

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Book Synopsis Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses by : Loutfy H. Madkour

Download or read book Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses written by Loutfy H. Madkour and published by Springer. This book was released on 2020-03-14 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress. Endoplasmic Reticulum (ER) Stress as a mechanism for NPs induced toxicity has been discussed. The advances of nanotechnology and the effects of nanoparticles on oxidative stress, ROS and ER stress parameters are discussed. Antioxidants, therapeutic options and regulation of the immune responses are explained throughout the book.

Nanomaterials for Environmental Protection

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Publisher : John Wiley & Sons
ISBN 13 : 1118845544
Total Pages : 592 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Nanomaterials for Environmental Protection by : Boris I. Kharisov

Download or read book Nanomaterials for Environmental Protection written by Boris I. Kharisov and published by John Wiley & Sons. This book was released on 2014-08-27 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is divided into four main sections thoroughly analyzing the use of nanomaterials for water, air and soil solutions, and emphasizing environmental risks. Providing background on nanomaterials' two-decade study, it discusses the characterization and application of unconventional disinfectants, called antimicrobial nanomaterials, which fall into three categories and, while seemingly harmless, have potential hazards if applied improperly. Special attention is given to the process of remediation, synthetics techniques, and properties of nanomaterials, with examples to which new and trained readers in the field can relate and understand. an interdisciplinary approach, aimed at scientists in physical chemistry, nanotechnology, and environmental sciences includes applications of non-conventional techniques in environmental protection furthers the development of applied nanoscience and nanotechnology suggests new industrial projects and university courses addressing nanotechnology in and for the environment includes applications for water, air and soil protection

Nanoparticle Drug Delivery Systems for Cancer Treatment

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Publisher : CRC Press
ISBN 13 : 1000681416
Total Pages : 179 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Nanoparticle Drug Delivery Systems for Cancer Treatment by : Hala Gali-Muhtasib

Download or read book Nanoparticle Drug Delivery Systems for Cancer Treatment written by Hala Gali-Muhtasib and published by CRC Press. This book was released on 2020-02-19 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Bio-manufactured Nanomaterials

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Publisher : Springer Nature
ISBN 13 : 3030672239
Total Pages : 451 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Bio-manufactured Nanomaterials by : Kaushik Pal

Download or read book Bio-manufactured Nanomaterials written by Kaushik Pal and published by Springer Nature. This book was released on 2021-06-17 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the principles, limitations, challenges, improvements and applications of nanotechnology in medical science as described in the literature. It highlights various parameters affecting the synthesis of bio-nanomaterials and exclusive techniques utilized for characterizing the nanostructures for their potential use in biomedical and environmental applications. Moreover, biodegradable synthesis of nanomaterials is regarded as an important tool to reduce the destructive effects associated with the traditional methods of synthesis for nanostructures commonly utilized in laboratory and industry and as well as academic scale of innovative research foundation.

Safety and Regulatory Issues of Nanoencapsulated Food Ingredients

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Publisher : Academic Press
ISBN 13 : 0128165189
Total Pages : 316 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Safety and Regulatory Issues of Nanoencapsulated Food Ingredients by :

Download or read book Safety and Regulatory Issues of Nanoencapsulated Food Ingredients written by and published by Academic Press. This book was released on 2021-07-03 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Safety and Regulatory Issues of Nanoencapsulated Food Ingredients, a volume in the Nanoencapsulation in the Food Industry series, discusses the safety and toxicity potential of food-relevant and edible nanostructures, along with legislation issued by different countries and organizations governing their safety. The book's chapters cover safety issues of nanocapsules in food matrices, their possible toxicity effects, and in vitro and in vivo assays which are explored to underline their impact. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title is of great value to those engaged in fields surrounding nanoencapsulation. Explores how to analyze the safety of nanoencapsulated bioactive ingredients Discusses the regulations governing the safety of nanoencapsulated ingredients in different countries Investigates what agencies and which governmental organizations are responsible for the safety of nanoencapsulated ingredients

Nanostructured Materials

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Publisher : Springer Nature
ISBN 13 : 303026145X
Total Pages : 210 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Nanostructured Materials by : T. Daniel Thangadurai

Download or read book Nanostructured Materials written by T. Daniel Thangadurai and published by Springer Nature. This book was released on 2020-02-27 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the early stages of the development of nanostructures, including synthesis techniques, growth mechanisms, the physics and chemistry of nanostructured materials, various innovative characterization techniques, the need for functionalization and different functionalization methods as well as the various properties of nanostructured materials. It focuses on the applications of nanostructured materials, such as mechanical applications, nanoelectronics and microelectronic devices, nano-optics, nanophotonics and nano-optoelectronics, as well as piezoelectric, agriculture, biomedical and, environmental remediation applications, and anti-microbial and antibacterial properties. Further, it includes a chapter on nanomaterial research developments, highlighting work on the life-cycle analysis of nanostructured materials and toxicity aspects.

Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology

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Publisher : Springer Nature
ISBN 13 : 3031123980
Total Pages : 384 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology by : Seth Kwabena Amponsah

Download or read book Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology written by Seth Kwabena Amponsah and published by Springer Nature. This book was released on 2022-10-25 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges

Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

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Publisher : Bentham Science Publishers
ISBN 13 : 9815079700
Total Pages : 288 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Nanopharmacology and Nanotoxicology: Clinical Implications and Methods by : Elham Ahmadian

Download or read book Nanopharmacology and Nanotoxicology: Clinical Implications and Methods written by Elham Ahmadian and published by Bentham Science Publishers. This book was released on 2023-05-31 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading

From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials

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Author :
Publisher : MDPI
ISBN 13 : 3036501126
Total Pages : 188 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials by : Valérie Fessard

Download or read book From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials written by Valérie Fessard and published by MDPI. This book was released on 2021-03-24 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage—the first step in carcinogenesis—must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.

Nanoparticles in Medicine

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Publisher : Springer Nature
ISBN 13 : 9811389543
Total Pages : 220 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Nanoparticles in Medicine by : Ashutosh Kumar Shukla

Download or read book Nanoparticles in Medicine written by Ashutosh Kumar Shukla and published by Springer Nature. This book was released on 2019-08-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div

Interaction of Nanomaterials with the Immune System

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Publisher : Springer Nature
ISBN 13 : 3030339629
Total Pages : 229 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Interaction of Nanomaterials with the Immune System by : James C. Bonner

Download or read book Interaction of Nanomaterials with the Immune System written by James C. Bonner and published by Springer Nature. This book was released on 2020-01-30 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs.

Oxidative Stress and Biomaterials

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Publisher : Academic Press
ISBN 13 : 0128032707
Total Pages : 404 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Oxidative Stress and Biomaterials by : Thomas Dziubla

Download or read book Oxidative Stress and Biomaterials written by Thomas Dziubla and published by Academic Press. This book was released on 2016-05-31 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility

Human Immune System

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110654229
Total Pages : 189 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Human Immune System by : Shyamasree Ghosh

Download or read book Human Immune System written by Shyamasree Ghosh and published by Walter de Gruyter GmbH & Co KG. This book was released on 2022-02-21 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fast development in the field of nanotechnology has led to a high variety of nanoparticles. Nanoparticles find importance in every sphere of human lives and more so in the recent years have tremendous applications in the sector of biomedical clinical medicine as diagnostic, prognostic and imaging tools. Their risk to human and animal life as well as to the environment is still unclear. Therefore, the study of the impact of nanoparticles on human and animal life is important. Volume I highlights the impact of nanoparticles on the human immune system. While discussing the basic biology of the immune system, this book highlights the downstream effect of nanoparticles on the human immune system. Research studies on the development of better and more effective nanoparticles with more precise and accurate effects and with toxic minimal side effects are discussed in the book. Both volumes are also included in a set ISBN 978-3-11-065666-4.

Diverse Applications of Nanotechnology in the Biological Sciences

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Publisher : CRC Press
ISBN 13 : 1000564916
Total Pages : 391 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Diverse Applications of Nanotechnology in the Biological Sciences by : Khalid Rehman Hakeem

Download or read book Diverse Applications of Nanotechnology in the Biological Sciences written by Khalid Rehman Hakeem and published by CRC Press. This book was released on 2022-06-30 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diverse Applications of Nanotechnology in the Biological Sciences: An Essential Tool in Agri-Business and Health Care Systems explores the diverse roles that nanobiotechnology plays in the medical sciences, pharmacy, healthcare, and in plants and agriculture. Looking at the diverse applications of nanotechnology in the healthcare field, the chapter authors discuss its importance in drug delivery, biomedical imaging and medical diagnostics, and healthcare management. The volume emphasizes how nanomedicine can treat different types of cancers and can improve medical imaging for the diagnosis of different kinds of diseases, resulting in quicker and more accurate diagnosis and better treatment options. The volume delves into nanobiotechnology in plants and its application in nanofertilizers and nano-pesticides in agriculture. It also documents how agri-nanobiotechnology can be a tool for innovative green technology that can be applied for global food security, biodiversity, and climate change solutions. The themes of nanobiotechnology in medicine and in plants are merged in the chapter on the types and therapeutic effects of plant product-based nanomedicine for malignancies. The potential toxicity of nanoparticles in plants is also elucidated. This volume provides an insightful overview of nanobiotechnology in medicine and in plants and agriculture that will be valuable for researchers and scientists and faculty and students in the areas of nanobiotechnology, agriculture, plant molecular biology, and medicine and healthcare.

Nanoparticle-Based Drug Delivery in Cancer Treatment

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Publisher : CRC Press
ISBN 13 : 100053216X
Total Pages : 558 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Nanoparticle-Based Drug Delivery in Cancer Treatment by : Loutfy H. Madkour

Download or read book Nanoparticle-Based Drug Delivery in Cancer Treatment written by Loutfy H. Madkour and published by CRC Press. This book was released on 2022-03-03 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Focuses on material platforms that establish NPs and both localized and controlled gene silencing Emphasizes the most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment Describes the most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.