Nanofocusing Refractive X-Ray Lenses

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (652 download)

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Book Synopsis Nanofocusing Refractive X-Ray Lenses by :

Download or read book Nanofocusing Refractive X-Ray Lenses written by and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis is concerned with the optimization and development of the production of nanofocusing refractive x-ray lenses. These optics made of either silicon or diamond are well-suited for high resolution x-ray microscopy. The goal of this work is the design of a reproducible manufacturing process which allows the production of silicon lenses with high precision, high quality and high piece number. Furthermore a process for the production of diamond lenses is to be developed and established. In this work, the theoretical basics of x-rays and their interaction with matter are described. Especially, aspects of synchrotron radiation are emphasized. Important in x-ray microscopy are the different optics. The details, advantages and disadvantages, in particular those of refractive lenses are given. To achieve small x-ray beams well beyond the 100nm range a small focal length is required. This is achieved in refractive lenses by moving to a compact lens design where several single lenses are stacked behind each other. The, so-called nanofocusing refractive lenses (NFLs) have a parabolic cylindrical shape with lateral structure sizes in the micrometer range. NFLs are produced by using micro-machining techniques. These micro-fabrication processes and technologies are introduced. The results of the optimization and the final fabrication process for silicon lenses are presented. Subsequently, two experiments that are exemplary for the use of NFLs, are introduced. The first one employs a high-resolution scanning fluorescence mapping of a geological sample, and the second one is a coherent x-ray diffraction imaging (CXDI) experiment. CXDI is able to reconstruct the illuminated object from recorded coherent diffraction patterns. In a scanning mode, referred to as ptychography, this method is even able to reconstruct the illumination and the object simultaneously. Especially the reconstructed illumination and the possibility of computed propagation of the wavefield along the focu.

Hard X-Ray Scanning Microscope Using Nanofocusing Parabolic Refractive Lenses

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Author :
Publisher : Cuvillier Verlag
ISBN 13 : 3736936141
Total Pages : 164 pages
Book Rating : 4.7/5 (369 download)

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Book Synopsis Hard X-Ray Scanning Microscope Using Nanofocusing Parabolic Refractive Lenses by : Jens Patommel

Download or read book Hard X-Ray Scanning Microscope Using Nanofocusing Parabolic Refractive Lenses written by Jens Patommel and published by Cuvillier Verlag. This book was released on 2011-01-24 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hard x rays come along with a variety of extraordinary properties which make them an excellent probe for investigation in science, technology and medicine. Their large attenuation length in matter opens up the possibility to use hard x-rays for non-destructive investigation of the inner structure of specimens. Medical radiography is one important example of exploiting this feature. Since their discovery by W. C. Röntgen in 1895, a large variety of x-ray analytical techniques have been developed and successfully applied, such as x-ray crystallography, reflectometry, fluorescence spectroscopy, x-ray absorption spectroscopy, small angle x-ray scattering, and many more. Each of those methods reveals information about certain physical properties, but usually, these properties are an average over the complete sample region illuminated by the x rays. In order to obtain the spatial distribution of those properties in inhomogeneous samples, scanning microscopy techniques have to be applied, screening the sample with a small x-ray beam. The spatial resolution is limited by the finite size of the beam. The availability of highly brilliant x-ray sources at third generation synchrotron radiation facilities together with the development of enhanced focusing x-ray optics made it possible to generate increasingly small high intense x-ray beams, pushing the spatial resolution down to the sub-100nm range. During this thesis the prototype of a hard x-ray scanning microscope utilizing microstructured nanofocusing lenses was designed, built, and successfully tested. The nanofocusing x-ray lenses were developed by our research group of the Institute of Structural Physics at the Technische Universität Dresden. The prototype instrument was installed at the ESRF beamline ID 13. A wide range of experiments like fluorescence element mapping, fluorescence tomography, x-ray nano-diffraction, coherent x-ray diffraction imaging, and x-ray ptychography were performed as part of this thesis. The hard x-ray scanning microscope provides a stable x-ray beam with a full width at half maximum size of 50–100nm near the focal plane. The nanoprobe was also used for characterization of nanofocusing lenses, crucial to further improve them. Based on the experiences with the prototype, an advanced version of a hard x-ray scanning microscope is under development and will be installed at the PETRA III beamline P06 dedicated as a user instrument for scanning microscopy. This document is organized as follows. A short introduction motivating the necessity for building a hard x-ray scanning microscope is followed by a brief review of the fundamentals of hard x-ray physics with an emphasis on free-space propagation and interaction with matter. After a discussion of the requirements on the x-ray source for the nanoprobe, the main features of synchrotron radiation from an undulator source are shown. The properties of the nanobeam generated by refractive x-ray lenses are treated as well as a two-stage focusing scheme for tailoring size, flux and the lateral coherence properties of the x-ray focus. The design and realization of the microscope setup is addressed, and a selection of experiments performed with the prototype version is presented, before this thesis is finished with a conclusion and an outlook on prospective plans for an improved microscope setup to be installed at PETRA III.

Nanofocusing Refractive X-ray Lenses

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Publisher :
ISBN 13 :
Total Pages : 145 pages
Book Rating : 4.:/5 (68 download)

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Book Synopsis Nanofocusing Refractive X-ray Lenses by : Pit Boye

Download or read book Nanofocusing Refractive X-ray Lenses written by Pit Boye and published by . This book was released on 2009 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Development of Nanofocusing Refractive X-ray Lenses

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Development of Nanofocusing Refractive X-ray Lenses by : Olga Kurapova

Download or read book Development of Nanofocusing Refractive X-ray Lenses written by Olga Kurapova and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Wave Optical Simulations of X-ray Nano-focusing Optics

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Publisher : Universitätsverlag Göttingen
ISBN 13 : 3863950542
Total Pages : 167 pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis Wave Optical Simulations of X-ray Nano-focusing Optics by : Markus Osterhoff

Download or read book Wave Optical Simulations of X-ray Nano-focusing Optics written by Markus Osterhoff and published by Universitätsverlag Göttingen. This book was released on 2012 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Curved x-ray multilayer mirrors focus synchrotron beams down to tens of nano metres. A wave-optical theory describing propagation of two waves in an elliptically curved focusing multilayer mirror is developed in this thesis. Using numerical integration, the layer shapes can be optimised for reflectivity and aberrations. Within this framework, performance of both existing and currently upgraded synchrotron beamlines is simulated. Using a more theoretical model case, limits of the theory are studied. A significant part of this work is dedicated to partial spatial coherence, modelled using the method of stochastic superpositions. Coherence propagation and filtering by x-ray waveguides is shown analytically and numerically. This comprehensive model is put forward that shall help in development and testing of new algorithms for a variety of imaging techniques using coherent x-ray beams. Advanced simulations accounting for real structure effects are compared to experimental data obtained at the GINIX instrument at the coherence beamline P10 at PETRA III, DESY. This thesis presents results of a collaboration between the Georg-August-Universität Göttingen and the European Synchrotron Radiation Facility (ESRF) Grenoble.

Design and Microfabrication of Novel X-ray Optics II

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Publisher : SPIE-International Society for Optical Engineering
ISBN 13 :
Total Pages : 278 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Design and Microfabrication of Novel X-ray Optics II by : Anatoly A. Snigirev

Download or read book Design and Microfabrication of Novel X-ray Optics II written by Anatoly A. Snigirev and published by SPIE-International Society for Optical Engineering. This book was released on 2004 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

X-ray Micro- and Nano-focusing

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Publisher : SPIE-International Society for Optical Engineering
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis X-ray Micro- and Nano-focusing by : Ian McNulty

Download or read book X-ray Micro- and Nano-focusing written by Ian McNulty and published by SPIE-International Society for Optical Engineering. This book was released on 2001 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanoscale Photonic Imaging

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Publisher : Springer Nature
ISBN 13 : 3030344134
Total Pages : 634 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Nanoscale Photonic Imaging by : Tim Salditt

Download or read book Nanoscale Photonic Imaging written by Tim Salditt and published by Springer Nature. This book was released on 2020-06-09 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book, edited and authored by a team of world-leading researchers, provides a broad overview of advanced photonic methods for nanoscale visualization, as well as describing a range of fascinating in-depth studies. Introductory chapters cover the most relevant physics and basic methods that young researchers need to master in order to work effectively in the field of nanoscale photonic imaging, from physical first principles, to instrumentation, to mathematical foundations of imaging and data analysis. Subsequent chapters demonstrate how these cutting edge methods are applied to a variety of systems, including complex fluids and biomolecular systems, for visualizing their structure and dynamics, in space and on timescales extending over many orders of magnitude down to the femtosecond range. Progress in nanoscale photonic imaging in Göttingen has been the sum total of more than a decade of work by a wide range of scientists and mathematicians across disciplines, working together in a vibrant collaboration of a kind rarely matched. This volume presents the highlights of their research achievements and serves as a record of the unique and remarkable constellation of contributors, as well as looking ahead at the future prospects in this field. It will serve not only as a useful reference for experienced researchers but also as a valuable point of entry for newcomers.

X-Ray Microscopy

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Publisher : Cambridge University Press
ISBN 13 : 1107076579
Total Pages : 594 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis X-Ray Microscopy by : Chris Jacobsen

Download or read book X-Ray Microscopy written by Chris Jacobsen and published by Cambridge University Press. This book was released on 2019-12-19 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete introduction to x-ray microscopy, covering optics, 3D and chemical imaging, lensless imaging, radiation damage, and applications.

X-ray waveguide optics

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Publisher : Göttingen University Press
ISBN 13 : 3863953088
Total Pages : 134 pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis X-ray waveguide optics by : Sarah Hoffmann-Urlaub

Download or read book X-ray waveguide optics written by Sarah Hoffmann-Urlaub and published by Göttingen University Press. This book was released on 2017 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern x-ray sources and analysis techniques such as lens less imaging combined with phase retrieval algorithms allow for resolving structure sizes in the nanometer range. For this purpose optics have to be employed, ensuring small focal spot dimensions simultaneously with high photon densities. Furthermore, the wave front behind the optics is required to be smooth enabling for high resolution imaging. Combining all these properties, x-ray waveguides are well suited to perform this task, since the intensity distribution behind the guide is restricted in two dimensions serving as a secondary quasi point-source without wave-front aberrations, showing also a high divergence, suitable for resolving fine features. Importantly, the radiation provided by the waveguide reveals a high degree of coherence, required by many imaging techniques. The waveguide itself consists of an air-filled channel embedded in a solid matrix; typical materials are silicon, germanium or quartz. While the entrance area is nano-sized, the channel length is in the millimeter-range, this way posing challenges to fabricate high aspect ratio geometries. Since the functioning of x-ray waveguides is based on the total reflection at small incident angles, the surface roughness of the channel walls must be as low as possible to avoid scattering and hence loss of intensity. To fulfill these demanding conditions, a process scheme involving spin-coating, electron beam lithography, wet development, reactive ion etching and wafer bonding is optimized within this work. To gain deeper insights into the principle of wave guiding finite difference simulations are performed, also opening access for advanced design considerations such as gratings, tapered and curved channels, or beamsplitters, enabling for constructing novel x-ray tools as for example time delay devices or interferometers. Waveguides in all geometries are tested at synchrotron sources, accomplishing new benchmarks in x-ray optical performance. Here, the x-ray beam leaving the channel, propagates out to a pixel array detector in the far-field region. From the recorded data the intensity distribution in the near-field directly behind the waveguide is reconstructed, revealing an outstanding agreement with the simulations and electron micrographs. Since the radiation field of the waveguide is well-characterized and also tunable to meet the requirements of both the measurement setup and the sample, they are suited of a broad field of applications in coherent x-ray imaging.

Micro- and Nano-Fabrication by Metal Assisted Chemical Etching

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Publisher : MDPI
ISBN 13 : 303943845X
Total Pages : 106 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Micro- and Nano-Fabrication by Metal Assisted Chemical Etching by : Lucia Romano

Download or read book Micro- and Nano-Fabrication by Metal Assisted Chemical Etching written by Lucia Romano and published by MDPI. This book was released on 2021-01-13 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-assisted chemical etching (MacEtch) has recently emerged as a new etching technique capable of fabricating high aspect ratio nano- and microstructures in a few semiconductors substrates—Si, Ge, poly-Si, GaAs, and SiC—and using different catalysts—Ag, Au, Pt, Pd, Cu, Ni, and Rh. Several shapes have been demonstrated with a high anisotropy and feature size in the nanoscale—nanoporous films, nanowires, 3D objects, and trenches, which are useful components of photonic devices, microfluidic devices, bio-medical devices, batteries, Vias, MEMS, X-ray optics, etc. With no limitations of large-areas and low-cost processing, MacEtch can open up new opportunities for several applications where high precision nano- and microfabrication is required. This can make semiconductor manufacturing more accessible to researchers in various fields, and accelerate innovation in electronics, bio-medical engineering, energy, and photonics. Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on novel methodological developments in MacEtch, and its use for various applications.

MicroComputed Tomography

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Publisher : CRC Press
ISBN 13 : 0429532466
Total Pages : 424 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis MicroComputed Tomography by : Stuart R. Stock

Download or read book MicroComputed Tomography written by Stuart R. Stock and published by CRC Press. This book was released on 2019-12-20 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroComputed Tomography has become the gold standard for studying 3D microscopic structures nondestructively, and this book provides up-to-date coverage of the modality. The first part of the book focuses on methodology, covering experimental methods, data analysis, and visualization approaches. Emphasis is on fundamentals so that those new to the field can design their own effective microCT studies. The second part addresses various microCT applications, organized by type of microstructure so that the reader can appreciate approaches from other disciplines. The applications include porous solids, microstructural evolution, soft tissue studies, applications using x-ray phase contrast or x-ray scattering contrast, and multimode studies.

Coherent X-Ray Optics

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Publisher : OUP Oxford
ISBN 13 : 019152431X
Total Pages : 424 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Coherent X-Ray Optics by : David Paganin

Download or read book Coherent X-Ray Optics written by David Paganin and published by OUP Oxford. This book was released on 2006-01-12 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a thorough treatment of the rapidly-expanding field of coherent x-ray optics, which has recently experienced something of a renaissance with the availability of third-generation synchrotron sources. It is the first book of its kind. The author begins with a treatment of the fundamentals of x-ray diffraction for both coherent and partially coherent radiation, together with the interactions of x-rays with matter. X-ray sources, optics elements and detectors are then discussed, with an emphasis on their role in coherent x-ray optics. Various facets of coherent x-ray imaging are then discussed, including holography, interferometry, self imaging, phase contrast and phase retrieval. Lastly, the foundations of the new field of singular x-ray optics are examined. Most topics are developed from first principles, with numerous references given to the contemporary research literature. This book will be useful to x-ray physicists and students, together with optical physicists and engineers who wish to learn more about the fascinating subject of coherent x-ray optics.

X-ray optics made by X-ray lithography: Process optimization and quality control

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Author :
Publisher : KIT Scientific Publishing
ISBN 13 : 3731506793
Total Pages : 168 pages
Book Rating : 4.7/5 (315 download)

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Book Synopsis X-ray optics made by X-ray lithography: Process optimization and quality control by : Koch, Frieder Johannes

Download or read book X-ray optics made by X-ray lithography: Process optimization and quality control written by Koch, Frieder Johannes and published by KIT Scientific Publishing. This book was released on 2017-10-16 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Grating based X-ray phase contrast imaging sets out to overcome the limits of conventional X-ray imaging in the detection of subtle density differences and opens a way to characterize a sample's microstructure without the need for ultrahigh spatial resolution. The technique relies on grating structures with micrometric periods and extreme aspect ratio - their fabrication by X-ray lithography with optimal structure quality is the topic of this work.

Physics of and Science with X-Ray Free-Electron Lasers

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Publisher : IOS Press
ISBN 13 : 1643681338
Total Pages : 272 pages
Book Rating : 4.6/5 (436 download)

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Book Synopsis Physics of and Science with X-Ray Free-Electron Lasers by : J. Hastings

Download or read book Physics of and Science with X-Ray Free-Electron Lasers written by J. Hastings and published by IOS Press. This book was released on 2020-12-18 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many X-Ray Free-Electron Lasers (X-FELs) have been designed, built and commissioned since the first lasing of the Linac Coherent Light Source in the hard and soft X-ray regions, and great progress has been made in improving their performance and extending their capabilities. Meanwhile, experimental techniques to exploit the unique properties of X-FELs to explore atomic and molecular systems of interest to physics, chemistry, biology and the material sciences have also been developed. As a result, our knowledge of atomic and molecular science has been greatly extended. Nevertheless, there is still much to be accomplished, and the potential for discovery with X-FELs is still largely unexplored. The next generation of scientists will need to be well versed in both particle beams/FEL physics and X-ray photon science. This book presents material from the Enrico Fermi summer school: Physics of and Science with X-Ray Free-Electron Lasers, held at the Enrico Fermi International School of Physics in Varenna, Italy, from 26 June - 1 July 2017. The lectures presented at the school were aimed at introducing graduate students and young scientists to this fast growing and exciting scientific area, and subjects covered include basic accelerator and FEL physics, as well as an introduction to the main research topics in X-FEL-based biology, atomic molecular optical science, material sciences, high-energy density physics and chemistry. Bridging the gap between accelerator/FEL physicists and scientists from other disciplines, the book will be of interest to all those working in the field.

Investigating Cellular Nanoscale with X-rays

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Publisher : Göttingen University Press
ISBN 13 : 3863952871
Total Pages : 192 pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis Investigating Cellular Nanoscale with X-rays by : Clément Hémonnot

Download or read book Investigating Cellular Nanoscale with X-rays written by Clément Hémonnot and published by Göttingen University Press. This book was released on 2016 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances and technical improvements of X-ray imaging techniques, taking advantage of X-ray focussing optics and high intensity synchrotron sources, nowadays allow for the use of X-rays to probe the cellular nanoscale. Importantly, X-rays permit thick samples to be imaged without sectioning or slicing. In this work, two macromolecules, namely keratin intermediate filament (IF) proteins and DNA, both essential components of cells, were studied by X-ray techniques. Keratin IF proteins make up an integral part of the cytoskeleton of epithelial cells and form a dense intracellular network of bundles. This network is built from monomers in a hierarchical fashion. Thus, the keratin structure formation spans a large range of length scales from a few nanometres (monomers) to micrometres (networks). Here, keratin was studied at three different scales: i) filaments, ii) bundles and iii) networks. Solution small-angle X-ray scattering revealed distinct structural and organisational characteristics of these highly charged polyelectrolyte filaments, such as increasing radius with increasing salt concentration and spatial accumulation of ions depending on the salt concentration. The results are quantified by employing advanced modelling of keratin IFs by a core cylinder fl anked with Gaussian chains. Scanning micro- diffraction was used to study keratin at the bundle scale. Very different morphologies of keratin bundles were observed at different salt conditions. At the network scale, new imaging approaches and analyses were applied to the study of whole cells. Ptychography and scanning X-ray nano-diffraction imaging were performed on the same cells, allowing for high resolution in real and reciprocal space, thereby revealing the internal structure of these networks. By using a fitting routine based on simulations of IFs packed on a hexagonal lattice, the radius of each fi lament and distance between fi laments were retrieved. In mammalian cells, each nucleus contains 2 nm-thick DNA double helices with a total length of about 2 m. The DNA strands are packed in a highly hierarchical manner into individual chromosomes. DNA was studied in intact cells by visible light microscopy and scanning X-ray nano-diffraction, unveiling the compaction und decompaction of DNA during the cell cycle. Thus, we obtained information on the aggregation state of the nuclear DNA at a real space resolution on the order of few hundreds nm. To exploit to the reciprocal space information, individual diffraction patterns were analysed according to a generalised Porod’s law at a resolution down to 10 nm. We were able to distinguish nucleoli, heterochromatin and euchromatin in the nuclei and follow the compaction and decompaction during the cell division cycle.

Optimization of Waveguide Optics for Lensless X-ray Imaging

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Author :
Publisher : Universitätsverlag Göttingen
ISBN 13 : 3863950151
Total Pages : 169 pages
Book Rating : 4.8/5 (639 download)

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Book Synopsis Optimization of Waveguide Optics for Lensless X-ray Imaging by : Sven Philip Krüger

Download or read book Optimization of Waveguide Optics for Lensless X-ray Imaging written by Sven Philip Krüger and published by Universitätsverlag Göttingen. This book was released on 2011 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lensless x-ray imaging is a promising method to determine the three-dimensional structure of material science and biological specimens at the nanoscale. The development of this technique is strongly related to the optimization of x-ray optics since the image formation and object reconstruction depend significantly on the properties of the illumination wave-field. Waveguide optics act as quasi-point sources and enable the spatial and coherent filtering of x-ray beams. Up to now, x-ray waveguides were severely limited in transmission and flux, restricting their use to high-contrast test structures with moderate resolution and long accumulation times. To overcome these limitations, a novel waveguide design with an optimized refractive index profile is presented which significantly minimizes the absorption of the modes propagating inside the waveguide. Experimental results along with simulations show that these two-component planar x-ray waveguides provide small beam cross-sections along with a high photon flux at the exit. By a serial arrangement of two waveguide slices an optimized illumination source has been developed for high-resolution microscopy, as demonstrated in proof-of-concept imaging experiments.