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Nacl Transport In Epithelia
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Book Synopsis NaCl Transport in Epithelia by : R. Greger
Download or read book NaCl Transport in Epithelia written by R. Greger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.
Book Synopsis NaCl Transport in Epithelia by : R. Greger
Download or read book NaCl Transport in Epithelia written by R. Greger and published by Springer. This book was released on 1988-05-30 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.
Book Synopsis Basic Epithelial Ion Transport Principles and Function by : Kirk L. Hamilton
Download or read book Basic Epithelial Ion Transport Principles and Function written by Kirk L. Hamilton and published by Springer Nature. This book was released on 2020-11-26 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike.
Book Synopsis Epithelial Transport by : N.K. Wills
Download or read book Epithelial Transport written by N.K. Wills and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building from general principles, the authors clearly explain the fundamental role of epithelia in plasma electrolyte and water balance. Emphasis is placed on experimental approaches and methodology. A comprehensive glossary of terms is included.
Book Synopsis Transporting Epithelia by : Michael Berridge
Download or read book Transporting Epithelia written by Michael Berridge and published by Elsevier. This book was released on 2012-12-02 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transporting Epithelia summarizes the progress that has been made in understanding a wide range of epithelial transport systems. This book discusses the epithelia involved in osmotic and ionic regulation from protonephridia to the mammalian kidney. It also explains the digestive and absorptive epithelia, as well as the epithelia that produce special secretions, such as milk, endolymph, aqueous humor, cerebrospinal fluid, sweat, and tears. Furthermore, this book describes the role of the epithelium in the physiology of the animal and the structure of the epithelium. Then, the structure of the epithelium is correlated with its physiological properties. This book will be valuable both for teaching and as a reference for research workers interested in comparative aspects of transport phenomena.
Book Synopsis Amiloride and Epithelial Sodium Transport by : Alan William Cuthbert
Download or read book Amiloride and Epithelial Sodium Transport written by Alan William Cuthbert and published by Urban & Schwarzenberg. This book was released on 1979 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NaCl Transport in Epithelia by : R. Greger
Download or read book NaCl Transport in Epithelia written by R. Greger and published by Springer. This book was released on 1988-05-30 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the pioneering studies by Ussing and co-workers, studies of epithelial Nael transport have come a long way. The first phase of the phenomenological description of the cell as a black box has been follow ed by studies of cellular mechanisms, the interplay of the different trans port components, and the mechanisms of regulation. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia. This aspect triggered the publica tion of this book, and in fact the various chapters emphasize that the funetional eomponents, expressed in the various epithelia, are not in finite in number, but they occur in epithelia which are separated in evolu tion by several hundred million years. The authors come both from the field of veterinary and human physiology as weIl as from biology. In my opinion, the close contacts and eollaborations between physiologists and biologists have been essential for the progress in this field. I wish to thank all authors for their con tributions, and I hope that the reader will appreciate this collection of up to date reviews on epithelia in nonvertebrates and vertebrates.
Book Synopsis Ion Transport by Epithelia by : Stanley G. Schultz
Download or read book Ion Transport by Epithelia written by Stanley G. Schultz and published by Raven Press (ID). This book was released on 1981 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chloride Transport Coupling in Biological Membranes and Epithelia by : George A. Gerencser
Download or read book Chloride Transport Coupling in Biological Membranes and Epithelia written by George A. Gerencser and published by Elsevier Publishing Company. This book was released on 1984 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Epithelial Transport Physiology by : George A. Gerencser
Download or read book Epithelial Transport Physiology written by George A. Gerencser and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological cell membranes regulate the transfer of matter and information between the intracellular and extracellular compartments as basic survival and maintenance functions for an organism. This volume contains a series of reviews that are c- cerned with how epithelial plasma membranes regulate the transport of solutes between the intracellular and extracellular compartments of a cell. This book is also an attempt to analyze the molecular basis for the movement of various solutes across an epithelial cell membrane. This volume is devoted to a diversity of epithelial transport mechanisms in rep- sentative cell membranes of a variety of living things. The ?rst section of the book (Chapters 1–6) focuses on mechanisms of solute transport in epithelia of inver- brates. The last section which comprises ten chapters (Chapters 7–16) deals with solute transporters in epithelial cell membranes of vertebrates. It is hoped that with this particular ordering the reader can glean a telescopic view of the evolutionary history of the various epithelial solute transporters.
Book Synopsis Transcellular Transport of Sodium and Chloride in Cultured Intestinal Epithelial Cells by : Susan Alice Levine
Download or read book Transcellular Transport of Sodium and Chloride in Cultured Intestinal Epithelial Cells written by Susan Alice Levine and published by . This book was released on 1991 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ion Channels and Transporters of Epithelia in Health and Disease by : Kirk L. Hamilton
Download or read book Ion Channels and Transporters of Epithelia in Health and Disease written by Kirk L. Hamilton and published by Springer. This book was released on 2015-12-14 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.
Book Synopsis Transport Mechanisms in Epithelia by : Hans H. Ussing
Download or read book Transport Mechanisms in Epithelia written by Hans H. Ussing and published by . This book was released on 1973 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chloride Transport by Tracheal Epithelium by : Peying Fong
Download or read book Chloride Transport by Tracheal Epithelium written by Peying Fong and published by . This book was released on 1989 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis NaCl Transport in a High Resistance Epithelium by : Erik Hviid Larsen
Download or read book NaCl Transport in a High Resistance Epithelium written by Erik Hviid Larsen and published by . This book was released on 1988 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Sodium Transport Across Epithelia Derived from Human Mammary Gland by : Qian Wang
Download or read book Regulation of Sodium Transport Across Epithelia Derived from Human Mammary Gland written by Qian Wang and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The first aim of this project is to define the cellular mechanisms that account for the low Na concentration in human milk. MCF10A cells, which were derived from human mammary epithelium and grown on permeable supports, exhibit amiloride- and benzamil-sensitive short circuit current (I[subscript]sc), suggesting activity of the epithelial Na channel, ENaC. When cultured in the presence of cholera toxin (Ctx), MCF10A cells exhibit greater amiloride sensitive I[subscript]sc at all time points tested, an effect that is not reduced with Ctx washout for 12 hours or by cytosolic pathways inhibitors. Ctx increases the abundance of both [beta] and [gamma]-ENaC in the apical membrane and increases its monoubiquitination but without changing total protein and mRNA levels. Additionally, Ctx increases the levels of both the phosphorylated and the nonphosphorylated forms of Nedd4-2, a ubiquitin-protein ligase that regulates ENaC degradation. The results reveal a novel mechanism in human mammary gland epithelia by which Ctx regulates ENaC-mediated Na+ transport. The second project aim is to develop a protocol to isolate mammary gland epithelia for subsequent in vitro culture. Caprine (1° CME) and bovine mammary epithelia (1° BME) were isolated and cultured on permeable supports to study hormone- and neurotransmitter-sensitive ion transport. Both 1° CME and 1° BME cells were passed for multiple subcultures and all passages formed electrically tight barriers. 1° CME were cultured in the presence of hydrocortisone and exhibited high electrical resistance and amiloride-sensitive I[subscript]sc, suggesting the presence of ENaC-mediated Na+ transport. 1° BME were grown in a complex media in the presence or absence of dexamethasone. In contrast to 1° CME, 1° BME exhibited no detectable amiloride-sensitive I[subscript]sc in either culture condition. However, 1° BME monolayers responded to an adrenergic agonist, norepinephrine, and a cholinergic agonist, carbamylcholine, with rapid increases in I[subscript]sc. Thus, this protocol for isolation and primary cell culture can be used for future studies that focus on mammary epithelial cell regulation and functions. In conclusion, the results from these projects demonstrate that mammary epithelial cells form electrically tight monolayers and can exhibit neurotransmitter- and/or hormone-induced net ion transport. The mechanisms that regulate Na+ transport across mammary gland may provide clues to prevent or treat mastitis.
Book Synopsis Epithelial Sodium Transport by : Ayus Corcia
Download or read book Epithelial Sodium Transport written by Ayus Corcia and published by . This book was released on 1981 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
