Myocardial Protection And The Katp Channel

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Myocardial Protection and the KATP Channel

Author : Derek Yellon
Publisher : Springer Science & Business Media
ISBN 13 : 9780792337911
Total Pages : 232 pages
Book Rating : 4.3/5 (379 download)

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Book Synopsis Myocardial Protection and the KATP Channel by : Derek Yellon

Download or read book Myocardial Protection and the KATP Channel written by Derek Yellon and published by Springer Science & Business Media. This book was released on 1995-12-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ATP-sensitive potassium channel (KATP) was discovered in 1983. Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection. To this end, the editors have assembled investigators at the forefront of ongoing basic and clinical research to provide scholarly and candid comments concerning each of the pertinent issues, including: a comprehensive review of the biology of the channel with respect to the structure-activity relationship as well as overall chemistry of the channel; the role of opening this channel and its effect on smooth muscle (covering both the effects on myocardial stunning and its ability to protect against myocardial infarction); the relationship of KATP channel opening and the protection to the myocardium afforded by the phenomenon of ischemic preconditioning; the relationship between the KATP channel and electrophysiological consequences with specific reference to arrhythmogenicity; and the clinical implications of the use of agents that mimic the opening of this channel, with reference to its protective nature and its use in the treatment of angina. Audience: Clinicians and basic scientists who have a direct interest in the KATP channel as well as those groups who are interested in the entire concept of myocardial protection and its relationship to academic and clinical medicine.

Purines and Myocardial Protection

Author : Anwar-Saad A. Abd-Elfattah
Publisher : Springer Science & Business Media
ISBN 13 : 9780792338314
Total Pages : 596 pages
Book Rating : 4.3/5 (383 download)

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Book Synopsis Purines and Myocardial Protection by : Anwar-Saad A. Abd-Elfattah

Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 1996-01-31 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Myocardial Protection

Author : Tomas A. Salerno
Publisher : Wiley-Blackwell
ISBN 13 : 9781405116435
Total Pages : 344 pages
Book Rating : 4.1/5 (164 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by Wiley-Blackwell. This book was released on 2003-12-12 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Electrical Diseases of the Heart

Author : Ihor Gussak
Publisher : Springer Science & Business Media
ISBN 13 : 1447148819
Total Pages : 661 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Electrical Diseases of the Heart by : Ihor Gussak

Download or read book Electrical Diseases of the Heart written by Ihor Gussak and published by Springer Science & Business Media. This book was released on 2013-04-22 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

Myocardial Protection

Author : Tomas A. Salerno
Publisher : John Wiley & Sons
ISBN 13 : 1405178434
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Purines and Myocardial Protection

Author : Anwar-Saad A. Abd-Elfattah
Publisher : Springer Science & Business Media
ISBN 13 : 1461304555
Total Pages : 565 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Purines and Myocardial Protection by : Anwar-Saad A. Abd-Elfattah

Download or read book Purines and Myocardial Protection written by Anwar-Saad A. Abd-Elfattah and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Heat Shock Proteins in Myocardial Protection

Author : Rakesh C. Kukreja
Publisher : CRC Press
ISBN 13 : 1498712665
Total Pages : 115 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Heat Shock Proteins in Myocardial Protection by : Rakesh C. Kukreja

Download or read book Heat Shock Proteins in Myocardial Protection written by Rakesh C. Kukreja and published by CRC Press. This book was released on 2000-08-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial ischemic syndromes pose a major medical problem and a significant economic health care concern. Reperfusion, although used in the clinical arena as essential to the survival of acutely ischemic heart muscle carries with it the risk of "reperfusion injury". Therefore the salvage of additional myocardium is highly desirable. Over a decade ago, it was shown that whole body heat shock activated a powerful endogenous protective mechanism that significantly improved myocardial salvage following prolonged ischemia and reperfusion injury in the heart. A characteristic feature of this heat shock response was the expression of a family of proteins known as heat shock proteins. Many of these proteins function as molecular chaperones, helping to refold proteins denatured as a consequence of lethal injuries and facilitating the synthesis of new proteins to replace those irreparably damaged. Altered expression of these proteins has been extensively documented in association with a diverse array of diseases such as ischemia and perfusion injury, cardiac hypertrophy, fever, inflammation, metabolic diseases, infection, cell and tissue trauma, aging, and cancer. Interestingly, some studies have now shown a direct correlation of the heat shock proteins produced and the degree of myocardial protection. This book is a thorough description of the current state of knowledge of the mechanisms of heat shock proteins induced cardiac protection at the cellular and molecular level, the controversies in this growing field and the potential of treating ischemic heart disease with overexpression of heat shock proteins in patients. The book will be especially useful for investigators interested in studying tissue injury and its protection with the overexpression of heat shock proteins.

Cardiopulmonary Bypass

Author : Sunit Ghosh
Publisher : Cambridge University Press
ISBN 13 : 1107428254
Total Pages : 271 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Cardiopulmonary Bypass by : Sunit Ghosh

Download or read book Cardiopulmonary Bypass written by Sunit Ghosh and published by Cambridge University Press. This book was released on 2015-11-26 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete clinically orientated guide to cardiopulmonary bypass and extracorporeal support for trainee medical and technical personnel in cardiac surgery.

Myocardial Protection in Cardiac Surgery

Author : Arthur James Roberts
Publisher : CRC Press
ISBN 13 : 9780824776381
Total Pages : 640 pages
Book Rating : 4.7/5 (763 download)

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Book Synopsis Myocardial Protection in Cardiac Surgery by : Arthur James Roberts

Download or read book Myocardial Protection in Cardiac Surgery written by Arthur James Roberts and published by CRC Press. This book was released on 1987-04-27 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Myocardial Preservation and Cellular Adaptation

Author : D.K. Das
Publisher : Elsevier
ISBN 13 : 9780080877235
Total Pages : 274 pages
Book Rating : 4.8/5 (772 download)

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Book Synopsis Myocardial Preservation and Cellular Adaptation by : D.K. Das

Download or read book Myocardial Preservation and Cellular Adaptation written by D.K. Das and published by Elsevier. This book was released on 1998-12-18 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living organisms exhibit specific responses when confronted with sudden changes in their environmental conditions. The ability of the cells to acclimate to their new environment is the integral driving force for adaptive modification of the cells. Such adaptation involves a number of cellular and biochemical alteration including metabolic homeostasis and reprogramming of gene expression. Changes in metabolic pathways are generally short-lived and reversible, while the consequences of gene expression are a long-term process and may lead to permanent alternation in the pattern of adaptive responses. The heart possesses remarkable ability to adapt itself against any stressful situation by increasing resistance to the adverse consequences. Stress composes the foundation of many degenerative heart diseases including atherosclerosis, spasm, thrombosis, cardiomyopathy, and congestive heart failure. Based on the concept that excessive stress may play a crucial role in the pathogenesis of ischemic heart disease, attempts were made to design methods for preventing of myocardial injury. Creation of stress reactions by repeated ischemia and reperfusion or subjecting the hearts to heat or oxidative stress enables them to meet the future stress challenge. Repeated stress exposures adapt the heart to withstand more severe stress reactions probably by upregulating the cellular defense and direct accumulation of intracellular mediators, which presumably constitute the material basis of increased adaptation to stress. Thus, the powerful cardioprotective effect of adaptation is likely to originate at the cellular and molecular levels that compose fundamental processes in the prophylaxis of such diseases. Volume six of the Advances in Organ Biology series contains state-of-the-art reviews on myocardial preservation and cellular adaptation from the leading authorities in this subject.

Handbook of Cardiac Anatomy, Physiology, and Devices

Author : Paul A. Iaizzo
Publisher : Springer
ISBN 13 : 331919464X
Total Pages : 817 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Handbook of Cardiac Anatomy, Physiology, and Devices by : Paul A. Iaizzo

Download or read book Handbook of Cardiac Anatomy, Physiology, and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.

Author : A. Gullo
Publisher : Springer Science & Business Media
ISBN 13 : 8847020999
Total Pages : 1183 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E. by : A. Gullo

Download or read book Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E. written by A. Gullo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic research, progress in technology and informatics, and the success of clinical pharmacology are the fundamental bases of this interesting field of medicine. Nowadays, critical care medicine is no longer for experts only, but it is a field in which researchers and clinicians, nurses and technical staff work in an interdisciplinary way, each offering their own skills. The volume is divided in six sections, devoted to critical care key issues, to lung diseases, to trauma, to acid-base equilibrium, to perioperative medicine, and to obstetrics.

Heart Physiology and Pathophysiology

Author : Yoshihisa Kurachi
Publisher : Elsevier
ISBN 13 : 0080533884
Total Pages : 1286 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Heart Physiology and Pathophysiology by : Yoshihisa Kurachi

Download or read book Heart Physiology and Pathophysiology written by Yoshihisa Kurachi and published by Elsevier. This book was released on 2000-10-09 with total page 1286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features* The most comprehensive book available on this topic* Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology* Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology* Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Miller's Anesthesia E-Book

Author : Ronald D. Miller
Publisher : Elsevier Health Sciences
ISBN 13 : 0323280110
Total Pages : 4094 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Miller's Anesthesia E-Book by : Ronald D. Miller

Download or read book Miller's Anesthesia E-Book written by Ronald D. Miller and published by Elsevier Health Sciences. This book was released on 2014-10-20 with total page 4094 pages. Available in PDF, EPUB and Kindle. Book excerpt: From fundamental principles to advanced subspecialty procedures, Miller’s Anesthesia covers the full scope of contemporary anesthesia practice. This go-to medical reference book offers masterful guidance on the technical, scientific, and clinical challenges you face each day, in addition to providing the most up-to-date information available for effective board preparation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Address the unique needs of pediatric patients with guidance from an entire section on pediatric anesthesia. View more than 1,500 full-color illustrations for enhanced visual clarity. Access step-by-step instructions for patient management, as well as an in-depth analysis of ancillary responsibilities and problems. Quickly reference important concepts with ‘Key Points’ boxes integrated into every chapter. Stay current on today's most recent anesthetic drugs and guidelines/protocols for anesthetic practice and patient safety, and access expanded coverage on new techniques such as TEE and other monitoring procedures. Take advantage of the unique, international perspectives of prominent anesthesiologists from all over the world, including the UK, Australia, India, Brazil, and Germany. Remain at the forefront of new developments in anesthesia with coverage of hot topics including Non-OR Anesthesia; Role of the Anesthesiologist in Disasters; Sleep Medicine in Anesthesia; Perioperative and Anesthesia-related Neurotoxicity; Anesthetic Implications of Complementary and Alternative Medicine; and Robotics. Study brand-new chapters on Perioperative Fluid Management; Extracorporeal Support Therapies; Anesthesia for Organ Donation/Procurement; and Malignant Hyperthermia and other Genetic Disorders.

Clinical Calculations - E-Book

Author : Joyce LeFever Kee
Publisher : Elsevier Health Sciences
ISBN 13 : 0323674224
Total Pages : 432 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Clinical Calculations - E-Book by : Joyce LeFever Kee

Download or read book Clinical Calculations - E-Book written by Joyce LeFever Kee and published by Elsevier Health Sciences. This book was released on 2020-06-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to calculate drug dosages safely, accurately, and easily with Kee’s Clinical Calculations, 9th Edition! This market-leading text covers all four major drug calculation methods, including ratio & proportion, formula, fractional equation, and dimensional analysis. It also includes practice problems for both general care as well as specialty areas such as pediatrics, labor and delivery, critical care, and community nursing. With its market-leading, comprehensive coverage; strong emphasis on patient safety; and the incorporation of the latest information on antidiabetic agents, anticoagulant agents, drug administration techniques, and devices; Kee remains the winning choice for easy drug calculation mastery. Coverage of all four major drug calculation methods includes ratio & proportion, formula, fractional equation, and dimensional analysis to help you learn and apply the method that works best for you. The latest information on drug administration techniques and devices helps you master the most up-to-date techniques of drug administration, including oral, intravenous, intra-muscular, subcutaneous, and other routes. Caution boxes provide alerts to problems or issues related to various drugs and their administration. Information on infusion pumps covers enteral, single, multi-channel, PCA, and insulin; and explains their use in drug administration. Calculations for Specialty Areas section addresses the drug calculations needed to practice in pediatric, critical care, labor and delivery, and community settings. Detailed, full-color photos and illustrations show the most current equipment for IV therapy, the latest types of pumps, and the newest syringes. Comprehensive post-test lets you test your knowledge of key concepts from the text. NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. NEW! Updated practice problems across the text incorporate the latest drugs and dosages.

Cardioprotection

Author : Derek Hausenloy
Publisher : OUP Oxford
ISBN 13 : 0191575488
Total Pages : 144 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Cardioprotection by : Derek Hausenloy

Download or read book Cardioprotection written by Derek Hausenloy and published by OUP Oxford. This book was released on 2009-08-20 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.

Core Topics in Cardiac Anesthesia

Author : Jonathan H. Mackay
Publisher : Cambridge University Press
ISBN 13 : 9780521196857
Total Pages : 0 pages
Book Rating : 4.1/5 (968 download)

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Book Synopsis Core Topics in Cardiac Anesthesia by : Jonathan H. Mackay

Download or read book Core Topics in Cardiac Anesthesia written by Jonathan H. Mackay and published by Cambridge University Press. This book was released on 2012-03-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists.