Cardioprotection

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Cardioprotection

Author : Derek Hausenloy
Publisher : OUP Oxford
ISBN 13 : 0191575488
Total Pages : 144 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Cardioprotection by : Derek Hausenloy

Download or read book Cardioprotection written by Derek Hausenloy and published by OUP Oxford. This book was released on 2009-08-20 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide with 3.8 million men and 3.4 million women dying each year. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems. This book focuses on the role of cardioprotection in surgery and the use of pharmacological therapies such as ACE-inhibitors, statins and beta-blockers in order to reduce the myocardial injury sustained by the patient and the significant risk of morbidity and mortality. It includes new cardioprotective strategies aimed at improving the clinical outcomes of patients in these settings, as well as current well-established methods for reducing myocardial injury in acute coronary syndrome patients.

Delayed Preconditioning and Adaptive Cardioprotection

Author : G.F. Baxter
Publisher : Springer Science & Business Media
ISBN 13 : 9401153124
Total Pages : 240 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Delayed Preconditioning and Adaptive Cardioprotection by : G.F. Baxter

Download or read book Delayed Preconditioning and Adaptive Cardioprotection written by G.F. Baxter and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the ability of myocardium to adapt to ischaemic stress has continued to grow since the discovery of ischaemic preconditioning in 1986. In 1993, two reports heralded the recognition of a delayed preconditioning response in the heart, now commonly known as the `second window' of protection. Since then, a number of studies have described the ability of delayed preconditioning and related adaptive phenomena to protect against a variety of pathologies in the ischaemic and reperfused myocardium. Our understanding of the cellular mechanisms of sub-acute adaptive cardioprotection has advanced considerably during this period. This compilation of state-of-the-art reviews by those who have made significant contributions to this field provides detailed and critical analysis of this research, from molecular basis to potential clinical relevance. The book aims to provide an authoritative, comprehensive and thoroughly up-to-date overview for scientists and clinicians engaged in, or observing, this rapidly-developing area of heart research. It will also be of interest to those engaged in research on other tissues where ischaemia-reperfusion pathology is of major concern.

Cardioprotection, Sex and Gender Differences

Author : Claudia Penna
Publisher : Frontiers Media SA
ISBN 13 : 2832502075
Total Pages : 111 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Cardioprotection, Sex and Gender Differences by : Claudia Penna

Download or read book Cardioprotection, Sex and Gender Differences written by Claudia Penna and published by Frontiers Media SA. This book was released on 2022-10-11 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cardioprotection Against Acute Myocardial Infarction

Author : Shinya Minatoguchi
Publisher : Springer Nature
ISBN 13 : 981150167X
Total Pages : 64 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Cardioprotection Against Acute Myocardial Infarction by : Shinya Minatoguchi

Download or read book Cardioprotection Against Acute Myocardial Infarction written by Shinya Minatoguchi and published by Springer Nature. This book was released on 2019-11-16 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide readers with a detailed understanding of the ischemic damage to the myocardium after myocardial infarction, as well as essential tools for the treatment of damaged heart after myocardial infarction. It discusses various methods such as pharmacological pre- and post-conditioning, cytokine therapy, and cell therapy especially using Muse cells.The coverage of Muse cell therapy, which includes the latest work done by the author and his collaborators, is a unique feature of the book. Muse cells have self-renewability and have ability to differentiate into cells with the characteristics of all three germ layers from a single cell, while they are non-tumorigenic. It is the first book to feature the Muse cell therapy, which may offer the new promising therapeutic strategy for acute myocardial infarction.

Adenosine, Cardioprotection and Its Clinical Application

Author : Robert M. Mentzer Jr.
Publisher : Springer Science & Business Media
ISBN 13 : 1441987363
Total Pages : 239 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Adenosine, Cardioprotection and Its Clinical Application by : Robert M. Mentzer Jr.

Download or read book Adenosine, Cardioprotection and Its Clinical Application written by Robert M. Mentzer Jr. and published by Springer Science & Business Media. This book was released on 2012-09-10 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immense growth in the number of articles on adenosine cardioprotection in recent years has been related in large part to the hypothesis that adenosine plays a role in ischemic preconditioning. Ischemic preconditioning is the phenomenon in which a brief period of ischemia (and reperfusion) prior to a more prolonged occlusion reduces myocardial infarct size. This form of myocardial protection has received much interest because ischemic preconditioning has been shown to be the most potent means of reducing infarct size in all animal models so far tested. Within the last six years, the principal focus of adenosine cardioprotection research has centered on the role of adenosine receptors. It is currently thought that adenosine protects the ischemic heart primarily via the activation of adenosine A1 receptors located on the cardiac myocytes. Adenosine is used clinically for terminating supraventricular tachycardia, and as a diagnostic tool in coronary imaging, and has been used postoperatively for blood pressure control after heart surgery. There are also recent reports that adenosine may be safely tolerated and a potentially beneficial additive to cardioplegic solutions during open heart surgery in humans. There is even evidence that ischemic preconditioning may occur in humans under various clinical situations. This volume contains chapters from contributors to the first three symposia on 'Adenosine, Cardioprotection, and its Clinical Application'. All aspects of adenosine cardioprotection and ischemic preconditioning, including potential mechanisms and clinical applications, are discussed by experts in these areas. The reader will find this book to be an excellent source of information on these topics, as well as a guide to future experiments.

Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection

Author : Naseer Ahmed
Publisher : Academic Press
ISBN 13 : 0128182539
Total Pages : 140 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection by : Naseer Ahmed

Download or read book Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection written by Naseer Ahmed and published by Academic Press. This book was released on 2019-05-30 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection. Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection. Provides detailed and critical analysis of the latest research in the field from molecular basis to potential clinical relevance Examines the effect of fingolimod/sphingosine 1-phosphate in cardioprotection, pointing to future myocardial preventative strategies

Cardiovascular Toxicity Associated with Cancer Treatment: Strategies for Diagnosis, Management and Cardioprotection

Author : Zhi-Ren Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832508006
Total Pages : 225 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Cardiovascular Toxicity Associated with Cancer Treatment: Strategies for Diagnosis, Management and Cardioprotection by : Zhi-Ren Zhang

Download or read book Cardiovascular Toxicity Associated with Cancer Treatment: Strategies for Diagnosis, Management and Cardioprotection written by Zhi-Ren Zhang and published by Frontiers Media SA. This book was released on 2022-11-30 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The ESC Textbook of Preventive Cardiology

Author : Stephan Gielen
Publisher : European Society of Cardiology
ISBN 13 : 0199656657
Total Pages : 369 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis The ESC Textbook of Preventive Cardiology by : Stephan Gielen

Download or read book The ESC Textbook of Preventive Cardiology written by Stephan Gielen and published by European Society of Cardiology. This book was released on 2015 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: "EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."

Mitochondrial Biology and Experimental Therapeutics

Author : Paulo J. Oliveira
Publisher : Springer
ISBN 13 : 3319733443
Total Pages : 708 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Mitochondrial Biology and Experimental Therapeutics by : Paulo J. Oliveira

Download or read book Mitochondrial Biology and Experimental Therapeutics written by Paulo J. Oliveira and published by Springer. This book was released on 2018-03-21 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.

Cardioprotection

Author : Derek Hausenloy
Publisher : Oxford University Press
ISBN 13 : 019954476X
Total Pages : 138 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Cardioprotection by : Derek Hausenloy

Download or read book Cardioprotection written by Derek Hausenloy and published by Oxford University Press. This book was released on 2009-08-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease (CHD) is the leading cause of death worldwide. Cardioprotection refers to the prevention of CHD and the clinical improvement in patients suffering from cardiovascular problems.

Cardio-Protection and Heart Repair: New Drugs, Targets and Approaches

Author : Benzhi Cai
Publisher : Frontiers Media SA
ISBN 13 : 2889740900
Total Pages : 727 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Cardio-Protection and Heart Repair: New Drugs, Targets and Approaches by : Benzhi Cai

Download or read book Cardio-Protection and Heart Repair: New Drugs, Targets and Approaches written by Benzhi Cai and published by Frontiers Media SA. This book was released on 2022-01-19 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Myocardial Protection

Author : Tomas A. Salerno
Publisher : John Wiley & Sons
ISBN 13 : 1405178434
Total Pages : 344 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Myocardial Protection by : Tomas A. Salerno

Download or read book Myocardial Protection written by Tomas A. Salerno and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Molecules to Medicine with mTOR

Author : Kenneth Maiese
Publisher : Academic Press
ISBN 13 : 012802755X
Total Pages : 472 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecules to Medicine with mTOR by : Kenneth Maiese

Download or read book Molecules to Medicine with mTOR written by Kenneth Maiese and published by Academic Press. This book was released on 2016-02-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin. Covers the role of mTOR by internationally recognized expert contributors in the field. Provides a clear picture of the complexity of mTOR signaling as well as of the different approaches that could target this pathway at various levels. Includes analysis of the role of mTOR and in both health and disease. Serves as an important resource for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings.

Pharmacological Approaches to Cardioprotection

Author : James Allen Coles
Publisher :
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Pharmacological Approaches to Cardioprotection by : James Allen Coles

Download or read book Pharmacological Approaches to Cardioprotection written by James Allen Coles and published by . This book was released on 2002 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novel Interventions for Cardioprotection

Author : Dale Adam Lauver
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Novel Interventions for Cardioprotection by : Dale Adam Lauver

Download or read book Novel Interventions for Cardioprotection written by Dale Adam Lauver and published by . This book was released on 2007 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proteomic and Genomic Analysis of Cardiovascular Disease

Author : Jennifer E. Van Eyk
Publisher : John Wiley & Sons
ISBN 13 : 3527605452
Total Pages : 423 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Proteomic and Genomic Analysis of Cardiovascular Disease by : Jennifer E. Van Eyk

Download or read book Proteomic and Genomic Analysis of Cardiovascular Disease written by Jennifer E. Van Eyk and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.

Oxidative Stress in Heart Diseases

Author : Sajal Chakraborti
Publisher : Springer Nature
ISBN 13 : 9811382735
Total Pages : 596 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Oxidative Stress in Heart Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.