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Muscles As Molecular And Metabolic Machines
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Book Synopsis Muscles as Molecular and Metabolic Machines by : Peter W. Hochachka
Download or read book Muscles as Molecular and Metabolic Machines written by Peter W. Hochachka and published by CRC Press. This book was released on 2019-06-04 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1994, this book explores the paradigm of muscles as molecular and metabolic machines in which all structures and functions are exquisitely integrated and matched to each other. The analysis begins with a standard reductionist approach-reviewing the integrated machine parts. The key working components of the complete muscle machine are proteins (soluble, organelle, or membrane localized), and a conservative count indicates that today more than 100 such machine parts are known, essentially all occurring as cell specific isoforms. Random assortment of these machine parts or protein isoforms could generate an astronomical number of "muscle machines" and an equally enormous number of muscle fiber types. The question is, why aren't such large numbers ever seen? To attack this problem, the reductionist approach is complemented with an integrationist/adaptational one. Evidence is presented that the more highly specialized the muscle type, the further one moves from the above extreme; in the most highly specialized muscles, typically only one fiber type is found. It is argued that instead of random assortment of isoforms or machine parts, only specific and often unique combinations can work in appropriate fashion. A few established examples of this fundamental principle are reviewed, but emphasis is placed on the fact that we know dreadfully little about why this is so and what kinds of further studies are needed. The issue of why the very large numbers of fiber types theoretically possible are never even approximately realized has never before been addressed. Indeed, it is rarely recognized. Muscles as Molecular and Metabolic Machines is the first work of its kind on the subject.
Book Synopsis Muscles as Molecular and Metabolic Machines by :
Download or read book Muscles as Molecular and Metabolic Machines written by and published by . This book was released on 2009 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Muscle Metabolism by : Juleen R Zierath
Download or read book Muscle Metabolism written by Juleen R Zierath and published by CRC Press. This book was released on 2002-02-28 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention hav
Book Synopsis Genetics and Molecular Biology of Muscle Adaptation by : Neil Spurway
Download or read book Genetics and Molecular Biology of Muscle Adaptation written by Neil Spurway and published by Elsevier Health Sciences. This book was released on 2006-01-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title is directed primarily towards health care professionals outside of the United States. It starts with the origin of life and ends with the mechanisms that make muscles adapt to different forms of training. In between, it considers how evidence has been obtained about the extent of genetic influence on human capacities, how muscles and their fibres are studied for general properties and individual differences, and how molecular biological techniques have been combined with physiological ones to produce the new discipline of molecular exercise physiology. This is the first book on such topics written specifically for modules in exercise and sport science at final year Hons BSc and taught MSc levels.
Book Synopsis The Role of Protein and Amino Acids in Sustaining and Enhancing Performance by : Institute of Medicine
Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Book Synopsis Muscles & Molecules by : Gerald H. Pollack
Download or read book Muscles & Molecules written by Gerald H. Pollack and published by Ebner and Sons Publishers. This book was released on 1990 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: An award-winning book that topples the widely accepted edifice of understanding on how muscles contract, replacing it with a simpler construct that better fits the evidence. This is a beautifully produced, single-authored text by one of our more thoughtful, if unconventional, authorities on the mechanism of muscular contraction. Clearly and elegantly written, and with a charm and grace not often seen in modern scientific writing.
Book Synopsis Machina Carnis by : Dorothy M. Needham
Download or read book Machina Carnis written by Dorothy M. Needham and published by Cambridge University Press. This book was released on 1971-11-30 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work.
Book Synopsis Noninvasive Evaluation of Metabolic Capacities in Human Skeletal Muscles by : Glenn A. Walter
Download or read book Noninvasive Evaluation of Metabolic Capacities in Human Skeletal Muscles written by Glenn A. Walter and published by . This book was released on 1997 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Muscle Metabolism During Exercise by : Bengt Pernow
Download or read book Muscle Metabolism During Exercise written by Bengt Pernow and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Exercise Metabolism by : Mark Hargreaves
Download or read book Exercise Metabolism written by Mark Hargreaves and published by Human Kinetics. This book was released on 2006 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for biochemists, sport nutritionists, exercise physiologists, and graduate students in those disciplines. Provides information on the metabolic processes that take place during exercise, examining in depth the mobilization and utilization of substrates during physical activity. Focuses primarily on the skeletal muscle, but also discusses the roles of the liver and adipose tissue. Annotation copyright by Book News, Inc., Portland, OR
Book Synopsis Biochemical Adaptation by : Peter William Hochachka
Download or read book Biochemical Adaptation written by Peter William Hochachka and published by Oxford University Press, USA. This book was released on 2002 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Suitable for graduates and undergraduates in environmental biology, comparative physiology, and marine biology, this text lays out the principles of mechanistic comparative physiology in an ecological and evolutionary context. This text lays out the principles of mechanistic comparative physiology in an ecological and evolutionary context. The subject of evolutionary physiology has been advancing considerably and this book will bring readers up to date on a number of new techniques, ideas and data. Topics include NMR spectroscopy and molecular biology, evolution and adaptation, phylogenetically-based analytical techniques and more.
Author :Ana Cláudia Garcia De Oliveira Duarte Publisher :Frontiers Media SA ISBN 13 :2832509878 Total Pages :165 pages Book Rating :4.8/5 (325 download)
Book Synopsis Adipose tissue and skeletal muscle as endocrine organs: role of cytokines in health and disease by : Ana Cláudia Garcia De Oliveira Duarte
Download or read book Adipose tissue and skeletal muscle as endocrine organs: role of cytokines in health and disease written by Ana Cláudia Garcia De Oliveira Duarte and published by Frontiers Media SA. This book was released on 2022-12-29 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles of Human Locomotion by : Thomas Rowland
Download or read book Principles of Human Locomotion written by Thomas Rowland and published by Cambridge Scholars Publishing. This book was released on 2020-09-10 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses how the general principles of biology influence the human capacity for locomotion, and, conversely, how understanding the nature of muscular activity might provide insights into the basic nature of living beings. Through a series of essays, the book relates the evolutionary basis of animal locomotion to recognizing the determinants of exercise capacity. While raising more questions than providing answers, the discussions will assume that without knowing the correct questions to ask, the answers will not be forthcoming. At the root of this book lies the central query: what is it that separates the principles governing the function of living beings from those that dictate the inanimate world? The discussions here address this issue from the expectation that clues to the answer can be obtained through understanding adaptations to the stresses imposed by physical exercise. As such, the book provides thought-provoking analyses of the biological basis of locomotion that will stimulate future efforts to understand these phenomena.
Book Synopsis Technological and Medical Implications of Metabolic Control Analysis by : Athel Cornish-Bowden
Download or read book Technological and Medical Implications of Metabolic Control Analysis written by Athel Cornish-Bowden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril.
Download or read book Creatine written by Melvin H. Williams and published by Human Kinetics. This book was released on 1999 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, scientific look at creatine--the supplement of choice for today's serious athletes and fitness enthusiasts--what it is, how it works, how to use it, and what it can do for an athlete. 19 photos.
Book Synopsis Environmental Stressors and Gene Responses by : J.M. Storey
Download or read book Environmental Stressors and Gene Responses written by J.M. Storey and published by Elsevier. This book was released on 2000-07-31 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell and Molecular Responses to Stress is a new multi-volume book series from Elsevier Science that focuses on how organisms respond at a molecular level to environmental stresses imposed upon them. All organisms deal with variations in multiple environmental factors including temperature, oxygen, salinity, and water availability. Many show amazing tolerances to extreme stress with remarkable biochemical adaptations that allow life to persist under very difficult circumstances. This series explores the molecular mechanisms by which cells and organisms respond to stress, focusing on the variations in metabolic response that allow some cells and organisms to deal with extreme stress, others to endure stress within strict limits, and others to have a very low tolerance for changes in environmental parameters.Articles from within the series highlight the elastic limits of molecular responses in Nature, with examples drawn from animal, plant and bacteria systems.Volume 1, begins by considering some of the roles of environmental stress in determining the geographic distribution of animals and in promoting species divergence and then explores gene expression and metabolic responses to environmental stress with examples of adaptation to high and low temperature, osmotic, anoxia/ischemia, desiccation, high pressure and heavy metal stresses.