Multivalency

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Multivalency

Author : Jurriaan Huskens
Publisher : John Wiley & Sons
ISBN 13 : 1119143462
Total Pages : 434 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Multivalency by : Jurriaan Huskens

Download or read book Multivalency written by Jurriaan Huskens and published by John Wiley & Sons. This book was released on 2018-02-05 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.

Fragment-based Approaches in Drug Discovery

Author : Wolfgang Jahnke
Publisher : John Wiley & Sons
ISBN 13 : 3527608605
Total Pages : 391 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Fragment-based Approaches in Drug Discovery by : Wolfgang Jahnke

Download or read book Fragment-based Approaches in Drug Discovery written by Wolfgang Jahnke and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.

Glycoscience

Author : Bertram O. Fraser-Reid
Publisher : Springer Science & Business Media
ISBN 13 : 3540361545
Total Pages : 2847 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Glycoscience by : Bertram O. Fraser-Reid

Download or read book Glycoscience written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2008-04-14 with total page 2847 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.

Washing the Brain

Author : Andrew Goatly
Publisher : John Benjamins Publishing
ISBN 13 : 9789027227133
Total Pages : 464 pages
Book Rating : 4.2/5 (271 download)

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Book Synopsis Washing the Brain by : Andrew Goatly

Download or read book Washing the Brain written by Andrew Goatly and published by John Benjamins Publishing. This book was released on 2007-01-01 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary metaphor theory has recently begun to address the relation between metaphor, culture and ideology. In this wide-ranging book, Andrew Goatly, using lexical data from his database Metalude, investigates how conceptual metaphor themes construct our thinking and social behaviour in fields as diverse as architecture, engineering, education, genetics, ecology, economics, politics, industrial time-management, medicine, immigration, race, and sex. He argues that metaphor themes are created not only through the universal body but also through cultural experience, so that an apparently universal metaphor such as event-structure as realized in English grammar is, in fact, culturally relative, compared with e.g. the construal of 'cause and effect' in the Algonquin language Blackfoot. Moreover, event-structure as a model is both scientifically reactionary and, as the basis for technological mega-projects, has proved environmentally harmful. Furthermore, the ideologies of early capitalism created or exploited a selection of metaphor themes historically traceable through Hobbes, Hume, Smith, Malthus and Darwin. These metaphorical concepts support neo-Darwinian and neo-conservative ideologies apparent at the beginning of the 21st century, ideologies underpinning our social and environmental crises. The conclusion therefore recommends skepticism of metaphor's reductionist tendencies.

Handbook of Nanofabrication

Author :
Publisher : Academic Press
ISBN 13 : 9780123751775
Total Pages : 310 pages
Book Rating : 4.7/5 (517 download)

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Book Synopsis Handbook of Nanofabrication by :

Download or read book Handbook of Nanofabrication written by and published by Academic Press. This book was released on 2010-05-25 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the devices and systems used in modern industry are becoming progressively smaller and have reached the nanoscale domain. Nanofabrication aims at building nanoscale structures, which can act as components, devices, or systems, in large quantities at potentially low cost. Nanofabrication is vital to all nanotechnology fields, especially for the realization of nanotechnology that involves the traditional areas across engineering and science. Includes chapters covering the most important Nanofabrication techniques, which aids comprehensive understanding of the latest manufacturing technologies encountered in the field of nano-level manufacturing which is essential for preparing for advanced study and application in nanofabrication techniques by enabling thorough understanding of the entire nanofabrication process as it applies to advanced electronic and related manufacturing technologies. Each chapter covers a nanofabrication technique comprehensively, which allows the reader to learn to produce nanometer-level products as well as collect, process, and analyze data, improve process parameters, and how to assist engineers in research, development and manufacture of the same. Includes contributions from recognized experts from around the globe, making the reader aware of variations in similar techniques applied in different geographical locations and is better positioned to establish all possible global applications.

Synthetic Receptors for Biomolecules

Author : Bradley D. Smith
Publisher : Royal Society of Chemistry
ISBN 13 : 1849739714
Total Pages : 466 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Synthetic Receptors for Biomolecules by : Bradley D. Smith

Download or read book Synthetic Receptors for Biomolecules written by Bradley D. Smith and published by Royal Society of Chemistry. This book was released on 2015-07-10 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic receptor molecules, molecules that mimic antibody recognition, are widely used for developing drug leads; drug delivery vehicles; imaging agents; sensing agents; capture agents and separation systems. Synthetic Receptors for Biomolecules covers the most effective synthetic receptors for each major class of biomolecules within the context of specific applications. The book starts with an introduction to the applications of synthetic receptors for biomolecules and their design and synthesis for biomolecule recognition. Dedicated chapters then cover synthetic receptors for the key biomolecules including inorganic cations; small organic and inorganic anions; carbohydrates; nucleosides/nucleotides; oligonucleotides; amino acids and peptides; protein surfaces as well as non-polar and polar lipids; Each chapter follows the same systematic format of (a) chemical structures and physical properties of the biomolecule, (b) biological recognition of the biomolecule, (c) synthetic receptors for the biomolecule, (d) future directions and challenges. Edited by a leader in the field, the book is written in an accessible style for readers new to supramolecular chemistry or for those looking for synthetic receptors.

Carbohydrate-based Drug Discovery, 2 Volume Set

Author : Chi-Huey Wong
Publisher : John Wiley & Sons
ISBN 13 : 9783527306329
Total Pages : 520 pages
Book Rating : 4.3/5 (63 download)

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Book Synopsis Carbohydrate-based Drug Discovery, 2 Volume Set by : Chi-Huey Wong

Download or read book Carbohydrate-based Drug Discovery, 2 Volume Set written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2003-10-17 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > Chemical Synthesis of Carbohydrates > Carbohydrate Biosynthesis and Metabolism > Carbohydrate Analysis > Cellular Functions of Carbohydrates > Development of Carbohydrate-based Drugs A premier resource for carbohydrate chemists and drug developers, this comprehensive two-volume work contains contributions by more than 50 of the world's leading carbohydrate chemists.

Essentials of Carbohydrate Chemistry and Biochemistry

Author : Thisbe K. Lindhorst
Publisher : John Wiley & Sons
ISBN 13 : 3527315284
Total Pages : 333 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Essentials of Carbohydrate Chemistry and Biochemistry by : Thisbe K. Lindhorst

Download or read book Essentials of Carbohydrate Chemistry and Biochemistry written by Thisbe K. Lindhorst and published by John Wiley & Sons. This book was released on 2007-04-09 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise yet complete, this is a succinct introduction to the topic, covering both basic chemistry as well as such advanced topics as high-throughput analytics and glycomics -- in one handy volume. This improved and expanded 3rd edition features all-new material on combinatorial synthesis of carbohydrates and carbohydrate biodiversity, and each chapter now contains study questions for self-learning and classroom teaching. Didactically written by an experienced lecturer and graduate student advisor, the text is backed by practical examples and more than 150 study questions tailored to students' needs.

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Analytical Methods in Supramolecular Chemistry

Author : Christoph A. Schalley
Publisher : John Wiley & Sons
ISBN 13 : 3527644148
Total Pages : 849 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Analytical Methods in Supramolecular Chemistry by : Christoph A. Schalley

Download or read book Analytical Methods in Supramolecular Chemistry written by Christoph A. Schalley and published by John Wiley & Sons. This book was released on 2012-09-25 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of "Analytical Methods in Supramolecular Chemistry" comes in two volumes and covers a broad range of modern methods and techniques now used for investigating supramolecular systems, e. g. NMR spectroscopy, mass spectrometry, extraction methods, crystallography, single molecule spectroscopy, electrochemisty, and many more. In this second edition, tutorial inserts have been introduced, making the book also suitable as supplementary reading for courses on supramolecular chemistry. All chapters have been revised and updated and four new chapters have been added. A must-have handbook for Organic and Analytical Chemists, Spectroscopists, Materials Scientists, and Ph.D. Students in Chemistry. From reviews of the first edition: "This timely book should have its place in laboratories dealing with supramolecular objects. It will be a source of reference for graduate students and more experienced researchers and could induce new ideas on the use of techniques other than those usually used in the laboratory." Journal of the American Chemical Society (2008) VOL. 130, NO. 1 doi: 10.1021/ja0769649 "The book as a whole or single chapters will stimulate the reader to widen his horizon in chemistry and will help him to have new ideas in his research." Anal Bioanal Chem (2007) 389:2039-2040 DOI: 10.1007/s00216-007-1677-1

Molecular Aspects of Host-Pathogen Interactions

Author : Society for General Microbiology. Symposium
Publisher : Cambridge University Press
ISBN 13 : 9780521592154
Total Pages : 378 pages
Book Rating : 4.5/5 (921 download)

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Book Synopsis Molecular Aspects of Host-Pathogen Interactions by : Society for General Microbiology. Symposium

Download or read book Molecular Aspects of Host-Pathogen Interactions written by Society for General Microbiology. Symposium and published by Cambridge University Press. This book was released on 1997-05-13 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reports the latest advances in defining the molecular basis of infection in both bacterial and viral systems.

Host-Guest Chemistry

Author : Soledad Penades
Publisher : Springer
ISBN 13 : 3540450106
Total Pages : 241 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Host-Guest Chemistry by : Soledad Penades

Download or read book Host-Guest Chemistry written by Soledad Penades and published by Springer. This book was released on 2003-07-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts

Synthesis and Biological Applications of Glycoconjugates

Author : Olivier Renaudet
Publisher : Bentham Science Publishers
ISBN 13 : 160805277X
Total Pages : 283 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Synthesis and Biological Applications of Glycoconjugates by : Olivier Renaudet

Download or read book Synthesis and Biological Applications of Glycoconjugates written by Olivier Renaudet and published by Bentham Science Publishers. This book was released on 2011 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological processes over several decades. The recent emergence of glycomics has strengthened this interest and notably contributed t

Carbohydrate Recognition

Author : Binghe Wang
Publisher : John Wiley & Sons
ISBN 13 : 0470592079
Total Pages : 448 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Carbohydrate Recognition by : Binghe Wang

Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.

The Investigations of Sherlock Holmes

Author : John Heywood
Publisher : Andrews UK Limited
ISBN 13 : 1780926081
Total Pages : 165 pages
Book Rating : 4.7/5 (89 download)

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Book Synopsis The Investigations of Sherlock Holmes by : John Heywood

Download or read book The Investigations of Sherlock Holmes written by John Heywood and published by Andrews UK Limited. This book was released on 2014-06-18 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over a century since Sherlock Holmes made his first appearance, and readers throughout the world still clamour for more of his exciting adventures. We are happy to announce that seven stories from the despatch-box of John Watson, M.D. have recently come to light. In them you will meet such characters as the Reverend Nathaniel Flowerdew, vicar of Great Mowl; Professor Hendricks and his aquarium; the Right Honourable Robert Bonnington Smythe, once expected to become Premier of England; and the man in the red flannel waistcoat who was at both ends of the street at the same time. 'My mind is like a racing engine, tearing itself to pieces because it is not connected up with the work for which it was built,' Holmes said of himself in his darker moments. In these stories the engine is fully engaged and at full throttle as Holmes brings all his daring and intelligence to bear on the puzzle of the Quiet Crescent, the case of the Apprentice's Notebook, and other mysteries in this collection.

Everyday Ideas

Author : Ronald J. Zboray
Publisher : Univ. of Tennessee Press
ISBN 13 : 9781572334717
Total Pages : 470 pages
Book Rating : 4.3/5 (347 download)

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Book Synopsis Everyday Ideas by : Ronald J. Zboray

Download or read book Everyday Ideas written by Ronald J. Zboray and published by Univ. of Tennessee Press. This book was released on 2006 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyday Ideas: Socioliterary Experience among Antebellum New Englanders takes an unprecedented look at the use of literature in everyday life in one of history's most literate societies-the home ground of the American Renaissance. Using information pulled from four thousand manuscript letters and diaries, Everyday Ideas provides a comprehensive picture of how the social and literary dimensions of human existence related in antebellum New England. Penned by ordinary people-factory workers, farmers, clerks, storekeepers, domestics, and teachers and other professionals-the writings examined here brim with thoughtful references to published texts, lectures, and speeches by the period's canonized authors and lesser lights. These personal accounts also give an insider's perspective on issues ranging from economic problems, to social status conflicts, to being separated from loved ones by region, state, or nation. Everyday Ideas examines such references and accounts and interprets the multiple ways literature figured into the lives of these New Englanders. An important aid in understanding historical readers and social authorship practices, Everyday Ideas is a unique resource on New England and provides a framework for understanding the profound role of ideas in the everyday world of the antebellum period.

Organic Nanochemistry

Author : Yuming Zhao
Publisher : John Wiley & Sons
ISBN 13 : 111887045X
Total Pages : 292 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Organic Nanochemistry by : Yuming Zhao

Download or read book Organic Nanochemistry written by Yuming Zhao and published by John Wiley & Sons. This book was released on 2024-01-18 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: ORGANIC NANOCHEMISTRY How-to guide for entry-level practitioners to quickly learn the cutting-edge research concepts and methodologies of modern organic nanochemistry Organic Nanochemistry describes the fundamentals of organic nanochemistry research, encompassing modern synthetic reactions, supramolecular strategies, nanostructure and property characterization techniques, and state-of-the-art data analysis and processing methods, along with synthetic chemistry as applied to organic nanomaterials and molecular devices. Accompanying each of these principles are case studies (from basic design to detailed experimental implementation) to help the reader fully comprehend the concepts and methods involved. Various theories suitable for nanoscale simulations, including quantum mechanics, semi-empirical quantum mechanics, and molecular dynamics theories, are discussed at an introductory level. Computational examples are provided, allowing interested readers to grasp essential modelling techniques for better understanding of organic nanochemistry. The content is paired with online supplementary material that includes instructional materials and guides to using common scientific software for computational modelling and simulations. Written by a highly qualified professor, Organic Nanochemistry includes discussion on: Key concepts and theories of organic chemistry, which are essential to understand the fundamental properties of organic molecular and supramolecular systems Useful synthetic methodologies for the synthesis and functionalization of organic nanomaterials, and the chemistry and application of exotic carbon nanomaterials Supramolecular aspects in organic nanochemistry, especially the well-developed disciplines of host-guest chemistry and organic self-assembly chemistry Construction and testing of molecular devices and molecular machines and state-of-the-art computational modelling methods for properties of nanoscale organic systems Guiding the reader on a journey from familiar chemical concepts and principles to cutting-edge research of nano-science and technology, Organic Nanochemistry serves as an excellent textbook learning resource for advanced and graduate students, as well as a self-study guide or how-to reference for practicing chemists.