Multiscale Modeling Of Vascular Dynamics Of Micro And Nano Particles

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Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles

Author : Huilin Ye
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643277928
Total Pages : 112 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles by : Huilin Ye

Download or read book Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles written by Huilin Ye and published by Morgan & Claypool Publishers. This book was released on 2020-01-02 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles

Author : Huilin Ye
Publisher :
ISBN 13 : 9780750330190
Total Pages : 0 pages
Book Rating : 4.3/5 (31 download)

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Book Synopsis Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles by : Huilin Ye

Download or read book Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles written by Huilin Ye and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiscale Modeling of Particle Interactions

Author : Michael King
Publisher : John Wiley & Sons
ISBN 13 : 047057982X
Total Pages : 398 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Multiscale Modeling of Particle Interactions by : Michael King

Download or read book Multiscale Modeling of Particle Interactions written by Michael King and published by John Wiley & Sons. This book was released on 2010-03-30 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.

Multiscale Modeling of Particle Interactions

Author : Michael King
Publisher : Wiley
ISBN 13 : 9780470242353
Total Pages : 388 pages
Book Rating : 4.2/5 (423 download)

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Book Synopsis Multiscale Modeling of Particle Interactions by : Michael King

Download or read book Multiscale Modeling of Particle Interactions written by Michael King and published by Wiley. This book was released on 2010-03-22 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover how the latest computational tools are building our understanding of particle interactions and leading to new applications With this book as their guide, readers will gain a new appreciation of the critical role that particle interactions play in advancing research and developing new applications in the biological sciences, chemical engineering, toxicology, medicine, and manufacturing technology The book explores particles ranging in size from cations to whole cells to tissues and processed materials. A focus on recreating complex, real-world dynamical systems helps readers gain a deeper understanding of cell and tissue mechanics, theoretical aspects of multiscale modeling, and the latest applications in biology and nanotechnology. Following an introductory chapter, Multiscale Modeling of Particle Interactions is divided into two parts: Part I, Applications in Nanotechnology, covers: Multiscale modeling of nanoscale aggregation phenomena: applications in semiconductor materials processing Multiscale modeling of rare events in self-assembled systems Continuum description of atomic sheets Coulombic dragging and mechanical propelling of molecules in nanofluidic systems Molecular dynamics modeling of nanodroplets and nanoparticles Modeling the interactions between compliant microcapsules and patterned surfaces Part II, Applications in Biology, covers: Coarse-grained and multiscale simulations of lipid bilayers Stochastic approach to biochemical kinetics In silico modeling of angiogenesis at multiple scales Large-scale simulation of blood flow in microvessels Molecular to multicellular deformation during adhesion of immune cells under flow Each article was contributed by one or more leading experts and pioneers in the field. All readers, from chemists and biologists to engineers and students, will gain new insights into how the latest tools in computational science can improve our understanding of particle interactions and support the development of novel applications across the broad spectrum of disciplines in biology and nanotechnology.

Multiscale Modeling of Dynamic Particle Systems

Author : Brendon Waters
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (137 download)

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Book Synopsis Multiscale Modeling of Dynamic Particle Systems by : Brendon Waters

Download or read book Multiscale Modeling of Dynamic Particle Systems written by Brendon Waters and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modeling the dynamics of interacting many-particle systems is one of the central challenges at the forefront of condensed matter physics. When systems of interacting particles are driven out of equilibrium, complex emergent behaviors can arise that are difficult to predict from their individual properties. In this work, we model two such dynamic many-particle systems. The first is a nanocomposite of conductive CrO2and insulating Cr2O3 nanoparticles. We numerically model the nanoparticles as hard spherocylinders, systems of which are compressed into dense, disordered, packings via the mechanical contraction method, with various volume fractions of conductive CrO2. We then analyze the resulting ensembles of these nanocomposites to identify their critical percolation properties through a finite size scaling analysis. We use a randomly walking "blind ant" approach to calculate the conductivity of the nanocomposite and obtain the conductivity critical exponent of the nanocomposite system, which agrees with experimental measurements. Intriguingly, the calculated percolation threshold we obtained,pc= 0.312±0.002, is near (within numerical errors) those found previously in two other systems, disordered jammed spheres, and simple cubic lattice.The second type of system we model the evolution of is embedded grains in two dimensional (2D) crystals. We model 2D materials with the phase field crystal (PFC) model,which captures both atomic spatial resolution and slow diffusive dynamics, allowing for precise mapping of defect structures around evolving grain boundaries. We apply the Cahn-Taylor formulation of grain boundary motion to show that the normal motion of a shrinking embedded grain boundary couples to the tangential motion of atoms along the boundary,resulting in a net rotation of the grain as it changes size. Furthermore, we show that a more complex two component system such as hexagonal boron nitride (h-BN) exhibits a dual mode behavior of grain rotation, where the bonding energy difference between different atomic species results in competing rotations in opposite directions for binary embedded grains. This highlights the role played by the lattice inversion symmetry breaking in binary or multi-component materials as compared to single-component materials. The potential implications for processing techniques used to produce large crystals of 2D materials are also discussed.

A New Multiscale Approach for Dynamic Modeling and Simulation of Micro-nano Biomolecular Systems Characterized by a Low Reynolds Number

Download A New Multiscale Approach for Dynamic Modeling and Simulation of Micro-nano Biomolecular Systems Characterized by a Low Reynolds Number PDF Online Free

Author : Mahdi Hagheshenas-Jaryani
Publisher :
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.:/5 (892 download)

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Book Synopsis A New Multiscale Approach for Dynamic Modeling and Simulation of Micro-nano Biomolecular Systems Characterized by a Low Reynolds Number by : Mahdi Hagheshenas-Jaryani

Download or read book A New Multiscale Approach for Dynamic Modeling and Simulation of Micro-nano Biomolecular Systems Characterized by a Low Reynolds Number written by Mahdi Hagheshenas-Jaryani and published by . This book was released on 2014 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this dissertation, a new multiscale computational framework was developed in order to model and simulate motility of micro-nano-sized objects in fluid environments, characterized with a low Reynolds number. Especially, it has been used for studying the dynamic behavior of biomolecular systems such as motor proteins inside cells. Long simulation run time is one of the most important issues in modeling of cellular and biomolecular systems at the nanoscale due to the multiple time and length scales involved in the dynamics of these systems. These multiscale features are caused by either structure-structure (e.g. flexibility in biological structure or contact) or structure-fluid interactions (e.g. biological structure and surrounding fluid environment) which appear as disproportionality between physical parameters involved in their dynamics. In order to address this issue, the mostly used models, based on the famous overdamped Langevin equation, omit inertial properties in the equations of motion; that leads to a first order model which is inconsistent with the Newton's second law. However, a new dynamic multiscale approach was proposed that uses the concept of the method of multiple scales (MMS) and brings all terms of the equations of motion into proportion with each other that helps to retain the inertia terms. This holds consistency of the model with the governing physical laws, Newton's second law, and experimental observations. In addition, numerical integration's step-size can be increased from commonly used sub-femto seconds to sub-milli seconds. Therefore, simulation run time is reduced significantly in compared with other approaches. The proposed approach was examined in different cases including the dynamics of small objects (microbeads) in an optical trapping process, and locomotion of motor proteins likes myosin V and kinesin-1 in cells. The experimental observations, obtained from the study of trapped small beads in optical tweezers, verify the new multiscale model and show the proposed model can correctly predict the physical characteristics at the nanoscale. In addition, the simulation run-time using the proposed multiscale models was significantly reduced in compared with the original and the first order models. Then, the multiscale model was used for modeling and simulation of motor proteins. The simulation results obtained by the proposed multiscale model show a dynamic behavior of myosin V and kinesin which is more consistent with experimental observations in compared with other overdamped models. In this dissertation, a new online constraint embedding method was invoked in order to facilitate numerical simulation of motor proteins mechanical model, as a multibody system, with on-fly constraints including, 1) holonomic constraints due to use of Euler parameters for describing configuration of proteins and 2) non-holonomic constraints because of contact-impact between proteins and the substrates.

Nano and Cell Mechanics

Author : Horacio D. Espinosa
Publisher : John Wiley & Sons
ISBN 13 : 111848259X
Total Pages : 519 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Nano and Cell Mechanics by : Horacio D. Espinosa

Download or read book Nano and Cell Mechanics written by Horacio D. Espinosa and published by John Wiley & Sons. This book was released on 2012-12-12 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in nano and cell mechanics has received much attention from the scientific community as a result of society needs and government initiatives to accelerate developments in materials, manufacturing, electronics, medicine and healthcare, energy, and the environment. Engineers and scientists are currently engaging in increasingly complex scientific problems that require interdisciplinary approaches. In this regard, studies in this field draw from fundamentals in atomistic scale phenomena, biology, statistical and continuum mechanics, and multiscale modeling and experimentation. As a result, contributions in these areas are spread over a large number of specialized journals, which prompted the Editors to assemble this book. Nano and Cell Mechanics: Fundamentals and Frontiers brings together many of the new developments in the field for the first time, and covers fundamentals and frontiers in mechanics to accelerate developments in nano- and bio-technologies. Key features: • Provides an overview of recent advances in nano and cell mechanics. • Covers experimental, analytical, and computational tools used to investigate biological and nanoscale phenomena. • Covers fundamentals and frontiers in mechanics to accelerate developments in nano- and bio-technologies. • Presents multiscale-multiphysics modeling and experimentation techniques. • Examines applications in materials, manufacturing, electronics, medicine and healthcare. Nano and Cell Mechanics: Fundamentals and Frontiers is written by internationally recognized experts in theoretical and applied mechanics, applied physics, chemistry, and biology. It is an invaluable reference for graduate students of nano- and bio-technologies, researchers in academia and industry who are working in nano and cell mechanics, and practitioners who are interested in learning about the latest analysis tools. The book can also serve as a text for graduate courses in theoretical and applied mechanics, mechanical engineering, materials science, and applied physics.

Multiscale Models in Mechano and Tumor Biology

Author : Alf Gerisch
Publisher : Springer
ISBN 13 : 3319733710
Total Pages : 205 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Multiscale Models in Mechano and Tumor Biology by : Alf Gerisch

Download or read book Multiscale Models in Mechano and Tumor Biology written by Alf Gerisch and published by Springer. This book was released on 2018-03-16 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and discusses the state of the art and future perspectives in mathematical modeling and homogenization techniques with the focus on addressing key physiological issues in the context of multiphase healthy and malignant biological materials. The highly interdisciplinary content brings together contributions from scientists with complementary areas of expertise, such as pure and applied mathematicians, engineers, and biophysicists. The book also features the lecture notes from a half-day introductory course on asymptotic homogenization. These notes are suitable for undergraduate mathematics or physics students, while the other chapters are aimed at graduate students and researchers.

Handbook of Harnessing Biomaterials in Nanomedicine

Author : Dan Peer
Publisher : CRC Press
ISBN 13 : 100028428X
Total Pages : 454 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Handbook of Harnessing Biomaterials in Nanomedicine by : Dan Peer

Download or read book Handbook of Harnessing Biomaterials in Nanomedicine written by Dan Peer and published by CRC Press. This book was released on 2021-01-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine has emerged as a novel field in medicine integrating nano-scale technologies with materials sciences, chemistry and biology. The medical application of nanotechnology has the potential to revolutionize diagnosis and therapy and bring this new field from a notion into reality while impacting the lives of millions around the world. This second edition compiles and details the latest cutting-edge research in science and medicine from the interdisciplinary standpoint who are currently revolutionizing drug delivery techniques through the development of nanomedicines. Edited by Dan Peer, a prominent bio-nanotechnologiest, this book will attract anyone involved materials sciences, chemistry, biology and medicine that would like to design applications in the medical field of nanotechnology towards cancer therapy, inflammation, viral infection, imaging and toxicity.

Multiscale Modeling in Biomechanics and Mechanobiology

Author : Suvranu De
Publisher : Springer
ISBN 13 : 1447165993
Total Pages : 287 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Multiscale Modeling in Biomechanics and Mechanobiology by : Suvranu De

Download or read book Multiscale Modeling in Biomechanics and Mechanobiology written by Suvranu De and published by Springer. This book was released on 2014-10-10 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Multiscale Spatio-temporal Modeling of Cell Population in Tissue Architecture and Drug Delivery Nanoparticles

Author : Mohammad Aminul Islam
Publisher :
ISBN 13 :
Total Pages : 115 pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Multiscale Spatio-temporal Modeling of Cell Population in Tissue Architecture and Drug Delivery Nanoparticles by : Mohammad Aminul Islam

Download or read book Multiscale Spatio-temporal Modeling of Cell Population in Tissue Architecture and Drug Delivery Nanoparticles written by Mohammad Aminul Islam and published by . This book was released on 2019 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Multiscale nature of a biological system span at many order of magnitudes in time and space. Molecular interaction at lower scale is connected with the higher scale behavior of tissue or organism. Integrating the dynamics and information at different time and space can give a fundamental physiological understanding of the higher level phenomena. But complex features, functions, interconnectivity between different scales and lack of information on the fundamental physiological property make the model difficult and computationally challenging. The multiscale modeling approach can bridge the gap between different scale by a systemic integration of the complex dynamic behavior. Here, the focus is on developing multiscale modeling approaches to study the dynamic behavior of tissue. First, a multiscale spatiotemporal model is designed to investigate the tissue scale dispersion and penetration of nanoparticles from lower scale particle-cell interaction. The results obtained suggest that the size of nanoparticles may play less significant roles in tissue scale penetration and dispersion. The effect of nanoparticle size is less prominent due to the presence of particle-cell interaction and advection. This scalable spatiotemporal model can simulate the dynamics of drug delivery particles in the extracellular domain of a tissue. Furthermore, a parallel framework is developed to study the collective behavior of the cell population in a tissue architecture from their intracellular and extracellular reaction kinetics. The framework can model population dynamics at the tissue scale from a single cell biochemical reaction network accurately and efficiently. Finally, the framework's capability is demonstrated by simulating a full-scale model of bacterial quorum sensing, where the dynamics of a population of bacterial cells is dictated by the intercellular communications in a time-evolving growth environment"--Abstract, page iii.

Advances in Computational Fluid-Structure Interaction and Flow Simulation

Author : Yuri Bazilevs
Publisher : Birkhäuser
ISBN 13 : 3319408275
Total Pages : 487 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Advances in Computational Fluid-Structure Interaction and Flow Simulation by : Yuri Bazilevs

Download or read book Advances in Computational Fluid-Structure Interaction and Flow Simulation written by Yuri Bazilevs and published by Birkhäuser. This book was released on 2016-10-04 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume celebrates the work of Tayfun E. Tezduyar on the occasion of his 60th birthday. The articles it contains were born out of the Advances in Computational Fluid-Structure Interaction and Flow Simulation (AFSI 2014) conference, also dedicated to Prof. Tezduyar and held at Waseda University in Tokyo, Japan on March 19-21, 2014. The contributing authors represent a group of international experts in the field who discuss recent trends and new directions in computational fluid dynamics (CFD) and fluid-structure interaction (FSI). Organized into seven distinct parts arranged by thematic topics, the papers included cover basic methods and applications of CFD, flows with moving boundaries and interfaces, phase-field modeling, computer science and high-performance computing (HPC) aspects of flow simulation, mathematical methods, biomedical applications, and FSI. Researchers, practitioners, and advanced graduate students working on CFD, FSI, and related topics will find this collection to be a definitive and valuable resource.

Micro and Nano Flow Systems for Bioanalysis

Author : Michael W. Collins
Publisher : Springer Science & Business Media
ISBN 13 : 1461443768
Total Pages : 220 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Micro and Nano Flow Systems for Bioanalysis by : Michael W. Collins

Download or read book Micro and Nano Flow Systems for Bioanalysis written by Michael W. Collins and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sensewhether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.

Computational Approaches in Biomedical Nano-Engineering

Author : Ayesha Sohail
Publisher : John Wiley & Sons
ISBN 13 : 3527344748
Total Pages : 296 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Computational Approaches in Biomedical Nano-Engineering by : Ayesha Sohail

Download or read book Computational Approaches in Biomedical Nano-Engineering written by Ayesha Sohail and published by John Wiley & Sons. This book was released on 2018-08-31 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively and systematically treats modern understanding of the Nano-Bio-Technology and its therapeutic applications. The contents range from the nanomedicine, imaging, targeted therapeutic applications, experimental results along with modelling approaches. It will provide the readers with fundamentals on computational and modelling aspects of advanced nano-materials and nano-technology specifically in the field of biomedicine, and also provide the readers with inspirations for new development of diagnostic imaging and targeted therapeutic applications.

Intracellular Delivery

Author : Aleš Prokop
Publisher : Springer Science & Business Media
ISBN 13 : 9400712480
Total Pages : 871 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Intracellular Delivery by : Aleš Prokop

Download or read book Intracellular Delivery written by Aleš Prokop and published by Springer Science & Business Media. This book was released on 2011-05-26 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features a special subsection of Nanomedicine, an application of nanotechnology to achieve breakthroughs in healthcare. It exploits the improved and often novel physical, chemical and biological properties of materials only existent at the nanometer scale. As a consequence of small scale, nanosystems in most cases are efficiently uptaken by cells and appear to act at the intracellular level. Nanotechnology has the potential to improve diagnosis, treatment and follow-up of diseases, and includes targeted drug delivery and regenerative medicine; it creates new tools and methods that impact significantly upon existing conservative practices. This volume is a collection of authoritative reviews. In the introductory section we define the field (intracellular delivery). Then, the fundamental routes of nanodelivery devices, cellular uptake, types of delivery devices, particularly in terms of localized cellular delivery, both for small drug molecules, macromolecular drugs and genes; at the academic and applied levels, are covered. The following section is dedicated to enhancing delivery via special targeting motifs followed by the introduction of different types of intracellular nanodelivery devices (e.g. a brief description of their chemistry) and ways of producing these different devices. Finally, we put special emphasis on particular disease states and on other biomedical applications, whilst diagnostic and sensing issues are also included. Intracellular delivery / therapy is a highly topical which will stir great interest. Intracellular delivery enables much more efficient drug delivery since the impact (on different organelles and sites) is intracellular as the drug is not supplied externally within the blood stream. There is great potential for targeted delivery with improved localized delivery and efficacy.

Fundamentals of Multiscale Modeling of Structural Materials

Author : Wenjie Xia
Publisher : Elsevier
ISBN 13 : 0128230533
Total Pages : 450 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Fundamentals of Multiscale Modeling of Structural Materials by : Wenjie Xia

Download or read book Fundamentals of Multiscale Modeling of Structural Materials written by Wenjie Xia and published by Elsevier. This book was released on 2022-11-26 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Multiscale Modeling of Structural Materials provides a robust introduction to the computational tools, underlying theory, practical applications, and governing physical phenomena necessary to simulate and understand a wide-range of structural materials at multiple time and length scales. The book offers practical guidelines for modeling common structural materials with well-established techniques, outlining detailed modeling approaches for calculating and analyzing mechanical, thermal and transport properties of various structural materials such as metals, cement/concrete, polymers, composites, wood, thin films, and more.Computational approaches based on artificial intelligence and machine learning methods as complementary tools to the physics-based multiscale techniques are discussed as are modeling techniques for additively manufactured structural materials. Special attention is paid to how these methods can be used to develop the next generation of sustainable, resilient and environmentally-friendly structural materials, with a specific emphasis on bridging the atomistic and continuum modeling scales for these materials. Synthesizes the latest cutting-edge computational multiscale modeling techniques for an array of structural materials Emphasizes the foundations of the field and offers practical guidelines for modeling material systems with well-established techniques Covers methods for calculating and analyzing mechanical, thermal and transport properties of various structural materials such as metals, cement/concrete, polymers, composites, wood, and more Highlights underlying theory, emerging areas, future directions and various applications of the modeling methods covered Discusses the integration of multiscale modeling and artificial intelligence

Nanobiomaterials

Author : Anil K. Sharma
Publisher : CRC Press
ISBN 13 : 135179244X
Total Pages : 328 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Nanobiomaterials by : Anil K. Sharma

Download or read book Nanobiomaterials written by Anil K. Sharma and published by CRC Press. This book was released on 2018-01-03 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume focuses on the ever-growing and ever-sophisticated use of nanobiomaterials in drug delivery. There have been significant developments in the delivery of the active pharmaceutical ingredients to target sites, thereby sparing the normal functioning biological systems from damage, and this volume highlights some of the most important developments in the field. The book first provides an overview of nanobiomaterials and then goes on to report on new developments in drug delivery and nanotechnology, nanobiomaterials as carriers in cancer therapy, and the diverse uses of nanobiomaterials. Broken into sections, the chapters cover: an overview of nanobiomaterials drug delivery and nanotechnology nanobiomaterials as carriers in cancer therapeutics diverse uses of nanobiomaterials This volume will be a valuable resource on drug delivery for pharmaceutical manufacturers, healthcare personnel, and researchers.