Multiple Sclerosis Bench To Bedside

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Multiple Sclerosis: Bench to Bedside

Author : Alexzander A. A. Asea
Publisher : Springer
ISBN 13 : 3319478613
Total Pages : 188 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Multiple Sclerosis: Bench to Bedside by : Alexzander A. A. Asea

Download or read book Multiple Sclerosis: Bench to Bedside written by Alexzander A. A. Asea and published by Springer. This book was released on 2017-01-16 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis (MS) is one of the main causes of disability in young adult population. The estimated burden of the disease worldwide is about three million people. The pathogenic mechanism of MS involves both auto immune and degenerative processes. These two mechanisms are thought to determine a combination of events leading to several clinical pattern of disease onset and course. Multiple Sclerosis: Bench to Bedside provides the most up-to-date and concise reviews on the critical issues of multiple sclerosis from around the world. This book is written by leaders and experts in the field of multiple sclerosis research and is divided into easy to read sections. Section I focuses on basic science aspects of Multiple Sclerosis, including potential biomarkers, molecular biology, heat shock proteins, oxidative stress, genetic and epigenetics. Section II focuses on clinical and epidemiological aspects of Multiple Sclerosis, including remyelination therapy, neuroplasticity-based technologies and interventions. This is an important reference book and a must-read for Postgraduate Medical Scholars, Basic Science Researchers and Neurologists in Clinical Practice.

Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients

Download Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients PDF Online Free

Author : Paulus Stefan Rommer
Publisher : Frontiers Media SA
ISBN 13 : 288963566X
Total Pages : 253 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients by : Paulus Stefan Rommer

Download or read book Multiple Sclerosis – From Bench to Bedside: Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients written by Paulus Stefan Rommer and published by Frontiers Media SA. This book was released on 2020-03-13 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Sclerosis - From Bench to Bedside: Currents Insights Into Pathophysiological Concepts and Their Potential Impact on Patients

Author : Paulus Stefan Rommer
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Multiple Sclerosis - From Bench to Bedside: Currents Insights Into Pathophysiological Concepts and Their Potential Impact on Patients by : Paulus Stefan Rommer

Download or read book Multiple Sclerosis - From Bench to Bedside: Currents Insights Into Pathophysiological Concepts and Their Potential Impact on Patients written by Paulus Stefan Rommer and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and advances in the treatment of Multiple Sclerosis (MS) is a story of growing success. Great progress has been made in identifying the molecular mechanisms that can be utilized to develop highly efficacious treatments for MS patients. Since the middle of the last century, when studies using an inflammatory autoimmune model of MS i.e. experimental autoimmune encephalitis (EAE) were initiated, research on MS has since led to an enormous growth of knowledge. The limitations arising from these animal models have been partially compensated by insights generated from histopathological, immunological, genetic, imaging and clinical studies of MS. The importance of T cells and, recently of B cells, in MS has been elucidated and the significance of CNS resident cells, particularly in the progressive course of MS has been highlighted. The importance of environmental factors and genetic predisposition have also been recognized and the interaction between th e individual and its environment seems to play key roles in the pathogenesis of this disease. However, definite causative agent(s) or single gene(s) involved in MS still remain unidentified. A deeper understanding of the immunological pathways involved goes hand in hand with further improving therapy for MS. Focal inflammation in MS, caused by de novo CNS infiltration, can be prevented effectively using peripherally-acting drugs. However, diffuse CNS intrinsic inflammation and neurodegeneration are not targeted by the current arsenal of therapeutics and patients with progressive disease courses remain difficult to treat. Generating insights into pathophysiological processes and the clinical translation of this knowledge have been a formula of success for treating inflammatory diseases. The future will show whether this will hold true for CNS-trapped inflammation and neurodegeneration and whether the ultimate goal - truly curing MS - will be possible.

Primer on Multiple Sclerosis

Author : Barbara S. Giesser
Publisher : Oxford University Press
ISBN 13 : 019934101X
Total Pages : 613 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Primer on Multiple Sclerosis by : Barbara S. Giesser

Download or read book Primer on Multiple Sclerosis written by Barbara S. Giesser and published by Oxford University Press. This book was released on 2016 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive overview of the clinical and basic science aspects of MS. It is designed to be of practical use to clinical neurologists, and addresses all of the major issues that may occur in the management of persons with MS.

Neuroplasticity

Author : Angelo Quartarone
Publisher : Elsevier
ISBN 13 : 9780128194102
Total Pages : 518 pages
Book Rating : 4.1/5 (941 download)

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Book Synopsis Neuroplasticity by : Angelo Quartarone

Download or read book Neuroplasticity written by Angelo Quartarone and published by Elsevier. This book was released on 2022-03-15 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook of Clinical Neurology volume provides a comprehensive multidisciplinary guide to neuroplasticity. Part I of the book summarizes the basic mechanisms of neuroplasticity. Part II focuses on neuroplasticity in movement disorders. Part III focuses on brain oscillations in neurological disorders. Part IV segues into plasticity in neurorehabilitation. Part V summarizes issues of inflammation and autoimmunity in neuroplasticity. The book concludes with part VI on neuroplasticity and psychiatric disorders. Covers basic mechanisms to clinical treatment of neurological disorders Includes inflammation, autoimmunity, genetics, neurophysiology and more Encompasses stroke, Alzheimer's, movement, and psychiatric disorders Provides tools for enhancing recovery

Multiple Sclerosis for the Non-Neurologist

Author : Mary Ann Picone
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975102525
Total Pages : 687 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Multiple Sclerosis for the Non-Neurologist by : Mary Ann Picone

Download or read book Multiple Sclerosis for the Non-Neurologist written by Mary Ann Picone and published by Lippincott Williams & Wilkins. This book was released on 2019-05-07 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent rapid changes in the field of multiple sclerosis management have made the task of staying well-informed a challenge for neurologists, and even more so for other healthcare practitioners who are involved in symptom evaluation and treatment. Multiple Sclerosis for the Non-Neurologist is an up-to-date resource for physicians, residents, fellows, and others who care for patients with MS. It contains authoritative information on all aspects of this complex disease, including monitoring requirements for patients with MS, potential risks and adverse events of disease modifying or symptomatic therapies, and possible drug interactions and contraindications of medications.

Report and Recommendations of the National Advisory Commission on Multiple Sclerosis

Author : National Advisory Commission on Multiple Sclerosis
Publisher :
ISBN 13 :
Total Pages : 470 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Report and Recommendations of the National Advisory Commission on Multiple Sclerosis by : National Advisory Commission on Multiple Sclerosis

Download or read book Report and Recommendations of the National Advisory Commission on Multiple Sclerosis written by National Advisory Commission on Multiple Sclerosis and published by . This book was released on 1974 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Translational Neuroimmunology, Volume 8

Author : Nima Rezaei
Publisher : Elsevier
ISBN 13 : 0443185794
Total Pages : 272 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Translational Neuroimmunology, Volume 8 by : Nima Rezaei

Download or read book Translational Neuroimmunology, Volume 8 written by Nima Rezaei and published by Elsevier. This book was released on 2023-06-16 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. Provides an introduction on multiple sclerosis as an autoimmune disease, from bench to bedside Encourages the development of immunologic approaches to analyze the interaction and specific properties of nervous tissue elements during development and disease Focuses on understanding and therapeutically manipulating immunological responses to injury, degeneration and autoimmunity in the central nervous system Shows the changes in relevant immune and inflammatory reactions at the cellular and molecular level during the development of nervous system diseases

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

Author :
Publisher : John Wiley & Sons
ISBN 13 : 111953030X
Total Pages : 6057 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set by :

Download or read book Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set written by and published by John Wiley & Sons. This book was released on 2021-04-20 with total page 6057 pages. Available in PDF, EPUB and Kindle. Book excerpt: Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Advances in Multiple Sclerosis Research—Series I

Author : John Matsoukas
Publisher : MDPI
ISBN 13 : 3039439472
Total Pages : 334 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Advances in Multiple Sclerosis Research—Series I by : John Matsoukas

Download or read book Advances in Multiple Sclerosis Research—Series I written by John Matsoukas and published by MDPI. This book was released on 2021-04-19 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designing immunotherapeutics, drugs, and anti-inflammatory reagents has been at the forefront of autoimmune research, in particular multiple sclerosis, for over 20 years. Delivery methods that are used to modulate effective and long-lasting immune responses have been the major focus. This Special Issue focused on delivery methods to be used for vaccines, immunotherapeutic approaches, drug design, and anti-inflammatories and their outcomes in preclinical studies and clinical trials.

Primer on Multiple Sclerosis

Author : Barbara S. Giesser, MD
Publisher : Oxford University Press
ISBN 13 : 9780199708970
Total Pages : 504 pages
Book Rating : 4.7/5 (89 download)

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Book Synopsis Primer on Multiple Sclerosis by : Barbara S. Giesser, MD

Download or read book Primer on Multiple Sclerosis written by Barbara S. Giesser, MD and published by Oxford University Press. This book was released on 2010-12-01 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primer on Multiple Sclerosis was developed to provide a comprehensive overview of the clinical and basic science aspects of MS. It is designed to be of practical use to clinical neurologists, and addresses all of the major issues that may occur in the management of persons with MS. The reader is provided with the latest information on the science of MS, including immunology, genetics, epidemiology and pathology, as well as a summary of the newest directions in basic science research. Guidelines for diagnosis and appropriate use of diagnostic modalities are presented. All clinical aspects of MS are discussed, including extensive information on aspects that may be more challenging for the neurologist to manage, such as sleep disorders and pain. Disease modifying therapies, including those that are FDA approved, as well as off label and experimental therapies are discussed. Finally, there are chapters on employment and legal issues, as well as an overview of clinical trials and clinical trial outcome measures, which are helpful in reviewing the scientific literature in these areas.

Disease Modifying Therapies in Multiple Sclerosis

Author : Mahsa Ghajarzadeh
Publisher : Frontiers Media SA
ISBN 13 : 2832501303
Total Pages : 287 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Disease Modifying Therapies in Multiple Sclerosis by : Mahsa Ghajarzadeh

Download or read book Disease Modifying Therapies in Multiple Sclerosis written by Mahsa Ghajarzadeh and published by Frontiers Media SA. This book was released on 2022-09-30 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Conditions in Occupational Therapy

Author : Ben Atchison
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975215583
Total Pages : 1218 pages
Book Rating : 4.9/5 (752 download)

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Book Synopsis Conditions in Occupational Therapy by : Ben Atchison

Download or read book Conditions in Occupational Therapy written by Ben Atchison and published by Lippincott Williams & Wilkins. This book was released on 2023-04-03 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated 6th Edition is fully aligned with the most current DSM-5 and Occupational Therapy Practice Framework, 4th Edition, and adds new chapters reflecting recent advances in the management of infectious diseases, general deconditioning, musculoskeletal pain, amputations, and sickle cell anemia. Each chapter follows a consistent format, presenting an opening case followed by descriptions and definitions, etiology, incidence and prevalence, signs and symptoms, diagnosis, course and prognosis, medical/surgical management, impact on occupational performance, and two case illustrations. Rounded out with robust instructor resources and new full-color imagery, this bestselling resource is an essential tool for today’s occupational therapy and occupational therapy assistant students.

Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis

Download Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis PDF Online Free

Author : Maria Teresa Cencioni
Publisher : Frontiers Media SA
ISBN 13 : 2832520146
Total Pages : 220 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis by : Maria Teresa Cencioni

Download or read book Reassessing the immune system contribution in multiple sclerosis: Therapeutic target, biomarkers of disease and immune pathogenesis written by Maria Teresa Cencioni and published by Frontiers Media SA. This book was released on 2023-04-10 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:

There's No Pill for This

Author : Michaël Friedman
Publisher : Chelsea Green Publishing
ISBN 13 : 1603589732
Total Pages : 240 pages
Book Rating : 4.6/5 (35 download)

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Book Synopsis There's No Pill for This by : Michaël Friedman

Download or read book There's No Pill for This written by Michaël Friedman and published by Chelsea Green Publishing. This book was released on 2020-11-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: "I truly recommend There’s No Pill for This because it contains the wisdom of a health care professional who also has the experience of being a patient."—Bernie Siegel, MD, author of No Endings, Only Beginnings and Love, Medicine & Miracles From a doctor living with MS: how to radically improve your quality of life with diet, hormones, supplements, exercise, and other lifestyle adjustments Most of us take for granted the little things in life—like walking out to the mailbox, socializing with friends, or enjoying a mug of hot coffee. But what if each daily activity required intensive planning and effort? That’s what living with multiple sclerosis is like, and author Michaël Friedman knows this from first-hand experience. Since his diagnosis of multiple sclerosis a decade ago, Dr. Friedman has been searching for a cure for the disease. After years of research, he realized that he had some of the answers right in his naturopathic medicine toolbox, and others, surprisingly, lay in the realm of conventional medicine. There’s No Pill for This tells his story and offers treatment advice and hope to those who suffer from MS. He does not promise a miracle cure but instead provides the personal prescriptions he follows that are delaying the disease process and radically improving his quality of life, including dietary measures and supplements to support a healthy microbiome and hormone therapies that can reduce neuroinflammation and possibly promote neurorestoration. Dr. Friedman presents a daily protocol for MS patients, including diet, supplement, detoxification, and hormone strategies; mindfulness therapy; physical therapy; and a wide range of beneficial lifestyle adjustments related to exercise, sleep routines, time management, stress management, and more. He also offers special advice for supporting healthy bladder and bowel function and improving oxygen supply. In the book’s conclusion, Dr. Friedman reflects on what this complicated chronic disease has taught him, and continues to teach him, about the value of humility and about what is truly important in life.

Role of Oxidative Stress in Chronic Diseases

Author : Isaias Dichi
Publisher : CRC Press
ISBN 13 : 1482216825
Total Pages : 716 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Role of Oxidative Stress in Chronic Diseases by : Isaias Dichi

Download or read book Role of Oxidative Stress in Chronic Diseases written by Isaias Dichi and published by CRC Press. This book was released on 2014-03-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent findings on the role of oxidative stress in chronic diseases. Understanding the mechanisms behind it enables readers to comprehend the rationale which underlies intervention in such conditions. The book places special emphasis on genetic polymorphism-an important issue related to this field of study. It covers the role of

Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464901252
Total Pages : 185 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Multiple Sclerosis. The editors have built Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Multiple Sclerosis in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Multiple Sclerosis: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.