Amorphous Solid Dispersions

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Publisher : Springer
ISBN 13 : 1493915983
Total Pages : 702 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Amorphous Solid Dispersions by : Navnit Shah

Download or read book Amorphous Solid Dispersions written by Navnit Shah and published by Springer. This book was released on 2014-11-21 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.

Multidimensional Solid-state Nuclear Magnetic Resonance Spectroscopy of Pharmaceuticals and Polymers

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Publisher :
ISBN 13 :
Total Pages : 432 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Multidimensional Solid-state Nuclear Magnetic Resonance Spectroscopy of Pharmaceuticals and Polymers by : Mark Thomas Zell

Download or read book Multidimensional Solid-state Nuclear Magnetic Resonance Spectroscopy of Pharmaceuticals and Polymers written by Mark Thomas Zell and published by . This book was released on 2000 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Solid-State Nmr of Polymers

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Author :
Publisher : iSmithers Rapra Publishing
ISBN 13 : 9781859572726
Total Pages : 160 pages
Book Rating : 4.5/5 (727 download)

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Book Synopsis Solid-State Nmr of Polymers by : P. Mirau

Download or read book Solid-State Nmr of Polymers written by P. Mirau and published by iSmithers Rapra Publishing. This book was released on 2001 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy has emerged as one of the most important methods for the solid-state characterisation of polymers. This report gives an overview of the methods and applications of NMR to relevant polymer problems with an emphasis on how NMR can be used for materials characterisation and to understand structure-property relationships in polymers. An additional indexed section containing several hundred abstracts from the Rapra Polymer Library database gives useful references for further reading.

Multidimensional Solid-State NMR and Polymers

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Author :
Publisher : Elsevier
ISBN 13 : 0080925626
Total Pages : 501 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Multidimensional Solid-State NMR and Polymers by : Klaus Schmidt-Rohr

Download or read book Multidimensional Solid-State NMR and Polymers written by Klaus Schmidt-Rohr and published by Elsevier. This book was released on 2012-12-02 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: NMR spectroscopy is the most valuable and versatile analytical tool in chemistry. While excellent monographs exist on high-resolution NMR in liquids and solids, this is the first book to address multidimensional solid-state NMR. Multidimensional techniques enable researchers to obtain detailed information about the structure, dynamics, orientation, and phase separation of solids, which provides the basis of a better understanding of materials properties on the molecular level.Dramatic progress-much of it pioneered by the authors-has been achieved in this area, especially in synthetic polymers. Solid-state NMR now favorably competes with well-established techniques, such as light, x-ray, or neutron scattering, electron microscopy, and dielectric and mechanical relaxation.The application of multidimensional solid-state NMR inevitably involves use of concepts from different fields of science. This book also provides the first comprehensive treatment of both the new experimental techniques and the theoretical concepts needed in more complex data analysis. The text addresses spectroscopists and polymer scientists by treating the subject on different levels; descriptive, technical, and mathematical approaches are used when appropriate. It presents an overview of new developments with numerous experimental examples and illustrations, which will appeal to readers interested in both the information content as well as the potential of solid-state NMR. The book also contains many previously unpublished details that will be appreciated by those who want to perform the experiments. The techniques described are applicable not only to the study of synthetic polymers but to numerous problems in solid-state physics, chemistry, materials science, and biophysics. Presents original theories and new perspectives on scattering techniques Provides a systematic treatment of the whole subject Gives readers access to previously unpublished material Includes extensive illustrations

Solid State NMR Spectroscopy for Biopolymers

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402043031
Total Pages : 455 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Solid State NMR Spectroscopy for Biopolymers by : Hazime Saitô

Download or read book Solid State NMR Spectroscopy for Biopolymers written by Hazime Saitô and published by Springer Science & Business Media. This book was released on 2006-08-05 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘‘Biopolymers’’ are polymeric materials of biological origin, including globular, membrane, and fibrous proteins, polypeptides, nucleic acids, po- saccharides, lipids, etc. and their assembly, although preference to respe- ive subjects may be different among readers who are more interested in their biological significance or industrial and/or medical applications. Nevert- less, characterizing or revealing their secondary structure and dynamics may be an equally very important and useful issue for both kinds of readers. Special interest in revealing the 3D structure of globular proteins, nucleic acids, and peptides was aroused in relation to the currently active Structural Biology. X-ray crystallography and multidimensional solution NMR sp- troscopy have proved to be the standard and indispensable means for this purpose. There remain, however, several limitations to this end, if one intends to expand its scope further. This is because these approaches are not always straightforward to characterize fibrous or membrane proteins owing to extreme difficulty in crystallization in the former, and insufficient spectral resolution due to sparing solubility or increased effective molecular mass in the presence of surrounding lipid bilayers in the latter.

Multidimensional Solid-State Nmr

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Publisher :
ISBN 13 : 9780126575767
Total Pages : 500 pages
Book Rating : 4.5/5 (757 download)

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Book Synopsis Multidimensional Solid-State Nmr by : Hans Wolfgang Spiess

Download or read book Multidimensional Solid-State Nmr written by Hans Wolfgang Spiess and published by . This book was released on 2004-10-01 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nuclear Magnetic Resonance Volume 47

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839163917
Total Pages : 299 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Nuclear Magnetic Resonance Volume 47 by : Paul Hodgkinson

Download or read book Nuclear Magnetic Resonance Volume 47 written by Paul Hodgkinson and published by Royal Society of Chemistry. This book was released on 2021-11-29 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of nuclear magnetic resonance span a wide range of scientific disciplines, from physics to medicine. For those wanting to become acquainted with NMR or seasoned practitioners, this is a valuable source of current methods and applications.

Polymer Hybrid Materials and Nanocomposites

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Author :
Publisher : William Andrew
ISBN 13 : 0128132957
Total Pages : 354 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polymer Hybrid Materials and Nanocomposites by : Tawfik Abdo Saleh

Download or read book Polymer Hybrid Materials and Nanocomposites written by Tawfik Abdo Saleh and published by William Andrew. This book was released on 2021-08-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymer Hybrid Materials and Composites: Fundamentals and Applications presents an introduction to the principles behind polymeric hybrid materials, providing both theoretical and practical information on the synthesis and application of these materials. It documents the latest innovations, ranging from materials development and characterization of properties, to applications. Sections cover the route from laboratory to industry, providing practical, actionable guidance to assist the scaling up process for applications in areas including energy technology, solar cells, water purification, medical devices, optical and electrical devices, and more. It is an essential introduction to the emerging technologies that are made possible by these advanced materials. Documents the latest innovations in the technology, thus enabling new applications Provides significant and detailed information on the engineering of hybrid materials for a wide range of areas, including energy, medical, and electronics, among others

Nuclear Magnetic Resonance

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847553826
Total Pages : 628 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Nuclear Magnetic Resonance by : G A Webb

Download or read book Nuclear Magnetic Resonance written by G A Webb and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids and Membranes". For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an in valuable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Structural Studies of Polymers by Solution Nmr

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Publisher : iSmithers Rapra Publishing
ISBN 13 : 9781859572481
Total Pages : 168 pages
Book Rating : 4.5/5 (724 download)

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Book Synopsis Structural Studies of Polymers by Solution Nmr by : H.N. Cheng

Download or read book Structural Studies of Polymers by Solution Nmr written by H.N. Cheng and published by iSmithers Rapra Publishing. This book was released on 2001 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solution-state NMR spectroscopy is generally regarded as the premier technique to characterise polymer structure. This report provides a timely review of the developments in the NMR of polymers in solution in the past few years. An additional indexed section containing several hundred abstracts from the Polymer Library gives useful references for further reading.

Solid State NMR of Polymers

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Publisher :
ISBN 13 : 9781489924759
Total Pages : 420 pages
Book Rating : 4.9/5 (247 download)

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Book Synopsis Solid State NMR of Polymers by : L. J. Mathias

Download or read book Solid State NMR of Polymers written by L. J. Mathias and published by . This book was released on 2014-01-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NMR Spectroscopy of Polymers

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Author :
Publisher : OUP USA
ISBN 13 : 9780841226678
Total Pages : 0 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis NMR Spectroscopy of Polymers by : H.N. Cheng

Download or read book NMR Spectroscopy of Polymers written by H.N. Cheng and published by OUP USA. This book was released on 2012-04-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes review and papers on the latest advances by acknowledged leaders and active researchers in nuclear magnetic resonance (NMR) spectroscopy

Principles and Practices of Lyophilization in Product Development and Manufacturing

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Publisher : Springer Nature
ISBN 13 : 3031126343
Total Pages : 621 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Principles and Practices of Lyophilization in Product Development and Manufacturing by : Feroz Jameel

Download or read book Principles and Practices of Lyophilization in Product Development and Manufacturing written by Feroz Jameel and published by Springer Nature. This book was released on 2023-04-24 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T cell engager ( BITES), Dual Variable Domain ( DVD), Chimeric Antigen Receptor - Modified Tcells (CART) that are currently being used as therapeutic agents for immunology and oncology disease conditions. In addition to other pharmaceuticals and biopharmaceuticals, all these novel formats are fragile with respect to their stability/structure under processing conditions meaning marginal stability in the liquid state and often require lyophilization to enhance their stability and shelf-life. This book contains chapters/topics that will describe every aspect of the lyophilization process and product development and manufacturing starting from the overview of lyophilization process, equipment required, characterization of the material, design and development of the formulation and lyophilization process, various techniques for characterization of the product, scale-up/tech-transfer and validation. It also describes the application of CFD coupled with mathematical modeling in the lyophilization process and product development, scale-up, and manufacturing. Additionally, Principles and Practice of Lyophilization Process and Product Development contains an entire dedicated section on “Preservation of Biologicals” comprised of nine chapters written by experts and including case studies.

Experimental Approaches of NMR Spectroscopy

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Publisher : Springer
ISBN 13 : 9811059667
Total Pages : 636 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Experimental Approaches of NMR Spectroscopy by : The Nuclear Magnetic Resonance Society of Japan

Download or read book Experimental Approaches of NMR Spectroscopy written by The Nuclear Magnetic Resonance Society of Japan and published by Springer. This book was released on 2017-11-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Nanomaterials for Theranostics and Tissue Engineering

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Publisher : Elsevier
ISBN 13 : 0128178396
Total Pages : 322 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Nanomaterials for Theranostics and Tissue Engineering by : Filippo Rossi

Download or read book Nanomaterials for Theranostics and Tissue Engineering written by Filippo Rossi and published by Elsevier. This book was released on 2020-08-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Theranostics and Tissue Engineering: Techniques, Trends and Applications provides information on the major methodologies for the application of nanomaterials in the medical field. In recent years, nanotechnology for medicine, commonly known as bionanotechnology, or nanomedicine, has revolutionized various types of medical treatment. This book is intended for practicing engineers and scientists, and includes detailed, readily applicable protocols. It focuses on 4 major themes, including the synthesis of nanosystems for controlled drug delivery, nanotechnology-enhanced sensing systems, the application of nanotechnologies to the synthesis of novel biomaterials, and safety issues related to the application of medicinal nanotechnology. Provides a comprehensive overview on how nanotechnology is being used to create new tissue engineering techniques Covers, in detail, the physicochemical fundamentals of bionanotechnologies Explores major applications in the fields of theranostics and tissue engineering Assesses important challenges and safety issues related to the implementation of nanotechnology in medicine

Modern Methods in Solid-state NMR

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788014197
Total Pages : 452 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Modern Methods in Solid-state NMR by : Paul Hodgkinson

Download or read book Modern Methods in Solid-state NMR written by Paul Hodgkinson and published by Royal Society of Chemistry. This book was released on 2018-04-05 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid-state NMR covers an enormous range of material types and experimental techniques. Although the basic instrumentation and techniques of solids NMR are readily accessible, there can be significant barriers, even for existing experts, to exploring the bewildering array of more sophisticated techniques. In this unique volume, a range of experts in different areas of modern solid-state NMR explain about their area of expertise, emphasising the “practical aspects” of implementing different techniques, and illustrating what questions can and cannot be addressed. Later chapters address complex materials, showing how different NMR techniques discussed in earlier chapters can be brought together to characterise important materials types. The volume as a whole focusses on topics relevant to the developing field of “NMR crystallography” – the use of solids NMR as a complement to diffraction crystallography. This book is an ideal complement to existing introductory texts and reviews on solid-state NMR. New researchers wanting to understand new areas of solid-state NMR will find each chapter to be the equivalent to spending time in the laboratory of an internationally leading expert, learning the hints and tips that make the difference between knowing about a technique and being ready to put it into action. With no equivalent on the market, it will be of interest to every solid-state NMR researcher (academic and postgraduate) working in the chemical sciences.

Solid State NMR Spectroscopy

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470999381
Total Pages : 592 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Solid State NMR Spectroscopy by : Melinda J. Duer

Download or read book Solid State NMR Spectroscopy written by Melinda J. Duer and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is for those familiar with solution-state NMR who are encountering solid-state NMR for the first time. It presents the current understanding and applications of solid-state NMR with a rigorous but readable approach, making it easy for someone who merely wishes to gain an overall impression of the subject without details. This dual requirement is met through careful construction of the material within each chapter. The book is divided into two parts: "Fundamentals" and "Further Applications." The section on Fundamentals contains relatively long chapters that deal with the basic theory and practice of solid-state NMR. The essential differences and extra scope of solid-state NMR over solution-state is dealt with in an introductory chapter. The basic techniques that all chapters rely on are collected into a second chapter to avoid unnecessary repetition later. Remaining chapters in the "Fundamentals" part deal with the major areas of solid-state NMR which all solid-state NMR spectroscopists should know about. Each begins with an overview of the topic that puts the chapter in context. The basic principles upon which the techniques in the chapter rely are explained in a separate section. Each of these chapters exemplifies the principles and techniques with the applications most commonly found in current practice. The "Further Applications" section contains a series of shorter chapters which describe the NMR techniques used in other, more specific areas. The basic principles upon which these techniques rely will be expounded only if not already in the Fundamentals part.