The Gastrointestinal Circulation

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041176
Total Pages : 127 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Gastrointestinal Circulation by : Peter R. Kvietys

Download or read book The Gastrointestinal Circulation written by Peter R. Kvietys and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography

Some Observations on Gastric Mucosal Blood Flow

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (27 download)

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Book Synopsis Some Observations on Gastric Mucosal Blood Flow by : P. R. F. Bell

Download or read book Some Observations on Gastric Mucosal Blood Flow written by P. R. F. Bell and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regional Gastric Mucosal Blood Flow in Man

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Publisher :
ISBN 13 :
Total Pages : 114 pages
Book Rating : 4.:/5 (73 download)

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Book Synopsis Regional Gastric Mucosal Blood Flow in Man by : Gary Maynard Soenen

Download or read book Regional Gastric Mucosal Blood Flow in Man written by Gary Maynard Soenen and published by . This book was released on 1990 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt:

UPPER GASTROINTESTINAL MUCOSAL

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Publisher : Open Dissertation Press
ISBN 13 : 9781374746848
Total Pages : 136 pages
Book Rating : 4.7/5 (468 download)

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Book Synopsis UPPER GASTROINTESTINAL MUCOSAL by : Leslee y. Ong

Download or read book UPPER GASTROINTESTINAL MUCOSAL written by Leslee y. Ong and published by Open Dissertation Press. This book was released on 2017-01-27 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Upper Gastrointestinal Mucosal Blood Flow in Health and Disease" by Leslee Y, Ong, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b3122325 Subjects: Gastrointestinal mucosa - Blood-vessels Regional blood flow Reflectance spectroscopy

Gut Dysfunction in Critical Illness

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Publisher : Springer
ISBN 13 : 9783642802263
Total Pages : 399 pages
Book Rating : 4.8/5 (22 download)

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Book Synopsis Gut Dysfunction in Critical Illness by : J.L. Rombeau

Download or read book Gut Dysfunction in Critical Illness written by J.L. Rombeau and published by Springer. This book was released on 2014-08-23 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dysfunction of the gastrointestinal tract in critically ill patients has recently become a focus of intensive research. This book, the first one on this topic, is a comprehensive overview of what is currently known about the role of the gut in patients requiring intensive care. The definitions and pathogenesis of intestinal dysfunction are critically evaluated. Currently available and potential new ways to monitor intestinal function in the intensive care setting are presented. Emphasis has been placed on the evaluation of therapeutic strategies in the prevention and treatment of gut dysfunction. Options for monitoring and treating gut dysfunction in critically ill patients are rapidly evolving. This volume provides state-of-the-art information for both clinicians and clinical researchers.

Gastro-intestinal Mucosal Blood Flow

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Publisher :
ISBN 13 : 9780443021190
Total Pages : 240 pages
Book Rating : 4.0/5 (211 download)

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Book Synopsis Gastro-intestinal Mucosal Blood Flow by : L. Peter Fielding

Download or read book Gastro-intestinal Mucosal Blood Flow written by L. Peter Fielding and published by . This book was released on 1980-01-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mucosal Blood Circulation and Its Influence on Passive Absorption in the Small Intestine

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Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Mucosal Blood Circulation and Its Influence on Passive Absorption in the Small Intestine by : Joar Svanvik

Download or read book Mucosal Blood Circulation and Its Influence on Passive Absorption in the Small Intestine written by Joar Svanvik and published by . This book was released on 1973 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Mesenteric Vascular Disease

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Publisher : Springer
ISBN 13 : 1493918478
Total Pages : 463 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Mesenteric Vascular Disease by : Gustavo S. Oderich

Download or read book Mesenteric Vascular Disease written by Gustavo S. Oderich and published by Springer. This book was released on 2014-11-20 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.

Gastric Secretion, Motility and Mucosal Blood Flow

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Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Gastric Secretion, Motility and Mucosal Blood Flow by : DJ. Sanders

Download or read book Gastric Secretion, Motility and Mucosal Blood Flow written by DJ. Sanders and published by . This book was released on 1971 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Upper Gastrointestinal Mucosal Blood Flow in Health and Disease

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Publisher :
ISBN 13 :
Total Pages : 230 pages
Book Rating : 4.:/5 (513 download)

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Book Synopsis Upper Gastrointestinal Mucosal Blood Flow in Health and Disease by : Leslee Y. Ong

Download or read book Upper Gastrointestinal Mucosal Blood Flow in Health and Disease written by Leslee Y. Ong and published by . This book was released on 1999 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gastric Secretion, Motility and Mucosal Blood Flow

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Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.:/5 (184 download)

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Book Synopsis Gastric Secretion, Motility and Mucosal Blood Flow by : David J. Sanders

Download or read book Gastric Secretion, Motility and Mucosal Blood Flow written by David J. Sanders and published by . This book was released on 1971 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gastric Cytoprotection

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Publisher : Springer Science & Business Media
ISBN 13 : 1468456970
Total Pages : 228 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Gastric Cytoprotection by : Daniel Hollander

Download or read book Gastric Cytoprotection written by Daniel Hollander and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone.

Capillary Fluid Exchange

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615040668
Total Pages : 86 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Capillary Fluid Exchange by : Joshua Scallan

Download or read book Capillary Fluid Exchange written by Joshua Scallan and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation

Gastritis and Gastric Cancer

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Publisher : BoD – Books on Demand
ISBN 13 : 9533073756
Total Pages : 312 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Gastritis and Gastric Cancer by : Paola Tonino

Download or read book Gastritis and Gastric Cancer written by Paola Tonino and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.

Gastrointestinal Mucosal Defense System

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Publisher : Biota Publishing
ISBN 13 : 1615041486
Total Pages : 174 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Gastrointestinal Mucosal Defense System by : Peter R. Kvietys

Download or read book Gastrointestinal Mucosal Defense System written by Peter R. Kvietys and published by Biota Publishing. This book was released on 2014-11-01 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: The gastrointestinal mucosal defense system serves to minimize mucosal injury by either ingested or endogenously produced noxious substances. The mucosal defense system is stratified into pre-epithelial (alkaline mucus), epithelial (dynamic epithelial lining), and post-epithelial (microcirculation) components. The mucus lining the epithelial surface presents a diffusional barrier to ingested material (e.g., lipids) and also serves as an unstirred layer in which a pH gradient can be established to prevent acid-induced injury. The epithelial lining prevents entrance of any toxic material to the interstitium and, should it be damaged, it is rapidly resealed by migration of adjacent viable epithelial cells to cover the defect. Any acid or other material that has entered the interstitium is washed out by an intense neurogenic hyperemia. In general, the mucosal defense system is quite effective and any adverse gastrointestinal effects associated with the normal course of nutrient assimilation are minimal. However, there are two situations in which the mucosal defense system is known to be ineffective and result in gastric mucosal injury: inadvertent ingestion of H. pylori. or intentional ingestion of NSAIDs. H. pylori can penetrate the mucus layers and cause epithelial injury and inflammation, while at the same time preventing its clearance by the host immune system. NSAIDs weaken the mucus layer and cause epithelial cell injury. Table of Contents: Acknowledgments / Introduction / The Mucus Layer / Epithelial Lining / Gastrointestinal Circulation / Integration of Mucosal Defense / Mucosal Defense System: Physiologic / Mucosal Defense System: H. pylori / Mucosal Defense System: Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) / Overall Summary and Conclusions / References / Author Biographies

Physiology of the Gastrointestinal Tract, Two Volume Set

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Publisher : Academic Press
ISBN 13 : 0123820278
Total Pages : 2250 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Physiology of the Gastrointestinal Tract, Two Volume Set by : Hamid M. Said

Download or read book Physiology of the Gastrointestinal Tract, Two Volume Set written by Hamid M. Said and published by Academic Press. This book was released on 2012-07-04 with total page 2250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations