Mr Lentz From The Committee On Military Affairs Submitted The Following Report To Accompany H R 7796

Author : Grant N. Pierce
Publisher : Springer Science & Business Media
ISBN 13 : 9781402073113
Total Pages : 528 pages
Book Rating : 4.0/5 (731 download)

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Download or read book Atherosclerosis, Hypertension and Diabetes written by Grant N. Pierce and published by Springer Science & Business Media. This book was released on 2003-04-30 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is devoted to atherosclerosis, hypertension, anddiabetes, three of the most important disease conditions in the worldtoday. Nutritional intervention, cholesterol lowering agents, lipidsthemselves, particularly oxidized LDL, protein modification byADP-ribose, bone marrow study, endothelial cell dysfunction, angiotensin, and the role of infection and inflammation are alldiscussed in the context of atherosclerotic cardiovascular disease.The hypertension section focuses on factors that may be responsiblefor high blood pressure, such as genetic predisposition, vascularhyperplasia and remodeling, insulin resistance, neurological aspectssuch as hypothalamic peptides. Also discussed are the possiblecontributions of the cellular function of the endothelium, nutrition, kidney dysfunction, leptin, and the brain. Novel routes of drugdelivery for treatment of hypertension is also a focus.As for diabetes, the risk factors and mechanisms responsible fordiabetic vascular and cardiac dysfunction are discussed. Lipid profilechanges and fibrinolysis in diabetic patients is detailed, along withadipogenesis, diabetic cardiomyopathy, energy metabolism in thediabetic heart, vanadate as an alternative to insulin, insulinresistance mechanisms, and neurotransmitters as targets for theprevention of cardiovascular disease and diabetes.These manuscripts were invited from scientists who presented state ofthe art lectures at the XVII World Congress of the InternationalSociety for Heart Research held in Winnipeg in July 2001.