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Motor System Disorders Part Ii
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Book Synopsis Motor System Disorders, Part II by : David S. Younger
Download or read book Motor System Disorders, Part II written by David S. Younger and published by Elsevier. This book was released on 2023-08-22 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive review of research and best practice clinical management of spinal cord, neurodegenerative, and cerebral disorders is intended for both researchers and clinicians. Encompassing hereditary and acquired disorders from disease and accident, the book explores motor control disorders associated with stroke, dementia, seizure, encephalitis, and more. Covering disorders of both children and adults, the book discusses the latest advances in treatments related to neuroplasticity, neural tissue transplantation, and immunotherapy. - Summarizes assessment, disease course, and best practice treatment - Includes hereditary disorders and disorders from disease or accident - Discusses advances in neuroplasticity, tissue transplantation, immunotherapy, and other treatments - Reviews effects of dementia, stroke, seizure, encephalitis, cancer, and more
Book Synopsis Motor System Disorders, Part I by : David S. Younger
Download or read book Motor System Disorders, Part I written by David S. Younger and published by Elsevier. This book was released on 2023-08-08 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor System Disorders: Normal Physiology and Function and Neuromuscular Disorders summarizes recent advances and best practice for understanding normal physiology and function of the larger motor system as well as the diagnosis, course, and treatment of neuromuscular disorders. The work will include neuroanatomy, circuits and synapses. It discusses how different parts of the brain contribute to motor control, including both vestibular and cerebellar motor control, as well as the influences of the parietal and frontal lobes. Diagnostic methods include genetic evaluation, electrodiagnosis, pathology, and brain imaging. Neuromuscular disorders of both children and adults will be included. - Identifies normal motor control physiology and function, including neuroanatomy, circuits, and synapses - Discusses vestibular and cerebral motor control and contributions of parietal and frontal lobes - Provides diagnostic methods, including genetic evaluation, electrodiagnosis, brain imaging, and pathology analyses - Summarizes the diagnosis, course, and best practice treatment of neuromuscular disorders - Explores neuromuscular disorders in adults and children
Book Synopsis Inherited White Matter Disorders and Their Mimics by :
Download or read book Inherited White Matter Disorders and Their Mimics written by and published by Elsevier. This book was released on 2024-09-23 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathies) often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping. This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable. - Includes common and rare white matter disorders (WMDs) - Summarizes advances in genetics, radiology, and treatments for WMDs - Provides clinical and radiological phenotyping - Contains imaging, diagnostic algorithms, and guidance on treatment
Book Synopsis Cell and Gene Therapies for Neurologic Diseases by :
Download or read book Cell and Gene Therapies for Neurologic Diseases written by and published by Elsevier. This book was released on 2024-10-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson's, Huntington's, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs. - Summarizes advances in cell and gene therapy for neurological diseases - Describes the therapies available and in development - Includes surgical, ethical, and manufacturing considerations - Identifies best practices for specific neurological diseases - Covers Huntington's, Parkinson's, ALS, Stroke, Demyelination, epilepsy, and more
Book Synopsis Hematopoietic Stem Cell Transplantation for Neurologic Diseases by :
Download or read book Hematopoietic Stem Cell Transplantation for Neurologic Diseases written by and published by Elsevier. This book was released on 2024-08-05 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intense immunosuppression followed by Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT) has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis and many immune neuropathies. This volume summarizes that research. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to mew insights on the pathological mechanisms underlying CNS autoimmunity. - Reviews immunological mechanisms of HSCT and CNS autoimmunity - Identifies neurological diseases showing treatment efficacy with HSCT - Includes MS, myasthenia gravis, neuromyelitis optica, and more - Covers early and late side effects of HSCT
Download or read book Neurologic Channelopathies written by and published by Elsevier. This book was released on 2024-08-20 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies.Ion channels are critical membrane bound proteins that underpin many fundamental processes in the central and peripheral nervous system including action potential generation and propagation and the control of neurotransmitter release at all CNS synapses as well as at the neuromuscular junction. Ion channels are consequently essential for all motor actions, cognitive functions and sensory perceptions. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given the fundamental processes that are dependent on ion channel function, it is perhaps unsurprising that genetic or immunologically mediated ion channel dysfunction can result in almost any neurological symptom; patients may present to virtually any subspecialty within both adult and child neurology. The advances that have been made here have not only increased knowledge about the fundamental molecular mechanisms at play, but have also improved our ability to both diagnose and treat many of these disorders in clinical practice. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the Neurological Channelopathies.The book will begin with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations but with potential for common treatment approaches. This initial chapter considers the classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter will consider•Pathophysiological underpinnings - genetic or immunological•Clinical presentations•Diagnostic approach•Treatment and management - Identifies importance of ion channels to CNS & PNS function - Considers the classification, genetics, and physiology of ion channels - Presents all major immunological and genetic channelopathies - Provides clinical presentation, diagnosis, and treatment of channelopathies
Download or read book Focal Neuropathies written by and published by Elsevier. This book was released on 2024-04-30 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes research and treatment on focal neuropathies to update clinicians on nerve biology and new diagnostic techniques to guide investigation and treatment of mononeuropathies. The book explores research broadly applicable to all types of mononeuropathies as well as individual mononeuropathy syndromes. Chapters on individual mononeuropathies include anatomy, causes, controversial diagnoses, and current or potential future treatments. - Summarizes new research on treatment for focal neuropathies - Differentiates and advises on controversial diagnoses - Includes neuropathies by location as well as syndrome or type of neuropathy - Covers biology, diagnosis, imaging, etiology, and treatment
Download or read book Brain and Crime written by Hanna Swaab and published by Elsevier. This book was released on 2023-08-24 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain and Crime, Volume 197 reviews the relation between brain function and aggressive and rule-breaking (criminal) behavior. The book's focus is on the violation of social rules and not on violation of regulations that are different in different counties. It discusses the development of this behavior from childhood into adulthood, along with the mechanisms associated with the risk for aggression and rule-breaking behavior. In addition, it explores from a behavioral level concepts like psychopathology, syndrome and concepts from law, such as crime, defendant and offender. Finally, sections explore brain function, including emotion, cognitive processes, and decision-making. From the perspective of brain structure, the book covers brain networks and brain disorders. In genetics, the book includes the influence of genes and the mechanisms of epigenetics. All chapters are intended to provide information for use in the diagnosis and treatment of disorders, and in assessment and prevention. - Discusses the development of rule-breaking (criminal) behavior from childhood into adulthood - Covers the influence of genes and the mechanisms of epigenetics - Includes the diagnosis and treatment of disorders, along with assessment and prevention
Book Synopsis Migraine Management by : Jerry W. Swanson
Download or read book Migraine Management written by Jerry W. Swanson and published by Elsevier. This book was released on 2024-02-01 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine Management, Volume 196 covers the effective treatment of migraines, including different subtypes of migraines in different patient populations. The classification and diagnostic criteria of common and uncommon subtypes of migraine is explored in detail, including childhood variants. An in-depth analysis of the pharmacology of acute and prophylactic agents is presented, along with an evidence-based review of pharmacologic management. This includes recently developed CGRP monoclonal antibodies and non-peptide small molecule CGRP antagonists. Advances in neuromodulatory treatments, both noninvasive and implantable, are also critically reviewed. Finally, specific treatment-related issues in pregnancy and lactation and childhood as well as the elderly are covered. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness is also explored. - Summarizes evidence-based best treatment for migraines - Differentiates treatment based on patient population, migraine type, and clinical setting - Includes pharmacological, biobehavioral, and physical treatments - Provides specialized treatments for children, the elderly, and pregnant patients
Book Synopsis Migraine Biology, Diagnosis, and Co-Morbidities by : Jerry W. Swanson
Download or read book Migraine Biology, Diagnosis, and Co-Morbidities written by Jerry W. Swanson and published by Elsevier. This book was released on 2023-11-30 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Migraine Biology, Diagnosis, and Co-Morbidities, Volume 195 covers a wide range of issues related to migraine. The epidemiology, global and personal impacts of migraine are covered, including topics on the pathophysiology of migraine and migraine aura, the pathophysiology of the associated symptoms of photophobia and phonophobia, and the genetics of migraine. The classification and diagnostic criteria of common and uncommon subtypes of migraine are also explored in detail, including childhood variants. Issues related to the diagnosis and management of vestibular migraine and the co-morbid disorder of persistent postural-perceptual dizziness are also covered. The important comorbidities of migraine such as anxiety, depression and other forms of chronic pain will also be discussed, along with the current state and future directions of migraine research and management. - Summarizes research and clinical information on the pathophysiology of migraines - Explores the pathophysiology of aura, photophobia, and phonophobia - Discusses migraine triggers - Reviews migraine subtypes and comorbid conditions in migraine - Explores the relationship of migraine to chronic pain and cerebrovascular and psychological conditions - Concludes with future directions in migraine research and treatment
Book Synopsis Sleep Disorders Part II by : Pasquale Montagna
Download or read book Sleep Disorders Part II written by Pasquale Montagna and published by Elsevier. This book was released on 2012-11-27 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sleep Disorders II covers various aspects of sleep disorders. These include the different classification of sleep disorders, the genetic influences of sleep disorders, abnormality in the sleeping pattern, and the circadian rhythm sleep disorder. A sleep disorder is a medical disorder that affects the sleeping patterns of humans (and sometimes animals). The disruptions in sleep can be caused by different factors, such as teeth grinding, night terrors, and the like. The book also discusses different perspectives on insomnia and hypersomnia. According to the International Classification of Sleep Disorders, insomnia is a sleep that is low in quality or a difficulty in sleeping. On the other hand, hypersomnia is a sleeping disorder characterized by excessive daytime sleepiness (EDS) or prolonged nighttime sleep. The book discusses narcolepsy, a syndrome that is characterized by excessive daytime sleepiness that is associated with cataplexy and other REM sleep phenomena. The different medicines for this disease are also discussed. People who are practicing neurology and internal medicine, especially those in pulmonary, cardiovascular, gastrointestinal, renal and endocrine specialties, will find this book valuable. - A comprehensive resource for the study of sleep science, sleep medicine, and sleep disorders - Fascinating noninvasive neuroimaging studies that demonstrate marked changes during different sleep states - A state-of-the-art reference that summarizes the clinical features and management of many of the neurological manifestations of sleep disorders
Book Synopsis The Autoimmune Brain by : David S. Younger
Download or read book The Autoimmune Brain written by David S. Younger and published by Rowman & Littlefield. This book was released on 2019-11-10 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are millions of people who experience issues related to brain health—depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain—yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or anti-anxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age—from children to teens or seniors—people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. The Autoimmune Brain connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease; Anxiety; Arthritis; Autism; Autonomic disturbances; Bacterial and viral infections; Bipolar Disorder; Cancer; Celiac disease and gluten intolerances; Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease); Chronic Pain; Dementia; Depression; Endocrine Disorders; Immune modulatory therapy using IVIg; Lyme disease and co-infections; Mast cell activation syndrome; Medical cannabis; Obsessive Compulsive Disorder; Orthostatic hypotension; Peripheral Neuropathy; Porphyria; Post-Traumatic Stress Disorder; and Postural orthostatic tachycardia.
Book Synopsis Motor Disorders by : David S. Younger, MD
Download or read book Motor Disorders written by David S. Younger, MD and published by Rothstein Publishing. This book was released on 2014-10-01 with total page 1943 pages. Available in PDF, EPUB and Kindle. Book excerpt: This preeminent book in the field of Neurology has been extensively updated and expanded by 70 leading authorities, providing a single, encyclopedic summary the scientific advances and new clinical practices that can be immediately considered for your patients. It brings together nearly the entire spectrum of motor disorders and Neurology into one convenient resource to aid in a comprehensive evaluation, diagnosis, distinction, and treatment of various disorders. Additionally, by using the perspectives of different subspecialties, the book also provides a comprehensive yet concise account of any disorder with motor manifestations. This new edition now includes the following content and features: Edited by David S. Younger, MD, a highly respected practitioner and researcher, with scholarly chapters by leaders in the field and more international authors than other texts. Up-to-date articles on highly changing subjects related to Neurogenetics. Chapters on Neurorehabilitation – coverage not usually found in other neurological textbooks. Advances in Alzheimer Disease, Parkinson Disease, Amyotophic Lateral Sclerosis. Both adult and pediatric topics in one book. High quality figures of neuroimaging and neuropathology.
Book Synopsis Neurological, Psychiatric, and Developmental Disorders by : Institute of Medicine
Download or read book Neurological, Psychiatric, and Developmental Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2001-01-01 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain disordersâ€"neurological, psychiatric, and developmentalâ€"now affect at least 250 million people in the developing world, and this number is expected to rise as life expectancy increases. Yet public and private health systems in developing countries have paid relatively little attention to brain disorders. The negative attitudes, prejudice, and stigma that often surround many of these disorders have contributed to this neglect. Lacking proper diagnosis and treatment, millions of individual lives are lost to disability and death. Such conditions exact both personal and economic costs on families, communities, and nations. The report describes the causes and risk factors associated with brain disorders. It focuses on six representative brain disorders that are prevalent in developing countries: developmental disabilities, epilepsy, schizophrenia, bipolar disorder, depression, and stroke. The report makes detailed recommendations of ways to reduce the toll exacted by these six disorders. In broader strokes, the report also proposes six major strategies toward reducing the overall burden of brain disorders in the developing world.
Book Synopsis Neurology and Clinical Neuroscience E-Book by : Anthony H. V. Schapira
Download or read book Neurology and Clinical Neuroscience E-Book written by Anthony H. V. Schapira and published by Elsevier Health Sciences. This book was released on 2006-12-18 with total page 1653 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent information Integrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient. Discusses the latest research results and offers new information on treatment options. Features the expertise of international authorities, providing a worldwide perspective. Uses a templated, four-color format that makes information accessible and easy to understand—particularly the basic science concepts.
Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Book Synopsis Neuromuscular Disorders in Clinical Practice by : Bashar Katirji
Download or read book Neuromuscular Disorders in Clinical Practice written by Bashar Katirji and published by Springer Science & Business Media. This book was released on 2013-10-11 with total page 1565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes. Neuromuscular Disorders in Clinical Practice, Second Edition is intended to serve as a comprehensive text for both novice and experienced practitioners. General neurologists as well as specialists in neuromuscular medicine and trainees in neuromuscular medicine, clinical neurophysiology and electromyography should find this book inclusive, comprehensive, practical and highly clinically focused. Additionally, specialists in physical medicine and rehabilitation, rheumatology, neurosurgery, and orthopedics will find the book of great value in their practice.
