The Emperor of All Maladies

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Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Pharmaceuticals, Corporate Crime and Public Health

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Publisher : Edward Elgar Publishing
ISBN 13 : 1783471107
Total Pages : 419 pages
Book Rating : 4.7/5 (834 download)

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Book Synopsis Pharmaceuticals, Corporate Crime and Public Health by : Graham Dukes

Download or read book Pharmaceuticals, Corporate Crime and Public Health written by Graham Dukes and published by Edward Elgar Publishing. This book was released on 2014-06-27 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry exists to serve the community, but over the years it has engaged massively in corporate crime, with the public footing the bill. This readable study by experts in medicine, law, criminology and public health documents the pr

The United States Postal Service

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Publisher :
ISBN 13 : 9780963095244
Total Pages : pages
Book Rating : 4.0/5 (952 download)

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Book Synopsis The United States Postal Service by : United States Postal Service Staff

Download or read book The United States Postal Service written by United States Postal Service Staff and published by . This book was released on 2016-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural Resources, Neither Curse nor Destiny

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Publisher : World Bank Publications
ISBN 13 : 0821365460
Total Pages : 396 pages
Book Rating : 4.8/5 (213 download)

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Book Synopsis Natural Resources, Neither Curse nor Destiny by : Daniel Lederman

Download or read book Natural Resources, Neither Curse nor Destiny written by Daniel Lederman and published by World Bank Publications. This book was released on 2006-10-23 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Natural Resources: Neither Course nor Destiny' brings together a variety of analytical perspectives, ranging from econometric analyses of economic growth to historical studies of successful development experiences in countries with abundant natural resources. The evidence suggests that natural resources are neither a curse nor destiny. Natural resources can actually spur economic development when combined with the accumulation of knowledge for economic innovation. Furthermore, natural resource abundance need not be the only determinant of the structure of trade in developing countries. In fact, the accumulation of knowledge, infrastructure, and the quality of governance all seem to determine not only what countries produce and export, but also how firms and workers produce any good.

The New Urban Frontier

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Publisher : Routledge
ISBN 13 : 1134787464
Total Pages : 348 pages
Book Rating : 4.1/5 (347 download)

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Book Synopsis The New Urban Frontier by : Neil Smith

Download or read book The New Urban Frontier written by Neil Smith and published by Routledge. This book was released on 2005-10-26 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why have so many central and inner cities in Europe, North America and Australia been so radically revamped in the last three decades, converting urban decay into new chic? Will the process continue in the twenty-first century or has it ended? What does this mean for the people who live there? Can they do anything about it? This book challenges conventional wisdom, which holds gentrification to be the simple outcome of new middle-class tastes and a demand for urban living. It reveals gentrification as part of a much larger shift in the political economy and culture of the late twentieth century. Documenting in gritty detail the conflicts that gentrification brings to the new urban 'frontiers', the author explores the interconnections of urban policy, patterns of investment, eviction, and homelessness. The failure of liberal urban policy and the end of the 1980s financial boom have made the end-of-the-century city a darker and more dangerous place. Public policy and the private market are conspiring against minorities, working people, the poor, and the homeless as never before. In the emerging revanchist city, gentrification has become part of this policy of revenge.

Minor White, the Eye that Shapes

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Publisher : Art Museum Princeton University
ISBN 13 : 9780943012100
Total Pages : 289 pages
Book Rating : 4.0/5 (121 download)

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Book Synopsis Minor White, the Eye that Shapes by : Minor White

Download or read book Minor White, the Eye that Shapes written by Minor White and published by Art Museum Princeton University. This book was released on 1989-01-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying a major retrospective exhibition opening at The Museum of Modern Art and travelling until 1991, this is a publication of White's work using the artist's extensive personal archive bequeathed to Princeton University on his death.

Understanding War in Afghanistan

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Publisher :
ISBN 13 : 9780160888311
Total Pages : 0 pages
Book Rating : 4.8/5 (883 download)

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Book Synopsis Understanding War in Afghanistan by : Joseph J. Collins

Download or read book Understanding War in Afghanistan written by Joseph J. Collins and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Rural New-Yorker

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Publisher :
ISBN 13 :
Total Pages : 738 pages
Book Rating : 4.3/5 (126 download)

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Book Synopsis The Rural New-Yorker by :

Download or read book The Rural New-Yorker written by and published by . This book was released on 1931 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tau oligomers

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Publisher : Frontiers E-books
ISBN 13 : 288919261X
Total Pages : 114 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Tau oligomers by : Jesus Avila

Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.

Black Mail

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Publisher :
ISBN 13 :
Total Pages : 110 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Black Mail by : Henry Hoke

Download or read book Black Mail written by Henry Hoke and published by . This book was released on 1944 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hoke's exposé of fascist front groups in the United States in the late thirties and into the war years.

Plant Lipid Metabolism

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Publisher : Springer Science & Business Media
ISBN 13 : 9401583943
Total Pages : 598 pages
Book Rating : 4.4/5 (15 download)

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Book Synopsis Plant Lipid Metabolism by : J.C. Kader

Download or read book Plant Lipid Metabolism written by J.C. Kader and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of papers that comprehensively describe the major areas of research on lipid metabolism of plants. State-of-the-art knowledge about research on fatty acid and glycerolipid biosynthesis, isoprenoid metabolism, membrane structure and organization, lipid oxidation and degradation, lipids as intracellular and extracellular messengers, lipids and environment, oil seeds and gene technology is reviewed. The different topics covered show that modern tools of plant cellular and molecular biology, as well as molecular genetics, have been recently used to characterize several key enzymes of plant lipid metabolism (in particular, desaturases, thioesterases, fatty acid synthetase) and to isolate corresponding cDNAs and genomic clones, allowing the use of genetic engineering methods to modify the composition of membranes or storage lipids. These findings open fascinating perspectives, both for establishing the roles of lipids in membrane function and intracellular signalling and for adapting the composition of seed oil to the industrial needs. This book will be a good reference source for research scientists, advanced students and industrialists wishing to follow the considerable progress made in recent years on plant lipid metabolism and to envision the new opportunities offered by genetic engineering for the development of novel oil seeds.

Pioneer Days on Puget Sound

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Publisher : Franklin Classics
ISBN 13 : 9780343572549
Total Pages : 94 pages
Book Rating : 4.5/5 (725 download)

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Book Synopsis Pioneer Days on Puget Sound by : Arthur Armstrong Denny

Download or read book Pioneer Days on Puget Sound written by Arthur Armstrong Denny and published by Franklin Classics. This book was released on 2018-10-16 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

The World of UCL

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Publisher : UCL Press
ISBN 13 : 1787352943
Total Pages : 179 pages
Book Rating : 4.7/5 (873 download)

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Book Synopsis The World of UCL by : Negley Harte

Download or read book The World of UCL written by Negley Harte and published by UCL Press. This book was released on 2018-05-21 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: From its foundation in 1826, UCL embraced a progressive and pioneering spirit. It was the first university in England to admit students regardless of religion and made higher education affordable and accessible to a much broader section of society. It was also effectively the first university to welcome women on equal terms with men. From the outset UCL showed a commitment to innovative ideas and new methods of teaching and research. This book charts the history of UCL from 1826 through to the present day, highlighting its many contributions to society in Britain and around the world. It covers the expansion of the university through the growth in student numbers and institutional mergers. It documents shifts in governance throughout the years and the changing social and economic context in which UCL operated, including challenging periods of reconstruction after two World Wars. Today UCL is one of the powerhouses of research and teaching, and a truly global university. It is currently seventh in the QS World University Rankings. This completely revised and updated edition features a new chapter based on interviews with key individuals at UCL. It comes at a time of ambitious development for UCL with the establishment of an entirely new campus in East London, UCL East, and Provost Michael Arthur’s ‘UCL 2034’ strategy which aims to secure the university’s long-term future and commits UCL to delivering global impact.

Rural New Yorker

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Author :
Publisher :
ISBN 13 :
Total Pages : 1256 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Rural New Yorker by :

Download or read book Rural New Yorker written by and published by . This book was released on 1931 with total page 1256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Paths of Heaven The Evolution of Airpower Theory

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis The Paths of Heaven The Evolution of Airpower Theory by :

Download or read book The Paths of Heaven The Evolution of Airpower Theory written by and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Airpower is not widely understood. Even though it has come to play an increasingly important role in both peace and war, the basic concepts that define and govern airpower remain obscure to many people, even to professional military officers. This fact is largely due to fundamental differences of opinion as to whether or not the aircraft has altered the strategies of war or merely its tactics. If the former, then one can see airpower as a revolutionary leap along the continuum of war; but if the latter, then airpower is simply another weapon that joins the arsenal along with the rifle, machine gun, tank, submarine, and radio. This book implicitly assumes that airpower has brought about a revolution in war. It has altered virtually all aspects of war: how it is fought, by whom, against whom, and with what weapons. Flowing from those factors have been changes in training, organization, administration, command and control, and doctrine. War has been fundamentally transformed by the advent of the airplane.

Florida Jewish Heritage Trail

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Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Florida Jewish Heritage Trail by : Florida. Division of Historical Resources

Download or read book Florida Jewish Heritage Trail written by Florida. Division of Historical Resources and published by . This book was released on 2000 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traces the steps of Florida's Jewish pioneers from colonial times through the present through the historical sites in each county that reflect their heritage.

New Japanese Photography

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Publisher :
ISBN 13 : 9780870705021
Total Pages : 111 pages
Book Rating : 4.7/5 (5 download)

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Book Synopsis New Japanese Photography by : Shōji Yamagishi

Download or read book New Japanese Photography written by Shōji Yamagishi and published by . This book was released on 1974 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Within the past twenty-five years the character of Japanese photography has changed radically, and its former dependence on the patterns and attitudes of the traditional Japanese media has been replaced by a sometimes harshly realistic objectivity. At the root of this change was a desire to find ways in which photography could deal directly with contemporary experience, rather than with the basically tormalistic issues of picture structure. The work produced under this impetus has influenced photographic thinking throughout the world. This book surveys the major innovative figures in recent Japanese photography and reports on the most significant work being done by younger photographers in Japan today. Alive with visual excitement, the volume presents the distinctive work of fifteen photographers."--Page 4 de la couverture.