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Author : Nina Agabian
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 822 pages
Book Rating : 4.:/5 (43 download)
Download or read book Molecular Strategies of Parasitic Invasion written by Nina Agabian and published by Alan R. Liss. This book was released on 1987 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nina Agabian
Publisher :
ISBN 13 : 9780471629306
Total Pages : 804 pages
Book Rating : 4.6/5 (293 download)
Download or read book Molecular Strategies of Parasitic Invasion written by Nina Agabian and published by . This book was released on 1987-04 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Barbara A. Burleigh
Publisher : Springer Science & Business Media
ISBN 13 : 0387782672
Total Pages : 255 pages
Book Rating : 4.3/5 (877 download)
Download or read book Molecular Mechanisms of Parasite Invasion written by Barbara A. Burleigh and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Author : University of California, Los Angeles
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (497 download)
Download or read book Molecular Strategies of Parasitic Invasion written by University of California, Los Angeles and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780845126417
Total Pages : 775 pages
Book Rating : 4.1/5 (264 download)
Download or read book Molecular Strategies of Parasitic Invasion written by and published by . This book was released on 1987 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780845126417
Total Pages : 775 pages
Book Rating : 4.1/5 (264 download)
Download or read book Molecular Strategies of Parasitic Invasion written by and published by . This book was released on 1986 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michelle Lorine Tonkin
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (895 download)
Download or read book Molecular Strategies for Active Host Cell Invasion by Apicomplexan Parasites written by Michelle Lorine Tonkin and published by . This book was released on 2014 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasites of phylum Apicomplexa cause devastating diseases on a global scale. Toxoplasma gondii, the etiological agent of toxoplasmosis, and Plasmodium falciparum, the most virulent agent of human malaria, have the most substantial effects on human health and are the most widely studied. The success of these parasites is due in part to a sophisticated molecular arsenal that supports a variety of novel biological processes including a unique form of host cell invasion. Accessing the protective environment of the host cell is paramount to parasite survival and is mediated through an active invasion process: the parasite propels itself through a circumferential ring known as the moving junction (MJ) formed between its apical tip and the host cell membrane. The MJ ring is comprised of a parasite surface protein (AMA1) that engages a protein secreted by the parasite into the host cell and presented on the host cell surface (RON2). Thus, through an intriguing mechanism the parasite provides both receptor and ligand to enable host cell invasion. Prior to the studies described herein, the characterization of the AMA1-RON2 association was limited to low-resolution experiments that provided little insight into the functional and architectural details of this crucial binary complex. Towards elucidating the mechanism of AMA1-RON2 dependent invasion, I first structurally characterized T. gondii AMA1 bound to the corresponding binding region of RON2; analysis of the AMA1-RON2 interface along with biophysical data revealed an intimate association likely capable of withstanding the shearing forces generated as the parasite dives through the constricted MJ ring. To investigate the role of the AMA1-RON2 complex across genera, species and life-cycle stages, I next characterized the AMA1-RON2 complex from a distantly related genus within Apicomplexa (Plasmodium) and from a divergent pairing within T. gondii. By combining structural, biophysical and biological data, I was able to generate a detailed model describing the role of AMA1 and RON2 in MJ dependent invasion, which is currently supporting efforts to develop novel vaccines and cross-reactive small molecule therapeutics.
Author : Joseph Marr
Publisher : Elsevier
ISBN 13 : 0080527884
Total Pages : 363 pages
Book Rating : 4.0/5 (85 download)
Download or read book Biochemistry and Molecular Biology of Parasites written by Joseph Marr and published by Elsevier. This book was released on 1995-09-06 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms.Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309045278
Total Pages : 312 pages
Book Rating : 4.0/5 (452 download)
Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Author : Diane E. Griffin
Publisher : Springer Science & Business Media
ISBN 13 : 3540273204
Total Pages : 300 pages
Book Rating : 4.5/5 (42 download)
Download or read book Role of Apoptosis in Infection written by Diane E. Griffin and published by Springer Science & Business Media. This book was released on 2005-08-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: (will follow)
Author : Daniel M. Joel
Publisher : Springer Science & Business Media
ISBN 13 : 3642381464
Total Pages : 519 pages
Book Rating : 4.6/5 (423 download)
Download or read book Parasitic Orobanchaceae written by Daniel M. Joel and published by Springer Science & Business Media. This book was released on 2013-07-01 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written in response to significant recent advances in understanding the mechanisms of parasitism in the Orobanchaceae, and breakthroughs in the control of the parasitic weeds Striga and Orobanche. It consists of 26 contributions by internationally recognized leading scientists. The main book chapters are grouped into two parts: · Part I – The Orobanchaceae and Their Parasitic Mechanisms · Part II – The Weedy Orobanchaceae and Their Control The first part provides cutting-edge information on all key aspects of plant parasitism, such as the structure, development and function of the haustorium; nutrient transfer and the physiology of the parasite-host association; host reaction to parasitic plants; seed production and germination; the strigolactones and host-parasite signaling mechanisms; the parasite genome, phylogenetics, evolution and epigenetics; and ecology. Topics of the second part include: the problem posed by the weedy parasites; population diversity and dynamics; molecular diagnosis of seed banks; and detailed discussion of the various management strategies, including agronomic, chemical and biotechnological approaches, as well as host breeding for resistance, allelopathy and biological control. This book is intended for plant scientists, university lecturers and students, agronomists and weed specialists, breeders and farmers, extension personnel and experts in tropical and subtropical agriculture.
Author : Merlin Willcox
Publisher : CRC Press
ISBN 13 : 0203502329
Total Pages : 464 pages
Book Rating : 4.2/5 (35 download)
Download or read book Traditional Medicinal Plants and Malaria written by Merlin Willcox and published by CRC Press. This book was released on 2004-06-28 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author : Farhat Afrin
Publisher : BoD – Books on Demand
ISBN 13 : 1789841011
Total Pages : 234 pages
Book Rating : 4.7/5 (898 download)
Download or read book Leishmaniases as Re-emerging Diseases written by Farhat Afrin and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
Author : Bhawana Singh
Publisher : BoD – Books on Demand
ISBN 13 : 183968416X
Total Pages : 230 pages
Book Rating : 4.8/5 (396 download)
Download or read book Cell Interaction written by Bhawana Singh and published by BoD – Books on Demand. This book was released on 2021-04-07 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses contemporary ideas on different molecular and immunological aspects of diseases. Different signaling mediators drive the production of messenger molecules that mediate their action, leading to the elicitation/suppression of immune responses. It provides a balanced approach to the study of different molecular phenomena that eventually drive infection outcomes and that can be manipulated for therapeutic benefits.
Author : Steven A. Frank
Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
