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Author : Tobias Pfeiffer
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (958 download)
Download or read book Molecular Simulations of Lipid Bilayers in Interactions with Gold Nanoparticles written by Tobias Pfeiffer and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Katsaras
Publisher : Springer Science & Business Media
ISBN 13 : 366204496X
Total Pages : 304 pages
Book Rating : 4.6/5 (62 download)
Download or read book Lipid Bilayers written by J. Katsaras and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.
Author : Thomas Derrien
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (63 download)
Download or read book Gold Nanoparticle-lipid Bilayer Interactions written by Thomas Derrien and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Fatma N. Kök
Publisher : Springer
ISBN 13 : 3030115968
Total Pages : 306 pages
Book Rating : 4.0/5 (31 download)
Download or read book Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization written by Fatma N. Kök and published by Springer. This book was released on 2019-04-16 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development. Provides fundamental knowledge on biomimetic lipid membranes; Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques; Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques; Describes the integration of biomimetic membranes with current top-notch tools and platforms; Examines applications in medicine, pharmaceutical industry, and environmental monitoring.
Author : Rebecca Notman
Publisher :
ISBN 13 :
Total Pages : 422 pages
Book Rating : 4.:/5 (223 download)
Download or read book Molecular Simulations of the Interaction of Penetration Enhancing Molecules with Lipid Bilayers written by Rebecca Notman and published by . This book was released on 2007 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Olle Edholm
Publisher :
ISBN 13 :
Total Pages : 34 pages
Book Rating : 4.:/5 (185 download)
Download or read book Lipid Bilayer/polypeptide Interactions Studied by Molecular Dynamics Simulation written by Olle Edholm and published by . This book was released on 1985 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Philip Yeagle
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Membranes of Cells written by Philip Yeagle and published by . This book was released on 1993 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this new edition of The Membranes of Cells, all of the chapters have been updated, some have been completely rewritten, and a new chapter on receptors has been added. The book has been designed to provide both the student and researcher with a synthesis of information from a number of scientific disciplines to create a comprehensive view of the structure and function of the membranes of cells. The topics are treated in sufficient depth to provide an entry point to the more detailed literature needed by the researcher. Key Features * Introduces biologists to membrane structure and physical chemistry * Introduces biophysicists to biological membrane function * Provides a comprehensive view of cell membranes to students, either as a necessary background for other specialized disciplines or as an entry into the field of biological membrane research * Clarifies ambiguities in the field
Author : A. Ottova-Leitmannova
Publisher : Gulf Professional Publishing
ISBN 13 : 9780123694539
Total Pages : 348 pages
Book Rating : 4.6/5 (945 download)
Download or read book Advances in Planar Lipid Bilayers and Liposomes written by A. Ottova-Leitmannova and published by Gulf Professional Publishing. This book was released on 2005-09 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The lipid bilayer is central to life, as all living organisms possess a lipid bilayer structure, thereby underlying the lipid bilayer principle of biomembranes. The lipid bilayer principle and its applications are the main theme of this new book series. This new series on bilayer lipid membranes (BLMs and liposomes) include invited chapters on a broad range of topics, from theoretical investigations, specific studies, experimental methods, to practical applications. Written for newcomers, experienced scientists, and those who are not familiar with these specific research areas, the Series covers all aspects of lipid bilayer investigations, both fundamental and applied. * Covers a broad range of topics ranging from theoretical research, specific studies, experimental methods, to practical applications * Authoritative timely reviews by experts in this field * Indispensable source of information for new scientists
Author : Georg Pabst
Publisher : CRC Press
ISBN 13 : 1466507098
Total Pages : 482 pages
Book Rating : 4.4/5 (665 download)
Download or read book Liposomes, Lipid Bilayers and Model Membranes written by Georg Pabst and published by CRC Press. This book was released on 2014-03-04 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evolved from basic studies of the physicochemical properties of amphiphiles to their application in industry and medicine. Written by leading researchers in their fields, this book describes basic and applied research, and serves as a useful reference for both the novice and the expert. Part one covers a range of basic research topics, from theory and computational simulations to some of the most up-to-date experimental research. Topics discussed include soft matter physics of membranes, nonlamellar phases, extraction of molecules by amphiphiles, lipid models for membrane rafts, membrane dynamics, nanodiscs, microemulsions, active membranes, as well as interactions of bilayers with drugs or DNA to treat disease or for gene transfer, respectively. Part two of the book focuses on technological applications of amphiphiles, such as liposome-based nanoparticles for drug delivery, formulation of liposomes for prolonged in vivo circulation and functionalization for medical purposes, novel drug delivery systems for increased drug loading, and the use of tethered membranes for bio-sensing applications. Chapters also describe the use of liposomes in textile dyeing and how lipidic nanoparticles are used by the food industry.
Author : Ayelet Benjamini
Publisher :
ISBN 13 :
Total Pages : 171 pages
Book Rating : 4.:/5 (94 download)
Download or read book Molecular Simulations of Lipid Bilayers and Membrane Helices Interactions written by Ayelet Benjamini and published by . This book was released on 2013 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work we use mesoscopic simulation to investigate the short and medium range interaction of transmembrane helices. First, we develop a coarse-grained model of a generic transmembrane [alpha]-helix. We use the geometry constraints of an [alpha]-helix, along with a set of homogeneous hydrophobic beads. We discuss the reasoning behind this modeling and why various other plausible models have failed in describing the short-range interactions of transmembrane helices. We then show the effect of hydrophobic mismatch on these model helices. The tilt angle of a single helix is affected by its hydrophobic mismatch with the surrounding bilayer. We show that the hydrophobic mismatch, via its effect on the tilt angle, has a crucial effect on the cross angle of two packed transmembrane helices as well. We further show the effect of hydrophobic mismatch on the potential of mean force between the helices as well as on the thickness and tilt angle of the lipids surrounding the helices. We introduce a class of especially long helices, termed super-positive mismatched helices, to which the response of the lipids differs and discuss the origin of this behavior. These coarse-grained simulations are performed using the Dissipative Particle Dynamics (DPD) scheme Performing large time and length scale simulations using this scheme is highly CPU-time consuming. To enhance our simulation capabilities we develop a novel, massively parallel simulation algorithm. We introduce this algorithm and the original concepts we developed for parallelizing the DPD scheme. We show that this novel approach provides up to 30 times speed up on a Graphical Processing Unit (GPU) over the non-parallel CPU version. Finally, we use our parallel algorithm to perform simulation on a large time and length scale system. We investigate the effect of Cholesterol on the bending rigidity of lipid bilayers and show the effect of a phase transition on the bending modulus. Extracting the bending modulus from simulation requires a large system that enables long-range height fluctuations. Using a fast, parallel simulation algorithm for such a task is therefore crucial.
Author : Lev Dykman
Publisher : CRC Press
ISBN 13 : 1351360477
Total Pages : 365 pages
Book Rating : 4.3/5 (513 download)
Download or read book Gold Nanoparticles in Biomedical Applications written by Lev Dykman and published by CRC Press. This book was released on 2017-12-12 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.
Author : M. Patra
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (593 download)
Download or read book Molecular Dynamics Simulations of Lipid Bilayers written by M. Patra and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Corey Evan Musolff
Publisher :
ISBN 13 : 9781303631030
Total Pages : 111 pages
Book Rating : 4.6/5 (31 download)
Download or read book Simulation Study of Lipid Bilayer/nanoparticle Interactions written by Corey Evan Musolff and published by . This book was released on 2013 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kellie Lynne Waterman
Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.:/5 (851 download)
Download or read book Interaction of Gold Nanoparticles with a Supported Lipid Bilayer Using Quartz Crystal Microblance with Dissipation written by Kellie Lynne Waterman and published by . This book was released on 2013 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Matthew Carr
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)
Download or read book Advancing Our Understanding of Lipid Bilayer Interactions written by Matthew Carr and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sidney A. Simon
Publisher : Academic Press
ISBN 13 : 0080925855
Total Pages : 606 pages
Book Rating : 4.0/5 (89 download)
Download or read book Peptide-Lipid Interactions written by Sidney A. Simon and published by Academic Press. This book was released on 2002-11-13 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion. Key Features * world-renowned experts * state-of-the-art experimental methods * monolayers, bilayers, biological membranes * theoretical aspects and computer simulations * rafts * synaptic transmission * membrane fusion * signal transduction
Author : Gabin Fabre
Publisher :
ISBN 13 :
Total Pages : 160 pages
Book Rating : 4.:/5 (866 download)
Download or read book Molecular Dynamic Simulations of the Interaction of Natural Compounds with Lipid Bilayer Membranes written by Gabin Fabre and published by . This book was released on 2012 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the structures of natural molecules, many new derivatives are continuously synthetized to enhance therapeutic. To understand the mechanism of action of these compounds, one of the key steps is the capacity to incorporate/cross lipid bilayer membranes. Molecular dynamics (MD) has recently appeared as a powerful tool to rationalize these interactions at the molecular level. Here we report on two different types of derivatives. The first class concerns antioxidants. One of the most important oxidative processes in the organism is lipid peroxidation in cell membrane. To efficiently stop lipid peroxidation, potential antioxidants have to (i) scavenge free radicals and (ii) incorporate inside the membrane. Lipocarbazole exhibits an efficient antioxidant activity against lipid peroxidation in vitro, which can be correlated to its actual position and orientation inside the membrane. The second class concerns antibacterials. Plantazolicin A exhibits antibacterial activity against Gram+ strains. In order to understand this activity (i) the 3D re-arrangement and (ii) its interaction with bacterial membrane must be fully understood. Using a model of lipid bilayer membrane, the capacity of this compound to form pores is evaluated here.
