Molecular Mechanisms Of Tobacco Induced Diseases

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How Tobacco Smoke Causes Disease

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Molecular Mechanisms of Tobacco-induced Diseases

Author : Xing Li Wang
Publisher : Nova Publishers
ISBN 13 : 9781594545146
Total Pages : 450 pages
Book Rating : 4.5/5 (451 download)

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Book Synopsis Molecular Mechanisms of Tobacco-induced Diseases by : Xing Li Wang

Download or read book Molecular Mechanisms of Tobacco-induced Diseases written by Xing Li Wang and published by Nova Publishers. This book was released on 2005 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite a wealth of epidemiological evidence of the profound ill-effects of smoking on human health, we know surprisingly little about the pathogenic mechanisms by which tobacco smoke actually causes disease. Indeed, to our knowledge this publication represents the first book that is entirely devoted to the molecular and cellular mechanisms of tobacco-induced diseases. Considering that smoking will directly kill 650 million of those people currently alive, the lack of such a book represents a huge gap in the biomedical literature.This new and important book fills this gap.

The Health Consequences of Involuntary Exposure to Tobacco Smoke

Author :
Publisher :
ISBN 13 :
Total Pages : 736 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis The Health Consequences of Involuntary Exposure to Tobacco Smoke by :

Download or read book The Health Consequences of Involuntary Exposure to Tobacco Smoke written by and published by . This book was released on 2006 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Surgeon General's report returns to the topic of the health effects of involuntary exposure to tobacco smoke. The last comprehensive review of this evidence by the Department of Health and Human Services (DHHS) was in the 1986 Surgeon General's report, The Health Consequences of Involuntary Smoking, published 20 years ago this year. This new report updates the evidence of the harmful effects of involuntary exposure to tobacco smoke. This large body of research findings is captured in an accompanying dynamic database that profiles key epidemiologic findings, and allows the evidence on health effects of exposure to tobacco smoke to be synthesized and updated (following the format of the 2004 report, The Health Consequences of Smoking). The database enables users to explore the data and studies supporting the conclusions in the report. The database is available on the Web site of the Centers for Disease Control and Prevention (CDC) at http://www.cdc.gov/tobacco.

Secondhand Smoke Exposure and Cardiovascular Effects

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309138396
Total Pages : 240 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Secondhand Smoke Exposure and Cardiovascular Effects by : Institute of Medicine

Download or read book Secondhand Smoke Exposure and Cardiovascular Effects written by Institute of Medicine and published by National Academies Press. This book was released on 2010-02-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data suggest that exposure to secondhand smoke can result in heart disease in nonsmoking adults. Recently, progress has been made in reducing involuntary exposure to secondhand smoke through legislation banning smoking in workplaces, restaurants, and other public places. The effect of legislation to ban smoking and its effects on the cardiovascular health of nonsmoking adults, however, remains a question. Secondhand Smoke Exposure and Cardiovascular Effects reviews available scientific literature to assess the relationship between secondhand smoke exposure and acute coronary events. The authors, experts in secondhand smoke exposure and toxicology, clinical cardiology, epidemiology, and statistics, find that there is about a 25 to 30 percent increase in the risk of coronary heart disease from exposure to secondhand smoke. Their findings agree with the 2006 Surgeon General's Report conclusion that there are increased risks of coronary heart disease morbidity and mortality among men and women exposed to secondhand smoke. However, the authors note that the evidence for determining the magnitude of the relationship between chronic secondhand smoke exposure and coronary heart disease is not very strong. Public health professionals will rely upon Secondhand Smoke Exposure and Cardiovascular Effects for its survey of critical epidemiological studies on the effects of smoking bans and evidence of links between secondhand smoke exposure and cardiovascular events, as well as its findings and recommendations.

Public Health Consequences of E-Cigarettes

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 030946837X
Total Pages : 775 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Public Health Consequences of E-Cigarettes by : National Academies of Sciences, Engineering, and Medicine

Download or read book Public Health Consequences of E-Cigarettes written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-18 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.

Tobacco and Public Health

Author : Peter Boyle
Publisher :
ISBN 13 : 9780198526872
Total Pages : 840 pages
Book Rating : 4.5/5 (268 download)

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Book Synopsis Tobacco and Public Health by : Peter Boyle

Download or read book Tobacco and Public Health written by Peter Boyle and published by . This book was released on 2004 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively covers the science and policy issues relevant to one of the major public health disasters of modern times. It pulls together the aetiology and burden of the myriad of tobacco related diseases with the successes and failures of tobacco control policies. The book looks at lessons learnt to help set health policy for reducing the burden of tobacco related diseases. The book also deals with the international public health policy issues which bear on control of the problem of tobacco use and which vary between continents. The editors are an international group distinguished in the field of tobacco related diseases, epidemiology, and tobacco control. The contributors are world experts drawn from the various clinical fields. This major reference text gives a unique overview of one of the major public health problems in both the developed and developing world. The book is directed at an international public health and epidemiology audience includng health economists and those interested in tobacco control.

The Health Benefits of Smoking Cessation

Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
ISBN 13 :
Total Pages : 670 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Health Benefits of Smoking Cessation by : United States. Public Health Service. Office of the Surgeon General

Download or read book The Health Benefits of Smoking Cessation written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 1990 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeting Cellular Signalling Pathways in Lung Diseases

Author : Kamal Dua
Publisher : Springer Nature
ISBN 13 : 9813368276
Total Pages : 926 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Targeting Cellular Signalling Pathways in Lung Diseases by : Kamal Dua

Download or read book Targeting Cellular Signalling Pathways in Lung Diseases written by Kamal Dua and published by Springer Nature. This book was released on 2021-07-02 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.

Mechanisms of Resistance to Plant Diseases

Author : R.S. Fraser
Publisher : Springer Science & Business Media
ISBN 13 : 9400951450
Total Pages : 473 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Resistance to Plant Diseases by : R.S. Fraser

Download or read book Mechanisms of Resistance to Plant Diseases written by R.S. Fraser and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant resistance to pathogens is one of the most important strategies of disease control. Knowledge of resistance mechanisms, and of how to exploit them, has made a significant contribution to agricultural productivity. However, the continuous evolution of new variants of pathogen, ana additional control problems posed by new crops and agricultural methods, creates a need for a corresponding increase in our understanding of resistance and ability to utilize it. The study of resistance mechanisms also has attractions from a purely academic point of view. First there is the breadth of the problem, which can be approached at the genetical, molecular, cellular, whole plant or population lev~ls. Often there is the possibility of productive exchange of ideas between different disciplines. Then there is the fact that despite recent advances, many of the mechanisms involved have still to be fully elucidated. Finally, and compared with workers in other areas of biology, the student of resistance is twice blessed in having as his subject the interaction of two or more organisms, with the intriguing problems of recognition, specificity and co-evolution which this raises.

Smoking and Health

Author : United States. Surgeon General's Advisory Committee on Smoking and Health
Publisher :
ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Smoking and Health by : United States. Surgeon General's Advisory Committee on Smoking and Health

Download or read book Smoking and Health written by United States. Surgeon General's Advisory Committee on Smoking and Health and published by . This book was released on 1964 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Smokeless Tobacco and Some Tobacco-specific N-nitrosamines

Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher : World Health Organization
ISBN 13 : 9283212894
Total Pages : 642 pages
Book Rating : 4.2/5 (832 download)

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Book Synopsis Smokeless Tobacco and Some Tobacco-specific N-nitrosamines by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Smokeless Tobacco and Some Tobacco-specific N-nitrosamines written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2007 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eighty-ninth volume of the IARC Monographs is the third and last of a series on tobacco-related agents. Volume 83 reported on the carcinogenicity of tobacco smoke and involuntary smoking (second-hand smoke or environmental tobacco smoke) (IARC 2004a). Volume 85 summarized the evidence on the carcinogenic risk of chewing betel quid with and without tobacco (IARC 2004b). That volume explored the variety of products chewed in South Asia and other parts of the word that contain areca nut in combination with other ingredients, often including tobacco. In this eighty-ninth volume, the carcinogenic risks associated with the use of smokeless tobacco, including chewing tobacco and snuff, are considered in a first monograph. The second monograph reviews some tobacco-specific nitrosamines. These agents were evaluated earlier in Volume 37 of the Monographs (IARC 1985) and information gathered since that time has been summarized and evaluated.

Mechanisms of Carcinogenesis

Author : Elizabeth K. Weisburger
Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Preventing Tobacco Use Among Youth and Young Adults

Author :
Publisher :
ISBN 13 :
Total Pages : 22 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Preventing Tobacco Use Among Youth and Young Adults by :

Download or read book Preventing Tobacco Use Among Youth and Young Adults written by and published by . This book was released on 2012 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: This booklet for schools, medical personnel, and parents contains highlights from the 2012 Surgeon General's report on tobacco use among youth and teens (ages 12 through 17) and young adults (ages 18 through 25). The report details the causes and the consequences of tobacco use among youth and young adults by focusing on the social, environmental, advertising, and marketing influences that encourage youth and young adults to initiate and sustain tobacco use. This is the first time tobacco data on young adults as a discrete population have been explored in detail. The report also highlights successful strategies to prevent young people from using tobacco.

Oral Cancer Detection

Author : Prashanth Panta
Publisher : Springer
ISBN 13 : 3319612557
Total Pages : 315 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Oral Cancer Detection by : Prashanth Panta

Download or read book Oral Cancer Detection written by Prashanth Panta and published by Springer. This book was released on 2019-01-04 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Smoke

Author : Sander L. Gilman
Publisher : Reaktion Books
ISBN 13 : 9781861892003
Total Pages : 416 pages
Book Rating : 4.8/5 (92 download)

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Book Synopsis Smoke by : Sander L. Gilman

Download or read book Smoke written by Sander L. Gilman and published by Reaktion Books. This book was released on 2004 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: People have always smoked, and they probably always will. Every culture in recorded history has smoked something, whether for pleasure or relief, whether as part of an elaborate religious ritual or merely to strike a pose. This is the first truly comprehensive history of smoking, describinbg all of its forms, practices, paraphernalia and materials, in cultures, locations and times throughout the world.

Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309316278
Total Pages : 341 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products by : Institute of Medicine

Download or read book Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products written by Institute of Medicine and published by National Academies Press. This book was released on 2015-07-23 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tobacco use by adolescents and young adults poses serious concerns. Nearly all adults who have ever smoked daily first tried a cigarette before 26 years of age. Current cigarette use among adults is highest among persons aged 21 to 25 years. The parts of the brain most responsible for cognitive and psychosocial maturity continue to develop and change through young adulthood, and adolescent brains are uniquely vulnerable to the effects of nicotine. At the request of the U.S. Food and Drug Administration, Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products considers the likely public health impact of raising the minimum age for purchasing tobacco products. The report reviews the existing literature on tobacco use patterns, developmental biology and psychology, health effects of tobacco use, and the current landscape regarding youth access laws, including minimum age laws and their enforcement. Based on this literature, the report makes conclusions about the likely effect of raising the minimum age to 19, 21, and 25 years on tobacco use initiation. The report also quantifies the accompanying public health outcomes based on findings from two tobacco use simulation models. According to the report, raising the minimum age of legal access to tobacco products, particularly to ages 21 and 25, will lead to substantial reductions in tobacco use, improve the health of Americans across the lifespan, and save lives. Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products will be a valuable reference for federal policy makers and state and local health departments and legislators.

Molecular Epidemiology

Author : Paul A. Schulte
Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.