Molecular Mechanisms Of Spondyloarthropathies

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Molecular Mechanisms of Spondyloarthropathies

Author : Carlos López-Larrea
Publisher : Springer Science & Business Media
ISBN 13 : 1441902988
Total Pages : 338 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Molecular Mechanisms of Spondyloarthropathies by : Carlos López-Larrea

Download or read book Molecular Mechanisms of Spondyloarthropathies written by Carlos López-Larrea and published by Springer Science & Business Media. This book was released on 2009-12-03 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now over ten years since we edited the first edition of HLA-B27 in the Development of Spondyloarthropathies (SpA). It is obvious that over this period an enormous amount of information concerning SpA and HLA-B27 has accumulated, and this has been reflected in the knowledge of molecular mechanism of the spondyloarthropathies. Discussion for such a book took initial form at the outstanding 4th Gent Symposium on SpA in October 2006, but was not formally commissioned by Landes Bioscience until early 2007. Molecular Mechanisms of Spondyloarthropathies aims to synthesize this growing knowledge and present all the current studies concerning the basic research of SpA. Over the last decade, enormous progress has been made in the understanding of the molecular and cellular processes that lead to disease pathology. Recognition of the pathways involved in the pathogenic mechanisms of disease and the potential to target specific immune effector functions have opened the door to a wide range of innovative treatment opportunities for the SpA. Thus, we believe that the understanding of the specific molecular mechanisms involved would help to design highly specific drugs in the future. The contributors are among the best in their field and reflect the state of the art of research and current opinion of rheumatologists and immunologists.

Molecular Pathogenic Mechanisms of Spondyloarthropathies

Author : Luis R. Espinoza
Publisher :
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Molecular Pathogenic Mechanisms of Spondyloarthropathies by : Luis R. Espinoza

Download or read book Molecular Pathogenic Mechanisms of Spondyloarthropathies written by Luis R. Espinoza and published by . This book was released on 1995 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes recent events in the understanding of molecular pathogenic mechanisms in spondyloarthropathies, such as better characterization of clinical syndromes, the association with HLA-B27 mediated genetic factors, and the role of microorganisms, and covers the clinical and therapeutic aspects of this group of diseases as well. Topics include HLA antigens and seronegative spondyloarthropathies, experimental animal models of the diseases, humoral and cellular immune studies, the role of cytokines, and other genetic factors. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR

Ankylosing Spondylitis - Axial Spondyloarthritis

Author : Mohammad Hossein Nicknam
Publisher : Springer Nature
ISBN 13 : 981164733X
Total Pages : 188 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Ankylosing Spondylitis - Axial Spondyloarthritis by : Mohammad Hossein Nicknam

Download or read book Ankylosing Spondylitis - Axial Spondyloarthritis written by Mohammad Hossein Nicknam and published by Springer Nature. This book was released on 2021-10-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ankylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.

Adverse Effects of Vaccines

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309214351
Total Pages : 894 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Adverse Effects of Vaccines by : Institute of Medicine

Download or read book Adverse Effects of Vaccines written by Institute of Medicine and published by National Academies Press. This book was released on 2012-04-26 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Oxford Textbook of Rheumatology

Author : Philip Conaghan
Publisher : Oxford University Press
ISBN 13 : 0199642486
Total Pages : 1553 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Oxford Textbook of Rheumatology by : Philip Conaghan

Download or read book Oxford Textbook of Rheumatology written by Philip Conaghan and published by Oxford University Press. This book was released on 2013-10 with total page 1553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.

Molecular Mimicry: Infection Inducing Autoimmune Disease

Author : Michael B. A. Oldstone
Publisher : Springer Science & Business Media
ISBN 13 : 3540307915
Total Pages : 166 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Molecular Mimicry: Infection Inducing Autoimmune Disease by : Michael B. A. Oldstone

Download or read book Molecular Mimicry: Infection Inducing Autoimmune Disease written by Michael B. A. Oldstone and published by Springer Science & Business Media. This book was released on 2006-01-09 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Text will follow)

Periprosthetic Joint Infection: Practical Management Guide

Author : Parvizi Javad
Publisher : JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN 13 : 9350908255
Total Pages : 432 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Periprosthetic Joint Infection: Practical Management Guide by : Parvizi Javad

Download or read book Periprosthetic Joint Infection: Practical Management Guide written by Parvizi Javad and published by JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.. This book was released on 2013-12-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book Periprosthetic Joint Infection is a portable guide to the practical management of surgical site infections following orthopedic procedures. It designed to help answer clinician's questions regarding the prevention and treatment of periprosthetic infections. It organized for rapid review, featuring evidence reviews, pitfalls, Rothman Institute Current Practices and Controversies. The guide is being included in the course materials for the 29th Annual Current Concepts in Joint Replacement® (CCJR) meeting thanks to a generous educational grant from 3M Health Care.

Activity, Diet and Social Practice

Author : Sarah Schrader
Publisher : Springer
ISBN 13 : 3030025446
Total Pages : 221 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Activity, Diet and Social Practice by : Sarah Schrader

Download or read book Activity, Diet and Social Practice written by Sarah Schrader and published by Springer. This book was released on 2018-12-05 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Day-to-day activities are important in the development of social identities, the establishment of social standing, and the communal understanding of societal rules. This perspective is broadly referred to as practice theory and relates to the power of an overarching social structure and the individual actors that exist within it. Practice theory has made an important contribution to anthropological and archaeological research as these fields are particularly interested in daily life and the importance of these actions. This volume argues that practice theory can also be used in a bioarchaeological context through the examination of human skeletal remains and the archaeological context in which they were excavated. Bioarchaeology offers a unique perspective on these day-to-day experiences—skeletal tissue is constantly undergoing a process of change and, as a living biological system, it can adapt to external forces. Furthermore, bioarchaeological studies are multi-scalar and can examine individuals, groups, or entire populations. Using osteological indicators of activity patterns (entheseal changes, osteoarthritis) and dietary isotopes (carbon, nitrogen) as examples, this book addresses patterns of everyday life in the ancient past. Physical activities and food consumption are actions that are carried out on a daily basis. While bioarchaeology does not have the ability to recreate specific day-to-day activities, we can assess broad trends in everyday life. The volume illustrates these points using examples from the Ancient Nile Valley. Through the examination of over 800 Egyptian and Nubian individuals from five different archaeological sites, the research addresses patterns of everyday life as they relate to social inequality, agency, and practice. Beyond osteological indicators of activity and dietary patterns, this book also discusses additional methods that can be pursed to draw attention to daily life. Lastly, this book also highlights the applicability of and potential contribution that practice theory can make to this area of research.

Spondyloarthropathies, An Issue of Rheumatic Disease Clinics

Author : Juergen Braun
Publisher : Elsevier Health Sciences
ISBN 13 : 1455750603
Total Pages : 236 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Spondyloarthropathies, An Issue of Rheumatic Disease Clinics by : Juergen Braun

Download or read book Spondyloarthropathies, An Issue of Rheumatic Disease Clinics written by Juergen Braun and published by Elsevier Health Sciences. This book was released on 2012-08-28 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by Drs. Juergen Braun and Joachim Sieper, this issue of Rheumatic Disease Clinics comprehensively reviews the state of the art of spondyloarthritis (SpA) diagnosis, prognosis, pathogenesis and genetic insights, and treatment. The worldwide burden of SpA now exceeds that of rheumatoid arthritis. General topics covered include inflammatory back pain, pathophysiology, imaging techniques, and therapeutic strategies.

Imaging of Arthritis and Metabolic Bone Disease E-Book

Author : Barbara N. W. Weissman
Publisher : Elsevier Health Sciences
ISBN 13 : 0323074685
Total Pages : 770 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Imaging of Arthritis and Metabolic Bone Disease E-Book by : Barbara N. W. Weissman

Download or read book Imaging of Arthritis and Metabolic Bone Disease E-Book written by Barbara N. W. Weissman and published by Elsevier Health Sciences. This book was released on 2009-05-09 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get state-of-the-art coverage of the full range of imaging techniques available to assist in the diagnosis and therapeutic management of rheumatic diseases. Written by acknowledged experts in musculoskeletal imaging, this richly illustrated, full-color text presents the latest diagnostic and disease monitoring modalities - MRI, CT, ultrasonography, nuclear medicine, DXA — as well as interventional procedures. You'll find comprehensive coverage of specific rheumatic conditions, including osteoarticular and extraarticular findings. This superb new publication puts you at the forefront of imaging in arthritis and metabolic bone disease — a must have reference for the clinician and imaging specialist. Includes all imaging modalities relevant to rheumatic disease, and applications and contraindications of each, for balanced coverage. Incorporates a user-friendly, consistent full-color format for quick and easy reference. Provides osteoarticular and extra-articular features and findings to show how imaging benefits diagnosis and management of complex rheumatologic conditions. Creates a one-stop shop with comprehensive coverage of imaging for all rheumatic conditions, including metabolic conditions and pediatric disorders. Presents interventional techniques—injections, arthrography, radiofrequency ablation—to create the perfect diagnostic and interventional clinical tool.

Mayo Clinic Internal Medicine Board Review Questions and Answers

Author : Robert D. Ficalora
Publisher : Oxford University Press, USA
ISBN 13 : 0199985871
Total Pages : 164 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Mayo Clinic Internal Medicine Board Review Questions and Answers by : Robert D. Ficalora

Download or read book Mayo Clinic Internal Medicine Board Review Questions and Answers written by Robert D. Ficalora and published by Oxford University Press, USA. This book was released on 2013-08-15 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion volume to: Mayo Clinic internal medicine board review. 10th ed. c2013.

Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases

Author : Mitesh Kumar Dwivedi
Publisher : Springer Nature
ISBN 13 : 9811919461
Total Pages : 680 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases by : Mitesh Kumar Dwivedi

Download or read book Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases written by Mitesh Kumar Dwivedi and published by Springer Nature. This book was released on 2022-08-10 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book in the two volume set provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting into autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focuses on the role of microbiota/probiotics and their distinct mechanisms exerted in management of autoimmune liver, skin, thyroid, rheumatic and myopathic diseases. This could help in better understanding to design therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest immunology, medical microbiology and nutritional sciences will value its contribution. Overall, the book gives a new dimensions and insight in the aspects of microbial role in autoimmune disease pathogenesis and therapeutic aspects.

Clinical and Molecular Advances in Ankylosing Spondylitis

Author : Jacome Bruges-Armas
Publisher : BoD – Books on Demand
ISBN 13 : 9535101374
Total Pages : 182 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical and Molecular Advances in Ankylosing Spondylitis by : Jacome Bruges-Armas

Download or read book Clinical and Molecular Advances in Ankylosing Spondylitis written by Jacome Bruges-Armas and published by BoD – Books on Demand. This book was released on 2012-02-22 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first section of the book entitled Clinical and Molecular Advances in Ankylosing Spondylitis is a review of the clinical manifestations of Ankylosing Spondylitis (AS) and Spondyloarthritis (SpA). The book includes chapters on Bone Mineral Density measurements, two chapters on the temporomandibular joints, axial fractures, clinical manifestations, diagnosis, and treatment. Molecular genetics and immune response are analyzed in the second section of the book; information on HLA-B*27, other MHC genes and the immune response of AS patients to bacteria is reviewed and updated. Two chapters are dedicated to recent information on non-MHC genes in AS susceptibility, and to new data on disease pathways generated from gene expression studies on peripheral blood.

Palaeopathology

Author : Tony Waldron
Publisher : Cambridge University Press
ISBN 13 : 1139474006
Total Pages : 542 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Palaeopathology by : Tony Waldron

Download or read book Palaeopathology written by Tony Waldron and published by Cambridge University Press. This book was released on 2008-10-20 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Palaeopathology is designed to help bone specialists with diagnosis of diseases in skeletal assemblages. It suggests an innovative method of arriving at a diagnosis in the skeleton by applying what are referred to as 'operational definitions'. The aim is to ensure that all those who study bones will use the same criteria for diagnosing disease, which will enable valid comparisons to be made between studies. This book is based on modern clinical knowledge and provides background information so that those who read it will understand the natural history of bone diseases, and this will enable them to draw reliable conclusions from their observations. Details of bone metabolism and the fundamentals of basic pathology are also provided, as well as a comprehensive and up-to-date bibliography. A short chapter on epidemiology provides information on how best to analyze and present the results of a study of human remains.

Idiotypes in Medicine: Autoimmunity, Infection and Cancer

Author : R.C. Kennedy
Publisher : Elsevier
ISBN 13 : 0080534430
Total Pages : 557 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Idiotypes in Medicine: Autoimmunity, Infection and Cancer by : R.C. Kennedy

Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.

Postgraduate Orthopaedics

Author : Paul A. Banaszkiewicz
Publisher : Cambridge University Press
ISBN 13 : 1107627362
Total Pages : 301 pages
Book Rating : 4.1/5 (76 download)

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Book Synopsis Postgraduate Orthopaedics by : Paul A. Banaszkiewicz

Download or read book Postgraduate Orthopaedics written by Paul A. Banaszkiewicz and published by Cambridge University Press. This book was released on 2012-08-16 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).

Encyclopedia of Molecular Mechanisms of Disease

Author : Florian Lang
Publisher : Springer Science & Business Media
ISBN 13 : 3540671366
Total Pages : 2348 pages
Book Rating : 4.5/5 (46 download)

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Book Synopsis Encyclopedia of Molecular Mechanisms of Disease by : Florian Lang

Download or read book Encyclopedia of Molecular Mechanisms of Disease written by Florian Lang and published by Springer Science & Business Media. This book was released on 2009-03-19 with total page 2348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedia supplies the reader with concise information on the molecular pathophysiology of disease. Entries include defined diseases (such as Parkinson's disease) as well as pathophysiological entities (such as tremor). The 1,200 essays are brilliantly structured to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by up to five references. Individual entries are written by leading experts in the respective area of research to ensure state-of-the-art descriptions of the mechanisms involved. It is an invaluable companion for clinicians and scientists in all medical disciplines.