Molecular Mechanisms of Signalling and Membrane Transport

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Publisher : Springer Science & Business Media
ISBN 13 : 3642607993
Total Pages : 340 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Molecular Mechanisms of Signalling and Membrane Transport by : Karel W.A. Wirtz

Download or read book Molecular Mechanisms of Signalling and Membrane Transport written by Karel W.A. Wirtz and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Study Institute on Molecular Mechanisms of Signalling and Targeting, held on the Island of Spetsai, Greece, August 18-30, 1996

Molecular Biology of the Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cellular Signal Processing

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Publisher : Garland Science
ISBN 13 : 1351677225
Total Pages : 640 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Cellular Signal Processing by : Friedrich Marks

Download or read book Cellular Signal Processing written by Friedrich Marks and published by Garland Science. This book was released on 2017-05-17 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Molecular Mechanisms of Membrane Traffic

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Publisher : Springer Science & Business Media
ISBN 13 : 3662029286
Total Pages : 417 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Molecular Mechanisms of Membrane Traffic by : D. James Morre

Download or read book Molecular Mechanisms of Membrane Traffic written by D. James Morre and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of membrane traffic in reconstituted cell-free systems has generated an unprecedented amount of new information on the biochemistry, molecular biology and genetics of membrane-based molecular events that underly normal and abnormal cellular function. Many of the individual steps have now been isolated and dissected in simple systems that permit detailed molecular analyses of transport mechanisms and their regulation. Reconstituted events of intercompartment transport include inter-membrane recognition, and controlled membrane fusion-fission reactions. Among the many advances is the growi ng awareness of a remarkabl e evolutionary conservation of many of the components involved in the many steps of membrane traffic, this realization has accelerated greatly the pace of progress in the field. This book provides a collection of participant contributions from the 1992 Summer Research Conference, "Mol ecul ar Mechani sms of Membrane Traffi c, " jointly sponsored with NATO by the American Society of Cell Biology. The conference was held May 9-13, at the Airlie Conference Center in the Virginia countryside, near Warrenton. The conference was attended by 158 scientists. A unique feature was the high proportion of young scientists among the participants. Approximately 65% were students, postdoctoral fe 11 ows and young investigators. Each attendee contri buted to the conference with either a pl atform or poster presentation.

Molecular Mechanisms Controlling Transmembrane Transport

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540218371
Total Pages : 432 pages
Book Rating : 4.2/5 (183 download)

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Book Synopsis Molecular Mechanisms Controlling Transmembrane Transport by : Eckhard Boles

Download or read book Molecular Mechanisms Controlling Transmembrane Transport written by Eckhard Boles and published by Springer Science & Business Media. This book was released on 2004-06-16 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.

Molecular Mechanisms of Signal Transduction

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Publisher : IOS Press
ISBN 13 : 9781586030162
Total Pages : 298 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Molecular Mechanisms of Signal Transduction by : Johannes Lukas Bos

Download or read book Molecular Mechanisms of Signal Transduction written by Johannes Lukas Bos and published by IOS Press. This book was released on 2000 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains overviews of topics that have been discussed. It includes contributions from leading experts in the field on small GTPases, protein kinesis, receptors and transcription factors. A particular focus was the influence of oxygen radicals on signalling processes. It also contains the contributions of scientists early in their career, who have made an excellent contribution to the institute.

Molecular Mechanisms of Water Transport Across Biological Membranes

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Publisher : Gulf Professional Publishing
ISBN 13 : 9780123646194
Total Pages : 472 pages
Book Rating : 4.6/5 (461 download)

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Book Synopsis Molecular Mechanisms of Water Transport Across Biological Membranes by : Wilfred D. Stein

Download or read book Molecular Mechanisms of Water Transport Across Biological Membranes written by Wilfred D. Stein and published by Gulf Professional Publishing. This book was released on 2002-04-02 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume looks at water movements from a wide range of levels. It examines how water interacts with the major components of the cell, including proteins and lipids. It discusses how water moves across cell membranes by diffusion, how it is chanelled across these membranes or, in certain cases, pumped across, and how water movements are controlled. This book demonstrates how water and ion movements are closely linked in order to provide a better understanding of their behavior. *Essential Physical chemistry of water at biological interfaces *Up-to-date reviews of water behavior in cells *Water in integrated systems *Current information on water channels across membranes

Membrane Transport in Plants and Fungi

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Membrane Transport in Plants and Fungi by : Society for Experimental Biology (Great Britain)

Download or read book Membrane Transport in Plants and Fungi written by Society for Experimental Biology (Great Britain) and published by . This book was released on 1994 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Receptors, Membrane Transport and Signal Transduction

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Publisher : Springer Science & Business Media
ISBN 13 : 3642742009
Total Pages : 398 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Receptors, Membrane Transport and Signal Transduction by : A.E. Evangelopoulos

Download or read book Receptors, Membrane Transport and Signal Transduction written by A.E. Evangelopoulos and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NATO Advanced study Institute on "Receptors, Membrane Trans port and Signal Transduction", was held on the Island of Spet sai, Greece, from August 16-27, 1988, in order to consider re cent developments in membrane receptor research, membrane trans port and signal transduction mechanisms. These topics were put in the larger context of current knowledge on the structure and function of membranes; connections between different fields of research were established by in-depth dis cussions of energy transduction and transport mechanisms. The general principles of regulation by signal transduction and protein phosphorylation/dephosphorylation were presented in the context of specific cellular processes. Discussions included al so the role of protein tyrosine kinases which are structurally related to oncogene products and, therefore, implicated in va rious aspects of cell development and transformation. This book presents the content of the major lectures and a se lection of the most relevant posters presented during the course of the Institute. The book is intended to make the proceedings of the Institute accessible to a larger audience and to offer a comprehensive account of those topics on receptors, membrane transport and signal transduction that were discussed extensive ly during the course of the Institute. February 1989 The Editors CONTENTS I. G-PROTEINS, ADENYLATE CYCLASE AND PROTEIN PHOSPHORYLATION Selective regulation of G proteins by Cell surface receptors ......... .

Regulatory Mechanisms of Intracellular Membrane Transport

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540223023
Total Pages : 228 pages
Book Rating : 4.2/5 (23 download)

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Book Synopsis Regulatory Mechanisms of Intracellular Membrane Transport by : Sirkka Keränen

Download or read book Regulatory Mechanisms of Intracellular Membrane Transport written by Sirkka Keränen and published by Springer Science & Business Media. This book was released on 2004-08-27 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on such mechanisms and processes. The contents discusses the role of coat proteins, tethering complexes, small rab GTPases, Sec1-family proteins and SNARE molecule phosphorylation in exocytosis, endocytosis and membrane fusion. In addition, the role of lipids in vesicle formation and membrane fusion, and some specialized cell biological denovo membrane generation processes are discussed.

Molecular Biology of Membrane Transport Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 1461311438
Total Pages : 687 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Molecular Biology of Membrane Transport Disorders by : Thomas E. Andreoli

Download or read book Molecular Biology of Membrane Transport Disorders written by Thomas E. Andreoli and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.

Molecular Mechanisms of Transcellular Signaling

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Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Molecular Mechanisms of Transcellular Signaling by : Jean-Paul Thiery

Download or read book Molecular Mechanisms of Transcellular Signaling written by Jean-Paul Thiery and published by . This book was released on 1999 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Lipid and Protein Traffic

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Publisher : Springer Science & Business Media
ISBN 13 : 3642514634
Total Pages : 364 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Lipid and Protein Traffic by : Jos A.F. Op den Kamp

Download or read book Lipid and Protein Traffic written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The meeting on "Molecular Mechanisms of Lipid and Protein Traffic", sponsored by NATO Scientific Affairs Division as an Advanced Study Institute and by the Federation of European Biochemical Societies as a Lecture Course was held in Cargese, France, in June 1997. The program included introductory lectures, specialized up-to-date contributions, poster sessions, tutorials and workshops. Emphasis was laid on the new developments in the field of membrane dynamics, in particular on the insertion and translocation of proteins; on intracellular protein, lipid and membrane traffic and sorting and on the mutual interactions between the various events occurring during membrane biogenesis. Mitochondrial biogenesis, chloroplast assembly and the insertion of proteins into peroxisomes were highlighted. Much progress in these research areas has been made in recent years and the ASI provided an excellent opportunity to illustrate this progress in comparison with previous meetings on a similar topic. Not only graduate students and postdocs took advantage from this program but also experienced scientists were given the opportunity to obtain a complete overview of recent progress and the remodeling of ideas and concepts.

Molecular Mechanisms of Water Transport

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Author :
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 192 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Mechanisms of Water Transport by : Thomas Zeuthen

Download or read book Molecular Mechanisms of Water Transport written by Thomas Zeuthen and published by Landes Bioscience. This book was released on 1996 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein, Lipid and Membrane Traffic

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Publisher : IOS Press
ISBN 13 : 9781586030087
Total Pages : 290 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Protein, Lipid and Membrane Traffic by : North Atlantic Treaty Organization. Scientific Affairs Division

Download or read book Protein, Lipid and Membrane Traffic written by North Atlantic Treaty Organization. Scientific Affairs Division and published by IOS Press. This book was released on 2000 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text concentrates on the following specific topics: the dynamic character of lipids and proteins in biological membranes; the existence of specific domains in membranes including their visualisation; the molecular mechanisms of intracellular transport of membrane constituents and the involvement of lipid-protein interactions in these processes; protein assembly; structure and folding and transport through membranes; and the intracellular sorting and targeting of individual membrane components as well as different organelles."

Molecular Mechanisms Controlling Transmembrane Transport

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Publisher : Springer
ISBN 13 : 9783662308202
Total Pages : 407 pages
Book Rating : 4.3/5 (82 download)

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Book Synopsis Molecular Mechanisms Controlling Transmembrane Transport by : Eckhard Boles

Download or read book Molecular Mechanisms Controlling Transmembrane Transport written by Eckhard Boles and published by Springer. This book was released on 2014-08-23 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living cells are strictly separated from their surroundings by a membranous lipid bilayer. Into these membranes a variety of transport proteins are embedded that ensure the uptake and secretion of various molecules and ions. In order to respond properly to a changing nutrient supply or demand, as well as to external stress factors, cells must be able to adapt both amount and activity of the corresponding transporters. This book provides readers with state-of-the-art knowledge on the various regulatory mechanisms that control transmembrane transporter expression, activity and their subcellular localisation.

Capturing Atomic-level Mechanisms for Membrane Transport and Signaling with Biomolecular Simulation

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Capturing Atomic-level Mechanisms for Membrane Transport and Signaling with Biomolecular Simulation by : Naomi Rose Latorraca

Download or read book Capturing Atomic-level Mechanisms for Membrane Transport and Signaling with Biomolecular Simulation written by Naomi Rose Latorraca and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins embedded in cell membranes translate a broad range of environmental cues--including the presence of nutrients, drugs, ions and photons--into molecular signals to induce appropriate cellular responses. Membrane proteins thus represent a control panel of the cell and constitute key drug targets for the treatment of a range of diseases. Designing medications to effectively modulate these proteins, however, remains exceedingly challenging and would benefit dramatically from an atomic-level understanding of how these proteins work. Here, I have used molecular dynamics (MD) simulations--which describe how every atom in a biological system evolves with high resolution in space and time--to reveal functional mechanisms for transporters and receptors, two essential classes of membrane proteins. This approach allowed us to address several long-standing questions in molecular biology. For example, we captured the complete process of substrate translocation through an alternating-access membrane transporter. These simulations, which revealed structural rearrangements in the protein that control substrate passage across the membrane as well as the driving forces underlying those transitions, suggest a structural foundation for the design of highly specific and more efficacious transporter-targeted medications. We also revealed the mechanism by which G protein--coupled receptors stimulate arrestins, intracellular regulators of cell signaling. By identifying atomic-level interactions at the GPCR--arrestin interface that drive arrestin activation, we provide a framework for designing drugs that could selectively block or stimulate arrestin signaling, thereby reducing unwanted side effects. In each study, we worked closely with our experimental collaborators to validate predictions derived from our computational results.