Molecular Mechanisms Involved In Human Obesity

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Cellular and Biochemical Mechanisms of Obesity

Author : Paramjit S. Tappia
Publisher : Springer Nature
ISBN 13 : 3030847632
Total Pages : 420 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Cellular and Biochemical Mechanisms of Obesity by : Paramjit S. Tappia

Download or read book Cellular and Biochemical Mechanisms of Obesity written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2021-12-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.

ABC of Obesity

Author : Naveed Sattar
Publisher : John Wiley & Sons
ISBN 13 : 1444312707
Total Pages : 64 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis ABC of Obesity by : Naveed Sattar

Download or read book ABC of Obesity written by Naveed Sattar and published by John Wiley & Sons. This book was released on 2009-04-08 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a hugely expensive and increasing problem worldwide,leading to disability, reproductive problems, depression andaccelerated metabolic and vascular diseases in a large proportionof men, women and children. The ABC of Obesity is a newguide which will aid its effective management, addressing issuessuch as dieting, exercise, self esteem, drug treatment and surgery.Recent evidence is used to highlight frequent problems, successfultreatment options, and the most common causes. Written by leading experts, this is a widely accessible text andan indispensable guide for all general practitioners, juniordoctors, nurses, and other healthcare professionals who areinvolved in the treatment and research of this commoncondition.

The Genetics of Obesity

Author : Claude Bouchard
Publisher : CRC Press
ISBN 13 : 9780849348808
Total Pages : 262 pages
Book Rating : 4.3/5 (488 download)

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Book Synopsis The Genetics of Obesity by : Claude Bouchard

Download or read book The Genetics of Obesity written by Claude Bouchard and published by CRC Press. This book was released on 1994-03-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.

Weight Management

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309089964
Total Pages : 277 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Weight Management by : Institute of Medicine

Download or read book Weight Management written by Institute of Medicine and published by National Academies Press. This book was released on 2003-12-01 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purpose of fitness and body composition standards in the U.S. Armed Forces has always been to select individuals best suited to the physical demands of military service, based on the assumption that proper body weight and composition supports good health, physical fitness, and appropriate military appearance. The current epidemic of overweight and obesity in the United States affects the military services. The pool of available recruits is reduced because of failure to meet body composition standards for entry into the services and a high percentage of individuals exceeding military weight-for-height standards at the time of entry into the service leave the military before completing their term of enlistment. To aid in developing strategies for prevention and remediation of overweight in military personnel, the U.S. Army Medical Research and Materiel Command requested the Committee on Military Nutrition Research to review the scientific evidence for: factors that influence body weight, optimal components of a weight loss and weight maintenance program, and the role of gender, age, and ethnicity in weight management.

Obesity and Diabetes

Author : Joel Faintuch
Publisher : Springer Nature
ISBN 13 : 3030533700
Total Pages : 994 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Obesity and Diabetes by : Joel Faintuch

Download or read book Obesity and Diabetes written by Joel Faintuch and published by Springer Nature. This book was released on 2020-12-14 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Obesity and Lipotoxicity

Author : Ayse Basak Engin
Publisher : Springer
ISBN 13 : 331948382X
Total Pages : 618 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Obesity and Lipotoxicity by : Ayse Basak Engin

Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.

Genes and Obesity

Author :
Publisher : Academic Press
ISBN 13 : 0080962033
Total Pages : 417 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Genes and Obesity by :

Download or read book Genes and Obesity written by and published by Academic Press. This book was released on 2010-12-17 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of genes have been identified that are associated with an increased body mass index (BMI), the standard measurement of obesity. By analyzing these genes, researchers hope to gain a better understanding of what causes obesity and develop ways to tackle the problem. The study of genes and obesity could lead to new treatments. Genes and Obesity reviews the latest developments in the field. - This series provides a forum for discussion of new discoveries, approaches, and ideas - Contributions from leading scholars and industry experts - Reference guide for researchers involved in molecular biology and related fields

Weight Control and Physical Activity

Author : Harri Vainio
Publisher : IARC
ISBN 13 : 9789283230069
Total Pages : 346 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Weight Control and Physical Activity by : Harri Vainio

Download or read book Weight Control and Physical Activity written by Harri Vainio and published by IARC. This book was released on 2002 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Obesity and Diabetes

Author : Anthony H. Barnett
Publisher : John Wiley & Sons
ISBN 13 : 0470011092
Total Pages : 324 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Obesity and Diabetes by : Anthony H. Barnett

Download or read book Obesity and Diabetes written by Anthony H. Barnett and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases

Download Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases PDF Online Free

Author : Maricela Rodriguez Cruz
Publisher : Bentham Science Publishers
ISBN 13 : 1608051773
Total Pages : 103 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases by : Maricela Rodriguez Cruz

Download or read book Latest Findings Of Omega-3 Long Chain Polyunsaturated Fatty Acids: From Molecular Mechanisms To New Applications In Health And Diseases written by Maricela Rodriguez Cruz and published by Bentham Science Publishers. This book was released on 2011 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This E-book covers the main aspects about the benefits of omega-3 long chain polyunsaturated fatty acids (LC-PUFAs) to human health. The knowledge of physiological effects of LC-PUFAs at different levels is constantly expanding. Topics covered over 10 chapters thoroughly detail the role of omega-3 LCPUFAs in nutrition (gene regulation) and disease (clinical applications); information about food sources and recent intake recommendations is also explained. This book also discusses current data concerning the role of LC-PUFAs during pregnancy and lactation, in cognitive function, immune response.

Chronic Inflammation

Author : Masayuki Miyasaka
Publisher : Springer
ISBN 13 : 4431560688
Total Pages : 679 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Chronic Inflammation by : Masayuki Miyasaka

Download or read book Chronic Inflammation written by Masayuki Miyasaka and published by Springer. This book was released on 2016-11-01 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with the most up-to-date information on cutting-edge research concerning chronic inflammation. We now know that when inflammation becomes chronic, it acts as a strong disease-promoting factor in a variety of disorders including arteriosclerosis, obesity, cancer, and Alzheimer disease. Chronic inflammation is hence called as the “silent killer”; it upsets the body’s homeostatic mechanism insidiously. In spite of these developments, we know very little about the mechanism underlying chronic inflammation. Particularly, we do not know precisely what induces chronic inflammation or what promotes its prolongation in a spatiotemporal framework. Neither do we have clear knowledge about how chronic inflammation destroys various tissues or how it predisposes individuals to many different diseases. To make the situation worse, we have no effective treatment against chronic inflammation. Since 2010, two major research programs (CREST and PRESTO) aimed at clarifying the mechanisms underlying chronic inflammation were launched in Japan, and investigators of different research areas with a brilliant track record were selected by their research proposals. Subsequently they have made their best efforts to answer the conundrum concerning chronic inflammation. This book is a compendium of such research efforts. In each chapter, the CREST- or PRESTO-funded researchers summarize their original work concerning mechanisms of induction, progression, or resolution underlying chronic inflammation. The most emphasized characteristic is the molecular aspect of chronic inflammation. The book thus presents the most recent progress made in the molecular understanding of chronic inflammation.

Obesity and Diabetes

Author : Christos S. Mantzoros
Publisher : Springer Science & Business Media
ISBN 13 : 1588295389
Total Pages : 553 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Obesity and Diabetes by : Christos S. Mantzoros

Download or read book Obesity and Diabetes written by Christos S. Mantzoros and published by Springer Science & Business Media. This book was released on 2006-01-25 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.

Molecular Mechanisms Underpinning the Development of Obesity

Author : Clévio Nóbrega
Publisher : Springer
ISBN 13 : 3319127667
Total Pages : 200 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Molecular Mechanisms Underpinning the Development of Obesity by : Clévio Nóbrega

Download or read book Molecular Mechanisms Underpinning the Development of Obesity written by Clévio Nóbrega and published by Springer. This book was released on 2014-12-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.

Adipose Tissue in Health and Disease

Author : Todd Leff
Publisher : John Wiley & Sons
ISBN 13 : 9783527629534
Total Pages : 530 pages
Book Rating : 4.6/5 (295 download)

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Book Synopsis Adipose Tissue in Health and Disease by : Todd Leff

Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome

Author : Helmut Sies
Publisher : CRC Press
ISBN 13 : 142004379X
Total Pages : 346 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome by : Helmut Sies

Download or read book Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome written by Helmut Sies and published by CRC Press. This book was released on 2007-07-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central

Gut Hormones

Author : Stephen Robert Bloom
Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Gut Hormones by : Stephen Robert Bloom

Download or read book Gut Hormones written by Stephen Robert Bloom and published by . This book was released on 1981 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polycystic Ovary Syndrome

Author : Andrea Dunaif
Publisher : Springer Science & Business Media
ISBN 13 : 1597451088
Total Pages : 361 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Polycystic Ovary Syndrome by : Andrea Dunaif

Download or read book Polycystic Ovary Syndrome written by Andrea Dunaif and published by Springer Science & Business Media. This book was released on 2008-01-12 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.