Molecular Genetics Of Sex Determination

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Molecular Genetics of Sex Determination

Author : Stephen S. Wachtel
Publisher : Academic Press
ISBN 13 : 1483295583
Total Pages : 537 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Genetics of Sex Determination by : Stephen S. Wachtel

Download or read book Molecular Genetics of Sex Determination written by Stephen S. Wachtel and published by Academic Press. This book was released on 2014-07-23 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students. Reviews the genetics of sex determination in 19 up-to-date chapters Features research on sex chromosomes and sex-determining genes Includes abnormalities of sex determination and clinical genetics Written by scientists who pioneered work in this field

The Genetics and Biology of Sex Determination

Author : Derek J. Chadwick
Publisher : John Wiley & Sons
ISBN 13 : 9780470843468
Total Pages : 286 pages
Book Rating : 4.8/5 (434 download)

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Book Synopsis The Genetics and Biology of Sex Determination by : Derek J. Chadwick

Download or read book The Genetics and Biology of Sex Determination written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2002-04-26 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.

Genetics of Sex Determination

Author : R.S. Verma
Publisher : Elsevier
ISBN 13 : 9780080526171
Total Pages : 368 pages
Book Rating : 4.5/5 (261 download)

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Book Synopsis Genetics of Sex Determination by : R.S. Verma

Download or read book Genetics of Sex Determination written by R.S. Verma and published by Elsevier. This book was released on 1996-04-23 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Genetical Theory of Natural Selection by R.A. Fisher (1930) dictated that sexual dimorphisms may depend upon a single medelian factor. This could be true for some species but his suggestion could not take off the ground as gender in Drosophila is determined by the number of X chromosomes. Technical advances in molecular biology have revived the initial thinking of Fisher and dictate that TDF or SRY genes in humans or Tdy in mice are sex determining genes. The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, are quite bewildering traits that have caused much amazement concerning the pairing mechanism(s) of the pseudoautosomal regions of human X and Y chromosomes at meiosis. These findings have opened new avenues to explore further the genetic basis of sex determination at the single gene level. The aim of the fourth volume, titled Genetics of Sex Determination is to reflect on the latest advances and future investigative directions, encompassing 10 chapters. Commissioned several distinguished scientists, all pre-eminent authorities in each field to shed their thoughts concisely but epitomise their chapters with an extended bibliography. Obviously, during the past 60 years, the metoric advances are voluminous and to cover every account of genes, chromosomes, and sex in a single volume format would be a herculean task. Therefore, a few specific topics are chosen, which may be of great interest to scientists and clinicians. The seasoned scientists who love to inquire about the role of genes in sex determination should find the original work of these notable contributors very enlightening. This volume is intended for advanced students who want to keep abreast as well as for those who indulge in the search for genes of sex determination.

Exploring the Biological Contributions to Human Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309132975
Total Pages : 287 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exploring the Biological Contributions to Human Health by : Institute of Medicine

Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

The Genetics and Biology of Sex Determination (Novartis Foundation Symposia Book 244)

Author : Derek'' J. Chadwic'k
Publisher :
ISBN 13 :
Total Pages : 275 pages
Book Rating : 4.7/5 (459 download)

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Book Synopsis The Genetics and Biology of Sex Determination (Novartis Foundation Symposia Book 244) by : Derek'' J. Chadwic'k

Download or read book The Genetics and Biology of Sex Determination (Novartis Foundation Symposia Book 244) written by Derek'' J. Chadwic'k and published by . This book was released on 2021-04-29 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms.By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.

The Evolution of Sex Determination

Author : Leo W. Beukeboom
Publisher : Oxford University Press, USA
ISBN 13 : 0199657149
Total Pages : 243 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis The Evolution of Sex Determination by : Leo W. Beukeboom

Download or read book The Evolution of Sex Determination written by Leo W. Beukeboom and published by Oxford University Press, USA. This book was released on 2014 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: temperature) or social variables (e.g.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular-Genetic Mechanisms of Sex Determination in Animals

Author : Aleksandr F. Smirnov
Publisher : Scientific Research Publishing, Inc. USA
ISBN 13 : 1618963902
Total Pages : 118 pages
Book Rating : 4.6/5 (189 download)

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Book Synopsis Molecular-Genetic Mechanisms of Sex Determination in Animals by : Aleksandr F. Smirnov

Download or read book Molecular-Genetic Mechanisms of Sex Determination in Animals written by Aleksandr F. Smirnov and published by Scientific Research Publishing, Inc. USA. This book was released on with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gender (sex) is a set of morphological and physiological characteristics of the organism underlying sexual reproduction, the essence of which is reduced to fertilization, i.e. the fusion of male and female gametes (gametes) zygote, which develops into a new organism.Sexual reproduction of a species is considered as one of the mechanisms of its homeostasis. Thanks to this mechanism, numerous species have an evolutionary advantage. In the book, two authors will discuss the types of genetic sex determination and differentiation, mostly in multicellular animal organisms. Sex determination is both genetic and environmental process, the sex of an individual being established through an alternative physiological solution. There are two main postulated mechanisms of sex determination: genetic (GSD, Genetical Sex Determination) and environmental (ESD, Environmental Sex Determination).

Genes and Mechanisms in Vertebrate Sex Determination

Author : Gerd Scherer
Publisher : Birkhäuser
ISBN 13 : 3034877811
Total Pages : 210 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Genes and Mechanisms in Vertebrate Sex Determination by : Gerd Scherer

Download or read book Genes and Mechanisms in Vertebrate Sex Determination written by Gerd Scherer and published by Birkhäuser. This book was released on 2013-04-17 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.

Sex Chromosomes and Sex Determination in Vertebrates

Author : Alberto J. Solari
Publisher : CRC Press
ISBN 13 : 9780849345715
Total Pages : 340 pages
Book Rating : 4.3/5 (457 download)

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Book Synopsis Sex Chromosomes and Sex Determination in Vertebrates by : Alberto J. Solari

Download or read book Sex Chromosomes and Sex Determination in Vertebrates written by Alberto J. Solari and published by CRC Press. This book was released on 1993-10-22 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cloning of the SRY gene and the attainment of XX mice transgenic for the Sry gene opened a new era in research on sex determination. This book surveys current knowledge of sex chromosomes and sex determination in all vertebrate classes, relying on the restriction of genetic recombination in sex chromosomes as the unifying concept of this subject. The book's interdisciplinary approach integrates contributions from the fields of cytogenetics, molecular biology, developmental biology, and evolutionary genetics. A detailed treatment of the meiotic behavior of sex chromosomes is featured, and the entire text is supplemented by numerous schemes, drawings, and electron micrographs. The book will be valuable to general cytogeneticists, vertebrate zoologists, and veterinarian and medical practitioners interested in the foundations of sex determination and the current knowledge of sex chromosomes. It will also interest students in advanced undergraduate and graduate courses in these areas.

Sex Chromosomes and Sex-determining Genes

Author : Ken Reed
Publisher : Harwood Academic Pub
ISBN 13 : 9783718652761
Total Pages : 410 pages
Book Rating : 4.6/5 (527 download)

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Book Synopsis Sex Chromosomes and Sex-determining Genes by : Ken Reed

Download or read book Sex Chromosomes and Sex-determining Genes written by Ken Reed and published by Harwood Academic Pub. This book was released on 1993 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis throughout is on the genetic determinants of sex. The major issues addressed are sex chromosome differentiation, X-chromosome inactivation and the role of the Y-linked gene SRY in gonad differentiation. A combination of authoritative reviews and original articles drawn from experiment and observation on a variety of systems is complemented by the editors thoughtful introductions. 'Sex is compelling in its benefits, elegant in its conception, startling in its manifestations.' So begins this timely and thoughtful review of the most fascinating property of life. For centuries we have puzzled over the differences between males and females but only recently have we begun to understand the genetic switches that trigger the dramatic differences in form and function between the sexes. This book brings together contributions from many of the scientists who have been responsible for recent stunning advances in our understanding of sex determination and sexual differentiation. The editors have

Sex Determination, Differentiation and Intersexuality in Placental Mammals

Author : R. H. F. Hunter
Publisher : Cambridge University Press
ISBN 13 : 9780521462181
Total Pages : 360 pages
Book Rating : 4.4/5 (621 download)

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Book Synopsis Sex Determination, Differentiation and Intersexuality in Placental Mammals by : R. H. F. Hunter

Download or read book Sex Determination, Differentiation and Intersexuality in Placental Mammals written by R. H. F. Hunter and published by Cambridge University Press. This book was released on 1995-03-09 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do males become male and females become female? And what are the consequences if the decision is not incisive? Drawing upon interests in animal genetics and molecular biology, the author endeavours to answer these difficult yet fascinating questions. Originally published in 1995, this book describes the genetic determination of sex and examines how sexual organs are differentiated. Using examples of intersexuality, chimaeras and asymmetries, the book describes the underlying molecular basis of sex determination and sexual differentiation, and focuses on the critical role of the rate of embryonic development in these vital processes. Male precocity is a recurrent theme, as is the involvement of Sertoli cells and their secretion of anti-Müllerian hormone. An invaluable book for reproductive physiologists, geneticists and developmental biologists whose interests may extend from animal science through veterinary medicine to human clinical medicine.

Human Chromosomes

Author : Orlando J. Miller
Publisher : Springer Science & Business Media
ISBN 13 : 1461301394
Total Pages : 508 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Human Chromosomes by : Orlando J. Miller

Download or read book Human Chromosomes written by Orlando J. Miller and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth edition of this well-known text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes. This new edition continues to cover both basic and up-to-date material on normal and defective chromosomes, yet is particularly strengthened by the complete revision of the material on the molecular genetics of chromosomes and chromosomal defects. The mapping and molecular analysis of chromosomes is one of the most exciting and active areas of modern biomedical research, and this book will be invaluable to scientists, students, technicians and physicians with an interest in the function and dysfunction of chromosomes.

The Biology of Reproduction

Author : Giuseppe Fusco
Publisher : Cambridge University Press
ISBN 13 : 1108499856
Total Pages : 491 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis The Biology of Reproduction by : Giuseppe Fusco

Download or read book The Biology of Reproduction written by Giuseppe Fusco and published by Cambridge University Press. This book was released on 2019-10-10 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: A look into the phenomena of sex and reproduction in all organisms, taking an innovative, unified and comprehensive approach.

Sexual Biology and Reproduction in Crustaceans

Author : Thanumalaya Subramoniam
Publisher : Academic Press
ISBN 13 : 0128096063
Total Pages : 526 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Sexual Biology and Reproduction in Crustaceans by : Thanumalaya Subramoniam

Download or read book Sexual Biology and Reproduction in Crustaceans written by Thanumalaya Subramoniam and published by Academic Press. This book was released on 2016-09-27 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sexual Biology and Reproduction in Crustaceans covers crustacean reproduction as it deals with the structural morphology of the gamete-producing primary sex organs, such as the testis and ovary, the formation and maturation of gametes, their fusion during fertilization, and embryonic development that lead to the release of larvae. Constituting a diverse assemblage of animals, crustaceans are best known by their common representatives, such as shrimps, lobsters, and crabs, but also include many more less familiar, but biologically important forms. This work covers the variety of ways in which both male and female gametes are produced by evolving different sexual systems in crustaceans, the range of reproductive systems, and the accordingly, and highly diverse, mechanistic modes of sex determination. In addition, the book features such topics as genetic and environmental determinants in sex determination pattern, variability of mechanisms of fertilization among different species, the origin of different mating systems, the associated mating and brooding behaviors, and the adaptive ability to different environmental conditions with discussion on the evolutionary ecology of social and sexual systems in certain species, which have shown eusocial tendencies, similar to social insects. Marine species occupying diversified ecological niches in tropical and temperate zones reproduce under definitive environmental conditions. Therefore, reproductive ecology of different crustaceans inhabiting different ecological niches also constitutes another important aspect of the work, along with yolk utilization and embryogenesis leading to release of different larval forms, which reflect on their aquatic adaptability. Forms a valuable source of recent references on the current research in crustacean reproductive physiology Covers various mating and breeding systems, providing illustrative examples for sexual selection, parental care of developing eggs and embryos, and the evolution of other reproductive behaviors Features contributions written in the form of review articles, enabling readers to not only gain information in the respective subject, but also help them stimulate ideas in their chosen field of research Includes a glossary created by the author to define technical terms Demonstrates the ability of crustacean species to serve as useful model systems for other organisms, to investigate issues related to sexual conflict, mate choice, and sperm competition Discusses techniques in endocrine research to help researchers in aquaculture develop protocols in the control of reproduction

Genetic Markers of Sex Differentiation

Author : Florence P. Haseltine
Publisher : Springer Science & Business Media
ISBN 13 : 1489919651
Total Pages : 174 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Genetic Markers of Sex Differentiation by : Florence P. Haseltine

Download or read book Genetic Markers of Sex Differentiation written by Florence P. Haseltine and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sex Itself

Author : Sarah S. Richardson
Publisher : University of Chicago Press
ISBN 13 : 022608471X
Total Pages : 320 pages
Book Rating : 4.2/5 (26 download)

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Book Synopsis Sex Itself by : Sarah S. Richardson

Download or read book Sex Itself written by Sarah S. Richardson and published by University of Chicago Press. This book was released on 2013-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human genomes are 99.9 percent identical—with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.