Molecular Genetics Of Brain Tumors

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Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 9535109898
Total Pages : 652 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications by : Terry Lichtor

Download or read book Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-02-27 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular recent new avenues regarding the role of stem cells and microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to chemotherapeutic agents and radiation therapy has been developed. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Advances in Molecular Genetics of Brain Tumors

Author : Nives Pecina-Slaus
Publisher : Mdpi AG
ISBN 13 : 9783036566443
Total Pages : 0 pages
Book Rating : 4.5/5 (664 download)

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Book Synopsis Advances in Molecular Genetics of Brain Tumors by : Nives Pecina-Slaus

Download or read book Advances in Molecular Genetics of Brain Tumors written by Nives Pecina-Slaus and published by Mdpi AG. This book was released on 2023-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book encompasses a number of articles that focus on the molecular blueprint of brain tumors. A collection of relevant papers in the rapidly expanding field of brain tumor molecular genetics broadens our knowledge about the biology of brain tumors, and inspires further studies that will improve the diagnosis and clinical management of brain tumors. Due to the great heterogeneity of brain tumors it is important to research and understand every aspect of their initiation, progression and metastasis in order to design better diagnostic and therapeutic approaches for their clinical management and patient benefit.

The Genetics and Molecular Biology of Neural Tumors

Author : Avery A. Sandberg
Publisher : Springer Science & Business Media
ISBN 13 : 1597455105
Total Pages : 453 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Genetics and Molecular Biology of Neural Tumors by : Avery A. Sandberg

Download or read book The Genetics and Molecular Biology of Neural Tumors written by Avery A. Sandberg and published by Springer Science & Business Media. This book was released on 2008-05-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collecting an extensive amount of information from thousands of publications by leading investigators in this rapidly developing field, this book provides a convenient and up-to-date one volume source for research in neural tumors of various cellular origins. With over 3,500 references, 110 figures and 120 tables, this volume gathers an astonishing body of knowledge regarding human neural tumors. This book is the first of its kind, encyclopedic and wide-ranging.

Molecular Genetics of Brain Tumors

Author : Michelle Alonso
Publisher :
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.:/5 (587 download)

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Book Synopsis Molecular Genetics of Brain Tumors by : Michelle Alonso

Download or read book Molecular Genetics of Brain Tumors written by Michelle Alonso and published by . This book was released on 2001 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 9535110586
Total Pages : 656 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors by : Terry Lichtor

Download or read book Clinical Management and Evolving Novel Therapeutic Strategies for Patients with Brain Tumors written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2013-04-10 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years, and this has lead to the development of novel therapeutic strategies for these patients. In this book a review of the options available for the clinical management of patients with these tumors are outlined. In addition advances in radiology both for pre-operative diagnostic purposes along with surgical planning are described. Furthermore a review of newer developments in chemotherapy along with the evolving field of photodynamic therapy both for intra-operative management and subsequent therapy is provided. A discussion of certain surgical management issues along with tumor induced epilepsy is included. Finally a discussion of the management of certain unique problems including brain metastases, brainstem glioma, central nervous system lymphoma along with issues involving patients with a brain tumor and pregnancy is provided.

Brain Tumor Invasion

Author : Tom Mikkelsen
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 494 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Brain Tumor Invasion by : Tom Mikkelsen

Download or read book Brain Tumor Invasion written by Tom Mikkelsen and published by Wiley-Liss. This book was released on 1998-05-05 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumor Invasion Biological, Clinical, and Therapeutic Considerations Edited by Tom Mikkelsen Rolf Bjerkvig Ole Didrik Laerum Mark L. Rosenblum Recent advances in molecular biology have given us profound new insights into the behavior of primary brain tumors. Not only are such tumors more diffuse in their infiltration of brain tissue and therefore less amenable to surgery than brain tumors originating elsewhere in the body—it now appears that the central nervous system and the normal brain itself constitute a biological environment conducive to the uncontrolled spread of primary tumors. Brain Tumor Invasion is the first comprehensive reference devoted to the invasive behavior of primary brain tumors. It examines the biological mechanisms responsible for the increased ability of gliomas to metastasize in the central nervous system, and discusses the role of chemical carcinogens, growth factors, oncogenes, and tumor suppressors in the progression of such metastases. This book surveys the latest research in the field, reviews present and future prospects of anti-invasive brain tumor therapy, and even translates preclinical trials and other research results into potential new therapies. The material is divided into five main categories: Developmental biology and molecular neuro-oncology Pathological and clinical features of malignant brain tumors Models for the study of brain tumor invasion in vivo and in vitro Mechanisms of invasion New therapeutic strategies Brain Tumor Invasion offers dozens of maps and photographs that illustrate topics under discussion. This in-depth introduction to one of the most difficult problems in the management of brain tumors is indispensable to neuro-oncologists involved in brain tumor research and therapy. It is also useful to researchers in cancer biology, neuroscience, cell biology, and molecular genetics.

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

Author : Herbert B. Newton
Publisher : Academic Press
ISBN 13 : 0128121017
Total Pages : 848 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy by : Herbert B. Newton

Download or read book Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy written by Herbert B. Newton and published by Academic Press. This book was released on 2018-03-28 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Author : Terry Lichtor
Publisher : BoD – Books on Demand
ISBN 13 : 953512031X
Total Pages : 436 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor by : Terry Lichtor

Download or read book Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor written by Terry Lichtor and published by BoD – Books on Demand. This book was released on 2015-03-25 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

The Molecular Genetics of Human Brain Tumors

Author : Deon Jacobus Venter
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis The Molecular Genetics of Human Brain Tumors by : Deon Jacobus Venter

Download or read book The Molecular Genetics of Human Brain Tumors written by Deon Jacobus Venter and published by . This book was released on 1990 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors

Author : O.D. Wiestler
Publisher : Springer Science & Business Media
ISBN 13 : 3642850391
Total Pages : 311 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors by : O.D. Wiestler

Download or read book Molecular Neuro-oncology and Its Impact on the Clinical Management of Brain Tumors written by O.D. Wiestler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumors of the nervous system represent a difficult therapeutic challenge. During recent years, substantial progress has been made in characterizing genetic mechnisms involved in the formation of brain tumors. There is a lot of hope that an understanding of the molecular basis of transformation will eventually lead to specific therapeutic approaches. In this volume, leading authorities in both molecular and clinical neuro-oncology summarize recent developments in their respective fields. The first part of the book will focus on specific molecular genetic defects in neural tumors and their potential clinical significance. Part two gives an update on established and novel treatment regimens for patients with brain tumors. Several contributions will demonstrate that molecular and clinical neuro-oncology are already entangled. With its unique combination of molecular biological and clinical data, this volume provides basic researchers and clinical neuroscientists with a comprehensive update in both disciplines.

Molecular Markers of Brain Tumor Cells

Author : Bela Bodey
Publisher : Springer Science & Business Media
ISBN 13 : 1402028040
Total Pages : 365 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Molecular Markers of Brain Tumor Cells by : Bela Bodey

Download or read book Molecular Markers of Brain Tumor Cells written by Bela Bodey and published by Springer Science & Business Media. This book was released on 2006-03-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.

Brain Tumors

Author : Francis Ali-Osman
Publisher : Springer Science & Business Media
ISBN 13 : 1592598439
Total Pages : 392 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Brain Tumors by : Francis Ali-Osman

Download or read book Brain Tumors written by Francis Ali-Osman and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.

Central Nervous System Tumours

Author : Thomas James Deeley
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Central Nervous System Tumours by : Thomas James Deeley

Download or read book Central Nervous System Tumours written by Thomas James Deeley and published by . This book was released on 1974 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America

Author : Linda M. Liau
Publisher : Elsevier Health Sciences
ISBN 13 : 0323813062
Total Pages : 208 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America by : Linda M. Liau

Download or read book Glioblastoma, Part II: Molecular Targets and Clinical Trials, An Issue of Neurosurgery Clinics of North America written by Linda M. Liau and published by Elsevier Health Sciences. This book was released on 2021-04-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Atlas of Clinical Cases on Brain Tumor Imaging

Author : Yelda Özsunar
Publisher : Springer
ISBN 13 : 9783030232726
Total Pages : 0 pages
Book Rating : 4.2/5 (327 download)

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Book Synopsis Atlas of Clinical Cases on Brain Tumor Imaging by : Yelda Özsunar

Download or read book Atlas of Clinical Cases on Brain Tumor Imaging written by Yelda Özsunar and published by Springer. This book was released on 2020-04-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents and analyzes clinical cases of brain tumors and follows the classification provided by the WHO in 2016. After introductory chapters reviewing the international literature on the topic, the advances made in all imaging modalities (especially Magnetic Resonance and Computed Tomography) are examined.All radiological findings are supplemented with a wealth of images and brief explanations. The clinical information is given as part of the case discussion, as are the characteristics and differential diagnosis of the tumors. Radiologic-pathologic correlations round out the description of each clinical case.Intended as a quick and illustrative reference guide for radiology residents and medical students, this atlas represents the most up-to-date, practice-oriented reference book in the field of Brain Tumor Imaging.