Molecular Cloning Functional Expression And Regional Distribution Of Ciliary Neurotrophic Factor Cntf

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Neurotrophic Factors

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Author : Sandra E. Loughlin
Publisher : Elsevier
ISBN 13 : 0080571328
Total Pages : 632 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Neurotrophic Factors by : Sandra E. Loughlin

Download or read book Neurotrophic Factors written by Sandra E. Loughlin and published by Elsevier. This book was released on 2012-12-02 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. - Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system - Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function - Includes special chapters on primary, secondary, and tertiary messenger systems - Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity

Handbook of Neurochemistry and Molecular Neurobiology

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Author : Ramon Lim
Publisher : Springer Science & Business Media
ISBN 13 : 0387303480
Total Pages : 691 pages
Book Rating : 4.3/5 (873 download)

Book Synopsis Handbook of Neurochemistry and Molecular Neurobiology by : Ramon Lim

Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.

Receptor Chemistry Towards the Third Millennium

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Author : M. Gianella
Publisher : Elsevier
ISBN 13 : 0080540406
Total Pages : 281 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Receptor Chemistry Towards the Third Millennium by : M. Gianella

Download or read book Receptor Chemistry Towards the Third Millennium written by M. Gianella and published by Elsevier. This book was released on 2000-05-31 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptor Chemistry Towards the Third Millennium is the result of papers presented at the 12th Camerino-Noordwijkerhout Symposium, held in Camerino, Italy in September 1999. Although much is known about the way ligands interact with receptors, which have now been isolated, characterized and cloned, many aspects still remain to be explored. In particular, differentiation into distinct subpopulations and the multiplicity of transduction processes offer more specific targets in the search for new drugs. This book will be of interest to medicinal chemists, pharmacologists, biochemists and neurologists and will also be a valuable source of reference for medical students and postgraduate students in related fields.

Gene Transfer and Therapy in the Nervous System

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Author : Fred H. Gage
Publisher : Springer Science & Business Media
ISBN 13 : 3642848427
Total Pages : 226 pages
Book Rating : 4.6/5 (428 download)

Book Synopsis Gene Transfer and Therapy in the Nervous System by : Fred H. Gage

Download or read book Gene Transfer and Therapy in the Nervous System written by Fred H. Gage and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene transfer technology is a powerful tool for increasing our understandingof brain functions. It is also the basis of gene therapy, which is now technically possible for the correction of many human diseases, including several disorders of the nervous (and muscular) system such as Alzheimer's disease, Parkinson's disease, and dystrophy. This volume,which contains the proceedings of a symposium of the Fondation Ipsen, provides a unique view of the state of the art on different transgenes, vectors, target cells, and clinical applications related to the nervous system.

Chemical Factors in Neural Growth, Degeneration and Repair

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Author : C. Bell
Publisher : Elsevier
ISBN 13 : 0080529038
Total Pages : 551 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Chemical Factors in Neural Growth, Degeneration and Repair by : C. Bell

Download or read book Chemical Factors in Neural Growth, Degeneration and Repair written by C. Bell and published by Elsevier. This book was released on 1996-12-17 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

Neuroglia

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Author : Helmut Kettenmann
Publisher : Oxford University Press
ISBN 13 : 0198034741
Total Pages : 1103 pages
Book Rating : 4.1/5 (98 download)

Book Synopsis Neuroglia by : Helmut Kettenmann

Download or read book Neuroglia written by Helmut Kettenmann and published by Oxford University Press. This book was released on 2004-09-30 with total page 1103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroglia is the only comprehensive reference book on the basic biology and function of glial cells. This long-awaited second edition has been completely reorganized and rewritten to include the dramatic advances in this field since the first edition was published ten years ago. The impact of the second edition will be greater than that of the first because the majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. The second edition covers the entire field of glial research from the basic molecular and cellular principles of these cells to their involvement in neurological diseases including stroke, Alzheimer's disease, and multiple sclerosis. It includes new chapters on transmitter release from exocytosis from glia, glia derived stem cells, glia and synaptic transmission, glia and axon guidance, an entirely new section on mechanisms of glial injury, and several new chapters on the roles of glia in different diseases. The new edition was written with both students and experts in mind. It provides a basic introduction to the entire range of glial topics and detailed information with critical assessment of the research literature. Neuroscience textbooks focus on the properties of neurons, whereas this book fills the information void about the brain's other cells. Neuroglia, Second Edition, is an essential reference source for newcomers, including graduate students, to neuroanatomy, neurochemistry, neurophysiology, and molecular neurobiology. It is also a vital companion for established researchers in these fields as well as clinicians in neurology, neurosurgery, psychiatry, neuropathology, and neuro-oncology.

Proceedings

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Author :
Publisher :
ISBN 13 :
Total Pages : 852 pages
Book Rating : 4.3/5 (439 download)

Book Synopsis Proceedings by :

Download or read book Proceedings written by and published by . This book was released on 1991 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Botulinum and Tetanus Neurotoxins

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Author : B.R. DasGupta
Publisher : Springer Science & Business Media
ISBN 13 : 1475795424
Total Pages : 671 pages
Book Rating : 4.4/5 (757 download)

Book Synopsis Botulinum and Tetanus Neurotoxins by : B.R. DasGupta

Download or read book Botulinum and Tetanus Neurotoxins written by B.R. DasGupta and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three days in Madison have thoroughly modified my view on clostridial neurotoxins. While still realizing the numerous activating, modifying and protective inputs, I cannot judge the meaningfulness of the meeting impartially. Neither may the reader expect a complete summary of all presentations. Collected in this volume, they speak for themselves without requiring an arbiter. Instead I shall write down my very personal opinions as a researcher who has studied clostridial neurotoxins for nearly 25 years. Comparable conferences have been rare during this time. A comprehensive symposium 4 on C. botulinum neurotoxins has been organized at Ft. Detrick. International conferences on tetanus have been held regularly under the auspices of the Wodd Health Organization. One or maximally two days of these meetings have been devoted to tetanus toxin and its actions whereas the sponsor and the majority of the participants have been interested mainly in epidemiology, prevention and treatment of tetanus as a disease (see refs. 5,6). Some aspects of clostridial neurotoxins have been addressed in the context of bacterial toxins, in particular in the biennial European workshops. 1-3,7,8 The Madison meeting differed from the previous ones in three aspects. First, it covered both tetanus and botulinum neurotoxins. The fusion was justified because of their huge similarities in primary structure, in their mode of action and in their cellular targets. Second, the meeting was not limited to toxins but drew some lines on which modern neurobiology might proceed.

Progress in Immunology Vol. VIII

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Author : M. Benczur
Publisher : Springer
ISBN 13 : 3642514790
Total Pages : 926 pages
Book Rating : 4.6/5 (425 download)

Book Synopsis Progress in Immunology Vol. VIII by : M. Benczur

Download or read book Progress in Immunology Vol. VIII written by M. Benczur and published by Springer. This book was released on 2013-12-21 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: At this congress there were again numereous reports of progress in immunology. The new technologies are continuing to have an immense impact: gene isolation, mutation, transfection and expression, protein structure andpeptide synthesis, cell cloning, hybridization and monoclonal antibodies, CD serology, SCID and transgenic mice, modern immunomodulation and vaccines. A trmendous mass of data has accumulated over the last years. The reports are up-to-date and outstanding,to a degree no journal will ever achieve, and the results are presented in a concise and lucid way. This report will serve as a guideline for the years to came, because it is a treasure trove of explorations, making it exciting reading. This progress presents outstanding contributions. Immunology is exhibited at its best: an exciting research area and a rewarding subject to study for the benefit of mankind - today more than ever.

NGF and Related Molecules in Health and Disease

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Author : L. Aloe
Publisher : Elsevier
ISBN 13 : 0080497500
Total Pages : 563 pages
Book Rating : 4.0/5 (84 download)

Book Synopsis NGF and Related Molecules in Health and Disease by : L. Aloe

Download or read book NGF and Related Molecules in Health and Disease written by L. Aloe and published by Elsevier. This book was released on 2003-12-10 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.

Amyotrophic Lateral Sclerosis, Second Edition

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Author : Robert H. Brown
Publisher : CRC Press
ISBN 13 : 1000105768
Total Pages : 393 pages
Book Rating : 4.0/5 (1 download)

Book Synopsis Amyotrophic Lateral Sclerosis, Second Edition by : Robert H. Brown

Download or read book Amyotrophic Lateral Sclerosis, Second Edition written by Robert H. Brown and published by CRC Press. This book was released on 2021-12-24 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amyotrophic lateral sclerosis or motor neurone disease is one of the most debilitating and devastating of the neurological diseases. The only comprehensive textbook available on the topic, this completely reorganized and expanded new edition examines all aspects of ALS from pathology to patient care and provides the reader with a ready reference to help with the difficulties encountered in patient diagnosis and treatment. Undoubtedly an important work in the field, this book will be of great interest to clinical neurologists and trainees, and to all those concerned with the care of people with ALS.

Cytokines

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Author : Anthony R. Mire-Sluis
Publisher : Academic Press
ISBN 13 : 0080530214
Total Pages : 609 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Cytokines by : Anthony R. Mire-Sluis

Download or read book Cytokines written by Anthony R. Mire-Sluis and published by Academic Press. This book was released on 1998-04-15 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide both clinicians and researchers in immunology and pharmacology with invaluable information. - Genetic information and sequences - Protein structure - Cell sources and production - Biological activity - Cytokine receptor structure and signal transduction - Discussion of the role of cytokines in disease and the potential for therapy - Summary table of essential facts - Comprehensive bibliography

The Journal of Neuroscience

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Author :
Publisher :
ISBN 13 :
Total Pages : 1022 pages
Book Rating : 4.3/5 (555 download)

Book Synopsis The Journal of Neuroscience by :

Download or read book The Journal of Neuroscience written by and published by . This book was released on 1995 with total page 1022 pages. Available in PDF, EPUB and Kindle. Book excerpt:

CSA Neurosciences Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis CSA Neurosciences Abstracts by :

Download or read book CSA Neurosciences Abstracts written by and published by . This book was released on 1996 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gene Expression in the Central Nervous System

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Author : A.C.H. Yu
Publisher : Elsevier
ISBN 13 : 0080862306
Total Pages : 359 pages
Book Rating : 4.0/5 (88 download)

Book Synopsis Gene Expression in the Central Nervous System by : A.C.H. Yu

Download or read book Gene Expression in the Central Nervous System written by A.C.H. Yu and published by Elsevier. This book was released on 1995-08-01 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene expression is an active ongoing process that maintains a functional CNS, as proteins are being made on a continual basis. Processes such as learning and memory, nerve cell repair and regeneration and its response to stress are critically dependent on gene expression. This volume highlights the role of gene expression in normal CNS function, and presents many research methods at the cutting edge of neuroscience, which will provide insight into therapeutic approaches through which the control of gene expression may be used in the treatment of many nervous system diseases.

Astrocytes

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Author : Bozzano G Luisa
Publisher : Academic Press
ISBN 13 : 0323139876
Total Pages : 478 pages
Book Rating : 4.3/5 (231 download)

Book Synopsis Astrocytes by : Bozzano G Luisa

Download or read book Astrocytes written by Bozzano G Luisa and published by Academic Press. This book was released on 2012-12-02 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the functional roles of astrocytes in the nervous system has grown significantly as it is recognized that these cells not only have their own pharmacology but also release neuro- and vaso-active factors. This book relates astrocyte pharmacology to cell function for the first time, making it an attractive text across the neuroscience community. - Discusses the pharmacological regulation of specific astrocyte functions - Covers functional interactions between these and adjacent CNS cell types - Examines regional heterogeneity of astrocytes with respect to receptor expression - Compares in vitro and in vivo approaches

Clinical Applications of Neurotrophic Factors

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Author : Stuart C. Apfel
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Clinical Applications of Neurotrophic Factors by : Stuart C. Apfel

Download or read book Clinical Applications of Neurotrophic Factors written by Stuart C. Apfel and published by Lippincott Williams & Wilkins. This book was released on 1997 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: