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Author : Dominic Poccia
Publisher : Springer
ISBN 13 :
Total Pages : 176 pages
Book Rating : 4.F/5 ( download)
Download or read book Molecular Aspects of Spermatogenesis written by Dominic Poccia and published by Springer. This book was released on 1994 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : C.Y. Cheng
Publisher : Springer Science & Business Media
ISBN 13 : 0387095977
Total Pages : 289 pages
Book Rating : 4.3/5 (87 download)
Download or read book Molecular Mechanisms in Spermatogenesis written by C.Y. Cheng and published by Springer Science & Business Media. This book was released on 2009-10-24 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.
Author : Rajender Singh
Publisher : CRC Press
ISBN 13 : 0429534426
Total Pages : 338 pages
Book Rating : 4.4/5 (295 download)
Download or read book Molecular Signaling in Spermatogenesis and Male Infertility written by Rajender Singh and published by CRC Press. This book was released on 2019-11-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David de Kretser
Publisher : Elsevier
ISBN 13 : 008091764X
Total Pages : 502 pages
Book Rating : 4.0/5 (89 download)
Download or read book Molecular Biology of the Male Reproductive System written by David de Kretser and published by Elsevier. This book was released on 2012-12-02 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in their respective fields, this book reviews the expanding knowledge concerning the mechanisms regulating male reproduction at the molecular and cellular levels. It covers the development of the testes and regulatory controls for spermatogenesis and steroidogenesis, and it considers aspects of Sertoli cell function. Areas of emphasis include communication between the various cell types involved in reproduction by hormone and growth factors and the mechanisms by which these factors regulate gene expression. A number of mammalian systems, including humans, are covered. The carefully selected authors provide a clear synopsis of the concepts in each area as well as the latest references, enabling the reader to investigate the topic further. This book is of interest to those seeking an understanding of the regulatory mechanisms in male reproduction and is written for the graduate and postgraduate levels. Key Features * Provides up-to-date reviews of the molecular and cellular biology of male reproduction * Includes chapters on the developmental biology of the testes * Links conventional hormonal control of testicular function with the evolving role of growth factors and proto-oncogenes
Author : Claude Desjardins
Publisher : Oxford University Press, USA
ISBN 13 : 9780195062694
Total Pages : 524 pages
Book Rating : 4.0/5 (626 download)
Download or read book Cell and Molecular Biology of the Testis written by Claude Desjardins and published by Oxford University Press, USA. This book was released on 1993 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.
Author : Ricardo Benavente
Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805577465
Total Pages : 0 pages
Book Rating : 4.5/5 (774 download)
Download or read book Molecular Aspects of Mouse Spermatogenesis written by Ricardo Benavente and published by S. Karger AG (Switzerland). This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years considerable progress has been made in the identification, immunolocalization and biochemical characterization of proteins expressed in mammalian spermatogenic cells. However, under culture conditions spermatogenic cells are difficult to investigate and manipulate, a limitation that has often complicated their functional analysis. By using the mouse as a model system, some of these limitations have been overcome. The techniques of producing genetically manipulated (knockout, transgenic, etc.) animals and the host of information provided by the mouse genome project have contributed to the rapid progress in the functional analysis of the spermatogenic proteins of the mouse compared to other mammals. This special topic issue of Cytogenetic and Genome Research presents an excellent overview of recent advances in mouse spermatogenesis research. It will be of special interest to cell and molecular biologists, geneticists and andrologists.
Author : Larry I. Lipshultz
Publisher : Cambridge University Press
ISBN 13 : 1139483242
Total Pages : 691 pages
Book Rating : 4.1/5 (394 download)
Download or read book Infertility in the Male written by Larry I. Lipshultz and published by Cambridge University Press. This book was released on 2009-09-24 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.
Author : Gladys Robinson
Publisher :
ISBN 13 : 9781634847261
Total Pages : 120 pages
Book Rating : 4.8/5 (472 download)
Download or read book Spermatogenesis written by Gladys Robinson and published by . This book was released on 2016 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.
Author : Michael D. Griswold
Publisher : Academic Press
ISBN 13 : 012417048X
Total Pages : 488 pages
Book Rating : 4.1/5 (241 download)
Download or read book Sertoli Cell Biology written by Michael D. Griswold and published by Academic Press. This book was released on 2014-11-19 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years
Author : Mohamed Arafa
Publisher : Springer Nature
ISBN 13 : 3030379728
Total Pages : 374 pages
Book Rating : 4.0/5 (33 download)
Download or read book Genetics of Male Infertility written by Mohamed Arafa and published by Springer Nature. This book was released on 2020-03-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.
Author : Lonnie Dee Russell
Publisher :
ISBN 13 :
Total Pages : 840 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Sertoli Cell written by Lonnie Dee Russell and published by . This book was released on 1993 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Manuela Simoni
Publisher : Springer
ISBN 13 : 9783319444406
Total Pages : 1364 pages
Book Rating : 4.4/5 (444 download)
Download or read book Endocrinology of the Testis and Male Reproduction written by Manuela Simoni and published by Springer. This book was released on 2017-09-18 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
Author : Wolfgang Hennig
Publisher : Springer
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.:/5 (43 download)
Download or read book Spermatogenesis Genetic Aspects written by Wolfgang Hennig and published by Springer. This book was released on 1987-09-16 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spermatogenesis is one of the fundamental but at the same time also one of the most complex differentiation processes in higher eukaryotes. For a long time the development of spermatozoa has been considered as related solely to the needs of transfer of the paternal genome into the egg. Other paternal contributions to the development of the embryo were not seriously considered. Only recently has it become evident, from studies of mouse embryonic development by Solter and colleagues, that also the paternal genome carries regulatory information into the zygote since the development of a mouse embryo requires the presence of the maternal as well as of the paternal pronucleus. This means that we have to pay more attention to the development of male gametes, since the imprinting of the paternal genome obviously required for the early embryonic development must occur during male gamete development. Despite the fundamental character of sperm development as a cellular differentiation process, no coherent concepts for studies of this process exist. Many morphological, and in particular ultrastructural, details of sperm devel opment and sperm structure are known, but this knowledge has not been assembled into a consistent picture reflecting the basic features of this differ entiation process. One of the reasons for the failure to construct such a picture is the fact that also the genetics of sperm development is poorly developed. For elaborating concepts of early embryonic development the study of mutants has been, and still is, indispensible.
Author : Kevin Coward
Publisher : Cambridge University Press
ISBN 13 : 110727625X
Total Pages : 408 pages
Book Rating : 4.1/5 (72 download)
Download or read book Textbook of Clinical Embryology written by Kevin Coward and published by Cambridge University Press. This book was released on 2013-10-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
Author : Lori Barnard
Publisher : Humana Press
ISBN 13 : 9781627030373
Total Pages : 0 pages
Book Rating : 4.0/5 (33 download)
Download or read book Spermatogenesis written by Lori Barnard and published by Humana Press. This book was released on 2012-09-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deficiencies in sperm function are usually the result of spermatogenic defects. Spermatogenesis is a biologically complex and essential process during which spermatogonia undergo meiotic recombination, reduction of the genome to a haploid state, and extensive cellular modifications that result in a motile cell capable of traversing the female reproductive tract, withstanding various potential assaults to viability, and finally successfully fertilizing a mature oocyte to give rise to an embryo. Defects in any step of spermatogenesis or spermatogenesis can lead to male infertility, a disease that affects approximately 5-7% of the population. Spermiogenesis and Spermatogenesis: Methods and Protocols details protocols used in the study of spermatogenesis, clinical analytical protocols, and basic techniques used in clinical andrology laboratories, such as obtaining accurate results for a sperm count, and advanced procedures, such as genome-wide genetic study tools and evaluation of nuclear proteins. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Spermiogenesis and Spermatogenesis: Methods and Protocols is unique in its breadth, and will be a useful reference for clinicians and researchers alike.
Author : E. Nieschlag
Publisher : Springer
ISBN 13 : 9783662028179
Total Pages : 0 pages
Book Rating : 4.0/5 (281 download)
Download or read book Spermatogenesis — Fertilization — Contraception written by E. Nieschlag and published by Springer. This book was released on 2013-10-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Investigations into the mechanisms of spennatogenesis, sperm matura tion and fertilization provide the basis of our understanding of male re productive physiology. Since in recent years molecular and cellular en docrinology has provided particularly important contributions to our knowledge, the European Workshops on Molecular and Celluar Endo crinology of the Testis, held regularly during even years since 1980, have become a prominent forum for researchers in the field to discuss recent findings and exchange new ideas. The most recent of these Testis Workshops, the 7th, was held on May 5 - 10, 1992 at Castle Elmau in the Bavarian Alps. The main lectures of this Workshops form the core of this book. In order to provide a broader view of the current status of male re production research, this volume also contains the proceedings of the Schering Foundation Workshop on "Basic Mechanisms of Reproduc tion and Male Fertility Control" which was held in Berlin on October 31 to November 2, 1991. The topics of the two meetings were planned to complement each other. By combining the proceedings of both workshops, it became possible to produce a book that covers a wide spectrum of current highlights in male reproduction research and pro vides the reader with an up-to-date review of the field. The timeliness of the book is emphasized by the fact that it was al ready available when the 7th European Testis Workshop took place.
