Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Molecular And Cellular Mechanisms Of Neostriatal Function
Download Molecular And Cellular Mechanisms Of Neostriatal Function full books in PDF, epub, and Kindle. Read online Molecular And Cellular Mechanisms Of Neostriatal Function ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Molecular and Cellular Mechanisms of Neostriatal Function by : Marjorie A. Ariano
Download or read book Molecular and Cellular Mechanisms of Neostriatal Function written by Marjorie A. Ariano and published by . This book was released on 1995 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of works discussing current research in the cellular and molecular roles of signalling within the striatum. Chapters on striatial microcircuitry and the role of glial cells in boundary formation are followed by sections exploring the distribution of striatal dopamine receptors, GAD mRNA expression, muscarinic receptor subtypes, and a comprehensive look at the diverse neurochemical interactions made by dopamine with opioids using molecular and cellular approaches. Annotation copyright by Book News, Inc., Portland, OR
Book Synopsis Molecular and Cellular Mechanisms of Neuronal Plasticity by : Yigal H. Ehrlich
Download or read book Molecular and Cellular Mechanisms of Neuronal Plasticity written by Yigal H. Ehrlich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. This volume presents research areas which have not been highlighted in the past. In addition to studies on the involement of functional proteins in neuronal adaptation, this volume presents recent developments on the critical roles of bioactive lipids and nucleotides in these processes. In addition to the widely studied role of second messengers, a review of studies on extracellular phosphorylation systems operating on the surface of brain neurons is presented.The first section of the volume presents studies of basic mechanisms operating in a wide range of adaptive processes. The second section presents recent advances in investigations that have demonstrated the clinical implications of this research. These include: state of the art use of transgenic models in studies of molecular and cellular mechanisms implicated in familial Alzheimer's disease and Amyotrophic Lateral Sclerosis; studies of specific proteins implicated in Alzheimer's disease, including an adapter that binds to the beta-amyloid precurser protein (beta-APP) and the microtubular protein Tau and its membrane-bound counterpart. The advantages of using cell culture models for elucidating the causes of neuronal degeneration and for identifying mechanisms of neuroprotection are also presented among the chapters in the section on clinical implications.
Book Synopsis Cellular and Molecular Mechanisms Underlying Higher Neural Functions by : A. I. Selverston
Download or read book Cellular and Molecular Mechanisms Underlying Higher Neural Functions written by A. I. Selverston and published by . This book was released on 1994-06-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the remarkable advances made in molecular neurobiology over the last ten years, very little progress has been made towards understanding how the brain performs higher functions: cognition, behavior, learning, and memory. One of the greatest challenges facing modern neurobiology, therefore, is the integration of data that comes from disparate levels of analysis. This volume presents the results of the Dahlem conference convened to address these issues. The purpose of the conference was to bring together brain researchers, who approach their work at different conceptual levels, to consider how their results might be synthesized into a more integrated view of how the brain works. To try and accomplish this, two specific examples were chosen: the modulation of neural circuits and the phenomena of long-term potentiation (LTP). Neuromodulation has been studied from the molecular to the behavioral level with dramatic breakthroughs at the circuit level over the last five years. Due to the possibility that it may be the cellular mechanism for certain types of learning and memory, LTP has also been studied at different levels. To assist in understanding LTP and neuromodulation at the molecular, cellular, circuit, and behavioral levels, the background papers written for the meeting are included in this volume. The conference itself was devoted to discussing LTP and neuromodulation from the perspective of each of the different levels, and the results of these discussions are presented in the group reports. Particular emphasis was given to a consideration of how the rapid progress in molecular and cellular neurobiology can be integrated into systems and behavioral neurobiology. Specific suggestions for future research in both areas were discussed thoroughly. This volume presents what is most probably the most authoritative, up-to-date assessment of LTP and neuromodulation currently available. Goal of this Dahlem Workshop: to apply new cellular and molecular concepts to the understanding of plasticity in synapses, cells, local circuits, and defined systems in the mature brain.
Book Synopsis Handbook of Basal Ganglia Structure and Function by : Heinz Steiner
Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2010-03-17 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson's disease, Tourette's syndrome, Huntington's disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. - Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction - Features a truly international cast of the preeminent researchers in the field - Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Book Synopsis Tourette Syndrome by : Davide Martino
Download or read book Tourette Syndrome written by Davide Martino and published by Oxford University Press. This book was released on 2022 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Book Synopsis Brain Dynamics and the Striatal Complex by : Robert Miller
Download or read book Brain Dynamics and the Striatal Complex written by Robert Miller and published by CRC Press. This book was released on 2003-09-02 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Dynamics and the Striatal Complex, the first volume in the Conceptual Advances in Brain Research book series, relates dynamic function to cellular structure and synaptic organization in the basal ganglia. The striatum is the largest nucleus within the basal ganglia and therefore plays an important role in understanding structure/function relationships. Areas covered include dopaminergic input to the striatum, organization of the striatum, and the interaction between the striatum and the cerebral cortex.
Download or read book Microcircuits written by Sten Grillner and published by MIT Press. This book was released on 2006 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading neuroscientists discuss the function of microcircuits, functional modules that act as elementary processing units bridging single cells to systems and behavior. Microcircuits, functional modules that act as elementary processing units bridging single cells to systems and behavior, could provide the link between neurons and global brain function. Microcircuits are designed to serve particular functions; examples of these functional modules include the cortical columns in sensory cortici, glomeruli in the olfactory systems of insects and vertebrates, and networks generating different aspects of motor behavior. In this Dahlem Workshop volume, leading neuroscientists discuss how microcircuits work to bridge the single cell and systems levels and compare the intrinsic function of microcircuits with their ion channel subtypes, connectivity, and receptors, in order to understand the design principles and function of the microcircuits. The chapters cover the four major areas of microcircuit research: motor systems, including locomotion, respiration, and the saccadic eye movements; the striatum, the largest input station of the basal ganglia; olfactory systems and the neural organization of the glomeruli; and the neocortex. Each chapter is followed by a group report, a collaborative discussion among senior scientists. Contributors Lidia Alonso-Nanclares, Hagai Bergman, Maria Blatow, J. Paul Bolam, Ansgar Büschges, Antonio Caputi, Jean-Pierre Changeux, Javier DeFelipe, Carsten Duch, Paul Feinstein, Stuart Firestein, Yves Frégnac, Rainer W. Friedrich, C. Giovanni Galizia, Ann M. Graybiel, Charles A. Greer, Sten Grillner, Tadashi Isa, Ole Kiehn, Minoru Kimura, Anders Lanser, Gilles Laurent, Pierre-Marie Lledo, Wolfgang Maass, Henry Markram, David A. McCormick, Christoph M. Michel, Peter Mombaerts, Hannah Monyer, Hans-Joachim Pflüger, Dietmar Plenz, Diethelm W. Richter, Silke Sachse, H. Sebastian Seung, Keith T. Sillar, Jeffrey C. Smith, David L. Sparks, D. James Surmeier, Eörs Szathmáry, James M. Tepper, Jeff R. Wickens, Rafael Yuste
Book Synopsis Advances in Synaptic Plasticity by : M. Baudry
Download or read book Advances in Synaptic Plasticity written by M. Baudry and published by MIT Press. This book was released on 2000 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, a follow-up to the editors' Synaptic Plasticity (MIT Press,1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Many neurons exhibit plasticity; that is, they can change structurally or functionally, often in a lasting way. Plasticity is evident in such diverse phenomena as learning and memory, brain development, drug tolerance, sprouting of axon terminals after a brain lesion, and various cellular forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression. This book, a follow-up to the editors' Synaptic Plasticity (MIT Press, 1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Contributors Yael Amitai, Michel Baudry, Theodore W. Berger, Pierre-Alain Buchs, A.K. Butler, Franck A. Chaillan, Gilbert A. Chauvet, Marie-Françoise Chesselet, Barry W. Connors, Taraneh Ghaffari, Jay R. Gibson, Ziv Gil, Michel Khrestchatisky, Dietmar Kuhl, Carole E. Landisman, Gilles Laurent, Jim-Shih Liaw, David J. Linden, Katrina MacLeod, Henry Markram, W.V. Morehouse, Dominique Muller, J.A. Napieralski, Santiago Rivera, François S. Roman, Bernard Soumireu-Mourat, Oswald Steward, Mark Stopfer, F.G. Szele, Richard F. Thompson, Nicolas Toni, Bernard Truchet, Misha Tsodyks, K. Uryu, Ascher Uziel, Christopher S. Wallace, Yun Wang, Michael Wehr, Paul F. Worley, Xiaping Xie
Book Synopsis Computational Modelling in Behavioural Neuroscience by : Dietmar Heinke
Download or read book Computational Modelling in Behavioural Neuroscience written by Dietmar Heinke and published by Psychology Press. This book was released on 2009-04-03 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the state-of-the-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience.
Book Synopsis The Synaptic Organization of the Brain by : Gordon M. Shepherd
Download or read book The Synaptic Organization of the Brain written by Gordon M. Shepherd and published by Oxford University Press. This book was released on 2004 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a thorough revision of the standard text on local circuits in the different regions of the brain. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioral and gene-targeting methods.
Author :Kristy Kultas-Ilinsky Publisher :Springer Science & Business Media ISBN 13 :1461512352 Total Pages :370 pages Book Rating :4.4/5 (615 download)
Book Synopsis Basal Ganglia and Thalamus in Health and Movement Disorders by : Kristy Kultas-Ilinsky
Download or read book Basal Ganglia and Thalamus in Health and Movement Disorders written by Kristy Kultas-Ilinsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is comprised of the majority of lecture presentations and a few select posters presented at the International Workshop, "Basal Ganglia and Thalamus in Health and Movement Disorders," held in Moscow, Russia, on May 29-31, 2000. The International Committee responsible for organizing this workshop included Alexander Konovalov, Director, Burdenko Institute of Neurosurgery of the Russian Academy of Medical Sciences, Mahlon DeLong, Chair, Department of Neurology, Emory University, Atlanta, USA, Alim Louis Benabid, Chief, Neurosurgery Service, University of Joseph Fourrier, Grenoble, France, and the two undersigned. The workshop was conceived out of a desire to provide a forum for discussions of both basal ganglia-and motor thalamus-related issues by bringing together basic scientists and clinicians representing different disciplines, research directions, and philosophies. The primary goals were to encourage an exchange of information and ideas in an informal environment, to stimulate integration of the data from different disciplines, and to identifY controversial issues and the most essential questions to be addressed in future research.
Download or read book Dopamine written by S.B. Dunnett and published by Elsevier. This book was released on 2004-12-18 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dopamine is a major neurotransmitter of the brain involved in the control of movement, emotion, and cognition; disturbance in dopamine function is associated with disorders like Parkinson’s disease, schizophrenia and attention deficit hyperactivity disorder. This volume of the Handbook of Chemical Neuroanatomy provides a series of in depth critical reviews of our present understanding of the most important aspects of dopamine’s organisation and disturbed function in the animal and human brain.
Book Synopsis The Basal Ganglia VI by : Ann M. Graybiel
Download or read book The Basal Ganglia VI written by Ann M. Graybiel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, the sixth in the IBAGS series, summarizes major contributions in clinical and basic research on the basal ganglia. The sixth meeting of the Society was held on Cape Cod, in the state of Massachusetts, USA, in October, 1998. Altogether 16 countries were represented by 227 participants. This volume contains papers contributed by participants. The focus of the sixth triennial IBAGS meeting, and of this volume, was to bring to gether leaders in basic and clinical science to address two sets of still-persisting questions in the field. The first set focuses on the functions of the basal ganglia in health and disease: What are the core functions of the basal ganglia and cortico-basal ganglia loops? How are these core functions disrupted in disorders affecting the basal ganglia? How do we account for the broad range of behaviors affected by basal ganglia disorders and for the increasing evidence that the basal ganglia influence cognitive as well as motor functions? These issues are addressed in the first five sections of the current volume, which summarize advances in the study of basal ganglia disorders based on studies in humans (Section 1), new results obtained with experimental animal models of basal ganglia disorders (Section 2), results of experiments on information coding in the basal ganglia (Section 3) and new information about functions of the basal ganglia related to learning and adaptive motor control (Section 4).
Book Synopsis Receptor Localization by : Marjorie Ariano
Download or read book Receptor Localization written by Marjorie Ariano and published by John Wiley & Sons. This book was released on 1998-07-16 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection of neurotransmitter receptor locations and distribution densities within the central nervous system and peripheral tissues is receiving intense attention within the neuroscience research community. Neurotransmitter receptors, which receive the chemical signals sent from one neuron to another, are critical links in a highly complex information-processing chain. Pinpointing receptor sites and systems is crucial for understanding neurological function as well as dysfunction. It is also essential for understanding how receptors process information when impacted by such substances as heroin or nicotine, or when affected by neurodegenerative disease. Receptor Localization: Laboratory Methods and Procedures is the first user-friendly guide to the latest techniques and approaches being employed to examine the localization of neurotransmitter receptors in the central nervous system and peripheral tissues. It covers detection methods that are applicable to a wide variety of receptor systems, ranging from genes and ligands to in vito receptors in individuals; and to numerous receptor subtypes, such as nicotine, muscarine, tackykinins, dopamine, adenosine, and GABA. The standard laboratory "recipes" or "tricks" employed in these detection methods are fully discussed, as are the advantages and limitations of each procedure. With contributions from leading experts and extensively illustrated, this book: * Discusses receptor ligand binding methods using irreversible and reversible compounds * Presents antireceptor antisera technology using synthetic peptides and fusion proteins at both the cellular and subcellular resolution levels * Examines molecular assessments of receptors * Describes in situ hybridization, reverse transcriptase-PCR, and fluorescent in situ transcription * Covers new visualization paradigms * Includes physiological analysis of receptor function, cellular detection in the brain slice, and cultured neurons * Discusses the use of PET and SPECT to assess in vivo receptor distributions in animals and humans Receptor Localization: Laboratory Methods and Procedures is an invaluable guide for researchers in the related fields of neurology, biochemistry, and pharmacology. Its lucid descriptions of new detection methods, inclusion of experimental examples, and emphasis on how these experimental approaches are applicable to particular research areas will appeal to both the experienced researcher and novice investigator.
Download or read book Brain Mapping written by Arthur W. Toga and published by Gulf Professional Publishing. This book was released on 2000-04-26 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "sequel" to "Brain Mapping: The Methods", covers the utlization of methods for the study of brain structure and function. Organized by systems, it presents information on the normal as well as the diseased brain. It integrates the various methodologies with appropriate usage.
Book Synopsis The Basal Ganglia VIII by : John Paul Bolam
Download or read book The Basal Ganglia VIII written by John Paul Bolam and published by Springer Science & Business Media. This book was released on 2006-06-26 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the International Meetings of the Basal Ganglia Society (IBAGS) is to provide a unique environment for the open presentation and discussion of new and challenging information about the basal ganglia as it relates to health and disease, covering all areas of basic science and research. Specific topics of the proceedings of this Eighth International Triennial Meeting of the Basal Ganglia Society include behavior, circuitry, functional imaging, modelling, movement disorders, neuropathology, neurotransmitters, pharmacology, physiology, plasticity, treatments for basal ganglia disorders, ventral systems, health and disease, immunology and basal ganglia, and much more.
Book Synopsis Handbook of Parkinson's Disease by : Rajesh Pahwa
Download or read book Handbook of Parkinson's Disease written by Rajesh Pahwa and published by CRC Press. This book was released on 2003-03-25 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this reference has new and fully updated chapters that feature discoveries and breakthroughs in the diagnosis and management of Parkinson's disease.
