Molecular And Cellular Mechanisms Of Anesthetics

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Molecular and Cellular Mechanisms of Anesthetics

Author : S.H. Roth
Publisher : Springer
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular and Cellular Mechanisms of Anesthetics by : S.H. Roth

Download or read book Molecular and Cellular Mechanisms of Anesthetics written by S.H. Roth and published by Springer. This book was released on 1986-03-31 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: B. Raymond Fink Sheldon Roth and Keith Miller have asked me to record that the Third Conference on Molecular and Cellular Mechanisms of Anesthesia was held in Calgary last May "in my honor. " Such was my dear friends' gracious way of continuing a series that began at the University of Washington, where I hosted two, four, or five previous ones, 1,3-6 depending 2 on how far back one wishes to count. At that, Seattle took up where Paris left off in 1951. These occasions create their own unforgettable memories. This book captures the fine, invigorating ambience of the University of Calgary and the exciting explorations and com panionship of a gathering in a frontier territory of neuroscience. So, floreant symposia. They have progressively refined the quarry, from pathway to synapse to lipoprotein membrane to receptor and single channel, in heuristic convergences of neuronal physiology, biochemistry, and pharmacology. Nevertheless, the anesthesiologist in me senses a certain disquiet, a certain claustrophobia provoked by the narrow confines of micropipettes. How much more tubular must tunnel vision become before the desired broad view emerges? At present, the advances in molecular neurobiology seem continually to increase the apparent complexity of the total problem and the conceptual distance between the reductionists in the laboratories and the holists in the operating rooms. Happily, what is also growing is the excitement in trying to bridge the gap. Perhaps it would be timely to regard general anesthesia not as a state but as a syndrome.

Molecular and Cellular Mechanisms of Alcohol and Anesthetics

Author : Emanuel Rubin
Publisher :
ISBN 13 : 9780897666626
Total Pages : 848 pages
Book Rating : 4.6/5 (666 download)

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Book Synopsis Molecular and Cellular Mechanisms of Alcohol and Anesthetics by : Emanuel Rubin

Download or read book Molecular and Cellular Mechanisms of Alcohol and Anesthetics written by Emanuel Rubin and published by . This book was released on 1991 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neural Mechanisms of Anesthesia

Author : Joseph E. Antognini
Publisher : Springer Science & Business Media
ISBN 13 : 1592593224
Total Pages : 464 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Neural Mechanisms of Anesthesia by : Joseph E. Antognini

Download or read book Neural Mechanisms of Anesthesia written by Joseph E. Antognini and published by Springer Science & Business Media. This book was released on 2002-08-22 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading investigators critically evaluate the latest information on how anesthetics work at the molecular, cellular, organ, and whole animal level. These distinguished experts review anesthetic effects on memory, consciousness, and movement and spell out in detail both the anatomic structures and physiological processes that are their likely targets, as well as the cellular and molecular mechanisms by which they operate. Comprehensive and authoritative, Neural Mechanisms of Anesthesia draws together and critically reviews all the recent research on anesthetic mechanisms, highlighting the precise routes along which these substances operate, and how this deeper understanding will lead to the design of effective drugs free ofundesirable side effects.

Molecular Mechanisms of Anesthesia

Author : B. Raymond Fink
Publisher :
ISBN 13 :
Total Pages : 682 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Molecular Mechanisms of Anesthesia by : B. Raymond Fink

Download or read book Molecular Mechanisms of Anesthesia written by B. Raymond Fink and published by . This book was released on 1975 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Alcohol, Cell Membranes, and Signal Transduction in Brain

Author : Christer Alling
Publisher : Springer Science & Business Media
ISBN 13 : 1461524709
Total Pages : 320 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Alcohol, Cell Membranes, and Signal Transduction in Brain by : Christer Alling

Download or read book Alcohol, Cell Membranes, and Signal Transduction in Brain written by Christer Alling and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol abuse and alcoholism are international problems whose costs economical ly, psychologically and medically have been well documented. Alcohol is a unique drug in that the effects of excessive use can have a deleterious effect on most if not all organs of the body. The brain is one of the organs most affected by excessive alcohol consumption. Effects on the brain can be seen in cognitive function, brain structure and neurochemistry. Over the past few years, there have been significant advances made in understanding how alcohol affects brain neurochemistry. This book examines four major areas, i. e. , membrane lipids, receptors and ion channels, second messengers, and gene expression, where significant advancements have been made. The book is divided into four sections based on the four major areas. In each section, data are examined that cover a range of approaches from in vitro to in vivo studies. The section on membrane lipids includes recent developments in how ethanol affects membrane cholesterol domains, polyunsaturated fatty acids, the cause and consequences of phosphatidylethanol formation, and the modulation of membrane protein function by lipid-protein interaction. The second section comprises chapters on NMDA and 5-HT3 receptors, including new aspects on alcohol neurotoxicity and the molecular heterogeneity that may underlie differences in alcohol sensitivity as well as chapters on GABA-gated chloride flux, and calcium channels.

Chemical and Biochemical Approaches for the Study of Anesthetic Function

Author :
Publisher : Academic Press
ISBN 13 : 0128127414
Total Pages : 432 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Chemical and Biochemical Approaches for the Study of Anesthetic Function by :

Download or read book Chemical and Biochemical Approaches for the Study of Anesthetic Function written by and published by Academic Press. This book was released on 2018-03-26 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A, Volume 602 assembles new information on our understanding of anesthesia. This latest release in the series includes sections on how physical accuracy leads to biological relevance, best practices for simulating ligand-gated ion channels interacting with general anesthetics, computational approaches for studying voltage-gated ion channels modulation by general anesthetics, anesthetic parameterization, pharmacophore QSAR, QM, ONIOM, and kinetic modeling of electrophysiology data. We have selected the primary experts to write about each approach This provides one-stop shopping for all the means of addressing this complex question Anesthesia is enormously important as almost everybody receives it at some point

Molecular and Basic Mechanisms of Anesthesia

Author : Bernd W. Urban
Publisher :
ISBN 13 : 9783936142419
Total Pages : 586 pages
Book Rating : 4.1/5 (424 download)

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Book Synopsis Molecular and Basic Mechanisms of Anesthesia by : Bernd W. Urban

Download or read book Molecular and Basic Mechanisms of Anesthesia written by Bernd W. Urban and published by . This book was released on 2002 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular and Basic Mechanisms of Anesthesia

Author : Bernd W. Urban
Publisher : Pabst Science Publishers
ISBN 13 : 9781593260019
Total Pages : 586 pages
Book Rating : 4.2/5 (6 download)

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Book Synopsis Molecular and Basic Mechanisms of Anesthesia by : Bernd W. Urban

Download or read book Molecular and Basic Mechanisms of Anesthesia written by Bernd W. Urban and published by Pabst Science Publishers. This book was released on 2002-01-01 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthesis of Essential Drugs

Author : Ruben Vardanyan
Publisher : Elsevier
ISBN 13 : 9780080462127
Total Pages : 634 pages
Book Rating : 4.4/5 (621 download)

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Book Synopsis Synthesis of Essential Drugs by : Ruben Vardanyan

Download or read book Synthesis of Essential Drugs written by Ruben Vardanyan and published by Elsevier. This book was released on 2006-03-10 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references

Recent Advances in Anaesthesia and Analgesia

Author : A. P. Adams
Publisher : W.B. Saunders Company
ISBN 13 : 9780443059889
Total Pages : 224 pages
Book Rating : 4.0/5 (598 download)

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Book Synopsis Recent Advances in Anaesthesia and Analgesia by : A. P. Adams

Download or read book Recent Advances in Anaesthesia and Analgesia written by A. P. Adams and published by W.B. Saunders Company. This book was released on 1998 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topics covered in this volume include: molecular and cellular mechanisms of general anaesthesia; developments in neuromuscular transmission; and management of the brain injured patient presenting for non-neurosurgical procedures.

Anesthetic Pharmacology

Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Suppressing the Mind

Author : Anthony Hudetz
Publisher : Springer Science & Business Media
ISBN 13 : 1607614626
Total Pages : 256 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Suppressing the Mind by : Anthony Hudetz

Download or read book Suppressing the Mind written by Anthony Hudetz and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anesthetics produce a reversible state of unconsciousness accompanied by ante- grade amnesia. This remarkable phenomenon brings great relief to surgical patients and wonder to clinicians and scientists. To date, we do not fully understand the mechanisms by which anesthetics ablate conscious sensation and memory. We are, however, making progress. This book presents original results as well as overviews of the current state of knowledge of the problem. It is authored by investigators who know the ?eld well; their research at a number of levels has contributed substantially to our c- rent understanding of anesthetic modulation of memory and consciousness. Most of the contributors were presenters at two workshops organized by Dr. Pearce and Dr. Hudetz at the 40th Annual Winter Conference on Brain Research, held at Snowmass Village, Colorado, from January 27 through February 2, 2007. One workshop focused on anesthetic modulation of consciousness and another on an- thetic modulation of memory. Seven of the chapters are based on material presented at these symposia – appropriately updated with new relevant ?ndings. This infor- tion is supplemented by chapters on anesthesia and sleep, computational analysis of the state of anesthesia, and the clinical phenomenon of “anesthesia awareness,” a topic that has recently received much public attention. With these three additional contributions, the book thus includes 10 chapters.

Handbook of Cardiac Anatomy, Physiology, and Devices

Author : Paul A. Iaizzo
Publisher : Springer
ISBN 13 : 331919464X
Total Pages : 817 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Handbook of Cardiac Anatomy, Physiology, and Devices by : Paul A. Iaizzo

Download or read book Handbook of Cardiac Anatomy, Physiology, and Devices written by Paul A. Iaizzo and published by Springer. This book was released on 2015-11-13 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Synthesis of Best-Seller Drugs

Author : Ruben Vardanyan
Publisher : Academic Press
ISBN 13 : 0124115241
Total Pages : 868 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Synthesis of Best-Seller Drugs by : Ruben Vardanyan

Download or read book Synthesis of Best-Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Pharmacology and Physiology for Anesthesia E-Book

Author : Hugh C. Hemmings
Publisher : Elsevier Health Sciences
ISBN 13 : 0323568866
Total Pages : 986 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Pharmacology and Physiology for Anesthesia E-Book by : Hugh C. Hemmings

Download or read book Pharmacology and Physiology for Anesthesia E-Book written by Hugh C. Hemmings and published by Elsevier Health Sciences. This book was released on 2018-10-19 with total page 986 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology and physiology are the foundation of every anesthesia provider’s training and clinical competency. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2nd Edition, delivers the information you need in pharmacology, physiology, and molecular-cellular biology, keeping you current with contemporary training and practice. This thoroughly updated edition is your one-stop, comprehensive overview of physiology, and rational anesthetic drug selection and administration, perfect for study, review, and successful practice. Contains new chapters on Special Populations (anesthetic pharmacology in obesity, geriatrics, and pediatrics), Oral and Non-IV Opioids, Thermoregulation, Physiology and Pharmacology of Obstetric Anesthesia, Chemotherapeutic and Immunosuppresive Drugs, and Surgical Infection and Antimicrobial Drugs. Incorporates entirely new sections on Physics, Anatomy, and Imaging. Includes new information on consciousness and cognition, pharmacodynamics, the immune system, and anti-inflammatory drugs. Features user-friendly tables, figures, and algorithms (including 100 new illustrations), all presented in full color and designed to help explain complex concepts. Helps you understand the molecular mechanism of drug actions and identify key drug interactions that may complicate anesthesia with dedicated sections on these areas.

Molecular and Cellular Mechanisms of Alcohol and Anesthetics

Author : Emanuel Rubin
Publisher :
ISBN 13 :
Total Pages : 872 pages
Book Rating : 4.X/5 (1 download)

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Book Synopsis Molecular and Cellular Mechanisms of Alcohol and Anesthetics by : Emanuel Rubin

Download or read book Molecular and Cellular Mechanisms of Alcohol and Anesthetics written by Emanuel Rubin and published by . This book was released on 1991 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular and Cellular Mechanisms in Disease

Author : J.L. VanLancker
Publisher : Springer Science & Business Media
ISBN 13 : 3642659675
Total Pages : 638 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Molecular and Cellular Mechanisms in Disease by : J.L. VanLancker

Download or read book Molecular and Cellular Mechanisms in Disease written by J.L. VanLancker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of ingenious experiments, imaginative theories, and unshakable faith in supreme forces, there is no way to know how life began. What is certain is that in the course of the development of the universe existing sources of energy fused to generate atoms, and atoms mingled to become small molecules. At some point by chance or design-according to one's belief, but no one's evidence-small molecules such as hydrogen, oxygen, carbon dioxide, water, and ammonia reacted to yield larger molecules with the property most essential to life: self-replication. Such molecules had to achieve a proper balance between the stability needed for their survival in the environment and the mutability for the generation of many forms of life. How amino acids were created or how DNA, RNA, and proteins developed remains a mystery. But we know that a simple core of nucleic acid embedded in a protein coat made the simplest unit of life (except for viroids). Whether viruses are a primitive or degenerated form of life is not known. Once proteins appeared, their great structural plasticity allowed them to react with other elements such as sulfur, iron, copper, and zinc. After an incalculable number of years, some of the proteins became capable of catalyzing the synthesis of new nucleic acids, new proteins, and other compounds such as polysaccharides and lipids.