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Modified Ambient Mass Spectrometric Methods For Field Screening And Confirmation Of Forensic Evidence
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Book Synopsis Ambient Ionization Mass Spectrometry by : Marek Domin
Download or read book Ambient Ionization Mass Spectrometry written by Marek Domin and published by Royal Society of Chemistry. This book was released on 2014-11-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.
Book Synopsis Direct Analysis in Real Time Mass Spectrometry by : Yiyang Dong
Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.
Book Synopsis Forensic Analysis on the Cutting Edge by : Robert D. Blackledge
Download or read book Forensic Analysis on the Cutting Edge written by Robert D. Blackledge and published by John Wiley & Sons. This book was released on 2007-07-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title brings forensic scientists and chemists up-to-date on the latest instrumental methods for analysing trace evidence, including mass spectrometry, image analysis, DIOS-MS, ELISA characterization, statistical validation, and others. Illustrates comparative analysis of trace evidence by both old and new methods. Explains why some newer methods are superior to older, established methods. Includes chapters on analysis of DNA, ink, dyes, glitter, gun powder traces, condom trace evidence, footwear impressions, toolmark impressions, surveillance videos, glass particles, and dirt. Discusses applications such as mass spectrometry, image analysis, desorption-ionization on silicon mass spectrometry (DIOS-MS), ELISA characterization, and statistical validation.
Book Synopsis Opportunities to Improve Airport Passenger Screening with Mass Spectrometry by : National Research Council
Download or read book Opportunities to Improve Airport Passenger Screening with Mass Spectrometry written by National Research Council and published by National Academies Press. This book was released on 2004-05-12 with total page 57 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protection of the traveling public from terrorist threats involving explosives is a major goal of the Transportation Security Administration (TSA). For 20 years, the TSA (and the Federal Aviation Administration before it) have been investing in technologies to meet that goal. To support that activity, the TSA has asked the NRC to assess a variety of technological opportunities for offering such protection. The NRC is approaching this assignment by issuing a series of reports on chosen technology applications. This is the first of that series and presents an assessment of mass spectrometry for enhanced trace detection (ETD) of chemicals contained in explosives. The report describes limitations of trace detection in general and the current technologies in particular. It then presents a discussion of the potential for mass spectrometry to improve EDT including challenges faced by such a system, recommendations for starting a program to take advantage of mass spectrometry, and recommendations for a phased implementation plan.
Book Synopsis Applications of Mass Spectrometry for the Provision of Forensic Intelligence by : Simona Francese
Download or read book Applications of Mass Spectrometry for the Provision of Forensic Intelligence written by Simona Francese and published by Royal Society of Chemistry. This book was released on 2023-12-20 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is one of the most versatile analytical techniques due to the vast range of analytes that it can detect and quantify and, as such, for its contribution to a significant number of life science fields. The legal and forensics community has certainly benefited from this technique, which has been able to provide reliable evidence in court cases. Liquid Chromatography/Gas Chromatography–Mass Spectrometry (LC/GC–MS) still have a dominant role in the provision of forensic intelligence. However, in the past decade new and exciting MS-based techniques have emerged and are or have evolved to be at an operational deployment maturity, enabling either fast, ambient, non-destructive, or portable screening (or encompass all of these features). In this book, developments of LC–MS and GC–MS based techniques are covered with respect to operational practice and new applications, accompanied by other MS-based techniques that are increasing forensic opportunities and that operate on a variety of evidence types. Whilst the underpinning working principles of each relevant mass spectrometry technique are summarised, each chapter primarily focuses on its implementation in criminal investigation and court cases. In the last chapters, this book additionally covers emerging MS technologies that are at the beginning of their operational implementation journey as well as niche applications outside the fields of traditional forensic science but with a clear potential to impact future investigations (forensics beyond the courtroom). This book provides an up-to-date reference for the mass spectrometry-based tools that are currently available both as established and as emerging methods within forensic practice. It will help casework commissioning managers and forensic providers worldwide to make more informed decisions as to the forensic strategy and workflow when examining exhibits. It is also recommended to postgraduates and early career investigators with reference to the contribution that these techniques and methods could make if applied to classic forensic science practice.
Book Synopsis Pulsed Electrochemical Detection in High-Performance Liquid Chromatography by : William R. LaCourse
Download or read book Pulsed Electrochemical Detection in High-Performance Liquid Chromatography written by William R. LaCourse and published by Wiley-Interscience. This book was released on 1997-08-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reliable, comprehensive, relevant view of HPLC and its applications The development of HPLC-PED represents the successful marriage of two powerful analytical technologies and has resulted in the best technique for sensitive and direct detection of biological compounds with poor optical detection properties. PED has been used extensively for the determination of carbohydrates and other polar aliphatic compounds, and as a result, numerous methods have been developed to enable the analysis of a wide variety of samples. Over the years, many articles, anecdotal information, and misinformation have permeated the scientific community, with the possible consequence of confusion or uncertainty with regard to PED on the part of the analyst. Pulsed Electrochemical Detection in High-Performance Liquid Chromatography presents a reliable, comprehensive, and relevant review of HPLC-PED and its applications. The book is divided into three major parts: background material necessary for a more thorough understanding of the principles and relevance of PED; an in-depth discussion of PED using voltammetry and other electroanalytical techniques and presenting the advantages, applicability, and optimization of all existing PED waveforms; and practical aspects of HPLC-PED, including a summary of the major applications and a look at future developments in the technique. Appendices include a pulsed voltammetry (PV) program specifically written to optimize pulsed amperometric detection (PAD) waveforms and all the known applications, categorized and listed in tabular form. For analytical chemists; biochemists; carbohydrate chemists; biotechnologists; undergraduate, graduate, and postdoctoral students; and lab technicians working in a range of areas including the pharmaceutical, medical, and food and beverage industries, this eminently readable guide is the first reliable book-length treatment of how to use PED coupled with HPLC.
Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai
Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. - Provides concrete examples of the main applications of mass spectrometry technology - Describes current capabilities of the LC- and MS-based analytical methods - Details methods for successful analytical work in the field
Book Synopsis Light in Forensic Science by : Giorgia Miolo
Download or read book Light in Forensic Science written by Giorgia Miolo and published by Royal Society of Chemistry. This book was released on 2018-04-16 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification and quantification of material present and collected at a crime scene are critical requirements in investigative analyses. Forensic analysts use a variety of tools and techniques to achieve this, many of which use light. Light is not always the forensic analyst’s friend however, as light can degrade samples and alter results. This book details the analysis of a range of molecular systems by light-based techniques relevant to forensic science, as well as the negative effects of light in the degradation of forensic evidence, such as the breakage of DNA linkages during DNA profiling. The introductory chapters explain how chemiluminescence and fluorescence can be used to visualise samples and the advantages and limitations of available technologies. They also discuss the limitations of our knowledge about how light could alter the physical nature of materials, for example by breaking DNA linkages during DNA profiling or by modifying molecular structures of polymers and illicit drugs. The book then explains how to detect, analyse and interpret evidence from materials such as illicit drugs, agents of bioterrorism, and textiles, using light-based techniques from microscopy to surface enhanced Raman spectroscopy. Edited by active photobiological and forensic scientists, this book will be of interest to students and researchers in the fields of photochemistry, photobiology, toxicology and forensic science.
Book Synopsis Mass Spectrometry by : Marek Smoluch
Download or read book Mass Spectrometry written by Marek Smoluch and published by John Wiley & Sons. This book was released on 2019-07-11 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule. Provides a description of mass spectrometry basics, applications and perspectives of the technique Oriented to a broad audience with limited or basic knowledge in mass spectrometry instrumentation, theory, and its applications in order to enhance their competence in this field Covers all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS with special attention to application of various methodologies and data interpretation Includes a list of key terms, and test questions, for easier and faster understanding of the material Mass Spectrometry: An Applied Approach is highly recommended for advanced students, young scientists, and anyone involved in a field that utilizes the technique.
Book Synopsis Microbial Forensics by : Bruce Budowle
Download or read book Microbial Forensics written by Bruce Budowle and published by Academic Press. This book was released on 2010-10-27 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease
Book Synopsis Mass Spectrometry by : Edmond de Hoffmann
Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI
Book Synopsis Differential Ion Mobility Spectrometry by : Alexandre A. Shvartsburg
Download or read book Differential Ion Mobility Spectrometry written by Alexandre A. Shvartsburg and published by CRC Press. This book was released on 2008-12-24 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, scientific and engineering interests have been shifting from conventional ion mobility spectrometry (IMS) to field asymmetric waveform ion mobility spectrometry (FAIMS). Differential Ion Mobility Spectrometry: Nonlinear Ion Transport and Fundamentals of FAIMS explores this new analytical technology that separates and characterizes ions by the difference between their mobility in gases at high and low electric fields. It also covers the novel topics of higher-order differential IMS and IMS with alignment of dipole direction. The book relates the fundamentals of FAIMS and other nonlinear IMS methods to the physics of gas-phase ion transport. It begins with the basics of ion diffusion and mobility in gases, covering the main attributes of conventional IMS that are relevant to all IMS approaches. Building on this foundation, the author reviews diverse high-field transport phenomena that underlie differential IMS. He discusses the conceptual implementation and first-principles optimization of FAIMS as a filtering technique, emphasizing the dependence of FAIMS performance metrics on instrumental parameters and properties of ion species. He also explores ion reactions in FAIMS caused by field heating and the effects of inhomogeneous electric field in curved FAIMS gaps. Written by an accomplished scientist in the field, this state-of-the-art book supplies the foundation to understand the new technology of nonlinear IMS methods.
Book Synopsis Handbook of Forensic Drug Analysis by : Fred Smith
Download or read book Handbook of Forensic Drug Analysis written by Fred Smith and published by Elsevier. This book was released on 2004-12-31 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science. - Contributed to by leading scientists from around the world - The only analysis book dedicated to illicit drugs of abuse - Comprehensive coverage of sampling methods and various forms of analysis
Book Synopsis Comprehensive Environmental Mass Spectrometry by : Albert Lebedev
Download or read book Comprehensive Environmental Mass Spectrometry written by Albert Lebedev and published by ILM Publications. This book was released on 2012 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In full colour throughout, this book describes the power of mass spectrometry in resolving environmental issues, demonstrating how real-world complex problems can be solved in a simple and elegant way."--Worldcat.
Book Synopsis Mass Spectrometry by : Jürgen H Gross
Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.
Book Synopsis Advances in Forensic Applications of Mass Spectrometry by : Jehuda Yinon
Download or read book Advances in Forensic Applications of Mass Spectrometry written by Jehuda Yinon and published by CRC Press. This book was released on 2003-12-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass
Download or read book Lipidomics written by William Griffiths and published by Royal Society of Chemistry. This book was released on 2020-01-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipidomics is one of the emerging ‘omics’ techniques with growing importance in bioscience. Discussing interesting standard and non-standard techniques relevant to the measurement and analysis of lipids by mass spectrometry, this book will provide a guide to the possibilities of the techniques. It will introduce the reader to exciting new methods that allow isomer differentiation, improve sensitivity, allow spatial location and go beyond annotation of simply matching a mass to a database entry. The book is written and edited by the some of the world leaders in the field of lipid mass spectrometry and will have international appeal in industry and academia for analytical chemists, biochemists and biotechnologists. Furthermore, it will provide a useful resource for anyone interested in lipid structure characterization particularly for graduates and postgraduates who require a starting point for their projects.
