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Author :
Publisher :
ISBN 13 :
Total Pages : 521 pages
Book Rating : 4.:/5 (126 download)
Download or read book Modern Trends in Human Leukemia VI. written by and published by . This book was released on 1985 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rolf Neth
Publisher : Springer Science & Business Media
ISBN 13 : 3642703852
Total Pages : 544 pages
Book Rating : 4.6/5 (427 download)
Download or read book Modern Trends in Human Leukemia VI written by Rolf Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 17-20, 1984 Wilsede Joint Meeting on Pediatric Oncology III. Hamburg, June 21/22, 1984.
Author : Rolf Neth
Publisher : Springer Science & Business Media
ISBN 13 : 3642746217
Total Pages : 580 pages
Book Rating : 4.6/5 (427 download)
Download or read book Modern Trends in Human Leukemia VIII written by Rolf Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: You see things, and sa)' why? But I dream 1hings that never were, and I say, 11'hy 110t? George Bernhard Shaw Far ahead of his time, June 1st, 1909, Alexander Maximov communicated in a lecture, given in the Charite in Berlin, the fundamental knowledge, that there exists a lymphoid hemopoetic stem cell. Alexander Friedenstein explained that during the following years, Maximov also showed that the idea of interaction between hemopoetic cells and their stroma to be one of the most significant experiences. Monoclonal antibodies, recombinant DNA technics and the improvement of tissue culture models are the major developments to improve our possibilities to clarify growth and differentiation functions of hemopoetic cells. During the last two decades it was shown that soluble products, released from T cells, were not only involved in inducing B cells to produce specific immunoglobulin secretion after antigen stimulation. Furthermore, lymphokines together with other cytokines regulate the growth and differentiation of hemopoetic cells. As I have learned from Dick Gershon, our knowledge of the cellular basis for immunoregulation has come a long way since 450 B.C. Thucydides comments on the possible role of immune response in controlling the Black Death. Dick Gershon speculated that no scientific interest for these interesting observations was put forth at that time. Perhaps the problems, the Athenians were having with the Spartans, converted money from basis research into the military budget.
Author : Rolf Neth
Publisher :
ISBN 13 : 9783642875250
Total Pages : 592 pages
Book Rating : 4.8/5 (752 download)
Download or read book Modern Trends in Human Leukemia II written by Rolf Neth and published by . This book was released on 2014-09-01 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rolf Neth
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (461 download)
Download or read book Modern Trends in Human Leukemia written by Rolf Neth and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rolf Neth
Publisher :
ISBN 13 :
Total Pages : 580 pages
Book Rating : 4.3/5 (91 download)
Download or read book Modern Trends in Human Leukemia VII written by Rolf Neth and published by . This book was released on 1987 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert C. Gallo
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (131 download)
Download or read book Modern Trends in Human Leukemia V written by Robert C. Gallo and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rolf Neth
Publisher :
ISBN 13 : 9783642768309
Total Pages : 476 pages
Book Rating : 4.7/5 (683 download)
Download or read book Modern Trends in Human Leukemia IX written by Rolf Neth and published by . This book was released on 1992-10-29 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive account of the most recent trends in human leukemia, as presented at the Ninth Wilsede Meeting. The internationally renowned contributors deal with all different aspects of these diseases: As well as discussing important clinical aspects of leukemia, new information on the biological basis of leukemia gained using the methods of molecular genetics, cell and molecular biology, virology, and immunology is covered. The book shows both the complexity of leukemia research, as well as the value of basic scientific research in furthering clinical medicine and therapy.
Author : Rolf Neth
Publisher : Springer Science & Business Media
ISBN 13 : 3642768296
Total Pages : 518 pages
Book Rating : 4.6/5 (427 download)
Download or read book Modern Trends in Human Leukemia IX written by Rolf Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive account of the most recent trends in human leukemia, as presented at the Ninth Wilsede Meeting. The internationally renowned contributors deal with all different aspects of these diseases: As well as discussing important clinical aspects of leukemia, new information on the biological basis of leukemia gained using the methods of molecular genetics, cell and molecular biology, virology, and immunology is covered. The book shows both the complexity of leukemia research, as well as the value of basic scientific research in furthering clinical medicine and therapy.
Author : Rolf Neth
Publisher : Springer Science & Business Media
ISBN 13 : 3642726240
Total Pages : 563 pages
Book Rating : 4.6/5 (427 download)
Download or read book Modern Trends in Human Leukemia VII written by Rolf Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie, Hamburg, June 27/28, 1986
Author : R. Neth
Publisher : Springer Science & Business Media
ISBN 13 : 364268761X
Total Pages : 539 pages
Book Rating : 4.6/5 (426 download)
Download or read book Modern Trends in Human Leukemia V written by R. Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie, Wilsede, June 21-23, 1982
Author : R. Neth
Publisher : Springer Science & Business Media
ISBN 13 : 3642679846
Total Pages : 574 pages
Book Rating : 4.6/5 (426 download)
Download or read book Modern Trends in Human Leukemia IV written by R. Neth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on behalf of the Deutsche Gesellschaft für Hämatologie und Onkologie. Wilsede, June 21-23, 1982
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1324 pages
Book Rating : 4.:/5 (319 download)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1971 with total page 1324 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. Hagenbeek
Publisher : Springer Science & Business Media
ISBN 13 : 9400942737
Total Pages : 407 pages
Book Rating : 4.4/5 (9 download)
Download or read book Minimal Residual Disease in Acute Leukemia 1986 written by A. Hagenbeek and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relapse of leukemia following successful remission-induction therapy remains a major obstacle in the treatment of patients with acute leukemia. Leukemia recurs most frequently in patients with acute myeloblastic leukemia (AML) and high risk acute lymphoblastic leukemia (ALL) following chemotherapy and less often in patients with low risk ALL and particularly in patient groups> submitted to allogeneic marrow transplantation. ' It is likely that the great majority of these recurrences originate from residual leukemic cells that survive initial remission-induction chemotherapy. Today, several research groups throughout the world place emphasis on studies concerned with the detection and treatment of 'minimal residual disease' (MRD). These investigations are conducted with the common objective to tackle the remaining cells. 'Minimal Residual Disease in Acute Leukemia: 1986' summarizes the fast advancements in this area. Several disciplines are concerned with the analysis of leukemic cells. The perspectives of cytogenetic and molecular genetic approaches for applica tion in the detection of MRD are reviewed. In this respect, modern cyto genetics provide highly specific tumor markers. The resolution of cyto genetic methods can be particularly improved when combined with other techniques which select relevant subpopulations of cells. Characterization of oncogenes and gene rearrangements, including those of immunoglobulin and T-cell receptor genes, and the measurement of gene products, have been established. Techniques based on these approaches offer interesting tools for the detection of MRD. New possibilities of employing monoclonal anti bodies are also presented.
Author : Dieter Huhn
Publisher : Springer Science & Business Media
ISBN 13 : 3642735266
Total Pages : 228 pages
Book Rating : 4.6/5 (427 download)
Download or read book Chronic Myelocytic Leukemia and Interferon written by Dieter Huhn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies on the effect of recombinant human interferon (rIFN) on the growth of colonies of multi potential hematopoietic progenitors have demonstrated that IFN inhibits the growth of these cells in culture. The inhibitory effect of IFN was more pronounced in multilineage colony forming cells (CFU-GEMMT) of marrow cells of patients with chronic myelogenous leukemia (CML) compared with stern cells of normal marrow. T cell colony formation (CFU-TL) of phi_positive T cells obtained from primary multilineage hematopoietic colonies was inhibited by rIFN. Inhibition of T cell colony formation of Phi T cells was more profound by IFN compared with secondary T cells of healthy individuals. Southern blot analysis of secondary T cells from normal individuals revealed a germ line pattern when examined for T cell receptor (TcR) gene re arrangements using the cDNA of the beta chain. Subcloned Phi T cells of one patient with CML demonstrated gene rearrangements of the TcR. We also demonstrated the disappearance of phi_positive multilineage hematopoietic colonies when marrow cells were preincubated with IFN and subsequently cultured in the presence of IFN. The cytoconversion of the Phi chromosome in metaphases obtained from individually analyzed multilineage hematopoietic colonies suggests that IFN might allow the restoration of nonclonal hematopoiesis in patients with CML. Acknowledgement. Supported in part by Deutsche Forschungsgemeinschaft and the Medical Research Council of Canada. References 1. Koeffler HP, Golde DW (1981) Chronic myelogenous 1eukelnia - new concepts.
Author : Ajay Vora
Publisher : Springer
ISBN 13 : 3319397087
Total Pages : 342 pages
Book Rating : 4.3/5 (193 download)
Download or read book Childhood Acute Lymphoblastic Leukemia written by Ajay Vora and published by Springer. This book was released on 2017-04-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author : M. F. Greaves
Publisher : Elsevier
ISBN 13 : 1483151034
Total Pages : 179 pages
Book Rating : 4.4/5 (831 download)
Download or read book Epidemiology of Leukaemia and Lymphoma written by M. F. Greaves and published by Elsevier. This book was released on 2013-10-22 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Leukaemia and Lymphoma contains the proceedings of the Leukaemia Research Fund International Workshop held in Oxford, UK, on September 25-27, 1984. Contributors explore the epidemiology of leukemia and lymphoma based on the results of a pilot study that investigated whether careful subdivision of acute lymphoblastic leukemia (ALL) using a standardized panel of monoclonal antibodies would reveal interesting associations between subtypes and particular geographic regions or ethnic groups within regions. This book is comprised of 31 chapters divided into four sections and begins with a discussion on epidemiological approaches to hematological malignancy, paying particular attention to international data collection and interpretation; clusters and associations in cancer epidemiology; and childhood leukemia in Great Britain and the Netherlands. The next section explores the causes of human leukemia and lymphoma as well as the epidemiology of leukemia and lymphoma subtypes in various regions of the world such as Africa, Asia, United States, and Mediterranean region. The final section focuses on practical problems in standardized immunophenotyping of leukemias and lymphomas; immuno-alkaline phosphatase labeling of hematological samples; and detection of surface membrane antigens by a rosette assay using antibody coupled red cells. This monograph will be of value to clinicians and medical practitioners interested in the epidemiology of leukemia and lymphoma.
