Mobilizing Mutations

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022663809X
Total Pages : 409 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Mobilizing Mutations by : Daniel Navon

Download or read book Mobilizing Mutations written by Daniel Navon and published by University of Chicago Press. This book was released on 2019-09-20 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

Mobilizing Mutations

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022663812X
Total Pages : 409 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Mobilizing Mutations by : Daniel Navon

Download or read book Mobilizing Mutations written by Daniel Navon and published by University of Chicago Press. This book was released on 2019-09-20 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

All God's Mistakes

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Publisher : University of Chicago Press
ISBN 13 : 9780226066820
Total Pages : 228 pages
Book Rating : 4.0/5 (668 download)

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Book Synopsis All God's Mistakes by : Charles L. Bosk

Download or read book All God's Mistakes written by Charles L. Bosk and published by University of Chicago Press. This book was released on 1995-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: In one case after another, Charles L. Bosk reveals the process by which parents, physicians and other health professionals come to guide decisions about pregnancies. A story of both extraordinary drama and ordinary routine, this is a pioneering case study of authority and control in a pediatric hospital, showing how genetic counselors work with colleagues and with parents to be, and how they deal with their powerlessness to control life-and-death decisions that they must address.

Mobilizing Others

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Author :
Publisher : John Benjamins Publishing Company
ISBN 13 : 902726158X
Total Pages : 293 pages
Book Rating : 4.0/5 (272 download)

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Book Synopsis Mobilizing Others by : Carmen Taleghani-Nikazm

Download or read book Mobilizing Others written by Carmen Taleghani-Nikazm and published by John Benjamins Publishing Company. This book was released on 2020-05-15 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Requesting, recruitment, and other ways of mobilizing others to act have garnered much interest in Conversation Analysis and Interactional Linguistics. This volume takes a holistic perspective on the practices that we use to get others to act either with us, or for us. It argues for a more explicit focus on ‘activity’ in unpacking the linguistic and embodied choices we make in designing mobilizing moves. Drawing on studies from a variety of different languages and settings, the collected studies in this volume illustrate how interactants design their turns not only for specific recipients, but also for a specific interactional situation. In doing so, speakers are able to mobilize others’ cooperation, contribution, or assistance in the most appropriate and economical ways. By focusing on ‘situation design’ across languages and settings, this volume provides new insights into the ways in which the ongoing activity, with its attendant participation structures, shapes the design, placement, and understanding of moves which mobilize others to act.

The Immigrant Rights Movement

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Publisher : Stanford University Press
ISBN 13 : 1503609332
Total Pages : 387 pages
Book Rating : 4.5/5 (36 download)

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Book Synopsis The Immigrant Rights Movement by : Walter J. Nicholls

Download or read book The Immigrant Rights Movement written by Walter J. Nicholls and published by Stanford University Press. This book was released on 2019-08-13 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the months leading up to the 2016 presidential election, liberal outcry over ethnonationalist views promoted a vision of America as a nation of immigrants. Given the pervasiveness of this rhetoric, it can be easy to overlook the fact that the immigrant rights movement began in the US relatively recently. This book tells the story of its grassroots origins, through its meteoric rise to the national stage. Starting in the 1990s, the immigrant rights movement slowly cohered over the demand for comprehensive federal reform of immigration policy. Activists called for a new framework of citizenship, arguing that immigrants deserved legal status based on their strong affiliation with American values. During the Obama administration, leaders were granted unprecedented political access and millions of dollars in support. The national spotlight, however, came with unforeseen pressures—growing inequalities between factions and restrictions on challenging mainstream views. Such tradeoffs eventually shattered the united front. The Immigrant Rights Movement tells the story of a vibrant movement to change the meaning of national citizenship, that ultimately became enmeshed in the system that it sought to transform.

The Politics of Pain Medicine

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Publisher : University of Chicago Press
ISBN 13 : 022626405X
Total Pages : 253 pages
Book Rating : 4.2/5 (262 download)

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Book Synopsis The Politics of Pain Medicine by : S. Scott Graham

Download or read book The Politics of Pain Medicine written by S. Scott Graham and published by University of Chicago Press. This book was released on 2015-11-17 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author explores the changing rhetoric of pain medicine and how this rhetoric ultimately shapes the health-care community's understanding of what pain medicine is, how the medicine should be practiced and regulated, and how practitioner-patient relationships are best managed. -- Dust jacket.

Disease Control Priorities, Third Edition (Volume 6)

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Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

After the Internet

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Publisher : MIT Press
ISBN 13 : 1635901685
Total Pages : 217 pages
Book Rating : 4.6/5 (359 download)

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Book Synopsis After the Internet by : Tiziana Terranova

Download or read book After the Internet written by Tiziana Terranova and published by MIT Press. This book was released on 2022-12-13 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the internet's transformation from communication tool to computational infrastructure. The internet is no more. If it still exists, it does so only as a residual technology, still effective in the present but less intelligible as such. After nearly two decades and a couple of financial crises, it has become the almost imperceptible background of today’s Corporate Platform Complex (CPC)—a pervasive planetary technological infrastructure that meshes communication with computation. In the essays collected in this book, written mostly between the mid-2000s and the late 2010s, Tiziana Terranova bears witness to this monstrous transformation. Mobilizing theories of cognitive capitalism, neo-monadology, and sympathetic cooperation, considering ideas such as the attention economy and its psychopathologies, and evoking the relation between algorithmic automation and the Common, she provides real-time takes on the mutations that have changed the technological, cultural, and economic ethos of the Internet. Mostly conceived, elaborated, and discussed in collective activist spaces, After the Internet is neither apocalyptic lamentation nor melancholic “rise and fall” story of betrayed great expectations. On the contrary, it looks within the folds of the recent past to unfold the potential futurities that the post-digital computational present still entails.

The Mobilization of Shame

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Author :
Publisher : Yale University Press
ISBN 13 : 9780300093193
Total Pages : 260 pages
Book Rating : 4.0/5 (931 download)

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Book Synopsis The Mobilization of Shame by : Robert F. Drinan

Download or read book The Mobilization of Shame written by Robert F. Drinan and published by Yale University Press. This book was released on 2001-01-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: 13 The Right to Food

Inclusion

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Author :
Publisher : ReadHowYouWant.com
ISBN 13 : 1459606027
Total Pages : 430 pages
Book Rating : 4.4/5 (596 download)

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Book Synopsis Inclusion by : Steven Epstein

Download or read book Inclusion written by Steven Epstein and published by ReadHowYouWant.com. This book was released on 2010-10 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Inclusion, Steven Epstein argues that strategies to achieve diversity in medical research mask deeper problems, ones that might require a different approach and different solutions. Formal concern with this issue, Epstein shows, is a fairly recent phenomenon. Until the mid-1980s, scientists often studied groups of white, middle-aged men - and assumed that conclusions drawn from studying them would apply to the rest of the population. But struggles involving advocacy groups, experts, and Congress led to reforms that forced researchers to diversify the population from which they drew for clinical research. While the prominence of these inclusive practices has offered hope to traditionally underserved groups, Epstein argues that it has drawn attention away from the tremendous inequalities in health that are rooted not in biology but in society. This edition is in two volumes. The second volume ISBN is 9781458732194.

Mobilizing Mutations

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022663809X
Total Pages : 409 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis Mobilizing Mutations by : Daniel Navon

Download or read book Mobilizing Mutations written by Daniel Navon and published by University of Chicago Press. This book was released on 2019-09-20 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation. But what does this mean for the way we understand a person? Today, genetic mutations are being used to diagnose novel conditions like the XYY, Fragile X, NGLY1 mutation, and 22q11.2 Deletion syndromes, carving out rich new categories of human disease and difference. Daniel Navon calls this form of categorization “genomic designation,” and in Mobilizing Mutations he shows how mutations, and the social factors that surround them, are reshaping human classification. Drawing on a wealth of fieldwork and historical material, Navon presents a sociological account of the ways genetic mutations have been mobilized and transformed in the sixty years since it became possible to see abnormal human genomes, providing a new vista onto the myriad ways contemporary genetic testing can transform people’s lives. Taking us inside these shifting worlds of research and advocacy over the last half century, Navon reveals the ways in which knowledge about genetic mutations can redefine what it means to be ill, different, and ultimately, human.

Biology and Engineering of Stem Cell Niches

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Author :
Publisher : Academic Press
ISBN 13 : 0128027568
Total Pages : 644 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biology and Engineering of Stem Cell Niches by : Ajaykumar Vishwakarma

Download or read book Biology and Engineering of Stem Cell Niches written by Ajaykumar Vishwakarma and published by Academic Press. This book was released on 2017-03-22 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type. - Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system - Authored and edited by authorities in this emerging and multidisciplinary field - Includes valuable links to 5-10 minute YouTube© author videos that describe main points

Genetic Analysis of Complex Disease

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Publisher : John Wiley & Sons
ISBN 13 : 1119104076
Total Pages : 340 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Genetic Analysis of Complex Disease by : William K. Scott

Download or read book Genetic Analysis of Complex Disease written by William K. Scott and published by John Wiley & Sons. This book was released on 2021-11-11 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Analysis of Complex Diseases An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies. This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues. Genetic Analysis of Complex Diseases also provides: A thorough introduction to study design for the identification of genes in complex traits Comprehensive explorations of basic concepts in genetics, disease phenotype definition and the determination of the genetic components of disease Practical discussions of modern bioinformatics tools for analysis of genetic data Reflecting on responsible conduct of research in genetic studies, as well as linkage analysis and data management New expanded chapter on complex genetic interactions This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.

The For the War Yet to Come

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Publisher : Stanford University Press
ISBN 13 : 1503605612
Total Pages : 264 pages
Book Rating : 4.5/5 (36 download)

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Book Synopsis The For the War Yet to Come by : Hiba Bou Akar

Download or read book The For the War Yet to Come written by Hiba Bou Akar and published by Stanford University Press. This book was released on 2018-09-11 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Through elegant ethnography and nuanced theorization . . . gives us a new way of thinking about violence, development, modernity, and ultimately, the city.” —Ananya Roy, University of California, Los Angeles Beirut is a city divided. Following the Green Line of the civil war, dividing the Christian east and the Muslim west, today hundreds of such lines dissect the city. For the residents of Beirut, urban planning could hold promise: a new spatial order could bring a peaceful future. But with unclear state structures and outsourced public processes, urban planning has instead become a contest between religious-political organizations and profit-seeking developers. Neighborhoods reproduce poverty, displacement, and urban violence. For the War Yet to Come examines urban planning in three neighborhoods of Beirut’s southeastern peripheries, revealing how these areas have been developed into frontiers of a continuing sectarian order. Hiba Bou Akar argues these neighborhoods are arranged, not in the expectation of a bright future, but according to the logic of “the war yet to come”: urban planning plays on fears and differences, rumors of war, and paramilitary strategies to organize everyday life. As she shows, war in times of peace is not fought with tanks, artillery, and rifles, but involves a more mundane territorial contest for land and apartment sales, zoning and planning regulations, and infrastructure projects. Winner of the Anthony Leeds Prize “Upends our conventional notions of center and periphery, of local and transnational, even of war and peace.” —AbdouMaliq Simone, Max Planck Institute for the Study of Religious and Ethnic Diversity “Fascinating, theoretically astute, and empirically rich.” —Asef Bayat, University of Illinois — Urbana-Champaign “An important contribution.” —Christine Mady, International Journal of Middle East Studies

Life Histories of Genetic Disease

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Publisher : Johns Hopkins University Press+ORM
ISBN 13 : 1421420759
Total Pages : 264 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Life Histories of Genetic Disease by : Andrew J. Hogan

Download or read book Life Histories of Genetic Disease written by Andrew J. Hogan and published by Johns Hopkins University Press+ORM. This book was released on 2016-10-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A richly detailed history that “uncovers the challenges and limitations of our increasing reliance on genetic data in medical decision making” (Shobita Parthasarathy, author of Building Genetic Medicine). Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing expectant parents to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In this book, Andrew J. Hogan explores how various diseases were “made genetic” after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly “big data”–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation. Hogan critiques the modern ideology of genetic prevention, which suggests all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies offer whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.

Entrepreneurial Identity in US Book Publishing in the Twenty-First Century

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Author :
Publisher : Cambridge University Press
ISBN 13 : 1108877796
Total Pages : 163 pages
Book Rating : 4.1/5 (88 download)

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Book Synopsis Entrepreneurial Identity in US Book Publishing in the Twenty-First Century by : Rachel Noorda

Download or read book Entrepreneurial Identity in US Book Publishing in the Twenty-First Century written by Rachel Noorda and published by Cambridge University Press. This book was released on 2021-09-23 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Entrepreneurship underpins many roles within the publishing industry, from freelancing to bookselling. Entrepreneurs are shaped by the contexts in which their entrepreneurship is situated (social, political, economic, and national). Additionally, entrepreneurship is integral to occupational identity for book publishing entrepreneurs. This Element examines entrepreneurship through the lens of identity and narrative based on interview data with book publishing entrepreneurs in the US Book publishing entrepreneurship narratives of independence, culture over commerce, accidental profession, place, risk, (in)stability, busyness, and freedom are examined in this Element.

Human Geopolitics

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Publisher : Oxford University Press
ISBN 13 : 0192569988
Total Pages : 350 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Human Geopolitics by : Alan Gamlen

Download or read book Human Geopolitics written by Alan Gamlen and published by Oxford University Press. This book was released on 2019-05-02 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human geopolitics, the competition for population rather than territory, is an essential but weakly understood dimension of world politics today. Such competition has preceded violent conflict throughout history, but has been muted since the Treaties of Westphalia laid the territorial foundations of the modern international system in the mid-seventeenth century. Today, however, human geopolitics is being resurrected in unanticipated ways, as governments are enabled and encouraged to engage their emigrant diasporas. How and why is this happening? Until now these questions have been difficult to answer. The majority of research attention has focused on questions of immigration policy in a handful of wealthy migrant destination countries, largely ignoring the emigration policies that preoccupy the worlds many migrant origin states. This book addresses that research imbalance, by focusing on the overlooked sending side of migration policy. Drawing on data covering all UN members across the post-WWII period, and fieldwork with high-level policy makers across 60 states and a dozen international organisations, the book charts the re-emergence of human geopolitics through the global spread of diaspora institutions government ministries and offices dedicated to emigrants and their descendants. It calls for the development of stronger guiding principles and evaluation frameworks to govern these new state-diaspora relations in an era of unprecedented global interdependence.