Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Mitochondrial Pathology In Neuromuscular Diseases full books in PDF, epub, and Kindle. Read online Mitochondrial Pathology In Neuromuscular Diseases ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author : G. Scarlato
Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.5/5 (883 download)
Download or read book Mitochondrial Pathology in Muscle Diseases written by G. Scarlato and published by . This book was released on 1983 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mitochondrial Pathology in Neuromuscular Diseases written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Anthony H.V. Schapira
Publisher : Butterworth-Heinemann
ISBN 13 : 1483193691
Total Pages : 265 pages
Book Rating : 4.4/5 (831 download)
Download or read book Mitochondrial Disorders in Neurology written by Anthony H.V. Schapira and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome oxidase deficiency; use of tissue culture in the diagnosis of mitochondrial disease; and advances in mitochondrial genetics. This publication is a good source for clinicians and students concerned with the defective mitochondrial function.
Author : Claude Desnuelle
Publisher : Springer Science & Business Media
ISBN 13 : 2817809297
Total Pages : 314 pages
Book Rating : 4.8/5 (178 download)
Download or read book Mitochondrial Disorders written by Claude Desnuelle and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of mitochondrial diseases originated in 1962 with the description by Luft and coworkers of a patient with nonthyroidal hypermetabolism due to loose coupling of oxidation and phosphorylation in muscle mitochondria. Over the following quarter of a century, thanks to W. King Engel's "ragged-red fibres" as convenient markers for mitochondrial pathology, numerous papers described clinical, morphological, and biochemical features of "mitochondrial myopathies." In 1988 the discovery of mutations in mitochondrial DNA led to an explosive expansion of research into mitochondrial disorders. Throughout the 1990s the rapid identification of multiple mitochondrial gene defects associated with clinically diverse disorders has left practitioners puzzled about diagnosing such heterogeneous and complex syndromes. Through updated data, this book discusses now what Luft aptly called "mitochondrial medicine." In so doing, it considers the pivotal role of mitochondria in drug sensitivity, their key roles in ageing, apoptosis, and neurodegeneration along with primary mitochondrial diseases due to mutations in the nuclear genome, in the mitochondrial genome, or in the cross-talk between the two genomes.
Author : Anthony Henry Vernon Schapira
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.3/5 (91 download)
Download or read book Mitochondrial Disorders in Neurology 2 written by Anthony Henry Vernon Schapira and published by Butterworth-Heinemann. This book was released on 2002 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain practical explanations of the science underlying mitochondrial disorders in neurology. Written by leading experts, this new Blue Book helps you recognize and manage the diseases. Includes: Sections on the role of mitochondria in neurodegenerative disease The development of animal models for mitochondrial diseases The design of treatments for patients with mitochondrial defects
Author : Lan Zhou
Publisher : Springer Nature
ISBN 13 : 3030256820
Total Pages : 408 pages
Book Rating : 4.0/5 (32 download)
Download or read book A Case-Based Guide to Neuromuscular Pathology written by Lan Zhou and published by Springer Nature. This book was released on 2019-10-24 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical guide to the field of neuromuscular pathology including muscle, peripheral nerve, and skin biopsies with biopsy interpretation. Divided into three parts, the book begins with introductory chapters that review muscle, nerve, and skin biopsy indications and procedures, normal muscle and nerve histology, and common muscle and nerve pathology. The 28 myopathy case chapters in Part 2 and 11 neuropathy case chapters in Part 3 illustrate the clinical and pathological features of many neuromuscular diseases, demonstrate the indications and utilities of biopsies, discuss clinical and pathological differential diagnosis, update the individual disease management, and summarize pertinent clinical and pathology pearls for each case. A Case-Based Guide to Neuromuscular Pathology will function as an indispensable reference for neurologists and pathologists looking to understand the utility of muscle, nerve, and skin biopsies. This book will also aid neurology residents, neuromuscular fellows and neuropathology fellows in preparing for questions related to the muscle and nerve pathology in their in-service and board exams.
Author : Maher Kurdi
Publisher : CRC Press
ISBN 13 : 1000346552
Total Pages : 238 pages
Book Rating : 4.0/5 (3 download)
Download or read book Neuromuscular Pathology Made Easy written by Maher Kurdi and published by CRC Press. This book was released on 2021-03-18 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of Neuromuscular Pathology continuous to expand, as evidenced by the numerous multivolume and speciality texts published in recent years. This short textbook provides a complete overview of both clinical and histological aspects of common and rare neuromuscular diseases. The objective is twofold: to provide information about neuromuscular diseases in a simplified, integrated, and rapidly accessible format suited to those initially encountering the discipline, and also to provide a clear approach using simple pictures, tables and algorithms to illustrate histological features in muscle and nerve biopsy. This volume is conveniently divided into three sections with a total of 30 chapters. The first section deals with basic principles of neuromuscular histology and physiology, processing technique, histochemistry, and laboratory management. The second and third sections deal with neuromuscular diseases that are summarized in a stepwise approach, complemented by algorithms and organized tables. A simplified, integrated, and rapidly accessible format covering both common and rare neuromuscular diseases Clear simple illustrations, organized tables and algorithms to aid the reader in finding an easy approach to accurate diagnosis Practical tips to facilitate histopathological diagnosis. Clinical scenarios discussing common neuromuscular conditions Neurologists, neuropathologists, trainees and medical students involved in clinical neuroscience and pathology will find this guide of practical benefit in both education and practice.
Author : Hans H. Goebel
Publisher : John Wiley & Sons
ISBN 13 : 1118635485
Total Pages : 731 pages
Book Rating : 4.1/5 (186 download)
Download or read book Muscle Disease written by Hans H. Goebel and published by John Wiley & Sons. This book was released on 2013-05-29 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by more than 60 international experts in the field, Muscle Disease embodies the explosion of new concepts and information on the pathology and genetics of muscle disease that has occurred in recent years. In order to accommodate the new complex principles involved, the book is organized around the motor unit and the inherited disorders, in particular, are centered on the ultrastructure and organelles within the muscle fiber. In this way, the wide spectrum of muscle diseases, ranging from neurogenic and inflammatory disorders to those involving defects in a single gene, can be expressed in a logical sequence. For example, disorders that principally involve specific organelles or particular metabolic processes are grouped together, with sections on disorders of the sarcolemma, mitochondria, myofibrils, glycogen and lipid metabolism, etc. Firm reference to clinical aspects and classification of muscle diseases has been maintained throughout the book with an initial clinical overview and with specific clinical sections in each chapter. For ease of navigation through the complex variety of muscle diseases, each chapter has been organized in a standard pattern that allows the reader to easily locate information on individual disease entities in different chapters. This new edition of Muscle Disease: Pathology and Genetics will be a very valuable resource for clinicians, pathologists, geneticists and basic neuroscientists involved in diagnosis, research, treatment and management of patients with muscle disease.
Author : András L. Korényi-Both
Publisher : Charles C. Thomas Publisher
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.3/5 (91 download)
Download or read book Muscle Pathology in Neuromuscular Disease written by András L. Korényi-Both and published by Charles C. Thomas Publisher. This book was released on 1983 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J. Bethlem
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.3/5 (91 download)
Download or read book Neuromuscular Diseases written by J. Bethlem and published by . This book was released on 1987 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for physicians and other practitioners, this book provides clear, up-to-date information on all important neuromuscular diseases, with concise yet complete descriptions of the clinical signs and symptoms. Each chapter reviews laboratory findings, creatine kinase activity, electronmyography, enzyme histochemistry, and electromicroscopy or computed tomography of the muscles and offers detailed descriptions of the various patient complaints and clinical findings on examination. Special attention has been paid to testing procedures and the many possibilities for treatment, with useful tables for grading muscle strength and functional activity. Thirty-one tables are included for easy reference and the book contains excellent photographs of the most important signs of neuromuscular disease.
Author : Balan Louis Gaspar
Publisher : Springer
ISBN 13 : 9811314624
Total Pages : 305 pages
Book Rating : 4.8/5 (113 download)
Download or read book Myopathology written by Balan Louis Gaspar and published by Springer. This book was released on 2018-09-24 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of basic, essential, recent advances and controversies in myopathology. The major emphasis is on diagnostic myopathology of muscular dystrophies, inflammatory myopathies, mitochondrial myopathies, metabolic myopathies, congenital myopathies, myopathies of miscellaneous etiology, neurogenic and neuromuscular junction disorders, the goal being to broaden readers’ understanding of individual disease subgroups. The book also contains all the essential details needed to establish a neuromuscular lab, making it especially relevant for laboratory technical staff and research scholars.
Author : Stirling Carpenter
Publisher : New York : Churchill Livingstone
ISBN 13 :
Total Pages : 812 pages
Book Rating : 4.3/5 (91 download)
Download or read book Pathology of Skeletal Muscle written by Stirling Carpenter and published by New York : Churchill Livingstone. This book was released on 1984 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has been described as the bible of muscle disease, from both a scientific and a clinical point of view. It is a comprehensive work that explains and illustrates in detail all pathological reactions of skeletal muscles that occur in human disease. The microscopic changes are illustrated by histochemistry, immunocytochemistry, resin histology, and electron microscopy. The pathological findings are correlated with the clinical picture whenever possible. The interpretation of the findings is scientifically based. To facilitate this process, the fundamentals of normal histology and biology of the muscle cell are also covered.The book has been thoroughly revised and expanded for this Second Edition to provide up-to-date coverage of the relevant molecular biology and molecular genetics, as well as extensive references. It has been well organized and richly illustrated by the authors, who have been at the forefront of muscle pathology and neuromuscular research for 35 years. This practical reference work is intended for neuropathologists, neurologists, and general pathologists who look at muscle biopsies. It will also serve as an introduction to muscle disease for neurology and pathology residents.
Author : Patrick Lestienne
Publisher : Springer Science & Business Media
ISBN 13 : 3642598846
Total Pages : 397 pages
Book Rating : 4.6/5 (425 download)
Download or read book Mitochondrial Diseases written by Patrick Lestienne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: For those like me who witnessed the beginning of the adventure of human mitochon drial pathology, one can only be astounded by the extent and unexpectedness of what the field has come to offer. Extent because nobody could have imagined the sheer size of the domain. Unexpectedness because hitherto it was impossible to imagine the clinical polymorphism that this pathology would represent. The starting point was clear. Initially, there was the exceptional, and for a long time unique, observation of euthyroidian hypermetabolism that Luft and colleagues analyzed remarkably in biochemical and clinical terms. Thereafter, there was the support provided by the electron microscopy studies of Afzelius, and the very first visualization of mitochondrial abnormalities. That was way back in 1958. A few years later, progress in the cytology and cytochemistry of skeletal muscle tissue was to provide the means of detecting such abnormalities by examining sections with light microscopy. The colorful term "ragged red fibers", coined by W. K. Engel, became uni versally accepted, and this typical aspect with Gomori trichrome stain was to throw light on the frequency with which these mitochondrial abnormalities could occur under pathological conditions which, until then, had remained a total mystery regard ing their mechanism: syndromes such as the ocular myopathies with their descending evolution and the oculocraniosomatic syndromes. We were at the beginning of the 1970s.
Author : Michael Swash
Publisher : Springer Science & Business Media
ISBN 13 : 1447138341
Total Pages : 548 pages
Book Rating : 4.4/5 (471 download)
Download or read book Neuromuscular Diseases written by Michael Swash and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.
Author : Gulden Diniz
Publisher : Springer Nature
ISBN 13 : 303133924X
Total Pages : 362 pages
Book Rating : 4.0/5 (313 download)
Download or read book Clues for Differential Diagnosis of Neuromuscular Disorders written by Gulden Diniz and published by Springer Nature. This book was released on 2023-08-22 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book evaluates muscle and nerve biopsies. It creates a more analytical view of neuromuscular diseases in the light of clinical findings. Diseases that occur mostly in muscle or nerve tissue may show common clinical findings. Addressing these two issues together will make it easier to understand the diseases. Neuromuscular diseases, normal histology, embryology, and physiopathology of muscles and nerves are discussed with a main focus on differential diagnosis. The book also presents the most cost-effective and easiest-to-follow algorithms for the differential diagnosis of diseases.
Author : C. P. Lee
Publisher : Academic Press
ISBN 13 : 1483297837
Total Pages : 267 pages
Book Rating : 4.4/5 (832 download)
Download or read book Molecular Basis of Mitochondrial Pathology written by C. P. Lee and published by Academic Press. This book was released on 2014-11-27 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of mitochondrial diseases is currently one of the rapidly growing fields of research in cell and molecular biology. This volume encompasses the latest development in this field of research. The chapters cover topics in a wide range of disciplines including biophysics, biochemistry, cell and molecular biology, molecular genetics, and clinical medicine. Summarizes growing evidence of the role of mitochondria in a large number of pathological conditions Brings together different approaches toward understanding mitochondria diseases Molecular and cellular biology Clinical physiology and medicine Details the crucial role this organelle plays in genetic regulation of various biological functions
Author : Victor Dubowitz
Publisher : Elsevier Health Sciences
ISBN 13 : 0702078581
Total Pages : 549 pages
Book Rating : 4.7/5 (2 download)
Download or read book Muscle Biopsy written by Victor Dubowitz and published by Elsevier Health Sciences. This book was released on 2020-05-28 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than 45 years, Muscle Biopsy: A Practical Approach has offered, comprehensive, clinically-focused coverage of the acquisition, interpretation, and assessment of muscle biopsies – an area often only lightly covered in pathology texts. Taking an integrated approach that includes clinical, genetic, biochemical, and pathological features, the 5th Edition covers the full range of muscle disease in both adults and children. This highly illustrated, easy-to-use volume helps you navigate this challenging area, bridging the gap between clinical syndromes/disorders and their underlying pathologies. Fully updated 5th edition of this internationally acclaimed classic in muscle pathology. Written by internationally recognized world leaders in the field of muscle pathology. Comprehensive coverage of histology, histochemistry, immunocytochemistry and electron microscopy in parallel with clinical and genetic advances. Lavishly illustrated with over 600 full colour images. Fully updated literature review. Comprehensive update on the rapidly expanding field of neuromuscular disorders. 4th edition Highly Commended in Pathology category of the prestigious 2014 BMA Medical Book Awards.
