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Mise En Place Dune Ligne De Production De Seringues Pre Remplies Pour Essais Cliniques
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Book Synopsis Mise en place d'une ligne de production de seringues pré-remplies pour essais cliniques by : Johann Oheix
Download or read book Mise en place d'une ligne de production de seringues pré-remplies pour essais cliniques written by Johann Oheix and published by . This book was released on 2009 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lorsque les laboratoires pharmaceutiques mettent en place des essais cliniques pour un médicament injectable, des essais doivent être réalisés sur la seringue, qui fait partie intégrante du médicament. Les fabricants de systèmes d'administration peuvent réaliser en interne ces essais afin de transmettre aux laboratoires pharmaceutiques, détenteurs des molécules pharmacologiquement actives, des seringues ayant passé l'ensemble des essais qui leurs sont propres. Dans cet objectif, une ligne de fabrication de seringues pré-remplies est installée afin d'effectuer l'étape de mise sous forme pharmaceutique. Dans ce contexte, un processus est mis en place afin d'apporter la preuve que le médicament fabriqué satisfait aux exigences réglementaires et est administrable au patient : il s'agit de la qualification et de la validation, qui sont des éléments de l'assurance de la qualité. La qualification concerne les équipements (remplisseuse, laveur-désinfecteur, scelleuse et autoclave) ainsi que l'environnement dans lesquels ils sont installés (zones à atmosphère contrôlées classe C et classe D), tandis que la validation concerne le procédé dans son ensemble. Un mode de gestion par projet se révèle adapté et très efficace pour ce type d'activité qui fait intervenir de nombreux domaines d'expertise, ce qui nécessite une gestion transversale mettant en jeu différents services (assurance qualité, affaires réglementaires, production, maintenance, contrôle qualité). La gestion du temps et des ressources humaines et matérielles est donc primordiale afin de délivrer un outil de fabrication capable de produire de façon reproductible des seringues pré-remplies répondant aux exigences.
Book Synopsis Comprehensive Cervical Cancer Control by : World Health Organization
Download or read book Comprehensive Cervical Cancer Control written by World Health Organization and published by World Health Organization. This book was released on 2006 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most women who die from cervical cancer, particularly in developing countries, are in the prime of their life. They may be raising children, caring for their family, and contributing to the social and economic life of their town or village. Their death is both a personal tragedy, and a sad and unnecessary loss to their family and their community. Unnecessary, because there is compelling evidence, as this Guide makes clear, that cervical cancer is one of the most preventable and treatable forms of cancer, as long as it is detected early and managed effectively. Unfortunately, the majority of women in developing countries still do not have access to cervical cancer prevention programmes. The consequence is that, often, cervical cancer is not detected until it is too late to be cured. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. It focuses on the knowledge and skills needed by health care providers, at different levels of care.
Book Synopsis Clinical Management of Patients with Viral Haemorrhagic Fever by : World Health Organization
Download or read book Clinical Management of Patients with Viral Haemorrhagic Fever written by World Health Organization and published by World Health Organization. This book was released on 2016-05-03 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".
Book Synopsis World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses by : World Health Organization
Download or read book World Health Organization Guidelines on the Pharmacological Treatment of Persisting Pain in Children with Medical Illnesses written by World Health Organization and published by . This book was released on 2012 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines have been developed to support countries to relieve pain in their paediatric populations. These guidelines address persisting pain in children caused by conditions such as cancer, HIV/AIDS, sickle-cell disease, burns, trauma, and phantom limb pain. Recommendations -- developed following a careful and transparent appraisal of available evidence -- are presented for the pharmacological treatment of mild, moderate and severe pain. The guidelines include chapters on the various systems used to classify pain and on the evaluation of pain, which reviews the available tools for routine pain measurement in children. Provision of sustainable pain relief within health care systems is covered in a separate chapter. Since morphine and other opioid analgesics -- required for the relief of moderate-to-severe pain in children -- are listed under the 1961 UN Single Convention on Narcotic Drugs, the new guidelines include an annex explaining the Convention's requirements for the handling and procurement of opioid analgesics for the relief of pain.
Book Synopsis Cancer Pain Relief by : World Health Organization
Download or read book Cancer Pain Relief written by World Health Organization and published by World Health Organization. This book was released on 1996 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a guide, which introduced a simple, yet highly effective method for the relief of cancer pain. Thoroughly revised and updated, the new edition further refines the WHO method, which advocates the use of a small number of relatively inexpensive drugs, including morphine. Revisions draw on experiences with millions of patients around the world as well as new knowledge about the specific pain syndromes unique to cancer. Completely new are chapters describing the international system by which morphine and other opioids are made available for medical purposes. The book has two parts. Part one provides a practical guide to the relief of cancer pain, concentrating on drug treatment as the mainstay of pain management. The most extensive section sets out detailed guidelines for the selection and prescribing of non-opioid analgesics, opioid analgesics, drugs for neuropathic pain, and adjuvant drugs for the treatment of adverse effects, the enhancement of pain relief and the management of concomitant psychological disturbances. Information ranges from explanations of how specific drugs work, through the precautions to take in the presence of certain disorders, to a list of factors that influence the effectiveness of opioids. Concerning the use of opioids, readers are reminded that psychological dependence does not occur in cancer patients and that the only correct dose of morphine is the one that relieves the pain. Part two provides a guide to opioid availability. A discussion of the reasons why opioids continue to be underprescribed or difficult to obtain is followed by an explanation of the Single Convention on Narcotic Drugs.
Book Synopsis Iheoma My Dear by : Gloria Ernest Samuel
Download or read book Iheoma My Dear written by Gloria Ernest Samuel and published by . This book was released on 2016 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Vulnerability to Drug Abuse by : Meyer Glantz
Download or read book Vulnerability to Drug Abuse written by Meyer Glantz and published by Amer Psychological Assn. This book was released on 1992 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text offers insights into the complex and disturbing questions of drug abuse by examining the range of factors that affect vulnerability, focusing specifically on factors and patterns associated with the transition from drug use to drug abuse.
Download or read book We Created Chávez written by Geo Maher and published by Duke University Press. This book was released on 2013-04-17 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since being elected president in 1998, Hugo Chávez has become the face of contemporary Venezuela and, more broadly, anticapitalist revolution. George Ciccariello-Maher contends that this focus on Chávez has obscured the inner dynamics and historical development of the country’s Bolivarian Revolution. In We Created Chávez, by examining social movements and revolutionary groups active before and during the Chávez era, Ciccariello-Maher provides a broader, more nuanced account of Chávez’s rise to power and the years of activism that preceded it. Based on interviews with grassroots organizers, former guerrillas, members of neighborhood militias, and government officials, Ciccariello-Maher presents a new history of Venezuelan political activism, one told from below. Led by leftist guerrillas, women, Afro-Venezuelans, indigenous people, and students, the social movements he discusses have been struggling against corruption and repression since 1958. Ciccariello-Maher pays particular attention to the dynamic interplay between the Chávez government, revolutionary social movements, and the Venezuelan people, recasting the Bolivarian Revolution as a long-term and multifaceted process of political transformation.
Book Synopsis The European Respiratory Journal by :
Download or read book The European Respiratory Journal written by and published by . This book was released on 1993 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Animal Health: General principles by : Archie Hunter
Download or read book Animal Health: General principles written by Archie Hunter and published by CTA; MacMillan. This book was released on 1996 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Health Volume 1 is a practical guide for anyone involved with maintaining and establishing the health of animals in tropical and sub-tropical regions. It comprehensively explains the causes of animal diseases, how they spread and the means available for their control. The handbook should be used in conjunction with Volume 2: Specific Diseases which is already published.
Book Synopsis Cervical Cancer Screening in Developing Countries by : World Health Organization
Download or read book Cervical Cancer Screening in Developing Countries written by World Health Organization and published by World Health Organization. This book was released on 2002 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cervical cancer is the second most common cancer among women worldwide, with 80 per cent of deaths occurring in developing countries. It is an important area for cancer control programmes because of the burden of the disease and the potential for effective prevention via screening. This publication is based on a comprehensive consultation undertaken by WHO in 2001, involving leading experts in the field of cancer epidemiology, screening and treatment. It focuses on the current situation in low and middle income countries, discusses the efficacy of screening methods available, and assesses potential future developments.
Book Synopsis Probiotic Bacteria by : J. Paulo Sousa e Silva
Download or read book Probiotic Bacteria written by J. Paulo Sousa e Silva and published by CRC Press. This book was released on 2014-04-02 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complied by an expert editorial team with noteworthy and remarkable experience, this book covers technological aspects related to probiotics, not only in terms of delivery modes but also in terms of protection technologies. It includes discussions of their therapeutic and physiologic implications and benefits, and provides a contemporary update and a holistic review of the topic. It focuses on the technological aspects of probiotic products, brings together the information needed for their successful development, and examines the international picture regarding regulatory issues.
Book Synopsis Ahfs Drug Information 2020 by : American Society of Health System Pharmacists
Download or read book Ahfs Drug Information 2020 written by American Society of Health System Pharmacists and published by . This book was released on 2020 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pediatric AIDS written by Philip A. Pizzo and published by Lippincott Williams & Wilkins. This book was released on 1998 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recommended in the Brandon/Hill selected list of print books and journals for the small medical library - April 2001 & 2003 The Third Edition of this very popular book offers the most authoritative and comprehensive review of the impact of the HIV disease in infants, children, and adolescents.
Book Synopsis Resilience and Development by : Meyer D. Glantz
Download or read book Resilience and Development written by Meyer D. Glantz and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts review the research on resilience and represent the diverse perspectives and opinions found among both scientists and practitioners in the field. Although the chapters are written to the standards expected by researchers, they are equally useful for program developers and others in applied fields seeking science-based information on the topic. This book is a unique resource in keeping with the growing interest in resilience both in research and interventions.
Book Synopsis Epidemiologic Trends in Drug Abuse, December 2001: Proceedings of the Community Epidemiology Work Group by :
Download or read book Epidemiologic Trends in Drug Abuse, December 2001: Proceedings of the Community Epidemiology Work Group written by and published by . This book was released on 2002 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brill's Companion to Greek and Latin Pastoral by : Marco Fantuzzi
Download or read book Brill's Companion to Greek and Latin Pastoral written by Marco Fantuzzi and published by BRILL. This book was released on 2006-06-01 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprises articles by an international team of twenty-three scholars. The contributions focus on the historical genesis, stylistic and narrative features and evolution of pastoral, both as genre and mode, from Theocritus to the Byzantine period. Special attention has been paid to the idea of the 'invention of a fictionalized tradition', and to pastoral’s thematic and formal relationship with other literary genres. In their totality, the contributions, as well as offering a comprehensive overview of the more or less familiar issues and ideas discussed in connection with pastoral, point to new emphases, trends and insights in current scholarly work in this area. The volume is addressed to a wide range of students and scholars in classics, but much in it will also be of interest to those working in the fields of comparative and modern literatures.
