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Author : Yue-Hwa Pan Lee
Publisher :
ISBN 13 :
Total Pages : 284 pages
Book Rating : 4.:/5 (27 download)
Download or read book Milk Protein Expression in Mouse Mammary Epithelial Cells written by Yue-Hwa Pan Lee and published by . This book was released on 1984 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Leslie MacKenzie Blackie
Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.:/5 (33 download)
Download or read book The Heterogeneity of Expression of Basement Membrane Componets and Milk Proteins in the Mouse Mammary Gland During Pregnancy written by Leslie MacKenzie Blackie and published by . This book was released on 1992 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jumpei Enami
Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (27 download)
Download or read book Hormonal Control of Milk Protein Synthesis in Mouse Mammary Epithelial Cells in Vitro written by Jumpei Enami and published by . This book was released on 1977 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : C.H. Knight
Publisher : Springer Science & Business Media
ISBN 13 : 146151973X
Total Pages : 296 pages
Book Rating : 4.4/5 (615 download)
Download or read book Intercellular Signalling in the Mammary Gland written by C.H. Knight and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: All being done, we went to Mrs Shipmans, who is a great butter-woman; and I did see there the most of milke and cream, and the cleanest, that I ever saw in my life (29 May 1661). Among others, Sir Wm. Petty did tell me that in good earnest, he hath in his will left such parts of his estate to him that could invent such and such things -as among others, that could discover truly the way of milk coming into the breasts of a woman ... (22 March 1665). My wife tells me that she hears that my poor aunt James hath had her breast cut off here in tow- her breast having long been out of order (5 May 1665). From the Diary of Samuel Pepys, published as The Shorter Pepys (edited by R. Latham), Penguin Books (1987) The long-standing ultimate importance of research on the mammary gland is illustrated by the importance attached to cows' milk for human consumption, to human lactation and to breast cancer by Samuel Pepys and his contemporaries in the middle of the 17th century. Research has tended to develop in isolation in these three areas of continuing contemporary importance largely because in most countries, the underlying science of agricultural productivity is funded separately from the underlying science of human health and welfare.
Author : Li-How Chen
Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.:/5 (7 download)
Download or read book Regulation of Milk Protein Gene Expression by Extracellular Matrix written by Li-How Chen and published by . This book was released on 1989 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author : Caroleen Jakelyn Baker
Publisher :
ISBN 13 :
Total Pages : 106 pages
Book Rating : 4.:/5 (51 download)
Download or read book TGF-[beta] Regulation of Whey Acidic Protein Expression in the Mouse Mammary Gland written by Caroleen Jakelyn Baker and published by . This book was released on 1993 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michelle Elizabeth Rennison
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (61 download)
Download or read book Investigation Into the Control of Milk Protein Secretion from Mouse Mammary Epithelial Cells written by Michelle Elizabeth Rennison and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jack Martinet
Publisher : Editions Quae
ISBN 13 : 2738008615
Total Pages : 692 pages
Book Rating : 4.7/5 (38 download)
Download or read book Biology of Lactation written by Jack Martinet and published by Editions Quae. This book was released on 1999 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: A presentation of the most fundamental features of the biology of the mammary gland, a unique model of an organ capable of an abundant synthesis of proteins: endocrinology of lactation, role of prolactin, genetics and protein synthesis, immunology and the mammary gland, nutrition and dairy products. Readership: students, teachers, researchers, health and agriculture professionals. Lactation Biology was first published in French in 1993. The English version is not merely a translation: it has been updated by the author.
Author : Yanchu Fang
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.:/5 (89 download)
Download or read book Lactogenic Hormone Regulation of Epidermal Growth Factor Gene Expression in Mouse Mammary Epithelial Cells written by Yanchu Fang and published by . This book was released on 1997 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Elizabeth Wellberg
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)
Download or read book Regulation of Mammary Lactogenic Differentiation by Singleminded-2s written by Elizabeth Wellberg and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Sim2s is a basic helix-loop-helix Per-Arnt-Sim (bHLH-PAS) transcription factor. In Drosophila, the Sim2 homolog, sim, is necessary for cell fate determination during central nervous system (CNS) development. In mammals, both Sim2 isoforms are involved in development of various tissues, including muscle, cartilage, and mammary gland. Loss-of-function studies revealed a role for Sim2s in specifying epithelial cell fate during mammary development and inhibiting growth and invasion of aggressive breast cancer cells. This study determined the role of Sim2s in mammary epithelial cell differentiation. Our hypothesis is that Sim2s is sufficient to promote lactogenic differentiation in vivo, characterized by expression of lactation-specific genes. Two models were used to test this hypothesis: (1) a transgenic mouse, expressing Sim2s under control of the MMTV-LTR, and (2) the mouse mammary epithelial cell line HC11. Together, these models allow analysis of the effect of Sim2s on global mammary gland differentiation and the mechanism through which it accomplishes this in a relatively homogenous population of cells. We determined that precocious expression of Sim2s in vivo is associated with upregulation of a subset of milk protein genes in nulliparous females. During early pregnancy, Sim2s regulation of lactogenic differentiation extended to a larger group of genes. Following pup removal, Sim2s appears to promote survival of alveolar epithelial cells. In vitro, Sim2s expression is necessary for maximal Csn2 expression, as determined by loss-of-function studies. Overexpression of Sim2s is sufficient to enhance prolactin-mediated Csn2 expression. Chromatin immunoprecipitation assays performed in HC11 cells revealed enhanced recruitment of Stat5a and RNA Polymerase II (RNAPII) to the regulatory region of Csn2 in the presence of Sim2s. In addition, Sim2s and RNAPII were found in a complex that was localized to both the promoter and coding region of the Csn2 gene. These studies support the idea that Sim2s is upregulated in a developmental stage-specific manner in the mouse mammary gland to promote the survival and differentiation of alveolar epithelial cells expressing high levels of milk protein genes. Further, Sim2s may regulate the function of a specific subset of alveolar cells by targeting the RNAPII holoenzyme complex to genes expressed during lactogenic differentiation.
Author : Isabel Gigli
Publisher : BoD – Books on Demand
ISBN 13 : 9535131370
Total Pages : 92 pages
Book Rating : 4.5/5 (351 download)
Download or read book Current Topics in Lactation written by Isabel Gigli and published by BoD – Books on Demand. This book was released on 2017-05-10 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lactation is a fascinating process. Research over the last decade has provided new insights into the regulation of mammary gland development and involution. Lactation is the last step in reproduction, and therefore it is linked to reproduction strategy. Photoperiod species such as sheep, or pseudo-ovulatory (at mid-gestation) species as the rodent Lagostomus maximus, are interesting and unique models to study mammary gland physiology. This book also offers updated insights into the mechanisms that control postlactational involution, therefore also providing information to better understand breast cancer. Small noncoding RNA has opened new understanding in gene regulation. In this regard, our knowledge of mammary gland development and milk secretion has increased extremely. This book provides current scientific information on all these interesting topics. It will certainly be of great benefit to those interested in biomedical sciences.
Author : John A. Mol
Publisher : Springer Science & Business Media
ISBN 13 : 0306468328
Total Pages : 309 pages
Book Rating : 4.3/5 (64 download)
Download or read book Biology of the Mammary Gland written by John A. Mol and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author : Keith A. Seely
Publisher :
ISBN 13 :
Total Pages : 166 pages
Book Rating : 4.:/5 (39 download)
Download or read book Cytochalasin D and Acrylamide Alter Protein Secretion and Cytoskeleton in Cultures of Mouse Mammary Epithelium written by Keith A. Seely and published by . This book was released on 1989 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sarah Jane Santos
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.3/5 (129 download)
Download or read book The Regulation of Stat5A Expression and Its Function in the Developing Mouse Mammary Gland written by Sarah Jane Santos and published by . This book was released on 2007 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mathieu Noyer
Publisher :
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.:/5 (428 download)
Download or read book Murine C-erbB2: an Oncogene that Could be a Target for Vaccination Therapy? written by Mathieu Noyer and published by . This book was released on 2006 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Qiao Lin
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (33 download)
Download or read book Regulation of Whey Acidic Protein Gene Expression by Extracellular Matrix and Cell Microenvironment written by Qiao Lin and published by . This book was released on 1994 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John Morrow Shannon
Publisher :
ISBN 13 :
Total Pages : 396 pages
Book Rating : 4.:/5 (27 download)
Download or read book Factors Affecting Functional Differentiation of Mouse Mammary Epithelial Cells in Vitro written by John Morrow Shannon and published by . This book was released on 1979 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:
