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Microvascular Hydrodynamics
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Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Book Synopsis Selected Topics of Computational and Experimental Fluid Mechanics by : Jaime Klapp
Download or read book Selected Topics of Computational and Experimental Fluid Mechanics written by Jaime Klapp and published by Springer. This book was released on 2015-03-05 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains invited lectures and selected contributions presented at the Enzo Levi and XIX Annual Meeting of the Fluid Dynamic Division of the Mexican Physical Society in 2013. It is aimed at fourth year undergraduate and graduate students, and scientists in the fields of physics, engineering and chemistry who are interested in fluid dynamics from an experimental and theoretical point of view. The invited lectures are introductory and avoid the use of complicated mathematics. The fluid dynamics applications include multiphase flow, convection, diffusion, heat transfer, rheology, granular material, viscous flow, porous media flow, geophysics and astrophysics. The material contained in the book includes recent advances in experimental and theoretical fluid dynamics and is suitable for both teaching and research.
Book Synopsis Regulation of Endothelial Barrier Function by : Sarah Y. Yuan
Download or read book Regulation of Endothelial Barrier Function written by Sarah Y. Yuan and published by Biota Publishing. This book was released on 2011-02-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and surrounding extravascular tissues. In addition to regulating blood delivery and perfusion, a major function of vascular endothelia, especially those in exchange microvessels (capillaries and postcapillary venules), is to provide a semipermeable barrier that controls blood–tissue exchange of fluids, nutrients, and metabolic wastes while preventing pathogens or harmful materials in the circulation from entering into tissues. During host defense against infection or tissue injury, endothelial barrier dysfunction occurs as a consequence as well as cause of inflammatory responses. Plasma leakage disturbs fluid homeostasis and impairs tissue oxygenation, a pathophysiological process contributing to multiple organ dysfunction associated with trauma, infection, metabolic disorder, and other forms of disease. In this book, we provide an updated overview of microvascular endothelial barrier structure and function in health and disease. The discussion is initiated with the basic physiological principles of fluid and solute transport across microvascular endothelium, followed by detailed information on endothelial cell–cell and cell–matrix interactions and the experimental techniques that are employed to measure endothelial permeability. Further discussion focuses on the signaling and molecular mechanisms of endothelial barrier responses to various stimulations or drugs, as well as their relevance to several common clinical conditions. Taken together, this book provides a comprehensive analysis of microvascular endothelial cell and molecular pathophysiology. Such information will assist scientists and clinicians in advanced basic and clinical research for improved health care.
Book Synopsis Manual of Venous and Lymphatic Diseases by : Australasian College of Phlebology
Download or read book Manual of Venous and Lymphatic Diseases written by Australasian College of Phlebology and published by CRC Press. This book was released on 2017-11-23 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Manual of Venous and Lymphatic Diseases constitutes a concise but comprehensive and contemporary description of the nature and management of venous and lymphatic diseases. This innovative book instructs the post-graduate trainee in phlebology and is also valuable to undergraduate students wishing to gain a broader knowledge than is available in general surgical texts. Addtionally, it is a useful reference for practising phelebologists, vascular surgeons and imaging specialists. The text covers basic principles, diagnosis and treatment of chronic venous disease, venous thrombo-embolism, lymphoedema and vascular malformations.
Book Synopsis Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute by : National Heart, Lung, and Blood Institute
Download or read book Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute written by National Heart, Lung, and Blood Institute and published by . This book was released on 1979 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Endothelial Barrier Function by : Sarah Y. Yuan
Download or read book Regulation of Endothelial Barrier Function written by Sarah Y. Yuan and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and surrounding extravascular tissues. In addition to regulating blood delivery and perfusion, a major function of vascular endothelia, especially those in exchange microvessels (capillaries and postcapillary venules), is to provide a semipermeable barrier that controls blood-tissue exchange of fluids, nutrients, and metabolic wastes while preventing pathogens or harmful materials in the circulation from entering into tissues. During host defense against infection or tissue injury, endothelial barrier dysfunction occurs as a consequence as well as cause of inflammatory responses. Plasma leakage disturbs fluid homeostasis and impairs tissue oxygenation, a pathophysiological process contributing to multiple organ dysfunction associated with trauma, infection, metabolic disorder, and other forms of disease. In this book, we provide an updated overview of microvascular endothelial barrier structure and function in health and disease. The discussion is initiated with the basic physiological principles of fluid and solute transport across microvascular endothelium, followed by detailed information on endothelial cell-cell and cell-matrix interactions and the experimental techniques that are employed to measure endothelial permeability. Further discussion focuses on the signaling and molecular mechanisms of endothelial barrier responses to various stimulations or drugs, as well as their relevance to several common clinical conditions. Taken together, this book provides a comprehensive analysis of microvascular endothelial cell and molecular pathophysiology. Such information will assist scientists and clinicians in advanced basic and clinical research for improved health care. Table of Contents: Acknowledgments / Introduction / Structure and Function of Exchange Microvessels / Methods for Measuring Permeability / The Endothelial Barrier / Signaling Mechanisms in the Regulation of Endothelial Permeability / Endothelial Barrier Protectors / Pathophysiology and Clinical Relevance / Conclusion / References
Book Synopsis The Physics of Cancer by : Caterina A. M. La Porta
Download or read book The Physics of Cancer written by Caterina A. M. La Porta and published by Cambridge University Press. This book was released on 2017-04-20 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics.
Book Synopsis Neuraxial Therapeutics by : Tony Yaksh
Download or read book Neuraxial Therapeutics written by Tony Yaksh and published by Springer Nature. This book was released on 2024-01-02 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800's to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find Neuraxial Therapeutics, to be an invaluable guide to this treatment modality.
Book Synopsis Dynamics of Blood Cell Suspensions in Microflows by : Annie Viallat
Download or read book Dynamics of Blood Cell Suspensions in Microflows written by Annie Viallat and published by CRC Press. This book was released on 2019-12-09 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to provide a physical perspective of blood microcirculation Draws attention to the potential of this physical approach for novel applications in medicine Edited by specialists in this field, with chapter contributions from subject area specialists
Book Synopsis Computational Hydrodynamics of Capsules and Biological Cells by : Constantine Pozrikidis
Download or read book Computational Hydrodynamics of Capsules and Biological Cells written by Constantine Pozrikidis and published by CRC Press. This book was released on 2010-06-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spanning biological, mathematical, computational, and engineering sciences, computational biofluiddynamics addresses a diverse family of problems involving fluid flow inside and around living organisms, organs, tissue, biological cells, and other biological materials. Computational Hydrodynamics of Capsules and Biological Cells provides a comprehen
Book Synopsis Flow-Dependent Regulation of Vascular Function by : John A Bevan
Download or read book Flow-Dependent Regulation of Vascular Function written by John A Bevan and published by Springer. This book was released on 2013-05-27 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exactly sixty years ago Schretzenmayer provided the first experimental proof that changes in blood ftow can affect the diameter oflarge arteries. Since then, support has been growing for the idea that intraluminal blood ftow plays an important role in regulating not only the tone of blood vessels, but also their caliber and structure. Investigations of the&e phenomena have been given a strong impetus by the discovery that the endothelium can modulate the tone of underlying vascular smooth muscle via the release of a number of vasoactive substances. Investigators often diverge in their opinions regarding the nature of the vascular wall response to blood ftow and the mechanisms involved. This book is the first summary of our state of knowledge and the nature of the research carried out on ftow-related changes. Early chapters review involvement of shear-stress-dependent events in the circulation as a whole. They cover the biophysical principles of ftuid transport, the cellular signal transduction path ways, and the molecular biology and biochemistry of ftow-induced changes in endothelial cells. Later chapters provide an in-depth summary of the regula tion of vascular muscle tone by ftow. They include historical perspectives, evi dence that ftow-induced vasodilation is primarily endothelium-dependent and that it can induce constriction, and details on ftow-dependent regulation in regional vascular beds. Several chapters emphasize the endothelial activation by shear stress and its importance in the control offtow in the microcirculation.
Book Synopsis Computational Fluid and Solid Mechanics by : K.J. Bathe
Download or read book Computational Fluid and Solid Mechanics written by K.J. Bathe and published by Elsevier. This book was released on 2001-05-21 with total page 975 pages. Available in PDF, EPUB and Kindle. Book excerpt: The MIT mission - "to bring together Industry and Academia and to nurture the next generation in computational mechanics is of great importance to reach the new level of mathematical modeling and numerical solution and to provide an exciting research environment for the next generation in computational mechanics." Mathematical modeling and numerical solution is today firmly established in science and engineering. Research conducted in almost all branches of scientific investigations and the design of systems in practically all disciplines of engineering can not be pursued effectively without, frequently, intensive analysis based on numerical computations.The world we live in has been classified by the human mind, for descriptive and analysis purposes, to consist of fluids and solids, continua and molecules; and the analyses of fluids and solids at the continuum and molecular scales have traditionally been pursued separately. Fundamentally, however, there are only molecules and particles for any material that interact on the microscopic and macroscopic scales. Therefore, to unify the analysis of physical systems and to reach a deeper understanding of the behavior of nature in scientific investigations, and of the behavior of designs in engineering endeavors, a new level of analysis is necessary. This new level of mathematical modeling and numerical solution does not merely involve the analysis of a single medium but must encompass the solution of multi-physics problems involving fluids, solids, and their interactions, involving multi-scale phenomena from the molecular to the macroscopic scales, and must include uncertainties in the given data and the solution results. Nature does not distinguish between fluids and solids and does not ever repeat itself exactly.This new level of analysis must also include, in engineering, the effective optimization of systems, and the modeling and analysis of complete life spans of engineering products, from design to fabrication, to possibly multiple repairs, to end of service.
Book Synopsis Transport in Biological Media by : Sid M. Becker
Download or read book Transport in Biological Media written by Sid M. Becker and published by Newnes. This book was released on 2013-05-21 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. - Provides detailed mathematical model development to interpret experiments and provides current modeling practices - Provides a wide range of biological and clinical applications - Includes physiological descriptions of models
Book Synopsis Micro and Nano Flow Systems for Bioanalysis by : Michael W. Collins
Download or read book Micro and Nano Flow Systems for Bioanalysis written by Michael W. Collins and published by Springer Science & Business Media. This book was released on 2012-12-13 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sensewhether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.
Book Synopsis Regulation of Vascular Function by Circulating Blood by : Joseph M. Rifkind
Download or read book Regulation of Vascular Function by Circulating Blood written by Joseph M. Rifkind and published by Frontiers Media SA. This book was released on 2019-08-19 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Research Awards Index written by and published by . This book was released on 1980 with total page 1230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Calcium signalling by : Lars Kaestner
Download or read book Calcium signalling written by Lars Kaestner and published by Springer Science & Business Media. This book was released on 2012-12-02 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book combines general concepts and methods to investigate calcium signalling in cells ranging from molecular biology approaches to manipulation of calcium in living cells. The focus within these methods in on the broad range of fluorescence imaging technology, in particular on optical sectioning techniques and fast image acquisition. In addition to these general guidelines there are application examples in a context beyond calcium signalling in two major fields: investigations of isolated cardiac myocytes and red blood cell related research. While the cellular cardiology section provides snapshots of certain calcium signalling aspects, the red blood cell part presents an overview from the functional identification of calcium-channels to a concept of physiological and pathophysiological relevance.